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المؤلفون: Mathieu Cayla, Federico Rojas, Keith R. Matthews
المصدر: Rojas, F, Cayla, M & Matthews, K R 2021, ' Basement membrane proteins as a substrate for efficient Trypanosoma brucei differentiation in vitro ', PLoS Neglected Tropical Diseases, vol. 15, no. 4 . https://doi.org/10.1371/journal.pntd.0009284
PLoS Neglected Tropical Diseases, Vol 15, Iss 4, p e0009284 (2021)
PLoS Neglected Tropical Diseasesمصطلحات موضوعية: 0301 basic medicine, Life Cycles, Cellular differentiation, RC955-962, Protozoan Proteins, Matrix (biology), Biochemistry, Parasitic Cell Cycles, Basement Membrane, Extracellular matrix, 0302 clinical medicine, Arctic medicine. Tropical medicine, Protozoans, 0303 health sciences, biology, Chemistry, Cell Cycle, 030302 biochemistry & molecular biology, Eukaryota, Quorum Sensing, Cell Differentiation, Proteases, Cell cycle, Enzymes, Extracellular Matrix, Cell biology, Infectious Diseases, medicine.anatomical_structure, Cellular Structures and Organelles, Public aspects of medicine, RA1-1270, Research Article, Trypanosoma, Parasitic Life Cycles, Trypanosoma brucei brucei, Virulence, Trypanosoma brucei, 03 medical and health sciences, Trypanosoma Brucei, medicine, Animals, Secretion, 030304 developmental biology, Basement membrane, Life Cycle Stages, Organisms, Public Health, Environmental and Occupational Health, Biology and Life Sciences, Proteins, Cell Biology, biology.organism_classification, Parasitic Protozoans, In vitro, Culture Media, 030104 developmental biology, Enzymology, Parasitology, Collagens, 030217 neurology & neurosurgery, Developmental Biology, Trypanosoma Brucei Gambiense
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d44c5e74428dac6efd24020a69b1d0c0
https://www.pure.ed.ac.uk/ws/files/209116413/journal.pntd.0009284.pdf -
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المؤلفون: Terry K. Smith, Peter E. Cockram, Michael P. Barrett, Emily A. Dickie
المساهمون: University of St Andrews. School of Biology, University of St Andrews. Biomedical Sciences Research Complex
المصدر: PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 14, Iss 12, p e0008928 (2020)مصطلحات موضوعية: 0301 basic medicine, Life Cycles, Transamination, RC955-962, Protozoology, 01 natural sciences, Biochemistry, chemistry.chemical_compound, Aromatic Amino Acids, Arctic medicine. Tropical medicine, Aromatic amino acids, Metabolites, African trypanosomiasis, Leishmania major, Amino Acids, chemistry.chemical_classification, Protozoans, biology, Molecular Structure, Organic Compounds, Tryptophan, Eukaryota, Esters, QR Microbiology, Chemistry, Infectious Diseases, Physical Sciences, Protozoan Life Cycles, Public aspects of medicine, RA1-1270, Research Article, RM, Trypanosoma, Cell Physiology, Cell Survival, Trypanosoma brucei brucei, Virulence, Trypanosoma brucei, Microbiology, 03 medical and health sciences, medicine, Trypanosoma Brucei, Humans, Organic Chemistry, Public Health, Environmental and Occupational Health, Chemical Compounds, Organisms, Biology and Life Sciences, Proteins, DAS, Metabolism, Cell Biology, Trypomastigotes, medicine.disease, biology.organism_classification, Parasitic Protozoans, RM Therapeutics. Pharmacology, QR, 0104 chemical sciences, Cell Metabolism, Amino Acid Metabolism, 010404 medicinal & biomolecular chemistry, 030104 developmental biology, chemistry, HeLa Cells, Trypanosoma Brucei Gambiense, Developmental Biology
وصف الملف: application/pdf
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المؤلفون: Angelica Hollunder Klippel, Elizabeth Bilsland, Sandro Roberto Valentini, Rafael M. Couñago, Mario H. Bengtson, Suelen Fernandes Silva, Andree da Silva Santiago, Katlin B. Massirer, Cleslei Fernando Zanelli, P.Z. Ramos
المساهمون: Universidade Estadual Paulista (Unesp), Universidade Estadual de Campinas (UNICAMP)
المصدر: Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
PLoS Neglected Tropical Diseases, Vol 14, Iss 10, p e0008762 (2020)
PLoS Neglected Tropical Diseasesمصطلحات موضوعية: 0301 basic medicine, Nematoda, RC955-962, Drug Evaluation, Preclinical, Protozoan Proteins, Yeast and Fungal Models, Biochemistry, Brugia malayi, chemistry.chemical_compound, 0302 clinical medicine, Arctic medicine. Tropical medicine, Deoxyhypusine synthase, Leishmania major, Brugia Malayi, Enzyme Inhibitors, Enzyme Chemistry, Protozoans, Anthelmintics, Oxidoreductases Acting on CH-NH Group Donors, Crystallography, biology, Physics, Biochemical Cofactors, Eukaryota, Helminth Proteins, Condensed Matter Physics, Enzymes, Infectious Diseases, Bioassays and Physiological Analysis, Experimental Organism Systems, Physical Sciences, Crystal Structure, Saccharomyces Cerevisiae, Public aspects of medicine, RA1-1270, EIF5A, Research Article, Trypanosoma, 030231 tropical medicine, Saccharomyces cerevisiae, Antiprotozoal Agents, Research and Analysis Methods, 03 medical and health sciences, Saccharomyces, Eukaryotic translation, Model Organisms, Brugia, Trypanosoma Brucei, Solid State Physics, Animals, Amino Acid Sequence, Gene, Enzyme Assays, Hypusine, Public Health, Environmental and Occupational Health, Organisms, Fungi, Biology and Life Sciences, Proteins, biology.organism_classification, Invertebrates, Yeast, Parasitic Protozoans, High-Throughput Screening Assays, 030104 developmental biology, chemistry, biology.protein, Animal Studies, Enzymology, Biochemical Analysis, Zoology, Sequence Alignment, Trypanosoma Brucei Gambiense
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5421839c45df0419889cf3653f751e91
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المؤلفون: Harry P. de Koning, Fabio Zuccotto, Juan A. Bueren-Calabuig, Juan F. Quintana, Mark C. Field, David Horn
المصدر: PLoS Neglected Tropical Diseases, Vol 14, Iss 7, p e0008458 (2020)
PLoS Neglected Tropical Diseasesمصطلحات موضوعية: Glycerol, 0301 basic medicine, RC955-962, Drug Resistance, Drug resistance, Endoplasmic Reticulum, Biochemistry, 0302 clinical medicine, Ubiquitin, Arctic medicine. Tropical medicine, Amino Acids, Protozoans, 0303 health sciences, Secretory Pathway, biology, Protein Stability, Organic Compounds, Chemistry, Monomers, Eukaryota, ER retention, Trypanocidal Agents, Endocytosis, 3. Good health, Cell biology, Infectious Diseases, medicine.anatomical_structure, Drug development, Cell Processes, Physical Sciences, Cellular Structures and Organelles, Basic Amino Acids, Public aspects of medicine, RA1-1270, Aquaglyceroporins, Research Article, medicine.drug, Trypanosoma, Endosome, Trypanosoma brucei brucei, Immunoblotting, 030231 tropical medicine, Glycerol transport, Molecular Probe Techniques, Trypanosoma brucei, Research and Analysis Methods, 03 medical and health sciences, Lysosome, Trypanosoma Brucei, medicine, Animals, Amino Acid Sequence, Molecular Biology Techniques, Molecular Biology, 030304 developmental biology, 030306 microbiology, Lysine, Organic Chemistry, Organisms, Chemical Compounds, Public Health, Environmental and Occupational Health, Biology and Life Sciences, Proteins, Cell Biology, Polymer Chemistry, biology.organism_classification, Parasitic Protozoans, Trypanosomiasis, African, 030104 developmental biology, biology.protein, Lysosomes, Trypanosoma Brucei Gambiense, Pentamidine
وصف الملف: application/pdf
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المؤلفون: Falk Butter, Alena Zíková, Clément Regnault, Eva Doleželová, Michael P. Barrett, Brian Panicucci, Mario Dejung, Christian J. Janzen, Michal Levin, Michaela Kunzová
المصدر: PLoS Biology, Vol 18, Iss 6, p e3000741 (2020)
PLoS Biologyمصطلحات موضوعية: 0301 basic medicine, Life Cycles, Proteome, Cellular differentiation, Protozoan Proteins, RNA-binding proteins, Mitochondrion, Protozoology, Biochemistry, 0302 clinical medicine, Adenosine Triphosphate, Amino Acids, Biology (General), Inner mitochondrial membrane, Energy-Producing Organelles, Protein Metabolism, Plant Proteins, Protozoans, Membrane Potential, Mitochondrial, biology, Organic Compounds, General Neuroscience, Methods and Resources, Eukaryota, Cell Differentiation, Cell biology, Mitochondria, Chemistry, Epimastigotes, Physical Sciences, Protozoan Life Cycles, Cellular Structures and Organelles, General Agricultural and Biological Sciences, Oxidoreductases, Oxidation-Reduction, Metabolic Networks and Pathways, Signal Transduction, Alternative oxidase, Cell signaling, Trypanosoma, Proline, QH301-705.5, Cell Respiration, Trypanosoma brucei brucei, Electrons, Oxidative phosphorylation, Trypanosoma brucei, Bioenergetics, Microbiology, General Biochemistry, Genetics and Molecular Biology, Cell Line, Electron Transport, Mitochondrial Proteins, 03 medical and health sciences, Trypanosoma Brucei, Metabolomics, General Immunology and Microbiology, Organic Chemistry, Organisms, Chemical Compounds, Biology and Life Sciences, Proteins, Cyclic Amino Acids, Cell Biology, biology.organism_classification, Parasitic Protozoans, 030104 developmental biology, Metabolism, Glucose, Anaerobic glycolysis, Reactive Oxygen Species, Transcriptome, 030217 neurology & neurosurgery, Developmental Biology, Trypanosoma Brucei Gambiense
وصف الملف: application/pdf
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المؤلفون: Stefan Magez, Carl De Trez, Shahid M. Khan
المساهمون: Department of Bio-engineering Sciences, Cellular and Molecular Immunology
المصدر: PLOS NEGLECTED TROPICAL DISEASES
PLoS Neglected Tropical Diseases, Vol 14, Iss 6, p e0008358 (2020)
PLoS Neglected Tropical Diseasesمصطلحات موضوعية: Protozoan Vaccines, 0301 basic medicine, B Cells, Physiology, RC955-962, Antibodies, Protozoan, Plasma cell, Lymphocyte Activation, Biochemistry, White Blood Cells, Mice, 0302 clinical medicine, Animal Cells, Immune Physiology, Arctic medicine. Tropical medicine, Medicine and Health Sciences, Enzyme-Linked Immunoassays, Alum adjuvant, Memory B cell, Protozoans, B-Lymphocytes, Mice, Inbred BALB C, Immune System Proteins, biology, Malarial Parasites, Eukaryota, medicine.anatomical_structure, Infectious Diseases, Female, Public Health, Cellular Types, Public aspects of medicine, RA1-1270, Antibody, Genetic Background, Research Article, Trypanosoma, ANTIBODY-RESPONSES, Immune Cells, Immunology, Plasma Cells, Trypanosoma brucei brucei, 030231 tropical medicine, B-Lymphocyte Subsets, Antigens, Protozoan, Trypanosoma brucei, Research and Analysis Methods, Antibodies, Host-Parasite Interactions, 03 medical and health sciences, Immune system, Antigen, VARIANT SURFACE GLYCOPROTEIN, Parasitic Diseases, Trypanosoma Brucei, medicine, Animals, Antibody-Producing Cells, Immunoassays, B cell, Immune Evasion, Blood Cells, Environmental and Occupational Health, Organisms, Public Health, Environmental and Occupational Health, Proteins, Biology and Life Sciences, Cell Biology, GAMMA, biology.organism_classification, Parasitic Protozoans, Immunity, Humoral, Mice, Inbred C57BL, Disease Models, Animal, Trypanosomiasis, African, 030104 developmental biology, Immunoglobulin G, Immunologic Techniques, biology.protein, MARGINAL ZONE, Trypanosoma Brucei Gambiense
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المؤلفون: Emir Salas-Sarduy, Lionel Urán Landaburu, Juan José Cazzulo, Gabriela T. Niemirowicz, Fernán Agüero, Adriana K. Carmona, Vanina E. Alvarez
المصدر: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 13, Iss 7, p e0007560 (2019)مصطلحات موضوعية: 0301 basic medicine, RC955-962, Protozoan Proteins, Carboxypeptidases, Biochemistry, Physical Chemistry, Fluorophotometry, purl.org/becyt/ford/1 [https], 0302 clinical medicine, Protein sequencing, Spectrum Analysis Techniques, Arctic medicine. Tropical medicine, Drug Discovery, Medicine and Health Sciences, Fluorescence Resonance Energy Transfer, Enzyme Inhibitors, chemistry.chemical_classification, Protozoans, biology, Neglected Diseases, Eukaryota, INHIBITOR, Enzyme structure, Enzymes, Chemistry, Infectious Diseases, Spectrophotometry, Physical Sciences, Public aspects of medicine, RA1-1270, Research Article, Neglected Tropical Diseases, Chagas disease, Trypanosoma, CARBOXYPEPTIDASE, Antiparasitic, medicine.drug_class, High-throughput screening, Trypanosoma cruzi, 030231 tropical medicine, Trypanosoma brucei brucei, Trypanosoma brucei, Research and Analysis Methods, Fluorescence, Host-Parasite Interactions, 03 medical and health sciences, Inhibitory Concentration 50, parasitic diseases, medicine, Trypanosoma Brucei, Parasitic Diseases, Humans, Chagas Disease, purl.org/becyt/ford/1.6 [https], Protozoan Infections, Chemical Bonding, Public Health, Environmental and Occupational Health, Organisms, Biology and Life Sciences, Proteins, Hydrogen Bonding, TRYPANOSOMA, biology.organism_classification, medicine.disease, Tropical Diseases, Parasitic Protozoans, High-Throughput Screening Assays, 030104 developmental biology, Enzyme, chemistry, Enzyme Structure, Enzymology, Trypanosoma Brucei Gambiense
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43f82d557d2d9a265b8dce6af2420bde
http://dx.plos.org/10.1371/journal.pntd.0007560 -
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المؤلفون: Ralph Minter, Steven Rust, Matthew K. Higgins, Arnaud Tiberghien, Katrien Van Bocxlaer, Amanda F. Francisco, Alan Sandercock, Conor S. Barry, Tristan J. Vaughan, Fatoumatta Jobe, Andrea L. Gonzalez-Munoz, Martin C. Taylor, Olivia J. S. Macleod, Philip W. Howard, Paula MacGregor, Mark Carrington, Francois D'Hooge
المساهمون: MacGregor, Paula [0000-0003-0919-3745], Macleod, Olivia JS [0000-0002-5747-8019], Tiberghien, Arnaud [0000-0002-2936-0515], Carrington, Mark [0000-0002-6435-7266], Apollo - University of Cambridge Repository
المصدر: PLoS Neglected Tropical Diseases, Vol 13, Iss 5, p e0007373 (2019)
PLoS Neglected Tropical Diseasesمصطلحات موضوعية: 0301 basic medicine, Physiology, RC955-962, Toxicology, Pathology and Laboratory Medicine, Biochemistry, law.invention, Benzodiazepines, Mice, 0302 clinical medicine, law, Immune Physiology, Arctic medicine. Tropical medicine, Medicine and Health Sciences, Toxins, African trypanosomiasis, Protozoans, 0303 health sciences, Mice, Inbred BALB C, Immune System Proteins, biology, Antibodies, Monoclonal, Eukaryota, Animal Models, 3. Good health, Infectious Diseases, Experimental Organism Systems, Recombinant DNA, Female, Antibody, Public aspects of medicine, RA1-1270, Research Article, Trypanosoma, Antibody-drug conjugate, medicine.drug_class, Trypanosoma brucei brucei, Toxic Agents, Immunology, 030231 tropical medicine, Antiprotozoal Agents, Mouse Models, Trypanosoma brucei, Research and Analysis Methods, Monoclonal antibody, Microbiology, Antibodies, 03 medical and health sciences, Model Organisms, Therapeutic index, parasitic diseases, Trypanosoma Brucei, Parasitic Diseases, medicine, Animals, Humans, Pyrroles, Animal Models of Disease, 030304 developmental biology, business.industry, Organisms, Public Health, Environmental and Occupational Health, Biology and Life Sciences, Proteins, medicine.disease, biology.organism_classification, Virology, Parasitic Protozoans, Animal Models of Infection, Trypanosomiasis, African, 030104 developmental biology, biology.protein, Animal Studies, business, Trypanosomiasis, Trypanosoma Brucei Gambiense, Conjugate
وصف الملف: application/pdf
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المؤلفون: Maria Carolina Elias, Emma Briggs, Marcelo Santos da Silva, Galadriel Hovel-Miner, Richard McCulloch
المساهمون: Gubbels, Marc-Jan
المصدر: PLoS Pathogens, Vol 14, Iss 11, p e1007321 (2018)
PLoS Pathogens
Silva, M S D, Hovel-Miner, G A, Briggs, E M, Gubbels, M-J (ed.), Elias, M C & McCulloch, R 2018, ' Evaluation of mechanisms that may generate DNA lesions triggering antigenic variation in African trypanosomes ', PLoS Pathogens, vol. 14, no. 11, e1007321 . https://doi.org/10.1371/journal.ppat.1007321مصطلحات موضوعية: 0301 basic medicine, Transcription, Genetic, Physiology, Review, Biochemistry, law.invention, chemistry.chemical_compound, law, Transcription (biology), Immune Physiology, Medicine and Health Sciences, lcsh:QH301-705.5, Protozoans, Genetics, Immune System Proteins, Chromosome Biology, Eukaryota, Genomics, Telomere, Antigenic Variation, Nucleic acids, Telomeres, Recombinant DNA, Variant Surface Glycoproteins, Trypanosoma, DNA Replication, lcsh:Immunologic diseases. Allergy, Trypanosoma, Chromosome Structure and Function, DNA recombination, Trypanosoma brucei brucei, DNA transcription, Immunology, Biology, Microbiology, Chromosomes, 03 medical and health sciences, Virology, parasitic diseases, Trypanosoma Brucei, RNA polymerase I, Antigenic variation, Repeated Sequences, Antigens, Molecular Biology, Gene, Immune Evasion, Organisms, DNA replication, Biology and Life Sciences, Proteins, DNA, Cell Biology, Parasitic Protozoans, Trypanosomiasis, African, 030104 developmental biology, chemistry, lcsh:Biology (General), Parasitology, Gene expression, Homologous recombination, lcsh:RC581-607, Trypanosoma Brucei Gambiense
وصف الملف: application/pdf
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المؤلفون: Corinna Benz, Nadin Fathallah, Henry J Benns, Ashley Connor-Guscott, Winston Lo, Michael D. Urbaniak
المصدر: PLoS ONE
PLoS ONE, Vol 13, Iss 12, p e0206332 (2018)مصطلحات موضوعية: 0301 basic medicine, Protozoan Proteins, Gene Expression, Biochemistry, Green fluorescent protein, Cell Fusion, Database and Informatics Methods, Post-Transcriptional Gene Regulation, 3' Untranslated Regions, Protozoans, Regulation of gene expression, 2. Zero hunger, chemistry.chemical_classification, 0303 health sciences, Multidisciplinary, biology, Messenger RNA, 030302 biochemistry & molecular biology, Eukaryota, Iron Deficiencies, Enzymes, Cell biology, Nucleic acids, Ribosomal RNA, Medicine, Oxidoreductases, Luciferase, Sequence Analysis, Research Article, Trypanosoma, Cell Physiology, Cellular structures and organelles, Bioinformatics, Science, Trypanosoma brucei brucei, Transferrin receptor, Trypanosoma brucei, Research and Analysis Methods, Endocytosis, Cell Line, 03 medical and health sciences, Downregulation and upregulation, Gene Types, Receptors, Transferrin, Trypanosoma Brucei, Genetics, Humans, Gene Regulation, Non-coding RNA, 030304 developmental biology, Reporter gene, Organisms, Biology and Life Sciences, Proteins, Cell Biology, biology.organism_classification, Parasitic Protozoans, 030104 developmental biology, Gene Expression Regulation, chemistry, Transferrin, Enzymology, RNA, Sequence Alignment, Ribosomes, Trypanosoma Brucei Gambiense, Reporter Genes
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07688f03d5f38b25d4878896dc7cacb3
https://doi.org/10.1101/441931