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1
المؤلفون: Tadayoshi Okimoto, Takahiro Hiratsuka, Shusaku Kurogi, Masafumi Inomata, Tomohisa Uchida, Daisuke Kakisako, Teijiro Hirashita, Masatsugu Moriyama, Chisato Nakada, Yoshiyuki Tsukamoto, Naoki Hijiya, Yuka Hirashita, Tsuyoshi Etoh, Tomonori Akagi, Masaaki Kodama, Yoshitake Ueda, Kazuhiro Mizukami, Yoko Kudo, Koichi Honda, Kazunari Murakami, Hidefumi Shiroshita
المصدر: Laboratory Investigation. 101:1036-1047
مصطلحات موضوعية: Male, 0301 basic medicine, MAPK/ERK pathway, MAP Kinase Signaling System, Pyridones, Colorectal cancer, Antineoplastic Agents, Pyrimidinones, Pathology and Forensic Medicine, Mice, 03 medical and health sciences, 0302 clinical medicine, Mice, Inbred NOD, Cell Line, Tumor, Animals, Humans, Medicine, Epidermal growth factor receptor, Phosphorylation, Protein Kinase Inhibitors, Molecular Biology, Aged, Aged, 80 and over, Mitogen-Activated Protein Kinase Kinases, Trametinib, Ribosomal Protein S6, biology, business.industry, MEK inhibitor, Cell Biology, Middle Aged, medicine.disease, digestive system diseases, Blot, 030104 developmental biology, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, Ribosomal protein s6, Cancer cell, Cancer research, biology.protein, Female, Colorectal Neoplasms, business
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المؤلفون: Frederic S Arendrup, Jens S. Andersen, Marta Montes, Anders H. Lund, Sarunas Tumas, Lea M. Harder, Anders Jacobsen Skanderup, Neha Rohatgi, Bettina Mentz, Michal Lubas
المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Nature Communications
Montes, M, Lubas, M, Arendrup, F S, Mentz, B, Rohatgi, N, Tumas, S, Harder, L M, Skanderup, A J, Andersen, J S & Lund, A H 2021, ' The long non-coding RNA MIR31HG regulates the senescence associated secretory phenotype ', Nature Communications, vol. 12, no. 1, 2459 . https://doi.org/10.1038/s41467-021-22746-4
Montes, M, Lubas, M, Arendrup, F S, Mentz, B, Rohatgi, N, Tumas, S, Harder, L M, Skanderup, A J, Andersen, J S & Lund, A H 2021, ' The long non-coding RNA MIR31HG regulates the senescence associated secretory phenotype ', Nature Communications, vol. 12, no. 1, 2459, pp. 1-17 . https://doi.org/10.1038/s41467-021-22746-4مصطلحات موضوعية: 0301 basic medicine, Translation, Aging, General Physics and Astronomy, 0302 clinical medicine, Transcription (biology), Neoplasms, Aging/genetics, Phosphorylation, Cellular Senescence, Multidisciplinary, Kinase, Cell Transformation, Neoplastic/genetics, Cyclin-Dependent Kinase Inhibitor p16/biosynthesis, Translation (biology), Neoplasms/genetics, Cell biology, Gene Expression Regulation, Neoplastic, Proto-Oncogene Proteins B-raf/metabolism, Cell Transformation, Neoplastic, Cellular Senescence/genetics, 030220 oncology & carcinogenesis, RNA, Long Noncoding, Proto-Oncogene Proteins B-raf, Senescence, Science, Repressor, Biology, Ribosomal Protein S6 Kinases, 90-kDa, Article, General Biochemistry, Genetics and Molecular Biology, Cell Line, Cell Proliferation/genetics, 03 medical and health sciences, Paracrine signalling, Humans, Secretion, RNA, Long Noncoding/genetics, Cyclin-Dependent Kinase Inhibitor p16, Cell Proliferation, fungi, Oncogenes, General Chemistry, Gene Expression Regulation, Neoplastic/genetics, 030104 developmental biology, Ribosomal Protein S6 Kinases, 90-kDa/metabolism, Long non-coding RNAs, Y-Box-Binding Protein 1, Y-Box-Binding Protein 1/metabolism
وصف الملف: application/pdf
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المؤلفون: Caitlin MacRae, Cameron J. Mitchell, David Cameron-Smith, Randall F. D'Souza, Troy L. Merry, James F. Markworth, Chantal A. Pileggi, Vandre C. Figueiredo, Nina Zeng
المصدر: American Journal of Physiology-Cell Physiology. 320:C591-C601
مصطلحات موضوعية: Male, 0301 basic medicine, medicine.medical_specialty, Time Factors, Physiology, Cell Cycle Proteins, 030209 endocrinology & metabolism, mTORC1, Mechanistic Target of Rapamycin Complex 1, DEPTOR, Quadriceps Muscle, Immobilization, 03 medical and health sciences, 0302 clinical medicine, Atrophy, Internal medicine, Humans, Medicine, Phosphorylation, Adaptor Proteins, Signal Transducing, Ribosomal Protein S6, business.industry, Nuclear Proteins, Ribosomal Protein S6 Kinases, 70-kDa, Cell Biology, Middle Aged, Milk Proteins, Postprandial Period, medicine.disease, Protein supplementation, Muscle atrophy, MicroRNAs, Muscular Atrophy, Treatment Outcome, 030104 developmental biology, Endocrinology, Dietary protein, Postprandial, Dietary Supplements, medicine.symptom, business, Signal Transduction
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d1abbc20b214b60a6a77c771fe674cb
https://doi.org/10.1152/ajpcell.00284.2020 -
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المؤلفون: Sophie L Allen, Gareth G. Lavery, Leigh Breen, Janet M. Lord, Ryan N. Marshall, Sophie J Edwards
المصدر: American Journal of Physiology-Cell Physiology. 321:C26-C37
مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Aging, Physiology, Muscle Fibers, Skeletal, Muscle Proteins, Models, Biological, Cell Line, Cellular protein, In vitro model, Mice, 03 medical and health sciences, 0302 clinical medicine, Peptide Elongation Factor 2, Leucine, Animals, Humans, Muscle, Skeletal, Aged, Muscle loss, Interleukin-6, Chemistry, Ribosomal Protein S6 Kinases, 70-kDa, Cell Biology, In vitro, Culture Media, Cell biology, Muscular Atrophy, C-Reactive Protein, 030104 developmental biology, Protein Biosynthesis, Proteolysis, Insulin Resistance, Proto-Oncogene Proteins c-akt, 030217 neurology & neurosurgery, Ex vivo, Signal Transduction
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de7c27146603143134f39b73c9479925
https://doi.org/10.1152/ajpcell.00093.2021 -
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المؤلفون: Yu Ishima, Tatsuhiro Ishida, Kiyoshi Eshima, Yoshino Kawaguchi, Hidenori Ando, Taro Shimizu, Sherif E. Emam
المصدر: Biological and Pharmaceutical Bulletin. 44:844-852
مصطلحات موضوعية: 0301 basic medicine, Bicarbonate, Urinary system, Programmed Cell Death 1 Receptor, Administration, Oral, Pharmaceutical Science, Urine, Pharmacology, 03 medical and health sciences, chemistry.chemical_compound, Antineoplastic Agents, Immunological, 0302 clinical medicine, Oral administration, In vivo, Cell Line, Tumor, Neoplasms, Tumor-Associated Macrophages, Extracellular, Animals, Citrates, Lymphocytes, Immune Checkpoint Inhibitors, Mice, Inbred BALB C, Sodium bicarbonate, Ribosomal Protein S6 Kinases, Antibodies, Monoclonal, Alkalinizing agent, General Medicine, Hydrogen-Ion Concentration, Mice, Inbred C57BL, Bicarbonates, 030104 developmental biology, chemistry, 030220 oncology & carcinogenesis, Female
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::293b153437eae510f7c536f68abd0842
https://doi.org/10.1248/bpb.b21-00076 -
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المؤلفون: Gum Hwa Lee, Alena Savonenko, Paul F. Worley, Po Yu Chen, Susan M. Resnick, Bo Xiao, Joo Min Park, Kevin T. Chen, David J. Linden, Chan Hyun Na, Karen K. Szumlinski, Raozhou Lin, Lisa N. Learman, Akhilesh Pandey, Juan C. Troncoso, Santosh Renuse
المصدر: Biological psychiatry, vol 89, iss 11
مصطلحات موضوعية: 0301 basic medicine, Dopamine and cAMP-Regulated Phosphoprotein 32, P70-S6 Kinase 1, mTORC1, Mechanistic Target of Rapamycin Complex 1, Medical and Health Sciences, Immediate early gene, 03 medical and health sciences, 0302 clinical medicine, Dopamine, Dopamine D1, Receptors, Behavioral and Social Science, medicine, Humans, 2.1 Biological and endogenous factors, Social behavior, Phosphorylation, Aetiology, Biological Psychiatry, Psychiatry, biology, Kinase, Ribosomal Protein S6 Kinases, TOR Serine-Threonine Kinases, Psychology and Cognitive Sciences, Neurosciences, S6K1, Biological Sciences, DARPP-32, Brain Disorders, 030104 developmental biology, Dopamine receptor, Neurological, D(1) dopamine receptor, biology.protein, biological phenomena, cell phenomena, and immunity, Neuroscience, 030217 neurology & neurosurgery, Signal Transduction, RHEB, medicine.drug
وصف الملف: application/pdf
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المؤلفون: Li Shuangjia, Li Yanmei, Li Shuang, Qingyun Tan, Qingdong Wang, Gao Zhanqun, Dongwei Wang, Yang Liu
المصدر: Cardiovascular Toxicology. 21:655-668
مصطلحات موضوعية: 0301 basic medicine, Chemistry, P70-S6 Kinase 1, 030204 cardiovascular system & hematology, Toxicology, Angiotensin II, Muscle hypertrophy, Cell biology, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Atrial natriuretic peptide, Ribosomal protein s6, Cardiology and Cardiovascular Medicine, Indoleamine 2,3-dioxygenase, Molecular Biology, Protein kinase B, PI3K/AKT/mTOR pathway
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المؤلفون: Soo Jin Kim, Se-Myo Park, Jung-Hwa Oh, Mi-Sun Choi, Hyun Jegal, Hyoung-Yun Han, Jun-Ho Ahn, Seokjoo Yoon, Hyun-Soo Cho, Jaehwan Ahn
المصدر: Toxicology Letters. 342:73-84
مصطلحات موضوعية: 0301 basic medicine, Cell Survival, MAP Kinase Kinase 4, ATG5, Levofloxacin, Pharmacology, Toxicology, Piperazines, Antimalarials, 03 medical and health sciences, 0302 clinical medicine, Autophagy, Humans, Naphthyridines, Serotonin and Noradrenaline Reuptake Inhibitors, Cytotoxicity, PI3K/AKT/mTOR pathway, Gene knockdown, Tumor Necrosis Factor-alpha, Chemistry, TOR Serine-Threonine Kinases, Ribosomal Protein S6 Kinases, 70-kDa, Chloroquine, Hep G2 Cells, General Medicine, Triazoles, 030104 developmental biology, Gene Expression Regulation, Toxicity, Hepatocytes, Phosphorylation, Tumor necrosis factor alpha, 030217 neurology & neurosurgery, Fluoroquinolones
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المؤلفون: Ying Fang, Delin Mo, Shufang Cai, Qi Zhu, Feng Liang, Yaosheng Chen, Renqiang Yuan, Junyan Zhang, Keren Chen, Xiaorong Luo
المصدر: The FASEB Journal. 34:12367-12378
مصطلحات موضوعية: Male, 0301 basic medicine, Satellite Cells, Skeletal Muscle, Myoblasts, Skeletal, P70-S6 Kinase 1, Biology, Muscle Development, Ribosomal Protein S6 Kinases, 90-kDa, Biochemistry, Mice, 03 medical and health sciences, 0302 clinical medicine, Genetics, medicine, Animals, HMGB2 Protein, Regeneration, Myocyte, Kinase activity, Muscle, Skeletal, Molecular Biology, Cells, Cultured, Myogenin, Myogenesis, Skeletal muscle, Cell biology, Mice, Inbred C57BL, 030104 developmental biology, medicine.anatomical_structure, Ribosomal protein s6, Female, MYF5, 030217 neurology & neurosurgery, Biotechnology
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المؤلفون: Hirofumi Jono, Hideyuki Saito, Michiko Yamaoka, Akitake Mukasa, Naofumi Ito, Naoki Shinojima, Takuichiro Hide, Kunimasa Ohta, Yuki Ito, Yuki Shirakawa
المصدر: Cancer Science
مصطلحات موضوعية: Adult, Male, 0301 basic medicine, cancer stem cell, endocrine system, Cancer Research, Somatic cell, Population, Biology, 03 medical and health sciences, 0302 clinical medicine, Cell, Molecular, and Stem Cell Biology, SOX2, Ribosomal protein, Cancer stem cell, Glioma, medicine, Humans, Child, education, Aged, Ribosomal Protein S6, education.field_of_study, Brain Neoplasms, fungi, glioblastoma, Infant, Original Articles, General Medicine, Middle Aged, medicine.disease, GBM stem‐like cells, 030104 developmental biology, ribosome, Oncology, 030220 oncology & carcinogenesis, Ribosomal protein s6, Neoplastic Stem Cells, Cancer research, Original Article, Female, Stem cell