نتائج البحث - "Toshiaki Takahashi"

1

First‐line pembrolizumab vs chemotherapy in metastatic non‐small‐cell lung cancer: KEYNOTE‐024 Japan subset*

المصدر: Cancer Science
Cancer Sci

مصطلحات موضوعية: 0301 basic medicine, Male, Cancer Research, Lung Neoplasms, medicine.medical_treatment, Programmed Cell Death 1 Receptor, non‐small‐cell lung carcinoma, Pembrolizumab, Kaplan-Meier Estimate, Gastroenterology, Deoxycytidine, B7-H1 Antigen, Carboplatin, 0302 clinical medicine, Antineoplastic Agents, Immunological, Japan, Carcinoma, Non-Small-Cell Lung, Antineoplastic Combined Chemotherapy Protocols, Anaplastic Lymphoma Kinase, Neoplasm Metastasis, Aged, 80 and over, Cross-Over Studies, Hazard ratio, General Medicine, Middle Aged, PD-L1 protein, Progression-Free Survival, Oncology, 030220 oncology & carcinogenesis, non-small-cell lung carcinoma, Carcinoma, Squamous Cell, Female, Original Article, Non small cell, pembrolizumab, Adult, medicine.medical_specialty, Paclitaxel, First line, Pemetrexed, Antibodies, Monoclonal, Humanized, Drug Administration Schedule, 03 medical and health sciences, Drug Therapy, Clinical Research, Internal medicine, medicine, Confidence Intervals, Humans, Lung cancer, Adverse effect, PD‐L1 protein, Aged, Chemotherapy, business.industry, Genes, erbB-1, Original Articles, medicine.disease, Survival Analysis, Gemcitabine, Confidence interval, Retraction, 030104 developmental biology, treatment outcome, Cisplatin, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4692f872031566a6ba7ec9528f7d1191
https://doi.org/10.1111/cas.15144

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2

A Phase II Study to Assess the Efficacy of Osimertinib in Patients With EGFR Mutation-positive NSCLC Who Developed Isolated CNS Progression (T790M-negative or Unknown) During First- or Second-generation EGFR-TKI or Systemic Disease Progression (T790M-negative) After Treatment With First- or Second-generation EGFR-TKI and Platinum-based Chemotherapy (WJOG12819L)

المؤلفون: Terufumi Kato, Yasutaka Watanabe, D. Fujimoto, Kaname Nosaki, Masayuki Takeda, Mototsugu Shimokawa, Hiroshi Tanaka, Kazuo Hasegawa, Atsushi Nakamura, Naohiko Hamaguchi, Koichi Azuma, Isamu Okamoto, Daisuke Hayakawa, Kakuhiro Yamaguchi, Nobuyuki Yamamoto, Kazuhiko Nakagawa, Motoko Tachihara, Toshiaki Takahashi, Yoshihito Kogure

المصدر: Clinical Lung Cancer. 22:376-380

مصطلحات موضوعية: 0301 basic medicine, Pulmonary and Respiratory Medicine, Oncology, Cancer Research, medicine.medical_specialty, Lung Neoplasms, medicine.drug_class, medicine.medical_treatment, Phases of clinical research, Tyrosine-kinase inhibitor, Central Nervous System Neoplasms, Cohort Studies, 03 medical and health sciences, T790M, 0302 clinical medicine, Carcinoma, Non-Small-Cell Lung, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, Osimertinib, Prospective Studies, Lung cancer, Acrylamides, Chemotherapy, Aniline Compounds, business.industry, Standard treatment, medicine.disease, Progression-Free Survival, respiratory tract diseases, ErbB Receptors, 030104 developmental biology, 030220 oncology & carcinogenesis, Mutation, Cohort, Disease Progression, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f1217b6719037c7d3a691311cec275d
https://doi.org/10.1016/j.cllc.2020.12.009

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3

Cumulative incidence of venous thromboembolism in patients with advanced cancer in prospective observational study

المؤلفون: Yoshihiro Miki, Shota Omori, Masakazu Abe, Masahito Ogiku, Yasuomi Satake, Keita Mori, Hirotsugu Kenmotsu, Toshiaki Takahashi, Hideto Ochiai, Toshio Nakamura, Hirofumi Yasui, Masakazu Takagi, Akifumi Notsu, Takahiro Tsushima

المصدر: Cancer Medicine, Vol 10, Iss 3, Pp 895-904 (2021)
Cancer Medicine

مصطلحات موضوعية: Male, 0301 basic medicine, Cancer Research, medicine.medical_treatment, chemotherapy, 0302 clinical medicine, Japan, Risk Factors, Neoplasms, Antineoplastic Combined Chemotherapy Protocols, Clinical endpoint, advanced cancer, Medicine, pulmonary thromboembolism, Cumulative incidence, Prospective Studies, Original Research, Aged, 80 and over, Incidence, Incidence (epidemiology), Middle Aged, Prognosis, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Oncology, 030220 oncology & carcinogenesis, Female, medicine.symptom, Adult, medicine.medical_specialty, venous thromboembolism, lcsh:RC254-282, Asymptomatic, deep vein thrombosis, 03 medical and health sciences, Internal medicine, Humans, Radiology, Nuclear Medicine and imaging, cardiovascular diseases, Lung cancer, Aged, Chemotherapy, business.industry, Clinical Cancer Research, equipment and supplies, medicine.disease, Confidence interval, 030104 developmental biology, Observational study, business, Follow-Up Studies

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f4bd848b75b288c6e16da1682981b51
https://doi.org/10.1002/cam4.3670

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4

Detection of programmed cell death-ligand 1 using 22C3 antibody in patients with unresectable stage III non-small cell lung cancer receiving chemoradiotherapy

المؤلفون: Hiroaki Kodama, Tateaki Naito, Hirotsugu Kenmotsu, Hideyuki Harada, Shota Omori, Kazushige Wakuda, Toshiaki Takahashi, Michitoshi Yabe, Haruki Kobayashi, Koji Muramatsu, Tetsuo Shimizu, Akira Ono, Nobuaki Mamesaya, Taichi Miyawaki, Eriko Miyawaki, Yasuhiro Gon, Naoya Nishioka, Takashi Sugino, Haruyasu Murakami

المصدر: International Journal of Clinical Oncology. 26:659-669

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7c975ec864ca94bc4feff7af6b7799c
https://doi.org/10.1007/s10147-020-01856-x

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5

Efficacy of pembrolizumab in patients with brain metastasis caused by previously untreated non-small cell lung cancer with high tumor PD-L1 expression

المؤلفون: Michitoshi Yabe, Haruyasu Murakami, Takahisa Kawamura, Taichi Miyawaki, Tateaki Naito, Eriko Miyawaki, Toshiaki Takahashi, Hirotsugu Kenmotsu, Hideyuki Harada, Kazushige Wakuda, Naoya Nishioka, Akira Ono, Masahiro Endo, Nobuaki Mamesaya, Shota Omori, Haruki Kobayashi, Hiroaki Kodama, Yasuhiro Gon

المصدر: Lung Cancer. 151:60-68

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2ad7ba3e9b345637d5e3131f845ae36
https://doi.org/10.1016/j.lungcan.2020.11.009

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6

Randomized Phase III Study of Irinotecan Plus Cisplatin Versus Etoposide Plus Cisplatin for Completely Resected High-Grade Neuroendocrine Carcinoma of the Lung: JCOG1205/1206

المصدر: Journal of Clinical Oncology. 38:4292-4301

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ecbfbe2ecf23f8fd865094f099bc62e
https://doi.org/10.1200/jco.20.01806

7

Unfavorable impact of decreased muscle quality on the efficacy of immunotherapy for advanced non‐small cell lung cancer

المؤلفون: Taichi Miyawaki, Eriko Miyawaki, Tateaki Naito, Naoya Nishioka, Hiroaki Kodama, Kazushige Wakuda, Haruyasu Murakami, Nobuaki Mamesaya, Koichi Takayama, Shota Omori, Akira Ono, Hirotsugu Kenmotsu, Haruki Kobayashi, Toshiaki Takahashi, Keita Mori, Akifumi Notsu

المصدر: Cancer Medicine

مصطلحات موضوعية: 0301 basic medicine, non‐small cell lung cancer, Adult, Male, Cancer Research, medicine.medical_specialty, muscle quantity, Lung Neoplasms, Time Factors, medicine.medical_treatment, Urology, muscle quality, 03 medical and health sciences, 0302 clinical medicine, Lumbar, PD‐1/PD‐L1 inhibitor, Hounsfield scale, myosteatosis, Carcinoma, Non-Small-Cell Lung, Medicine, Humans, Radiology, Nuclear Medicine and imaging, Lung cancer, Muscle, Skeletal, Immune Checkpoint Inhibitors, Original Research, Aged, Retrospective Studies, Aged, 80 and over, business.industry, Therapeutic effect, Skeletal muscle, Clinical Cancer Research, Immunotherapy, Middle Aged, medicine.disease, Progression-Free Survival, 030104 developmental biology, medicine.anatomical_structure, Oncology, 030220 oncology & carcinogenesis, Body Composition, Female, Non small cell, business, Tomography, X-Ray Computed, Body mass index

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9abfd75522ced60911eeca154a6d003b
http://europepmc.org/articles/PMC7826480

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8

Lorlatinib in previously treated anaplastic lymphoma kinase‐rearranged non–small cell lung cancer: Japanese subgroup analysis of a global study

المؤلفون: Mie Suzuki, Hidetoshi Hayashi, Makoto Nishio, Gerson Peltz, Takashi Nagasawa, Toyoaki Hida, Takashi Seto, Kei Fukuhara, Masayuki Ohkura, Miyako Satouchi, Yasushi Goto, Holger Thurm, Masahiro Morise, Naoyuki Nogami, Toshiaki Takahashi, Seiji Niho, Jun Sakakibara-Konishi

المصدر: Cancer Science

مصطلحات موضوعية: 0301 basic medicine, Alectinib, Oncology, Cancer Research, Aminopyridines, non–small‐cell lung, carcinoma, Proto-Oncogene Mas, tyrosine kinase inhibitor, 0302 clinical medicine, Carcinoma, Non-Small-Cell Lung, hemic and lymphatic diseases, Medicine, Anaplastic lymphoma kinase, Neoplasm Metastasis, Aged, 80 and over, Brain Neoplasms, General Medicine, Middle Aged, Protein-Tyrosine Kinases, anaplastic lymphoma kinase, 030220 oncology & carcinogenesis, Original Article, medicine.drug, medicine.medical_specialty, Drug-Related Side Effects and Adverse Reactions, Lactams, Lactams, Macrocyclic, Hypercholesterolemia, Subgroup analysis, 03 medical and health sciences, lorlatinib, Clinical Research, Proto-Oncogene Proteins, Internal medicine, ROS1, Carcinoma, Humans, Lung cancer, Protein Kinase Inhibitors, Aged, crizotinib, Crizotinib, business.industry, medicine.disease, Lorlatinib, 030104 developmental biology, Drug Resistance, Neoplasm, Mutation, Pyrazoles, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cafd98324b778f3492d5868e94a8541
https://doi.org/10.1111/cas.14576

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9

Arginine is a disease modifier for polyQ disease models that stabilizes polyQ protein conformation

المصدر: Brain. 143:1811-1825

مصطلحات موضوعية: Male, 0301 basic medicine, Protein Folding, Arginine, Protein Conformation, Mice, Inbred Strains, Protein aggregation, Protein Aggregation, Pathological, Mice, 03 medical and health sciences, 0302 clinical medicine, medicine, Animals, Spinocerebellar Ataxias, Caenorhabditis elegans, Dentatorubral-pallidoluysian atrophy, Chemistry, Neurodegeneration, medicine.disease, Cell biology, Disease Models, Animal, Spinal and bulbar muscular atrophy, Huntington Disease, 030104 developmental biology, Spinocerebellar ataxia, Heredodegenerative Disorders, Nervous System, Drosophila, Female, Protein folding, Neurology (clinical), Chemical chaperone, Peptides, 030217 neurology & neurosurgery, Molecular Chaperones

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd4f73ca15a62ebe41ff1064b654b1cf
https://doi.org/10.1093/brain/awaa115

10

Assessment of associations between clinical and immune microenvironmental factors and tumor mutation burden in resected nonsmall cell lung cancer by applying machine learning to whole‐slide images

المصدر: Cancer Medicine
Cancer Medicine, Vol 9, Iss 13, Pp 4864-4875 (2020)

مصطلحات موضوعية: 0301 basic medicine, Male, Cancer Research, Lung Neoplasms, Lymphocyte, computer.software_genre, B7-H1 Antigen, Machine Learning, 0302 clinical medicine, CEA, Carcinoma, Non-Small-Cell Lung, Tumor Microenvironment, Stage (cooking), Original Research, Aged, 80 and over, Smokers, FOXP3, Forkhead Transcription Factors, Middle Aged, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Primary tumor, medicine.anatomical_structure, Oncology, 030220 oncology & carcinogenesis, Carcinoma, Squamous Cell, Regression Analysis, Female, Cancer Prevention, Adult, Stromal cell, immune microenvironment, Adenocarcinoma, Machine learning, tumor mutation burden, lcsh:RC254-282, 03 medical and health sciences, Immune system, Lymphocytes, Tumor-Infiltrating, Antigens, Neoplasm, Exome Sequencing, medicine, Humans, Radiology, Nuclear Medicine and imaging, Pathological, Aged, Keratin-19, business.industry, whole‐slide imaging, Non-Smokers, medicine.disease, Carcinoembryonic Antigen, 030104 developmental biology, Mutation, Artificial intelligence, business, Ex-Smokers, computer, CD8, nonsmall cell lung cancer

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfe94d9a76522321b240ed7080e3f251
http://europepmc.org/articles/PMC7333844

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