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المؤلفون: José R. Franco, Olema Erphas, François Chappuis, Veerle Lejon, Elie A. Akl, Gemma Villanueva, Andreas K. Lindner, Leon Kazumba, Erick Mwamba, Jorge Seixas, Michael P. Barrett, Hanna Bergman, Augustin Kadima Ebeja, Gerardo Priotto, Pere P. Simarro
المصدر: The Lancet Infectious Diseases. 20:e38-e46
مصطلحات موضوعية: Adult, Male, 0301 basic medicine, medicine.medical_specialty, Eflornithine, Adolescent, Combination therapy, Trypanosoma brucei gambiense, 030231 tropical medicine, Antiprotozoal Agents, Disease, World Health Organization, Young Adult, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, medicine, Humans, African trypanosomiasis, Child, Nifurtimox, Intensive care medicine, Aged, Aged, 80 and over, medicine.diagnostic_test, business.industry, Lumbar puncture, Infant, Newborn, Infant, Middle Aged, medicine.disease, Trypanosomiasis, African, 030104 developmental biology, Infectious Diseases, chemistry, Nitroimidazoles, Child, Preschool, Practice Guidelines as Topic, Female, business, Trypanosomiasis, medicine.drug, Pentamidine, Fexinidazole
وصف الملف: application/pdf
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المؤلفون: Terry K. Smith, Peter E. Cockram, Michael P. Barrett, Emily A. Dickie
المساهمون: University of St Andrews. School of Biology, University of St Andrews. Biomedical Sciences Research Complex
المصدر: PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 14, Iss 12, p e0008928 (2020)مصطلحات موضوعية: 0301 basic medicine, Life Cycles, Transamination, RC955-962, Protozoology, 01 natural sciences, Biochemistry, chemistry.chemical_compound, Aromatic Amino Acids, Arctic medicine. Tropical medicine, Aromatic amino acids, Metabolites, African trypanosomiasis, Leishmania major, Amino Acids, chemistry.chemical_classification, Protozoans, biology, Molecular Structure, Organic Compounds, Tryptophan, Eukaryota, Esters, QR Microbiology, Chemistry, Infectious Diseases, Physical Sciences, Protozoan Life Cycles, Public aspects of medicine, RA1-1270, Research Article, RM, Trypanosoma, Cell Physiology, Cell Survival, Trypanosoma brucei brucei, Virulence, Trypanosoma brucei, Microbiology, 03 medical and health sciences, medicine, Trypanosoma Brucei, Humans, Organic Chemistry, Public Health, Environmental and Occupational Health, Chemical Compounds, Organisms, Biology and Life Sciences, Proteins, DAS, Metabolism, Cell Biology, Trypomastigotes, medicine.disease, biology.organism_classification, Parasitic Protozoans, RM Therapeutics. Pharmacology, QR, 0104 chemical sciences, Cell Metabolism, Amino Acid Metabolism, 010404 medicinal & biomolecular chemistry, 030104 developmental biology, chemistry, HeLa Cells, Trypanosoma Brucei Gambiense, Developmental Biology
وصف الملف: application/pdf
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المؤلفون: Angelica Hollunder Klippel, Elizabeth Bilsland, Sandro Roberto Valentini, Rafael M. Couñago, Mario H. Bengtson, Suelen Fernandes Silva, Andree da Silva Santiago, Katlin B. Massirer, Cleslei Fernando Zanelli, P.Z. Ramos
المساهمون: Universidade Estadual Paulista (Unesp), Universidade Estadual de Campinas (UNICAMP)
المصدر: Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
PLoS Neglected Tropical Diseases, Vol 14, Iss 10, p e0008762 (2020)
PLoS Neglected Tropical Diseasesمصطلحات موضوعية: 0301 basic medicine, Nematoda, RC955-962, Drug Evaluation, Preclinical, Protozoan Proteins, Yeast and Fungal Models, Biochemistry, Brugia malayi, chemistry.chemical_compound, 0302 clinical medicine, Arctic medicine. Tropical medicine, Deoxyhypusine synthase, Leishmania major, Brugia Malayi, Enzyme Inhibitors, Enzyme Chemistry, Protozoans, Anthelmintics, Oxidoreductases Acting on CH-NH Group Donors, Crystallography, biology, Physics, Biochemical Cofactors, Eukaryota, Helminth Proteins, Condensed Matter Physics, Enzymes, Infectious Diseases, Bioassays and Physiological Analysis, Experimental Organism Systems, Physical Sciences, Crystal Structure, Saccharomyces Cerevisiae, Public aspects of medicine, RA1-1270, EIF5A, Research Article, Trypanosoma, 030231 tropical medicine, Saccharomyces cerevisiae, Antiprotozoal Agents, Research and Analysis Methods, 03 medical and health sciences, Saccharomyces, Eukaryotic translation, Model Organisms, Brugia, Trypanosoma Brucei, Solid State Physics, Animals, Amino Acid Sequence, Gene, Enzyme Assays, Hypusine, Public Health, Environmental and Occupational Health, Organisms, Fungi, Biology and Life Sciences, Proteins, biology.organism_classification, Invertebrates, Yeast, Parasitic Protozoans, High-Throughput Screening Assays, 030104 developmental biology, chemistry, biology.protein, Animal Studies, Enzymology, Biochemical Analysis, Zoology, Sequence Alignment, Trypanosoma Brucei Gambiense
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5421839c45df0419889cf3653f751e91
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المؤلفون: Mechtilda Byamungu, Jennifer S. Lord, Glyn A. Vale, Harriet Auty, John W. Hargrove, Stephen J. Torr, David Hall, Furaha Mramba, Rachel S. Lea, Fiona K. Allan, Jessica K. Lingley, Edith Paxton, Liam J. Morrison
المصدر: PLoS Neglected Tropical Diseases, Vol 14, Iss 8, p e0008288 (2020)
PLoS Neglected Tropical Diseases
Lord, J, Lea, R S, Allan, F, Byamungu, M, Hall, D R, Lingley, J, Mramba, F, Paxton, E, Vale, G, Hargrove, J W, Morrison, L, Torr, S J & Auty, H K 2020, ' Assessing the effect of insecticide-treated cattle on tsetse abundance and trypanosome transmission at the wildlife-livestock interface in Serengeti, Tanzania ', PLoS Neglected Tropical Diseases . https://doi.org/10.1371/journal.pntd.0008288مصطلحات موضوعية: Trypanosoma brucei rhodesiense, 0301 basic medicine, trypanosomiasis, Insecticides, Veterinary medicine, tsetse, sleeping sickness, RC955-962, Wildlife, Polymerase Chain Reaction, Tanzania, 030308 mycology & parasitology, law.invention, chemistry.chemical_compound, 0302 clinical medicine, law, wc_705, Arctic medicine. Tropical medicine, Pyrethrins, Prevalence, African trypanosomiasis, Animal Management, Protozoans, 2. Zero hunger, 0303 health sciences, qx_4, Pyrethroid, biology, Eukaryota, Agriculture, Professions, Infectious Diseases, Transmission (mechanics), Agricultural Workers, Female, Livestock, Public aspects of medicine, RA1-1270, Agrochemicals, Research Article, Veterinary Medicine, Trypanosoma, S1, Veterinary parasitology, Tsetse Flies, 030231 tropical medicine, Cattle Diseases, Animals, Wild, wa_395, 03 medical and health sciences, wildlife-livestock interface, parasitic diseases, Trypanosoma Brucei, medicine, Animals, business.industry, Organisms, Public Health, Environmental and Occupational Health, Biology and Life Sciences, Models, Theoretical, Veterinary Parasitology, biology.organism_classification, medicine.disease, Parasitic Protozoans, Trypanosomiasis, African, 030104 developmental biology, chemistry, People and Places, Herd, Cattle, Parasitology, Veterinary Science, Livestock Care, Population Groupings, business, Zoology, Trypanosomiasis, Trypanosoma Brucei Gambiense
وصف الملف: application/pdf
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المؤلفون: Raphaël Labruère, Philippe M. Loiseau, Stéphanie Pethe, Elodie Jagu, Sébastien Pomel, Alba Diez-Martinez, Estelle Rascol
المصدر: European Journal of Medicinal Chemistry. 150:655-666
مصطلحات موضوعية: 0301 basic medicine, Spermidine, Stereochemistry, Trypanosoma brucei gambiense, Antiprotozoal Agents, Leishmania donovani, 010402 general chemistry, 01 natural sciences, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, Parasitic Sensitivity Tests, parasitic diseases, Drug Discovery, Biological evaluation, Pharmacology, chemistry.chemical_classification, Dose-Response Relationship, Drug, Molecular Structure, biology, Organic Chemistry, General Medicine, biology.organism_classification, 0104 chemical sciences, 030104 developmental biology, Enzyme, chemistry, Trypanothione reductase, Polyamine
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المؤلفون: Bruno Scherrer, Victor Kande Betu Ku Mesu, Crispin Lumbala, Olaf Valverde Mordt, Nathalie Strub-Wourgaft, Wilfried Mutombo Kalonji, Séverine Blesson, Willy Kuziena, Jean Pierre Fina Lubaki, Steven Lumeya Vuvu, Pathou Nganzobo Ngima, Augustin Kasongo Bonama, François Simon, Lewis Kaninda Badibabi, Jean Louis Lumaliza Solomo, Medard Ilunga, Sonja C. Bernhard, Francis Regongbenga Dama, Josué Amici Heradi, Guylain Mandula, Papy Kavunga Lukula, Clélia Bardonneau, Hélène Mahenzi Mbembo, Digas Ngolo Tete, Sophie Delhomme, Antoine Tarral
المصدر: The Lancet. 391:144-154
مصطلحات موضوعية: Adult, Male, 0301 basic medicine, medicine.medical_specialty, Combination therapy, Trypanosoma brucei gambiense, Population, Administration, Oral, Drug Administration Schedule, 03 medical and health sciences, chemistry.chemical_compound, Eflornithine, Internal medicine, medicine, Humans, African trypanosomiasis, Nifurtimox, education, education.field_of_study, business.industry, General Medicine, Middle Aged, medicine.disease, Trypanocidal Agents, Surgery, Regimen, Treatment Outcome, Trypanosomiasis, African, 030104 developmental biology, chemistry, Nitroimidazoles, Democratic Republic of the Congo, Drug Therapy, Combination, Female, business, Trypanosomiasis, medicine.drug, Fexinidazole
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المؤلفون: Daniel Ken Inaoka, Shigeharu Harada, Yasutoshi Kido, Kimitoshi Sakamoto, Paul A.M. Michels, Tomoo Shiba, Suzumi M. Tokuoka, Yoh-ichi Watanabe, Emmanuel Oluwadare Balogun, Kiyoshi Kita, Fuyuki Tokumasu
المصدر: Biochimica et Biophysica Acta (BBA) - General Subjects. 1861:2830-2842
مصطلحات موضوعية: Glycerol, 0301 basic medicine, Glycerol kinase, Protein Conformation, Trypanosoma brucei gambiense, Phosphatase, Biophysics, Biology, Crystallography, X-Ray, Biochemistry, Substrate Specificity, Phosphotransferase, 03 medical and health sciences, chemistry.chemical_compound, Adenosine Triphosphate, Glycerol Kinase, Animals, Humans, Transferase, Molecular Biology, Nitrobenzenes, Kinase, Autophosphorylation, Phosphoric Monoester Hydrolases, Adenosine Diphosphate, 030104 developmental biology, chemistry, Glycerophosphates, Phosphorylation, Adenosine triphosphate
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المؤلفون: Sabine Kuettel, Michele Tinti, Michael A. J. Ferguson, Alan R. Prescott, Maria Lucia S. Güther
المصدر: PLoS Neglected Tropical Diseases, Vol 15, Iss 2, p e0009132 (2021)
PLoS Neglected Tropical Diseasesمصطلحات موضوعية: 0301 basic medicine, Cell Membranes, RC955-962, Nucleotide sugar, Microbodies, Biochemistry, chemistry.chemical_compound, Fluorescence Microscopy, Mutase, Arctic medicine. Tropical medicine, Protozoans, Microscopy, biology, Nucleotides, Eukaryota, Light Microscopy, Peroxisome, 3. Good health, Infectious Diseases, Cellular Structures and Organelles, Public aspects of medicine, RA1-1270, Research Article, Immunofluorescence Microscopy, Trypanosoma, Trypanosoma brucei brucei, 030106 microbiology, Trypanosoma brucei, Biosynthesis, Research and Analysis Methods, Glycosome, 03 medical and health sciences, Organelle, Trypanosoma Brucei, Life Cycle Stages, Organisms, Public Health, Environmental and Occupational Health, Biology and Life Sciences, Membrane Proteins, Cell Biology, biology.organism_classification, Parasitic Protozoans, carbohydrates (lipids), 030104 developmental biology, chemistry, Sugars, Trypanosoma Brucei Gambiense
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المؤلفون: Alexandra G. Raftery, Saloum Jallow, Jean Rodgers, D. G. M. Sutton
المصدر: PLoS Neglected Tropical Diseases, Vol 13, Iss 3, p e0007175 (2019)
PLoS Neglected Tropical Diseasesمصطلحات موضوعية: 0301 basic medicine, Male, Disease, Abortion, Arsenicals, law.invention, chemistry.chemical_compound, Diminazene, Random Allocation, 0302 clinical medicine, Randomized controlled trial, law, Zoonoses, Medicine and Health Sciences, Prospective Studies, Asses, Protozoans, Mammals, education.field_of_study, Pharmaceutics, Triazines, lcsh:Public aspects of medicine, Eukaryota, Trypanocidal Agents, Phenanthridines, Infectious Diseases, Treatment Outcome, Vertebrates, Female, Gambia, Isometamidium chloride, medicine.drug, Research Article, medicine.medical_specialty, Trypanosoma, lcsh:Arctic medicine. Tropical medicine, lcsh:RC955-962, 030231 tropical medicine, Population, Equines, 03 medical and health sciences, Pharmacotherapy, Drug Therapy, Trypanosomiasis, Internal medicine, medicine, Trypanosoma Brucei, Parasitic Diseases, Animals, Horses, education, Protozoan Infections, business.industry, Public Health, Environmental and Occupational Health, Organisms, Biology and Life Sciences, lcsh:RA1-1270, Equidae, medicine.disease, Parasitic Protozoans, 030104 developmental biology, chemistry, Amniotes, Horse Diseases, business, Trypanosoma Brucei Gambiense
وصف الملف: application/pdf
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المؤلفون: Dana M. Klug, Francisco Gamarro, Rosario Diaz-Gonzalez, Guiomar Pérez-Moreno, Maria Santos Martinez-Martinez, Dolores González-Pacanowska, Lori Ferrins, Raquel García-Hernández, Michael P. Pollastri, Gloria Ceballos-Pérez, Verónica Gómez-Pérez, Pilar Manzano, Domingo I. Rojas-Barros, Conor R. Caffrey, Luis M. Ruiz-Pérez, Miguel Navarro
المساهمون: National Institute of Allergy and Infectious Diseases (US), Ministerio de Economía, Industria y Competitividad (España), Junta de Andalucía, Instituto de Salud Carlos III, Klug, Dana M. [0000-0002-8982-0640], Gamarro, Francisco [0000-0003-1347-3440], González-Pacanowska, D. [0000-0002-4303-5209], Navarro, M. [0000-0003-2301-2699], Pollastri, M.P. [0000-0001-9943-7197], Klug, Dana M., Gamarro, Francisco, González-Pacanowska, D., Navarro, M., Pollastri, M.P.
المصدر: PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 13, Iss 2, p e0007129 (2019)
Digital.CSIC. Repositorio Institucional del CSIC
instnameمصطلحات موضوعية: 0301 basic medicine, Kinase Inhibitors, Pharmacology, Toxicology, Pathology and Laboratory Medicine, Biochemistry, chemistry.chemical_compound, Mice, 0302 clinical medicine, Antibiotics, Zoonoses, Medicine and Health Sciences, African trypanosomiasis, Enzyme Inhibitors, ADME, Protozoans, Cytotoxicity Assay, Molecular Structure, Antimicrobials, lcsh:Public aspects of medicine, Drugs, Eukaryota, Trypanocidal Agents, 3. Good health, Infectious Diseases, Neglected tropical diseases, Female, Research Article, Neglected Tropical Diseases, Chagas disease, Trypanosoma, lcsh:Arctic medicine. Tropical medicine, lcsh:RC955-962, 030231 tropical medicine, Schistosomiasis, Biology, Sulfonamide, Microbiology, African Trypanosomiasis, 03 medical and health sciences, Structure-Activity Relationship, Pharmacokinetics, Trypanosomiasis, Microbial Control, medicine, Parasitic Diseases, Trypanosoma Brucei, Animals, Protein Kinase Inhibitors, Protozoan Infections, Toxicity, Isatin, Public Health, Environmental and Occupational Health, Organisms, Biology and Life Sciences, lcsh:RA1-1270, medicine.disease, Tropical Diseases, In vitro, Parasitic Protozoans, 030104 developmental biology, Trypanosomiasis, African, chemistry, Enzymology, Trypanosoma Brucei Gambiense
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