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المؤلفون: José R. Franco, Olema Erphas, François Chappuis, Veerle Lejon, Elie A. Akl, Gemma Villanueva, Andreas K. Lindner, Leon Kazumba, Erick Mwamba, Jorge Seixas, Michael P. Barrett, Hanna Bergman, Augustin Kadima Ebeja, Gerardo Priotto, Pere P. Simarro
المصدر: The Lancet Infectious Diseases. 20:e38-e46
مصطلحات موضوعية: Adult, Male, 0301 basic medicine, medicine.medical_specialty, Eflornithine, Adolescent, Combination therapy, Trypanosoma brucei gambiense, 030231 tropical medicine, Antiprotozoal Agents, Disease, World Health Organization, Young Adult, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, medicine, Humans, African trypanosomiasis, Child, Nifurtimox, Intensive care medicine, Aged, Aged, 80 and over, medicine.diagnostic_test, business.industry, Lumbar puncture, Infant, Newborn, Infant, Middle Aged, medicine.disease, Trypanosomiasis, African, 030104 developmental biology, Infectious Diseases, chemistry, Nitroimidazoles, Child, Preschool, Practice Guidelines as Topic, Female, business, Trypanosomiasis, medicine.drug, Pentamidine, Fexinidazole
وصف الملف: application/pdf
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المؤلفون: Monica Cal, Marcel Kaiser, Rasmus Jansson-Löfmark, Pascal Mäser, Mikael Boberg, Michael Ashton
المصدر: PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 15, Iss 7, p e0009583 (2021)مصطلحات موضوعية: 0301 basic medicine, Physiology, Trypanosoma brucei gambiense, RC955-962, Pharmacology, Toxicology, Pathology and Laboratory Medicine, Nervous System, Isomers, 0302 clinical medicine, Medical Conditions, Stereochemistry, Arctic medicine. Tropical medicine, Zoonoses, Medicine and Health Sciences, African trypanosomiasis, Stereoisomers, Cerebrospinal Fluid, Protozoans, Cytotoxicity Assay, biology, Chemistry, Eukaryota, Trypanocidal Agents, Body Fluids, Infectious Diseases, Physical Sciences, Public aspects of medicine, RA1-1270, Anatomy, medicine.drug, Research Article, Neglected Tropical Diseases, Trypanosoma, Eflornithine, 030231 tropical medicine, 030106 microbiology, African Trypanosomiasis, 03 medical and health sciences, Isomerism, Trypanosomiasis, medicine, Parasitic Diseases, Potency, Humans, Protozoan Infections, Public Health, Environmental and Occupational Health, Chemical Compounds, Organisms, Biology and Life Sciences, medicine.disease, biology.organism_classification, Tropical Diseases, In vitro, Parasitic Protozoans, Enantiomers, Racemic mixture, Enantiomer
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae7e42cfd1b1d502d2ef99a4df8c32a7
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المؤلفون: Harry P. de Koning, Fabio Zuccotto, Juan A. Bueren-Calabuig, Juan F. Quintana, Mark C. Field, David Horn
المصدر: PLoS Neglected Tropical Diseases, Vol 14, Iss 7, p e0008458 (2020)
PLoS Neglected Tropical Diseasesمصطلحات موضوعية: Glycerol, 0301 basic medicine, RC955-962, Drug Resistance, Drug resistance, Endoplasmic Reticulum, Biochemistry, 0302 clinical medicine, Ubiquitin, Arctic medicine. Tropical medicine, Amino Acids, Protozoans, 0303 health sciences, Secretory Pathway, biology, Protein Stability, Organic Compounds, Chemistry, Monomers, Eukaryota, ER retention, Trypanocidal Agents, Endocytosis, 3. Good health, Cell biology, Infectious Diseases, medicine.anatomical_structure, Drug development, Cell Processes, Physical Sciences, Cellular Structures and Organelles, Basic Amino Acids, Public aspects of medicine, RA1-1270, Aquaglyceroporins, Research Article, medicine.drug, Trypanosoma, Endosome, Trypanosoma brucei brucei, Immunoblotting, 030231 tropical medicine, Glycerol transport, Molecular Probe Techniques, Trypanosoma brucei, Research and Analysis Methods, 03 medical and health sciences, Lysosome, Trypanosoma Brucei, medicine, Animals, Amino Acid Sequence, Molecular Biology Techniques, Molecular Biology, 030304 developmental biology, 030306 microbiology, Lysine, Organic Chemistry, Organisms, Chemical Compounds, Public Health, Environmental and Occupational Health, Biology and Life Sciences, Proteins, Cell Biology, Polymer Chemistry, biology.organism_classification, Parasitic Protozoans, Trypanosomiasis, African, 030104 developmental biology, biology.protein, Lysosomes, Trypanosoma Brucei Gambiense, Pentamidine
وصف الملف: application/pdf
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المؤلفون: Eleanor Mary Naudzius, Savanah Jessica Diaz, Madison Elle Walsh, Mikhail Martchenko, Danae Schulz, Theodore William Wismar
المصدر: PLoS Neglected Tropical Diseases, Vol 14, Iss 3, p e0007790 (2020)
PLoS Neglected Tropical Diseasesمصطلحات موضوعية: 0301 basic medicine, Life Cycles, RC955-962, Drug Evaluation, Preclinical, Spironolactone, Parasitic Cell Cycles, Spectrum Analysis Techniques, 0302 clinical medicine, Phenothiazines, Zoonoses, Arctic medicine. Tropical medicine, Medicine and Health Sciences, African trypanosomiasis, Procyclin, Protozoans, Pharmaceutics, Eukaryota, Gene Expression Regulation, Developmental, Cell Differentiation, Flow Cytometry, Trypanocidal Agents, Infectious Diseases, Spectrophotometry, Cytophotometry, Public aspects of medicine, RA1-1270, Research Article, medicine.drug, Trypanosoma, Eflornithine, Parasitic Life Cycles, Trypanosoma brucei brucei, 030231 tropical medicine, Library Screening, Biology, Trypanosoma brucei, Research and Analysis Methods, 03 medical and health sciences, Immune system, Drug Therapy, Trypanosomiasis, Trypanosoma Brucei, Parasitic Diseases, Antigenic variation, medicine, Molecular Biology Techniques, Molecular Biology, Pharmacology, Molecular Biology Assays and Analysis Techniques, Drug Screening, Protozoan Infections, fungi, Organisms, Drug Repositioning, Public Health, Environmental and Occupational Health, Biology and Life Sciences, medicine.disease, biology.organism_classification, Virology, Parasitic Protozoans, 030104 developmental biology, Parasitology, Developmental Biology, Trypanosoma Brucei Gambiense
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المؤلفون: Bruno Scherrer, Victor Kande Betu Ku Mesu, Crispin Lumbala, Olaf Valverde Mordt, Nathalie Strub-Wourgaft, Wilfried Mutombo Kalonji, Séverine Blesson, Willy Kuziena, Jean Pierre Fina Lubaki, Steven Lumeya Vuvu, Pathou Nganzobo Ngima, Augustin Kasongo Bonama, François Simon, Lewis Kaninda Badibabi, Jean Louis Lumaliza Solomo, Medard Ilunga, Sonja C. Bernhard, Francis Regongbenga Dama, Josué Amici Heradi, Guylain Mandula, Papy Kavunga Lukula, Clélia Bardonneau, Hélène Mahenzi Mbembo, Digas Ngolo Tete, Sophie Delhomme, Antoine Tarral
المصدر: The Lancet. 391:144-154
مصطلحات موضوعية: Adult, Male, 0301 basic medicine, medicine.medical_specialty, Combination therapy, Trypanosoma brucei gambiense, Population, Administration, Oral, Drug Administration Schedule, 03 medical and health sciences, chemistry.chemical_compound, Eflornithine, Internal medicine, medicine, Humans, African trypanosomiasis, Nifurtimox, education, education.field_of_study, business.industry, General Medicine, Middle Aged, medicine.disease, Trypanocidal Agents, Surgery, Regimen, Treatment Outcome, Trypanosomiasis, African, 030104 developmental biology, chemistry, Nitroimidazoles, Democratic Republic of the Congo, Drug Therapy, Combination, Female, business, Trypanosomiasis, medicine.drug, Fexinidazole
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6Human African trypanosomiasis caused by Trypanosoma brucei gambiense: The first case report in China
المؤلفون: Nian Chen, Jianfu Zhang, Jingjing Xu, Ke Jin, Yali Weng
المصدر: International Journal of Infectious Diseases, Vol 79, Iss, Pp 34-36 (2019)
مصطلحات موضوعية: 0301 basic medicine, Microbiology (medical), Male, China, Eflornithine, Trypanosoma brucei gambiense, 030106 microbiology, World health, lcsh:Infectious and parasitic diseases, 03 medical and health sciences, 0302 clinical medicine, Fatal Outcome, Communicable Diseases, Imported, Recurrence, parasitic diseases, medicine, Animals, Humans, African trypanosomiasis, lcsh:RC109-216, 030212 general & internal medicine, Gabon, business.industry, General Medicine, Middle Aged, medicine.disease, Virology, Trypanocidal Agents, Infectious Diseases, Trypanosomiasis, African, business, medicine.drug
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المؤلفون: Sarah A. Thomas, Lea Ann Dailey, Marcelo A. da Silva, Lisa Sanderson, Shanta J. Persaud, Margarita Valero, Simon L. Croft, Mark R. Christie, Hollie Burrell-Saward, Mehmet Fidanboylu, Chris Lorenz, Bo Liu, Cécile A. Dreiss, Rachel C. Brown, Gayathri N. Sekhar, Vanessa Yardley
المصدر: PLoS Neglected Tropical Diseases
Sanderson, L, Da Silva, M, Sekhar, G, Brown, R, Burrell-Saward, H, Fidanboylu, M, Liu, B, Dailey, L A, Dreiss, C, Lorenz, C, Christie, M, Persaud, S, Yardley, V, Croft, S, Valero, M & Thomas, S 2021, ' Drug reformulation for a neglected disease. The NANOHAT project to develop a safer more effective sleeping sickness drug ', PLoS Neglected Tropical Diseases, vol. 15, no. 4, e0009276 . https://doi.org/10.1371/journal.pntd.0009276
PLoS Neglected Tropical Diseases, Vol 15, Iss 4, p e0009276 (2021)مصطلحات موضوعية: Central Nervous System, Male, Trypanosoma brucei rhodesiense, 0301 basic medicine, Polymers, Physiology, Trypanosoma brucei gambiense, RC955-962, 02 engineering and technology, Pharmacology, Toxicology, Pathology and Laboratory Medicine, Nervous System, Mice, Endocrinology, Arctic medicine. Tropical medicine, Insulin Secretion, Medicine and Health Sciences, African trypanosomiasis, Materials, media_common, 0303 health sciences, Mice, Inbred BALB C, biology, Neglected Diseases, 021001 nanoscience & nanotechnology, Trypanocidal Agents, 3. Good health, Solutions, Chemistry, Infectious Diseases, Macromolecules, Blood-Brain Barrier, Physical Sciences, Toxicity, Female, Public aspects of medicine, RA1-1270, Anatomy, 0210 nano-technology, Research Article, medicine.drug, Drug, Tsetse Flies, media_common.quotation_subject, Materials Science, Material Properties, Trypanosoma brucei, Aqueous Solutions, NANOHAT, Permeability, 03 medical and health sciences, Pharmacokinetics, In vivo, medicine, Animals, Humans, Pentamidine, 030304 developmental biology, Endocrine Physiology, business.industry, Public Health, Environmental and Occupational Health, Neurotoxicity, Biology and Life Sciences, biology.organism_classification, Polymer Chemistry, medicine.disease, Trypanosomiasis, African, 030104 developmental biology, Mixtures, Saline Solutions, Nanocarriers, business
وصف الملف: application/pdf
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المؤلفون: Jiri Keirsse, Magdalena Radwanska, F Kauffmann, Stefan Magez, Théo Baltz, C De Trez, Jennifer Cnops, Eric Muraille
المساهمون: Cellular and Molecular Immunology, Department of Bio-engineering Sciences, Structural Biology Brussels
المصدر: Parasite Immunology. 38(10):642-647
مصطلحات موضوعية: 0301 basic medicine, trypanosomiasis, Trypanosoma brucei gambiense, Trypanosoma spp, 030231 tropical medicine, Immunology, Virulence, Inflammation, Spleen, Apoptosis, Biology, 03 medical and health sciences, Interferon-gamma, Mice, 0302 clinical medicine, Immune system, parasitic diseases, medicine, Animals, Interferon gamma, B-Lymphocytes, Mice, Inbred BALB C, B lymphocyte, Tumor Necrosis Factor-alpha, medicine.disease, Virology, 030104 developmental biology, medicine.anatomical_structure, Trypanosomiasis, African, inflammation, Parasitic disease, Chronic Disease, Parasitology, Tumor necrosis factor alpha, Female, medicine.symptom, Trypanosomiasis, medicine.drug
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المؤلفون: Xinyu Wang, Yiyi Qian, Qiao-ling Ruan, Wenhong Zhang, Jianfei Gu, Muxin Chen, Qin Liu, Qing Lu, Bin Xu
المصدر: Emerging Infectious Diseases
Emerging Infectious Diseases, Vol 24, Iss 2, Pp 400-404 (2018)مصطلحات موضوعية: 0301 basic medicine, Microbiology (medical), China, Epidemiology, Trypanosoma brucei gambiense, 030231 tropical medicine, lcsh:Medicine, Biology, Shanghai, central Africa, parasites, lcsh:Infectious and parasitic diseases, somnolence, 03 medical and health sciences, 0302 clinical medicine, Eflornithine, parasitic diseases, medicine, Research Letter, African trypanosomiasis, lcsh:RC109-216, Gabon, tsetse fly, Nifurtimox, vector-borne infectious, travel, trypomastigotes, African sleeping sickness, lcsh:R, Human African trypanosomiasis, Central africa, Tsetse fly, 030108 mycology & parasitology, medicine.disease, biology.organism_classification, Virology, Infectious Diseases, Human African Trypanosomiasis in Emigrant Returning to China from Gabon, 2017, Africa, fatigue, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3783a761417acf4e338c77b0047e4c28
http://europepmc.org/articles/PMC5782869 -
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المؤلفون: Alexandra G. Raftery, Saloum Jallow, Jean Rodgers, D. G. M. Sutton
المصدر: PLoS Neglected Tropical Diseases, Vol 13, Iss 3, p e0007175 (2019)
PLoS Neglected Tropical Diseasesمصطلحات موضوعية: 0301 basic medicine, Male, Disease, Abortion, Arsenicals, law.invention, chemistry.chemical_compound, Diminazene, Random Allocation, 0302 clinical medicine, Randomized controlled trial, law, Zoonoses, Medicine and Health Sciences, Prospective Studies, Asses, Protozoans, Mammals, education.field_of_study, Pharmaceutics, Triazines, lcsh:Public aspects of medicine, Eukaryota, Trypanocidal Agents, Phenanthridines, Infectious Diseases, Treatment Outcome, Vertebrates, Female, Gambia, Isometamidium chloride, medicine.drug, Research Article, medicine.medical_specialty, Trypanosoma, lcsh:Arctic medicine. Tropical medicine, lcsh:RC955-962, 030231 tropical medicine, Population, Equines, 03 medical and health sciences, Pharmacotherapy, Drug Therapy, Trypanosomiasis, Internal medicine, medicine, Trypanosoma Brucei, Parasitic Diseases, Animals, Horses, education, Protozoan Infections, business.industry, Public Health, Environmental and Occupational Health, Organisms, Biology and Life Sciences, lcsh:RA1-1270, Equidae, medicine.disease, Parasitic Protozoans, 030104 developmental biology, chemistry, Amniotes, Horse Diseases, business, Trypanosoma Brucei Gambiense
وصف الملف: application/pdf
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