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المؤلفون: Julio Saez-Rodriguez, Graham R. Bignell, Euan A. Stronach, Beiyuan Fu, Angela Matchan, Fiona M. Behan, Emanuel Gonçalves, Ruby Banerjee, Elisabeth Chen, Ultan McDermott, Gabriele Picco, Fengtang Yang, Kosuke Yusa, Luz Garcia Alonso, Cyril H. Benes, David J. Dow, Adam Butler, Elizabeth Anderson, Francesco Iorio, Mathew J. Garnett
المصدر: Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Nature Communicationsمصطلحات موضوعية: 0301 basic medicine, BRD4, CRISPR-Cas systems, Carcinogenesis, Science, General Physics and Astronomy, Datasets as Topic, Antineoplastic Agents, 02 engineering and technology, Computational biology, Biology, medicine.disease_cause, General Biochemistry, Genetics and Molecular Biology, Article, Fusion gene, 03 medical and health sciences, Targeted therapies, Cell Line, Tumor, Neoplasms, ROS1, medicine, Biomarkers, Tumor, Cancer genomics, CRISPR, Humans, lcsh:Science, Gene, Early Detection of Cancer, Regulation of gene expression, Multidisciplinary, Sequence Analysis, RNA, Gene Expression Profiling, Cancer, High-Throughput Nucleotide Sequencing, Functional genomics, General Chemistry, Genomics, 021001 nanoscience & nanotechnology, medicine.disease, Gene Expression Regulation, Neoplastic, 030104 developmental biology, Drug Resistance, Neoplasm, Cancer cell, lcsh:Q, Gene Fusion, 0210 nano-technology
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المؤلفون: Florian Uhlitz, Bertram Klinger, Martina Klünemann, Julio Saez-Rodriguez, Sascha Sauer, Anja Sieber, Michael Schubert, Mathew J. Garnett, Nils Blüthgen
المصدر: Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Nature Communications
Nature Communications 9, 20 (2018). doi:10.1038/s41467-017-02391-6مصطلحات موضوعية: 0301 basic medicine, Science, General Physics and Astronomy, Gene Expression, Genomics, Computational biology, Biology, General Biochemistry, Genetics and Molecular Biology, Article, law.invention, 03 medical and health sciences, law, Cell Line, Tumor, Neoplasms, Gene expression, Humans, lcsh:Science, Gene, Multidisciplinary, HEK 293 cells, General Chemistry, 3. Good health, 030104 developmental biology, HEK293 Cells, Cell culture, Drug Resistance, Neoplasm, Mutation, Cancer gene, Suppressor, lcsh:Q, Technology Platforms, Pathway activity, Genes, Neoplasm
وصف الملف: application/pdf
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المؤلفون: Terezinha Souza, Jos C. S. Kleinjans, Julio Saez-Rodriguez, Laura I. Furlong, Danyel Jennen, Panuwat Trairatphisan, Janet Piñero
المساهمون: Toxicogenomics, RS: GROW - R1 - Prevention
المصدر: Frontiers in Genetics
Frontiers in genetics 9, 527 (2018). doi:10.3389/fgene.2018.00527
Recercat. Dipósit de la Recerca de Catalunya
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Frontiers in Genetics, Vol 9 (2018)
Frontiers in Genetics, 9:527. Frontiers Media S.A.مصطلحات موضوعية: 0301 basic medicine, lcsh:QH426-470, Text mining, TOXICOLOGY, Annotation, network biology, Computational biology, text mining, Biology, Interactome, LONG NONCODING RNAS, LRBA, 03 medical and health sciences, Bioinformàtica, TARGETS, ddc:570, Genetics, NETWORK, Gene, Transcription factor, Genetics (clinical), Original Research, MALAT1, Translational bioinformatics, Gene Annotation, IN-VITRO, CANCER, 3. Good health, EXPRESSION SIGNATURES, lcsh:Genetics, TRANSCRIPTION FACTORS, 030104 developmental biology, TOXICOGENOMICS, annotation, DNA-DAMAGE, Molecular Medicine, Network biology, gene ontology, translational bioinformatics, Gene ontology, DILI, Toxicogenomics
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b60f7643e64c4d890261b9c6ba7b0216
https://doi.org/10.3389/fgene.2018.00527 -
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المؤلفون: Francesco Iorio, Mathew J. Garnett, Fiona M. Behan, Piers Wilkinson, Rizwan Ansari, Charlotte M. Beaver, Elisabeth Chen, Rebecca Shepherd, Kosuke Yusa, Julio Saez-Rodriguez, Euan A. Stronach, Rachel Pooley, Adam Butler, Sarah Harper, Shriram G. Bhosle, Emanuel Gonçalves
المصدر: BMC Genomics, Vol 19, Iss 1, Pp 1-16 (2018)
BMC genomics 19(1), 604 (2018). doi:10.1186/s12864-018-4989-y
BMC Genomicsمصطلحات موضوعية: 0301 basic medicine, DNA Copy Number Variations, lcsh:QH426-470, lcsh:Biotechnology, Computational biology, Biology, Genome, Gene Knockout Techniques, 03 medical and health sciences, 610 Medical sciences Medicine, 0302 clinical medicine, Genome editing, Cell Line, Tumor, Neoplasms, lcsh:TP248.13-248.65, False positive paradox, Genetics, Humans, CRISPR, Copy-number variation, Gene, 030304 developmental biology, Subgenomic mRNA, Cancer, 0303 health sciences, Genes, Essential, Genome, Human, Gene copy number, Methodology Article, Gene Amplification, RNA, Sequence Analysis, DNA, Genetic screens, Fold change, High-Throughput Screening Assays, lcsh:Genetics, 030104 developmental biology, Gene Targeting, Bias correction, CRISPR-Cas Systems, CRISPR-Cas9, DNA microarray, Software, 030217 neurology & neurosurgery, Biotechnology, Genetic screen
وصف الملف: application/pdf
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المؤلفون: Bence Szalai, Christian H. Holland, Julio Saez-Rodriguez
المصدر: Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms. 1863:194431
مصطلحات موضوعية: 0301 basic medicine, ved/biology.organism_classification_rank.species, Biophysics, Computational biology, Biology, Biochemistry, Conserved sequence, Mice, 03 medical and health sciences, 0302 clinical medicine, Structural Biology, Gene expression, Genetics, Animals, Humans, Disease, Model organism, Molecular Biology, Gene, Transcription factor, ved/biology, business.industry, Gene Expression Profiling, Usability, Genomics, Benchmarking, 030104 developmental biology, Gene Expression Regulation, business, Pathway activity, Functional genomics, 030217 neurology & neurosurgery, Transcription Factors
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المؤلفون: Luz Garcia-Alonso, Jonathan S. Brammeld, Julio Saez-Rodriguez, Inigo Martincorena, Francesco Iorio, Ultan McDermott, David R. Willé
المصدر: Scientific reports 8, 6713 (2018). doi:10.1038/s41598-018-25076-6
Scientific Reports, Vol 8, Iss 1, Pp 1-16 (2018)
Scientific Reportsمصطلحات موضوعية: 0301 basic medicine, Somatic cell, lcsh:Medicine, Computational biology, Biology, Genome, Article, Biological pathway, 03 medical and health sciences, 0302 clinical medicine, Neoplasms, Selective advantage, medicine, Humans, Gene Regulatory Networks, lcsh:Science, Gene, 030304 developmental biology, Regulation of gene expression, 0303 health sciences, Multidisciplinary, Genome, Human, lcsh:R, Cancer, Genomics, Models, Theoretical, medicine.disease, Human genetics, Neoplasm Proteins, Gene Expression Regulation, Neoplastic, R package, Open source, 030104 developmental biology, 030220 oncology & carcinogenesis, Mutation, Cancer gene, lcsh:Q, Signal Transduction
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c376d931a04b7e6d17123a64a31bf4f3
https://publications.rwth-aachen.de/record/757419 -
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المؤلفون: Pedro Beltrao, Julio Saez-Rodriguez, Claudia Hernandez-Armenta, David Ochoa, Emanuel Gonçalves
المصدر: Bioinformatics 33(12), 1845-1851 (2017). doi:10.1093/bioinformatics/btx082
Bioinformatics, 33 (12)
Bioinformaticsمصطلحات موضوعية: Proteomics, 0301 basic medicine, Statistics and Probability, Wilcoxon signed-rank test, Computer science, In silico, Inference, Computational biology, Biology, Kolmogorov–Smirnov test, Biochemistry, Set (abstract data type), symbols.namesake, 03 medical and health sciences, 0302 clinical medicine, Statistics, Humans, Computer Simulation, Kinase activity, Molecular Biology, Gene, Kinase, Systems Biology, Phosphotransferases, Substrate (chemistry), Gold standard (test), Phosphoproteins, Original Papers, Weighting, Computer Science Applications, Computational Mathematics, 030104 developmental biology, Computational Theory and Mathematics, symbols, Phosphorylation, Software, 030217 neurology & neurosurgery, Signal Transduction
وصف الملف: application/application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36c93aa29df61929554c4169bdc699ee
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المؤلفون: Mehmet Gönen, Barbara A. Weir, Glenn S. Cowley, Francisca Vazquez, Yuanfang Guan, Alok Jaiswal, Masayuki Karasuyama, Vladislav Uzunangelov, Tao Wang, Aviad Tsherniak, Sara Howell, Daniel Marbach, Bruce Hoff, Thea C. Norman, Antti Airola, Adrian Bivol, Kerstin Bunte, Daniel Carlin, Sahil Chopra, Alden Deran, Kyle Ellrott, Peddinti Gopalacharyulu, Kiley Graim, Samuel Kaski, Suleiman A. Khan, Yulia Newton, Sam Ng, Tapio Pahikkala, Evan Paull, Artem Sokolov, Hao Tang, Jing Tang, Krister Wennerberg, Yang Xie, Xiaowei Zhan, Fan Zhu, Tero Aittokallio, Hiroshi Mamitsuka, Joshua M. Stuart, Jesse S. Boehm, David E. Root, Guanghua Xiao, Gustavo Stolovitzky, William C. Hahn, Adam A. Margolin, Bahman Afsari, Yu-Chuan Chang, Tenghui Chen, Zechen Chong, Haitham Elmarakeby, Elana J. Fertig, Emanuel Gonçalves, Pinghua Gong, Christoph Hafemeister, Lenwood Heath, Łukasz Kędziorski, Niraj Khemka, Erh-kan King, Mario Lauria, Mark Liu, Daniel Machado, Mateusz Mazurkiewicz, Michael P. Menden, Szymon Migacz, Zhi Nie, Paurush Praveen, Corrado Priami, Simone Rizzetto, Miguel Rocha, Cameron Rudd, Witold R. Rudnicki, Julio Saez-Rodriguez, Lei Song, Duanchen Sun, Bence Szalai, Difei Wang, Ling-yun Wu, Jieping Ye, Yuting Ye, Wanding Zhou
المصدر: Cell Systems. 5:497-e3
مصطلحات موضوعية: 0301 basic medicine, Histology, Gene Expression, Computational biology, Biology, Data type, Article, cancer genomics, community challenge, crowdsourcing, functional screen, machine learning, oncogene, 2734, Cell Biology, Pathology and Forensic Medicine, 03 medical and health sciences, Open research, Cell Line, Tumor, Humans, RNA, Small Interfering, Gene, ta217, ta113, Genetics, Genes, Essential, ta1184, Genomics, ta3122, 030104 developmental biology, Community resource, Identification (biology), Cancer cell lines, Algorithms, Genetic screen
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