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المؤلفون: Daniel J. Smith, Laura M. Lyall, Keira J.A. Johnston, Angela Silveira, Bruna Gigante, Joey Ward, Amy Ferguson, Hugh Watkins, Bengt Sennblad, Anuj Goel, Philippe Giral, Fabrizio Veglia, Breda Cullen, Damiano Baldassarre, Steve E. Humphries, Julia Morris, Anders Hamsten, Elena Tremoli, Donald M. Lyall, Rona J. Strawbridge, Ulf de Faire, Nicholas Graham, Mark E.S. Bailey, Andries J. Smit
المساهمون: University of Glasgow, Università degli Studi di Milano [Milano] (UNIMI), Centro Cardiologico Monzino [Milano], Dpt di Scienze Cliniche e di Comunità [Milano] (DISCCO), Università degli Studi di Milano [Milano] (UNIMI)-Università degli Studi di Milano [Milano] (UNIMI)-Istituti di Ricovero e Cura a Carattere Scientifico (IRCCS), The Institute of Environmental Medicine [Stockholm] (IMM), Karolinska Institutet [Stockholm], Service d’Endocrinologie, Métabolisme et Prévention des Risques Cardio-Vasculaires [CHU Pitié-Salpêtrière], CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Radcliffe Department of Medicine [Oxford], University of Oxford [Oxford], The Wellcome Trust Centre for Human Genetics [Oxford], University College of London [London] (UCL), University of Edinburgh, Stockholm Bioinformatics Center (SBC), Stockholm University, Uppsala University, University Medical Center Groningen [Groningen] (UMCG), University of Groningen [Groningen], Groningen Kidney Center (GKC)
المصدر: Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
Scientific Reports
Scientific Reports, Nature Publishing Group, 2019, 9 (1), ⟨10.1038/s41598-019-43861-9⟩
Scientific Reports, 9:7339. Nature Publishing Group
Morris, J, Bailey, M E S, Baldassarre, D, Cullen, B, de Faire, U, Ferguson, A, Gigante, B, Giral, P, Goel, A, Graham, N, Hamsten, A, Humphries, S E, Johnston, K J A, Lyall, D M, Lyall, L M, Sennblad, B, Silveira, A, Smit, A J, Tremoli, E, Veglia, F, Ward, J, Watkins, H, Smith, D J & Strawbridge, R J 2019, ' Genetic variation in CADM2 as a link between psychological traits and obesity ', Scientific Reports, vol. 9, no. 1, pp. 7339 . https://doi.org/10.1038/s41598-019-43861-9مصطلحات موضوعية: 0301 basic medicine, Male, Bipolar Disorder, [SDV]Life Sciences [q-bio], Obesity/genetics, LOCI, lcsh:Medicine, Genome-wide association study, Bioinformatics, 0302 clinical medicine, Genetics research, lcsh:Science, RISK, Multidisciplinary, Bipolar Disorder/genetics, Endocrine system and metabolic diseases, Middle Aged, Neuroticism, Anxiety Disorders, 3. Good health, INSIGHTS, Cardiovascular diseases, Medical genetics, Major depressive disorder, Female, Cell Adhesion Molecules/genetics, Depressive Disorder, Major/genetics, Medical Genetics, EXPRESSION, medicine.medical_specialty, Quantitative Trait Loci, Quantitative trait locus, Biology, Polymorphism, Single Nucleotide, Article, 03 medical and health sciences, Risk-Taking, [SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system, Genetic variation, medicine, Humans, Genetic Predisposition to Disease, Bipolar disorder, Obesity, GENOME-WIDE ASSOCIATION, COMMON, METAANALYSIS, Medicinsk genetik, Aged, [SDV.GEN]Life Sciences [q-bio]/Genetics, Depressive Disorder, Major, ENERGY HOMEOSTASIS, lcsh:R, Genetic Variation, medicine.disease, BODY-MASS INDEX, Affect, 030104 developmental biology, VISUALIZATION, lcsh:Q, Psychiatric disorders, Anxiety Disorders/genetics, Cell Adhesion Molecules, 030217 neurology & neurosurgery
وصف الملف: application/pdf
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المؤلفون: Cynthia Sandor, Laura M. Lyall, Valentina Escott-Price, Caleb Webber, Joey Ward, Keira J.A. Johnston, Daniel J. Smith, Michael Conlon O'Donovan, Nicholas Graham, Elizabeth M. Tunbridge, Donald M. Lyall, Paul Harrison, Amy Ferguson, Mark E.S. Bailey, Jill P. Pell, Breda Cullen, Rona J. Strawbridge
المساهمون: Harrison, P
المصدر: Ward, J, Tunbridge, E M, Sandor, C, Lyall, L M, Ferguson, A, Strawbridge, R J, Lyall, D M, Cullen, B, Graham, N, Johnston, K J A, Webber, C, Escott-Price, V, O'Donovan, M, Pell, J P, Bailey, M E S, Harrison, P J & Smith, D J 2020, ' The genomic basis of mood instability : identification of 46 loci in 363,705 UK Biobank participants, genetic correlation with psychiatric disorders, and association with gene expression and function ', Molecular Psychiatry, vol. 25, no. 11, pp. 3091-3099 . https://doi.org/10.1038/s41380-019-0439-8
Molecular psychiatry
Molecular Psychiatryمصطلحات موضوعية: Male, 0301 basic medicine, Linkage disequilibrium, Databases, Factual, Gene Expression, Genome-wide association study, Mice, 0302 clinical medicine, 0303 health sciences, Mental Disorders, Genetic Predisposition to Disease/genetics, Mood Disorders/genetics, Genomics, Middle Aged, Polymorphism, Single Nucleotide/genetics, 3. Good health, Psychiatry and Mental health, Schizophrenia, Major depressive disorder, Female, Adult, medicine.medical_specialty, Biology, Polymorphism, Single Nucleotide, Article, Cellular and Molecular Neuroscience, 03 medical and health sciences, Genetics, medicine, Animals, Humans, Genetic Predisposition to Disease, Bipolar disorder, Psychiatry, Molecular Biology, Aged, 030304 developmental biology, Genetic association, Mental Disorders/genetics, Mood Disorders, Correction, Mental illness, medicine.disease, United Kingdom, Affect, 030104 developmental biology, Mood, Expression quantitative trait loci, 030217 neurology & neurosurgery, Neuroscience, Genome-Wide Association Study
وصف الملف: application/pdf
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المؤلفون: Rona J. Strawbridge, Paul Welsh, Carlos Celis-Morales, Christopher D. Whelan, Jason M.R. Gill, Laura M. Lyall, Joey Ward, Rachana Tank, Amy Ferguson, Jana Anderson, Jonathan Cavanagh, Daniel F. Mackay, Donald M. Lyall, Jill P. Pell, Naveed Sattar, Daniel J. Smith, Patrick B. Mark, Frederick K. Ho
المصدر: Journal of Alzheimer's disease : JAD. 76(4)
مصطلحات موضوعية: 0301 basic medicine, Apolipoprotein E, Oncology, Adult, Male, medicine.medical_specialty, Genotype, Context (language use), Disease, chemistry.chemical_compound, 03 medical and health sciences, 0302 clinical medicine, Apolipoproteins E, Alzheimer Disease, Internal medicine, medicine, Dementia, Humans, Genetic Predisposition to Disease, Risk factor, Allele, 030304 developmental biology, Aged, Biological Specimen Banks, 0303 health sciences, Cholesterol, business.industry, General Neuroscience, General Medicine, Middle Aged, medicine.disease, Biobank, United Kingdom, 3. Good health, Psychiatry and Mental health, Clinical Psychology, 030104 developmental biology, chemistry, Biomarker (medicine), Female, Disease Susceptibility, Geriatrics and Gerontology, business, 030217 neurology & neurosurgery
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bace8d3e30bbc4cef873431fa3b5f799
https://pubmed.ncbi.nlm.nih.gov/32651323 -
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المؤلفون: Daniel J. Smith, Donald M. Lyall, Richard A. I. Bethlehem, Breda Cullen, Nicholas Graham, Graham K. Murray, Laura M. Lyall, Amy Ferguson, Joey Ward, Mark E.S. Bailey, Rona J. Strawbridge, Keira J.A. Johnston
المساهمون: Bethlehem, Richard AI [0000-0002-0714-0685], Strawbridge, Rona J [0000-0001-8506-3585], Johnston, Keira JA [0000-0002-1370-3149], Murray, Graham K [0000-0001-8296-1742], Smith, Daniel J [0000-0002-2267-1951], Apollo - University of Cambridge Repository, Bethlehem, Richard A I [0000-0002-0714-0685], Johnston, Keira J A [0000-0002-1370-3149], Bethlehem, Richard A. I. [0000-0002-0714-0685], Strawbridge, Rona J. [0000-0001-8506-3585], Johnston, Keira J. A. [0000-0002-1370-3149], Murray, Graham K. [0000-0001-8296-1742], Smith, Daniel J. [0000-0002-2267-1951]
المصدر: Translational Psychiatry, Vol 9, Iss 1, Pp 1-9 (2019)
Ward, J, Lyall, L M, Bethlehem, R A I, Ferguson, A, Strawbridge, R J, Lyall, D M, Cullen, B, Graham, N, Johnston, K J A, Bailey, M E S, Murray, G K & Smith, D J 2019, ' Novel genome-wide associations for anhedonia, genetic correlation with psychiatric disorders, and polygenic association with brain structure ', Translational Psychiatry, vol. 9, no. 1, pp. 327 . https://doi.org/10.1038/s41398-019-0635-y
Translational Psychiatryمصطلحات موضوعية: 0301 basic medicine, Male, Multifactorial Inheritance, Anhedonia, Databases, Factual, 45/43, Genome-wide association study, Cohort Studies, 0302 clinical medicine, 692/699/476/1799, 631/208/212/748, Anhedonia/physiology, 0303 health sciences, Depression, Mental Disorders, article, Brain, 692/699/476/1333, Middle Aged, Magnetic Resonance Imaging, 3. Good health, Psychiatry and Mental health, medicine.anatomical_structure, Schizophrenia, Genetic Loci/genetics, Major depressive disorder, Female, medicine.symptom, psychological phenomena and processes, Adult, medicine.medical_specialty, Bipolar disorder, Mental Disorders/diagnostic imaging, Grey matter, behavioral disciplines and activities, lcsh:RC321-571, White matter, 03 medical and health sciences, Cellular and Molecular Neuroscience, 692/699/476/1414, medicine, Humans, Psychiatry, Multifactorial Inheritance/genetics, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, Biological Psychiatry, 030304 developmental biology, Aged, business.industry, Comparative genomics, Brain/diagnostic imaging, Mental illness, medicine.disease, 030104 developmental biology, Genetic Loci, 59/57, business, 030217 neurology & neurosurgery, Diffusion MRI, Genome-Wide Association Study
وصف الملف: application/pdf; application/zip; text/xml
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المؤلفون: Daniel F. Mackay, Laura M. Lyall, Jill P. Pell, Robert Pearsall, Joey Ward, Claire L. Niedzwiedz, Julie Langan Martin, Amy Ferguson, Richard J. Shaw, Mark E.S. Bailey, Breda Cullen, Donald M. Lyall, Nicholas Graham, Rona J. Strawbridge, Daniel J. Smith, Keira J.A. Johnston
المصدر: EBioMedicine
EBioMedicine, Vol 41, Iss, Pp 517-525 (2019)مصطلحات موضوعية: 0301 basic medicine, Adult, Male, medicine.medical_specialty, Research paper, Genotype, Population, lcsh:Medicine, Poison control, Suicide, Attempted, Suicide prevention, Polymorphism, Single Nucleotide, General Biochemistry, Genetics and Molecular Biology, Suicidal Ideation, Cohort Studies, 03 medical and health sciences, 0302 clinical medicine, medicine, Humans, Psychiatry, education, Aged, Biological Specimen Banks, lcsh:R5-920, education.field_of_study, Suicide attempt, Public health, Mental Disorders, lcsh:R, General Medicine, Middle Aged, 16. Peace & justice, Mental health, Biobank, United Kingdom, 3. Good health, Suicide, 030104 developmental biology, 030220 oncology & carcinogenesis, Cohort, Female, lcsh:Medicine (General), Psychology, Genome-Wide Association Study
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المؤلفون: Richard M. Weinshilboum, Daniel J. Smith, Gregory D. Jenkins, Joey Ward, Mark A. Frye, Nicholas Graham, Rudolf Uher, Wenan Chen, Rona J. Strawbridge, Joanna M. Biernacka, Amy Ferguson, Cathryn M. Lewis, Karen Hodgson
المصدر: PLoS ONE
Ward, J, Graham, N, Strawbridge, R J, Ferguson, A, Jenkins, G, Chen, W, Hodgson, K, Frye, M, Weinshilboum, R, Uher, R, Lewis, C M, Biernacka, J & Smith, D J 2018, ' Polygenic risk scores for major depressive disorder and neuroticism as predictors of antidepressant response : Meta-analysis of three treatment cohorts ', PLoS ONE, vol. 13, no. 9, e0203896 . https://doi.org/10.1371/journal.pone.0203896
PLoS ONE, Vol 13, Iss 9, p e0203896 (2018)مصطلحات موضوعية: 0301 basic medicine, Oncology, Male, Multifactorial Inheritance, Heredity, Pharmacogenomic Variants, Genome-wide association study, Cohort Studies, 0302 clinical medicine, Mathematical and Statistical Techniques, Risk Factors, Medicine and Health Sciences, Medicine, Principal Component Analysis, Multidisciplinary, Depression, Pharmaceutics, Drugs, Antidepressants, Genomics, Neuroticism, Antidepressive Agents, 3. Good health, Antidepressant Drug Therapy, Meta-analysis, Cohort, Physical Sciences, Major depressive disorder, Antidepressant, Female, Genetic Load, Statistics (Mathematics), Selective Serotonin Reuptake Inhibitors, Cohort study, Research Article, Biotechnology, Neurological Drug Therapy, medicine.medical_specialty, Science, Research and Analysis Methods, Polymorphism, Single Nucleotide, 03 medical and health sciences, Genomic Medicine, Drug Therapy, Internal medicine, mental disorders, Mental Health and Psychiatry, Genome-Wide Association Studies, Genetics, Humans, Genetic Predisposition to Disease, Statistical Methods, Pharmacology, Depressive Disorder, Major, business.industry, Mood Disorders, Biology and Life Sciences, Computational Biology, Human Genetics, medicine.disease, Genome Analysis, 030104 developmental biology, Pharmacogenomics, business, 030217 neurology & neurosurgery, Mathematics, Meta-Analysis, Genome-Wide Association Study
وصف الملف: application/pdf
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المؤلفون: David M. Howard, Jill P. Pell, Breda Cullen, Daniel J. Smith, Mark E.S. Bailey, Ian J. Deary, Rona J. Strawbridge, Mark Adams, Nicholas Graham, Elizabeth M. Tunbridge, Donald M. Lyall, Amy Ferguson, Paul Harrison, Laura M. Lyall, Keira J.A. Johnston, Andrew M. McIntosh, Joey Ward, Michael Conlon O'Donovan, Jonathan Cavanagh, Valentina Escott-Price, Daniel F. Mackay
المصدر: Translational Psychiatry
Strawbridge, R J, Ward, J, Lyall, L M, Tunbridge, E M, Cullen, B, Graham, N, Ferguson, A, Johnston, K J A, Lyall, D M, Mackay, D, Cavanagh, J, Howard, D M, Adams, M J, Deary, I, Escott-Price, V, O'Donovan, M, McIntosh, A M, Bailey, M E S, Pell, J P, Harrison, P J & Smith, D J 2018, ' Genetics of self-reported risk-taking behaviour, trans-ethnic consistency and relevance to brain gene expression ', Translational Psychiatry, vol. 8, no. 1, pp. 1-11 . https://doi.org/10.1038/s41398-018-0236-1
Translational Psychiatry, Vol 8, Iss 1, Pp 1-11 (2018)مصطلحات موضوعية: 0301 basic medicine, Male, Candidate gene, Multifactorial Inheritance, Bipolar Disorder, Hydrolases, Gene Expression, 0302 clinical medicine, genetics, Biological Specimen Banks, Genetics, pathogenesis, Middle Aged, Biobank, Magnetic Resonance Imaging, White Matter, 3. Good health, White (mutation), Psychiatry and Mental health, Schizophrenia, Cohort, Female, Microtubule-Associated Proteins, Single-nucleotide polymorphism, Nerve Tissue Proteins, Biology, Polymorphism, Single Nucleotide, Article, lcsh:RC321-571, 03 medical and health sciences, Cellular and Molecular Neuroscience, Risk-Taking, medicine, ADHD, Humans, Genetic Predisposition to Disease, Bipolar disorder, Allele, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, Biological Psychiatry, Aged, Calcium-Binding Proteins, medicine.disease, United Kingdom, schizophrenia, 030104 developmental biology, Attention Deficit Disorder with Hyperactivity, Self Report, 030217 neurology & neurosurgery, Genome-Wide Association Study
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المؤلفون: Breda Cullen, Amy Ferguson, Aiden R. Doherty, Jonathan Cavanagh, Rona J. Strawbridge, Donald M. Lyall, Laura M. Lyall, Joey Ward, Daniel J. Smith, Daniel F. Mackay, Claire L. Niedzwiedz, Keira J.A. Johnston, Nicholas Graham, Andrew M. McIntosh, Stephany M. Biello, Cathy A. Wyse, Jill P. Pell, Mark E.S. Bailey
المصدر: Ferguson, A, Lyall, L M, Ward, J, Strawbridge, R J, Cullen, B, Graham, N, Niedzwiedz, C L, Johnston, K J A, MacKay, D, Biello, S M, Pell, J P, Cavanagh, J, McIntosh, A M, Doherty, A, Bailey, M E S, Lyall, D M, Wyse, C A & Smith, D J 2018, ' Genome-Wide Association Study of Circadian Rhythmicity in 71,500 UK Biobank Participants and Polygenic Association with Mood Instability ', EBioMedicine, vol. 35 . https://doi.org/10.1016/j.ebiom.2018.08.004
مصطلحات موضوعية: 0301 basic medicine, Adult, Multifactorial Inheritance, Mood instability, Quantitative Trait Loci, Genome-wide association study, Biology, Polymorphism, Single Nucleotide, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, 0302 clinical medicine, README, Humans, Circadian rhythm, Relative amplitude, Aged, Biological Specimen Banks, Genetics, Mood Disorders, Mental Disorders, General Medicine, Middle Aged, Biobank, Circadian Rhythm, 030104 developmental biology, Phenotype, Polygenic risk score, 030217 neurology & neurosurgery, Genome-Wide Association Study
وصف الملف: application/pdf
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المؤلفون: Julia Morris, Nicholas Graham, Mark E.S. Bailey, Daniel J. Smith, Soddy Sau Yu Leung, Breda Cullen, Rona J. Strawbridge, Keira J.A. Johnston, Laura M. Lyall, Donald M. Lyall, Joey Ward, Amy Ferguson
المصدر: Genes
Volume 11
Issue 11
Genes, Vol 11, Iss 1326, p 1326 (2020)
Morris, J, Leung, S S Y, Bailey, M E S, Cullen, B, Ferguson, A, Graham, N, Johnston, K J A, Lyall, D M, Lyall, L M, Ward, J, Smith, D J & Strawbridge, R J 2020, ' Exploring the role of contactins across psychological, psychiatric and cardiometabolic traits within uk biobank ', Genes, vol. 11, no. 11, 1326, pp. 1-17 . https://doi.org/10.3390/genes11111326مصطلحات موضوعية: 0301 basic medicine, contactins, Blood Pressure, Comorbidity, Body Mass Index, single nucleotide polymorphisms, 0302 clinical medicine, Genetics (clinical), Biological Specimen Banks, education.field_of_study, Mental Disorders, Absolute risk reduction, Type 2 diabetes, Biobank, Neuroticism, Cardiometabolic diseases, Phenotype, psychiatric disorders, Cardiovascular Diseases, Hypertension, cardiometabolic diseases, UK Biobank, medicine.medical_specialty, hypertension, lcsh:QH426-470, Population, Polymorphism, Single Nucleotide, Article, 03 medical and health sciences, Contactin 1, Contactins, Genetic variation, Genetics, medicine, Genetic Predisposition to Disease, Obesity, education, Psychiatry, Genetic association, Cardiometabolic Risk Factors, Single nucleotide polymorphisms, Mental illness, medicine.disease, United Kingdom, lcsh:Genetics, 030104 developmental biology, Diabetes Mellitus, Type 2, genetic variation, gene expression, Gene expression, Psychiatric disorders, 030217 neurology & neurosurgery, Genome-Wide Association Study
وصف الملف: application/pdf