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المؤلفون: Fabio Mammano, Veronica Zorzi, Gaia Ziraldo, Giovanna Morello, Anna Maria Salvatore, Maria Guarnaccia, Anna Rita Fetoni, Gaetano Paludetti, Denis Cuccaro, Guy Van Camp, Giulia Gentile, Fabiola Paciello, Marco Brumat, Antonio Gianmaria Spampinato, Erik Fransen, Giulia Crispino, Chiara Peres, Sebastiano Cavallaro, Ferdinando Scavizzi, Gabriella Tognola, Marcello Raspa, Paolo Gasparini, Giorgia Girotto
المساهمون: Fetoni, Anna Rita, Zorzi, Veronica, Paciello, Fabiola, Ziraldo, Gaia, Peres, Chiara, Raspa, Marcello, Scavizzi, Ferdinando, Salvatore, Anna Maria, Crispino, Giulia, Tognola, Gabriella, Gentile, Giulia, Spampinato, Antonio Gianmaria, Cuccaro, Deni, Guarnaccia, Maria, Morello, Giovanna, Van Camp, Guy, Fransen, Erik, Brumat, Marco, Girotto, Giorgia, Paludetti, Gaetano, Gasparini, Paolo, Cavallaro, Sebastiano, Mammano, Fabio, Fetoni, Ar, Zorzi, V, Paciello, F, Ziraldo, G, Peres, C, Raspa, M, Scavizzi, F, Salvatore, Alba Maria Rita, Crispino, G, Tognola, G, Gentile, Giuseppe, Spampinato, Ag, Cuccaro, D, Guarnaccia, M, Morello, G, Van Camp, G, Fransen, E, Brumat, M, Girotto, G, Paludetti, G, Gasparini, P, Cavallaro, S, Mammano, F.
المصدر: Redox Biology, Vol 19, Iss, Pp 301-317 (2018)
RedoxBiology 19 (2018): 301–317. doi:10.1016/j.redox.2018.08.002
info:cnr-pdr/source/autori:Anna Rita Fetoni; Veronica Zorzi; Fabiola Paciello; Gaia Ziraldo; Chiara Peres; Marcello Raspa; Ferdinando Scavizzi; Anna Maria Salvatore; Giulia Crispino; Gabriella Tognola; Giulia Gentile; Antonio Gianmaria Spampinato; Denis Cuccaro; Maria Guarnaccia; Giovanna Morello; Guy Van Camp; Erik Fransen; Marco Brumat; Giorgia Girotto; Gaetano Paludetti; Paolo Gasparini; Sebastiano Cavallaro; Fabio Mammano/titolo:Cx26 partial loss causes accelerated presbycusis by redox imbalance and dysregulation of Nfr2 pathway/doi:10.1016%2Fj.redox.2018.08.002/rivista:RedoxBiology/anno:2018/pagina_da:301/pagina_a:317/intervallo_pagine:301–317/volume:19
Redox Biologyمصطلحات موضوعية: Male, 0301 basic medicine, Clinical Biochemistry, Connexin, Presbycusis, Apoptosis, Cochlear duct, Inbred C57BL, Hair cells, Mouse models, medicine.disease_cause, Biochemistry, Mice, lcsh:QH301-705.5, Regulation of gene expression, lcsh:R5-920, Chemistry, Cell biology, Connexin 26, medicine.anatomical_structure, Age-related hearing lo, Settore MED/32 - AUDIOLOGIA, Female, Hair cell, medicine.symptom, Signal transduction, lcsh:Medicine (General), Spiral ganglion neurons, Oxidation-Reduction, Research Paper, Signal Transduction, Age-related hearing loss, Genome-wide association study, Animals, Gene Deletion, Mice, Inbred C57BL, NF-E2-Related Factor 2, Organic Chemistry, Hearing loss, Settore BIO/09 - FISIOLOGIA, Mouse model, PRKCE Gene, 03 medical and health sciences, otorhinolaryngologic diseases, medicine, Biology, medicine.disease, 030104 developmental biology, lcsh:Biology (General), Oxidative stress
وصف الملف: pdf
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المؤلفون: Viola Donati, Francesco Zonta, Damiano Buratto, Fabio Mammano
المصدر: Biochimica et biophysica acta. Molecular basis of disease 1867 (2021). doi:10.1016/j.bbadis.2020.166047
info:cnr-pdr/source/autori:Buratto, Damiano; Donati, Viola; Zonta, Francesco; Mammano, Fabio/titolo:Harnessing the therapeutic potential of antibodies targeting connexin hemichannels/doi:10.1016%2Fj.bbadis.2020.166047/rivista:Biochimica et biophysica acta. Molecular basis of disease/anno:2021/pagina_da:/pagina_a:/intervallo_pagine:/volume:1867مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, medicine.drug_class, Connexin, Monoclonal antibody, Epitope, Antibodies, Connexins, 03 medical and health sciences, 0302 clinical medicine, Antineoplastic Agents, Immunological, Neoplasms, Drug Discovery, medicine, Animals, Humans, Molecular Biology, Cancer, Inflammation, biology, Point mutation, Rare diseases, Cell biology, 030104 developmental biology, antibody drug discovery, cancer, inflammation, rare diseases, Membrane protein, Polyclonal antibodies, Connexin 43, biology.protein, Molecular Medicine, Antibody, 030217 neurology & neurosurgery, Function (biology), Antibody drug discovery
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المؤلفون: Yu Li, Flavia Mazzarda, Lili Liu, Damiano Buratto, Francesco Zonta, Richard A. Lerner, Fabio Mammano, Marcello Raspa, Francesco Chiani, Youjun Chu, Gaia Ziraldo, Min Qiang, Ferdinando Scavizzi, Xiaojie Shi, Yaru Shi, Yuanyuan Kuang, Anna Maria Salvatore, Chiara Nardin, Guang Yang, Veronica Zorzi, Chiara Peres
المصدر: EBioMedicine
مصطلحات موضوعية: Keratinocytes, 0301 basic medicine, Cell physiology, Cell, Connexin, Antibodies, Connexins, General Biochemistry, Genetics and Molecular Biology, Antibody drug discovery, ATP, Calcium, Epidermis, Genodermatosis, Sebocytes, Mice, 03 medical and health sciences, Adenosine Triphosphate, 0302 clinical medicine, Ectodermal Dysplasia, In vivo, Connexin 30, medicine, Animals, Humans, Cell Proliferation, biology, business.industry, Wild type, Gap Junctions, General Medicine, In vitro, Disease Models, Animal, HaCaT, 030104 developmental biology, medicine.anatomical_structure, Gene Expression Regulation, 030220 oncology & carcinogenesis, Mutation, Commentary, biology.protein, Cancer research, Antibody, business
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5a79dd8ad793aeabb5d22c5e0801622
http://hdl.handle.net/11577/3346805 -
4Ca2+ signaling, apoptosis and autophagy in the developing cochlea: Milestones to hearing acquisition
المؤلفون: Fabio Mammano, Mario Bortolozzi
المصدر: Cell Calcium. 70:117-126
مصطلحات موضوعية: 0301 basic medicine, Physiology, Protein subunit, Lesser epithelial ridge, Morphogenesis, Connexin, Caspase 3, Development, Deafness, Biology, Mouse models, Greater epithelial ridge, Connexins, Inner hair cells, 03 medical and health sciences, otorhinolaryngologic diseases, Ca2+waves, Molecular Biology, Cochlea, Calcium signaling, Peripheral auditory system, Outer hair cells, Autophagy, IP3, Gap junction, Cell Biology, Anatomy, Mitochondria, ATP, 030104 developmental biology, Caspase-3, Peripheral auditory system, Development, Morphogenesis, Caspase-3, Mitochondria, Greater epithelial ridge, Lesser epithelial ridge, Ca2+waves, ATP, IP3, Spiral ganglion neurons, Inner hair cells, Outer hair cells, Connexins, Deafness, Mouse models, Spiral ganglion neurons, Neuroscience
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المؤلفون: John A. Chiorini, Matteo Campioni, Veronica Zorzi, Giulia Crispino, Fabian Galindo Ramirez, Giovanni Di Pasquale, Fabio Mammano, Mark Praetorius
المصدر: Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Scientific reports (Nature Publishing Group) 7 (2017): 6567–6580. doi:10.1038/s41598-017-06759-y
info:cnr-pdr/source/autori:Crispino, Giulia; Galindo Ramirez, Fabian; Campioni, Matteo; Zorzi, Veronica; Praetorius, Mark; Di Pasquale, Giovanni; Chiorini, John A.; Mammano, Fabio/titolo:In vivo genetic manipulation of inner ear connexin expression by bovine adeno-associated viral vectors/doi:10.1038%2Fs41598-017-06759-y/rivista:Scientific reports (Nature Publishing Group)/anno:2017/pagina_da:6567/pagina_a:6580/intervallo_pagine:6567–6580/volume:7
Scientific Reportsمصطلحات موضوعية: Male, 0301 basic medicine, HEARING IMPAIRMENT, Connexin, OUTER HAIR CELL, Deafness, Connexins, Mice, Parvovirinae, Mice, Knockout, Multidisciplinary, Anatomy, Dependovirus, Cochlea, Cell biology, Connexin 26, medicine.anatomical_structure, Medicine, Female, GUINEA-PIG COCHLEA, MOUSE COCHLEA, STRIA VASCULARIS, RAT COCHLEA, POSTNATAL-DEVELOPMENT, DNA RECOMBINATION, SURGICAL APPROACH, SUPPORTING CELLS, Endocochlear potential, Science, Genetic Vectors, Genetic transduction, Cre recombinase, Biology, Article, Viral vector, 03 medical and health sciences, medicine, otorhinolaryngologic diseases, Animals, Inner ear, Integrases, Genetic Therapy, Mice, Inbred C57BL, 030104 developmental biology, Organ of Corti, Ear, Inner, Cattle, sense organs
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المؤلفون: Gaia Ziraldo, Damiano Buratto, Yuanyuan Kuang, Liang Xu, Andrea Carrer, Chiara Nardin, Francesco Chiani, Anna Maria Salvatore, Gaetano Paludetti, Richard A. Lerner, Guang Yang, Francesco Zonta, Fabio Mammano
المصدر: Frontiers in Physiology
Frontiers in physiology 10 (2019): 1–14. doi:10.3389/fphys.2019.00392
info:cnr-pdr/source/autori:Ziraldo, Gaia; Buratto, Damiano; Kuang, Yuanyuan; Xu, Liang; Carrer, Andrea; Nardin, Chiara; Chiani, Francesco; Salvatore, Anna Maria; Paludetti, Gaetano; Lerner, Richard A.; Yang, Guang; Zonta, Francesco; Mammano, Fabio/titolo:A Human-Derived Monoclonal Antibody Targeting Extracellular Connexin Domain Selectively Modulates Hemichannel Function/doi:10.3389%2Ffphys.2019.00392/rivista:Frontiers in physiology/anno:2019/pagina_da:1/pagina_a:14/intervallo_pagine:1–14/volume:10
Frontiers in Physiology, Vol 10 (2019)مصطلحات موضوعية: 0301 basic medicine, Physiology, Connexin, patch clamp, lcsh:Physiology, Connexon, 03 medical and health sciences, 0302 clinical medicine, connexin hemichannels, Physiology (medical), Extracellular, Patch clamp, education, Original Research, education.field_of_study, Settore BIO/11 - BIOLOGIA MOLECOLARE, lcsh:QP1-981, Chemistry, Wild type, molecular dynamics, phage display libraries, rare diseases, therapeutic monoclonal antibodies, Pannexin, In vitro, Cell biology, 030104 developmental biology, Connexin 32, 030217 neurology & neurosurgery
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7556e8e60c014af59bfc5c329d114d3c
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المؤلفون: Francesco Zonta, Damiano Buratto, Giulia Crispino, Andrea Carrer, Francesca Bruno, Guang Yang, Fabio Mammano, Sergio Pantano
المصدر: Frontiers in Molecular Neuroscience, Vol 11 (2018)
Frontiers in molecular neuroscience 11 (2018): 1–12. doi:10.3389/fnmol.2018.00170
info:cnr-pdr/source/autori:Zonta, Francesco; Buratto, Damiano; Crispino, Giulia; Carrer, Andrea; Bruno, Francesca; Yang, Guang; Mammano, Fabio; Pantano, Sergio/titolo:Cues to Opening Mechanisms From in Silico Electric Field Excitation of Cx26 Hemichannel and in Vitro Mutagenesis Studies in HeLa Transfectans/doi:10.3389%2Ffnmol.2018.00170/rivista:Frontiers in molecular neuroscience/anno:2018/pagina_da:1/pagina_a:12/intervallo_pagine:1–12/volume:11
Frontiers in Molecular Neuroscienceمصطلحات موضوعية: 0301 basic medicine, Conformational change, connexin, Connexin, coarse grained simulations, lcsh:RC321-571, Cx26, 03 medical and health sciences, Cellular and Molecular Neuroscience, conformational change, Patch clamp, SIRAH force field, electrophysiology, gap junction hemichannels, Molecular Biology, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, Original Research, Chemistry, Mutagenesis, Gap junction, Transmembrane domain, Electrophysiology, 030104 developmental biology, Cytoplasm, Biophysics, Neuroscience
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المؤلفون: Mario Bortolozzi, Fabio Mammano
المصدر: Neuroscience letters
663 (2018): 18–24. doi:10.1016/j.neulet.2017.09.059
info:cnr-pdr/source/autori:Bortolozzi, Mario; Mammano, Fabio/titolo:PMCA2 pump mutations and hereditary deafness/doi:10.1016%2Fj.neulet.2017.09.059/rivista:Neuroscience letters (Print)/anno:2018/pagina_da:18/pagina_a:24/intervallo_pagine:18–24/volume:663مصطلحات موضوعية: 0301 basic medicine, Mechanotransduction, Hearing Loss, Sensorineural, Cell, Ca2+ homeostasis, Hair cells, Deafness, Mouse models, Ca2+ homeostasis, Mechanotransduction, Stereocilia, Deafness, Hair cells, Mouse models, Stereocilia, Plasma Membrane Calcium-Transporting ATPases, 03 medical and health sciences, otorhinolaryngologic diseases, medicine, Animals, Humans, Protein Isoforms, Inner ear, Stcreocilia, Hair Cells, Auditory, Inner, Chemistry, General Neuroscience, Genetic Diseases, Inborn, Depolarization, Cell biology, 030104 developmental biology, medicine.anatomical_structure, Cytoplasm, Organ of Corti, Mutation, sense organs, Hair cell, Homeostasis
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2796ec2ea478fff4d7a1e81ede20beab
http://hdl.handle.net/11577/3257506 -
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المؤلفون: Liang Xu, Andrea Carrer, Francesco Zonta, Zhihu Qu, Peixiang Ma, Sheng Li, Federico Ceriani, Damiano Buratto, Giulia Crispino, Veronica Zorzi, Gaia Ziraldo, Francesca Bruno, Chiara Nardin, Chiara Peres, Flavia Mazzarda, Anna M. Salvatore, Marcello Raspa, Ferdinando Scavizzi, Youjun Chu, Sichun Xie, Xuemei Yang, Jun Liao, Xiao Liu, Wei Wang, Shanshan Wang, Guang Yang, Richard A. Lerner, Fabio Mammano
المصدر: Frontiers in Molecular Neuroscience, Vol 10 (2017)
Frontiers in molecular neuroscience 10 (2017): 298–317. doi:10.3389/fnmol.2017.00298
info:cnr-pdr/source/autori:Xu, Liang; Carrer, Andrea; Zonta, Francesco; Qu, Zhihu; Ma, Peixiang; Li, Sheng; Ceriani, Federico; Buratto, Damiano; Crispino, Giulia; Zorzi, Veronica; Ziraldo, Gaia; Bruno, Francesca; Nardin, Chiara; Peres, Chiara; Mazzarda, Flavia; Salvatore, Anna M.; Raspa, Marcello; Scavizzi, Ferdinando; Chu, Youjun; Xie, Sichun; Yang, Xuemei; Liao, Jun; Liu, Xiao; Wang, Wei; Wang, Shanshan; Yang, Guang; Lerner, Richard A.; Mammano, Fabio/titolo:Design and Characterization of a Human Monoclonal Antibody that Modulates Mutant Connexin 26 Hemichannels Implicated in Deafness and Skin Disorders/doi:10.3389%2Ffnmol.2017.00298/rivista:Frontiers in molecular neuroscience/anno:2017/pagina_da:298/pagina_a:317/intervallo_pagine:298–317/volume:10
Frontiers in Molecular Neuroscienceمصطلحات موضوعية: 0301 basic medicine, keratinocytes, Phage display, medicine.drug_class, cochlea, Connexin, antibody library, Biology, Monoclonal antibody, syndromic autosomal hereditary deafness, Connexon, Epitope, lcsh:RC321-571, 03 medical and health sciences, Cellular and Molecular Neuroscience, medicine, otorhinolaryngologic diseases, Molecular Biology, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, Original Research, antibody structure, connexins, epitope identification, Gap junction, Molecular biology, 3. Good health, Cell biology, 030104 developmental biology, Mechanism of action, biology.protein, sense organs, medicine.symptom, Antibody, Neuroscience
وصف الملف: application/pdf
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المؤلفون: Veronica Zorzi, Fabiola Paciello, Gaia Ziraldo, Chiara Peres, Flavia Mazzarda, Chiara Nardin, Miriam Pasquini, Francesco Chiani, Marcello Raspa, Ferdinando Scavizzi, Andrea Carrer, Giulia Crispino, Catalin D. Ciubotaru, Hannah Monyer, Anna R. Fetoni, Anna M. Salvatore, Fabio Mammano
المساهمون: Zorzi, Veronica, Paciello, Fabiola, Ziraldo, Gaia, Peres, Chiara, Mazzarda, Flavia, Nardin, Chiara, Pasquini, Miriam, Chiani, Francesco, Raspa, Marcello, Scavizzi, Ferdinando, Carrer, Andrea, Crispino, Giulia, Ciubotaru, Catalin D., Monyer, Hannah, Fetoni, Anna R., Salvatore, Anna M., Mammano, Fabio
المصدر: Frontiers in Molecular Neuroscience, Vol 10 (2017)
Frontiers in molecular neuroscience 10 (2017). doi:10.3389/fnmol.2017.00379
info:cnr-pdr/source/autori:Zorzi, Veronica; Paciello, Fabiola; Ziraldo, Gaia; Peres, Chiara; Mazzarda, Flavia; Nardin, Chiara; Pasquini, Miriam; Chiani, Francesco; Raspa, Marcello; Scavizzi, Ferdinando; Carrer, Andrea; Crispino, Giulia; Ciubotaru, Catalin D.; Monyer, Hannah; Fetoni, Anna R.; Salvatore, Anna M.; Mammano, Fabio/titolo:Mouse Panx1 Is Dispensable for Hearing Acquisition and Auditory Function/doi:10.3389%2Ffnmol.2017.00379/rivista:Frontiers in molecular neuroscience/anno:2017/pagina_da:/pagina_a:/intervallo_pagine:/volume:10
Frontiers in Molecular Neuroscienceمصطلحات موضوعية: 0301 basic medicine, Cochlear amplifier, medicine.medical_specialty, cochlea, pannexins, connexins, hair cells, non-sensory cells, auditory brainstem responses, distortion product otoacoustic emissions, hair cells, Settore BIO/09 - FISIOLOGIA, Otoacoustic emission, Connexin, Audiology, Biology, Pannexin, lcsh:RC321-571, 03 medical and health sciences, Cellular and Molecular Neuroscience, cochlea, pannexins, connexins, non-sensory cells, auditory brainstem responses, distortion product otoacoustic emissions, medicine, otorhinolaryngologic diseases, Auditory brainstem responses, Cochlea, Connexins, Distortion product otoacoustic emissions, Hair cells, Non-sensory cells, Pannexins, Molecular Biology, Inner ear, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, Original Research, Distortion product otoacoustic emission, Non-sensory cell, Auditory brainstem response, 030104 developmental biology, medicine.anatomical_structure, Organ of Corti, Hair cell, sense organs, Neuroscience
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e8dcbc7e28b0efdad06efeae315b37c
http://hdl.handle.net/11588/871873
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