نتائج البحث - "Trypanosoma brucei gambiense"

1

Evaluation of mechanisms that may generate DNA lesions triggering antigenic variation in African trypanosomes

المؤلفون: Maria Carolina Elias, Emma Briggs, Marcelo Santos da Silva, Galadriel Hovel-Miner, Richard McCulloch

المساهمون: Gubbels, Marc-Jan

المصدر: PLoS Pathogens, Vol 14, Iss 11, p e1007321 (2018)
PLoS Pathogens
Silva, M S D, Hovel-Miner, G A, Briggs, E M, Gubbels, M-J (ed.), Elias, M C & McCulloch, R 2018, ' Evaluation of mechanisms that may generate DNA lesions triggering antigenic variation in African trypanosomes ', PLoS Pathogens, vol. 14, no. 11, e1007321 . https://doi.org/10.1371/journal.ppat.1007321

مصطلحات موضوعية: 0301 basic medicine, Transcription, Genetic, Physiology, Review, Biochemistry, law.invention, chemistry.chemical_compound, law, Transcription (biology), Immune Physiology, Medicine and Health Sciences, lcsh:QH301-705.5, Protozoans, Genetics, Immune System Proteins, Chromosome Biology, Eukaryota, Genomics, Telomere, Antigenic Variation, Nucleic acids, Telomeres, Recombinant DNA, Variant Surface Glycoproteins, Trypanosoma, DNA Replication, lcsh:Immunologic diseases. Allergy, Trypanosoma, Chromosome Structure and Function, DNA recombination, Trypanosoma brucei brucei, DNA transcription, Immunology, Biology, Microbiology, Chromosomes, 03 medical and health sciences, Virology, parasitic diseases, Trypanosoma Brucei, RNA polymerase I, Antigenic variation, Repeated Sequences, Antigens, Molecular Biology, Gene, Immune Evasion, Organisms, DNA replication, Biology and Life Sciences, Proteins, DNA, Cell Biology, Parasitic Protozoans, Trypanosomiasis, African, 030104 developmental biology, chemistry, lcsh:Biology (General), Parasitology, Gene expression, Homologous recombination, lcsh:RC581-607, Trypanosoma Brucei Gambiense

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9e02757053cc2871b3d49cb2125f911
http://europepmc.org/articles/PMC6237402?pdf=render

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2

An orphan kinesin controls trypanosome morphology transitions by targeting FLAM3 to the flagellum

المؤلفون: Ziyin Li, Tai An

المصدر: PLoS Pathogens
PLoS Pathogens, Vol 14, Iss 5, p e1007101 (2018)

مصطلحات موضوعية: 0301 basic medicine, Transcription Elongation, Genetic, Protozoan Proteins, Kinesins, Cell morphology, Pathology and Laboratory Medicine, Biochemistry, Protein Structure, Secondary, RNA interference, Medicine and Health Sciences, Cytoskeleton, Procyclin, lcsh:QH301-705.5, Protozoans, Membrane Glycoproteins, biology, Chemistry, musculoskeletal, neural, and ocular physiology, Microtubule Motors, Eukaryota, Cell biology, Precipitation Techniques, Nucleic acids, Genetic interference, Flagella, Kinesin, Epigenetics, Cellular Structures and Organelles, Pathogens, Research Article, lcsh:Immunologic diseases. Allergy, Pathogen Motility, Trypanosoma, Virulence Factors, Immunology, Trypanosoma brucei brucei, Importin, Trypanosoma brucei, Flagellum, Research and Analysis Methods, Microbiology, 03 medical and health sciences, Molecular Motors, Virology, Genetics, Trypanosoma Brucei, Immunoprecipitation, Amino Acid Sequence, Molecular Biology, urogenital system, Organisms, Biology and Life Sciences, Proteins, Cell Biology, biochemical phenomena, metabolism, and nutrition, biology.organism_classification, Parasitic Protozoans, Cytoskeletal Proteins, 030104 developmental biology, Kinetoplasts, lcsh:Biology (General), bacteria, RNA, Parasitology, Gene expression, lcsh:RC581-607, Carrier Proteins, Sequence Alignment, Trypanosoma Brucei Gambiense

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38c53f1935c97209a1e047859699bf8a
https://pubmed.ncbi.nlm.nih.gov/29813136

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3

CRL4WDR1 Controls Polo-like Kinase Protein Abundance to Promote Bilobe Duplication, Basal Body Segregation and Flagellum Attachment in Trypanosoma brucei

المؤلفون: Huiqing Hu, Qing Zhou, Xianxian Han, Ziyin Li

المصدر: PLoS Pathogens
PLoS Pathogens, Vol 13, Iss 1, p e1006146 (2017)

مصطلحات موضوعية: 0301 basic medicine, Protozoan Proteins, Cell Cycle Proteins, Polo-like kinase, Pathology and Laboratory Medicine, Biochemistry, Ligases, 0302 clinical medicine, RNA interference, Medicine and Health Sciences, Basal body, Cell Cycle and Cell Division, Phosphorylation, Post-Translational Modification, lcsh:QH301-705.5, Protozoans, biology, Cell Cycle, Cullin Proteins, Ubiquitin ligase, Cell biology, Precipitation Techniques, Enzymes, Nucleic acids, Protein Transport, Genetic interference, Flagella, Cell Processes, Ubiquitin ligase complex, Epigenetics, Cellular Structures and Organelles, Pathogens, Cell Division, Research Article, lcsh:Immunologic diseases. Allergy, Pathogen Motility, Trypanosoma, Immunoprecipitation, Virulence Factors, Immunology, Trypanosoma brucei brucei, Flagellum, Trypanosoma brucei, Protein Serine-Threonine Kinases, Research and Analysis Methods, Microbiology, Models, Biological, Gene Expression Regulation, Enzymologic, 03 medical and health sciences, Virology, Proto-Oncogene Proteins, Cell Adhesion, Genetics, Molecular Biology, Biology and life sciences, Organisms, Proteins, Cell Biology, biology.organism_classification, Ubiquitin Ligases, Molecular biology, Basal Bodies, Parasitic Protozoans, Co-Immunoprecipitation, 030104 developmental biology, lcsh:Biology (General), Mutation, biology.protein, Enzymology, RNA, Parasitology, Gene expression, lcsh:RC581-607, 030217 neurology & neurosurgery, Cytokinesis, Trypanosoma Brucei Gambiense

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5282388c37558e02f2b65d3f92afdb95
https://pubmed.ncbi.nlm.nih.gov/28052114

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4

A dual regulatory circuit consisting of S-adenosylmethionine decarboxylase protein and its reaction product controls expression of the paralogous activator prozyme in Trypanosoma brucei

المؤلفون: Margaret A. Phillips, Christopher Leija, Andrew Lemoff, Manish M. Patel, Oleg A. Volkov

المصدر: PLoS Pathogens
PLoS Pathogens, Vol 14, Iss 10, p e1007404 (2018)

مصطلحات موضوعية: 0301 basic medicine, S-Adenosylmethionine, Mutant, Gene Expression, Biochemistry, chemistry.chemical_compound, Methionine, RNA interference, Amino Acids, Enzyme Chemistry, lcsh:QH301-705.5, Protein Metabolism, Protozoans, 2. Zero hunger, chemistry.chemical_classification, Gene knockdown, biology, Organic Compounds, Messenger RNA, Eukaryota, Translation (biology), 3. Good health, Cell biology, Nucleic acids, Chemistry, Genetic interference, Physical Sciences, Epigenetics, Research Article, lcsh:Immunologic diseases. Allergy, Trypanosoma, Adenosylmethionine Decarboxylase, Trypanosoma brucei brucei, Immunology, Enzyme Activators, Trypanosoma brucei, Microbiology, Gene Expression Regulation, Enzymologic, Enzyme Regulation, 03 medical and health sciences, Leucine, Trypanosomiasis, Virology, Trypanosoma Brucei, Genetics, Sulfur Containing Amino Acids, Humans, Molecular Biology, Activator (genetics), Organic Chemistry, Chemical Compounds, Organisms, Biology and Life Sciences, Proteins, biology.organism_classification, Parasitic Protozoans, Protein Subunits, Metabolism, 030104 developmental biology, Enzyme, lcsh:Biology (General), Aliphatic Amino Acids, chemistry, Enzymology, RNA, Protein Translation, Parasitology, lcsh:RC581-607, Polyamine, Trypanosoma Brucei Gambiense

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::786ab9fd39892434362047f957e0f305
https://doi.org/10.1371/journal.ppat.1007404

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5

Carbohydrate-Binding Non-Peptidic Pradimicins for the Treatment of Acute Sleeping Sickness in Murine Models

المؤلفون: Miguel Navarro, Dolores González-Pacanowska, Yasuhiro Igarashi, Víctor M. Castillo-Acosta, Jan Balzarini, Juan Etxebarria, Sandra Liekens, Luis M. Ruiz-Pérez, Niels C. Reichardt

المساهمون: Ministerio de Economía, Industria y Competitividad (España), Red de Investigación Cooperativa en Enfermedades Tropicales (España), Junta de Andalucía, Instituto de Salud Carlos III, Université Catholique de Louvain, Sacks, David

المصدر: PLoS Pathogens
Digital.CSIC. Repositorio Institucional del CSIC
instname
PLoS Pathogens, Vol 12, Iss 9, p e1005851 (2016)

مصطلحات موضوعية: 0301 basic medicine, Glycosylation, Glycobiology, Biochemistry, chemistry.chemical_compound, Lectins, Medicine and Health Sciences, African trypanosomiasis, Post-Translational Modification, lcsh:QH301-705.5, AFRICAN TRYPANOSOMES, Infectivity, chemistry.chemical_classification, Protozoans, Secretory Pathway, biology, Animal Models, Endocytosis, URTICA-DIOICA, Cell Processes, HUMAN-IMMUNODEFICIENCY-VIRUS, TRYPANOSOMA-BRUCEI, Research Article, lcsh:Immunologic diseases. Allergy, Glycan, Trypanosoma, FRONTAL AFFINITY-CHROMATOGRAPHY, 030106 microbiology, Immunology, Mouse Models, Trypanosoma brucei, Research and Analysis Methods, Microbiology, 03 medical and health sciences, Model Organisms, Virology, Microbial Control, Genetics, medicine, Parasitic Diseases, MESSENGER-RNAS, Molecular Biology, Glycoproteins, Pharmacology, Organisms, Biology and Life Sciences, Proteins, Cell Biology, biology.organism_classification, medicine.disease, In vitro, Parasitic Protozoans, 030104 developmental biology, lcsh:Biology (General), chemistry, biology.protein, Parasitology, Antimicrobial Resistance, lcsh:RC581-607, Glycoprotein, Trypanosoma Brucei Gambiense

وصف الملف: Electronic-eCollection

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::693119e865c95d968ebf95e88483e543
https://pubmed.ncbi.nlm.nih.gov/27662652

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6

Cyclin-Dependent Kinase CRK9, Required for Spliced Leader trans Splicing of Pre-mRNA in Trypanosomes, Functions in a Complex with a New L-Type Cyclin and a Kinetoplastid-Specific Protein

المؤلفون: Sung Hee Park, Justin K. Kirkham, Arthur Günzl, Nitika Badjatia, Daniela Luz Ambrósio

المساهمون: University of Connecticut Health Center, The Pennsylvania State University, Universidade de São Paulo (USP)

المصدر: Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
PLoS Pathogens
PLoS Pathogens, Vol 12, Iss 3, p e1005498 (2016)

مصطلحات موضوعية: 0301 basic medicine, Polyadenylation, RNA splicing, Trans-splicing, RNA polymerase II, Protozoology, Biochemistry, Trans-Splicing, Mice, Gene expression, RNA Precursors, Cell Cycle and Cell Division, Post-Translational Modification, Phosphorylation, lcsh:QH301-705.5, Phylogeny, Protozoans, Mice, Inbred BALB C, biology, Cyclin-Dependent Kinases, 3. Good health, Nucleic acids, Cell Processes, Female, RNA Polymerase II, Sequence Analysis, Research Article, lcsh:Immunologic diseases. Allergy, RNA, Spliced Leader, Trypanosoma, Immunology, Trypanosoma brucei brucei, Research and Analysis Methods, Microbiology, 03 medical and health sciences, Cyclin-dependent kinase, Sequence Motif Analysis, Virology, Cyclins, Proliferating Cell Nuclear Antigen, Genetics, Animals, Molecular Biology Techniques, Sequencing Techniques, Gene, Molecular Biology, 030102 biochemistry & molecular biology, Organisms, RNA, Biology and Life Sciences, Proteins, Kinetoplastids, Cell Biology, Molecular biology, Parasitic Protozoans, 030104 developmental biology, lcsh:Biology (General), RNA processing, biology.protein, Parasitology, lcsh:RC581-607, Sequence Alignment, Trypanosoma Brucei Gambiense