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المؤلفون: Johan Auwerx, Daniel A. Peterson, Robert W. Williams, Autumn M. McKnite, Evan G. Williams, Maria Elisa Perez-Muñoz, Daniel C. Ciobanu
المصدر: PLoS ONE
PLOS ONE
PLoS ONE, Vol 14, Iss 10, p e0224100 (2019)مصطلحات موضوعية: 0301 basic medicine, Male, Gastrointestinal Microbiome/genetics, Biochemistry, Fats, Cecum, Mice, 0302 clinical medicine, Medicine and Health Sciences, Metabolites, Bifidobacterium, 2. Zero hunger, Genetics, Multidisciplinary, biology, Microbial Genetics, Genomics, Bifidobacterium/classification/physiology, Phenotype, Lipids, medicine.anatomical_structure, Liver, Cecum/microbiology, Medical Microbiology, Mice, Inbred DBA, Medicine, Female, Genetics & genetic processes [F10] [Life sciences], Anatomy, Génétique & processus génétiques [F10] [Sciences du vivant], Research Article, Liver/metabolism, Firmicutes, Science, Quantitative Trait Loci, Microbial Genomics, Quantitative trait locus, Diet, High-Fat, Microbiology, Actinobacteria, 03 medical and health sciences, medicine, Diet, High-Fat/adverse effects, Animals, Microbiome, Obesity, Nutrition, gut microbiota, Bacteria, Gut Bacteria, Body Weight, Organisms, Biology and Life Sciences, biology.organism_classification, Obesity/etiology/metabolism/pathology, Diet, Gastrointestinal Microbiome, Gastrointestinal Tract, Mice, Inbred C57BL, 030104 developmental biology, Metabolism, Genetics, Population, Genetic Loci, Microbial genetics, Digestive System, 030217 neurology & neurosurgery, iga
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المؤلفون: Jessy Cartier, Timothy J. Kendall, Amanda J. Drake, Raffaele Ottaviano, Marcus J. Lyall, John P. Thomson, Richard R. Meehan
المصدر: Lyall, M, Thomson, J, Cartier, J, Ottaviano, R, Kendall, T, Meehan, R & Drake, A 2019, ' Non-alcoholic fatty liver disease (NAFLD) is associated with dynamic changes in DNA hydroxymethylation ', Epigenetics, vol. 15, no. 1-2, pp. 61-71 . https://doi.org/10.1080/15592294.2019.1649527, https://doi.org/10.1080/15592294.2019.1649527
Epigeneticsمصطلحات موضوعية: 0301 basic medicine, Liver/metabolism, Male, Cancer Research, medicine.medical_specialty, Population, Biology, Diet, High-Fat, 5-Methylcytosine/analogs & derivatives, Pathogenesis, 03 medical and health sciences, Liver disease, Mice, 0302 clinical medicine, Insulin resistance, Non-alcoholic Fatty Liver Disease, Internal medicine, NAFLD, medicine, steatosis, Diet, High-Fat/adverse effects, Animals, Obesity, education, Molecular Biology, education.field_of_study, Non-alcoholic Fatty Liver Disease/etiology, Fatty liver, hydroxymethylation, DNA Methylation, medicine.disease, 3. Good health, Mice, Inbred C57BL, 030104 developmental biology, Endocrinology, Phenotype, Liver, 030220 oncology & carcinogenesis, DNA methylation, 5-Methylcytosine, Biomarker (medicine), methylation, Steatosis, Transcriptome, Research Paper
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ad125519dcfb3ee8ba4340d83a21c78
https://hdl.handle.net/20.500.11820/6dafbbff-acd0-4c8f-b9dd-8734e51c4d11 -
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المؤلفون: Jérémy Cros, Virgile Lecoultre, Bertrand Pouymayou, Anna Surowska, Chris Boesch, Léonie Egli, Robin Rosset, Anne-Sophie Marques, Roland Kreis, Vanessa Campos, Luc Tappy, Philippe Schneiter, P. Jegatheesan
المصدر: Nutrients
Volume 11
Issue 1
Nutrients, vol. 11, no. 1
Surowska, Anna; Jegatheesan, Prasanthi; Campos, Vanessa; Marques, Anne-Sophie; Egli, Léonie; Cros, Jérémy; Rosset, Robin; Lecoultre, Virgile; Kreis, Roland; Boesch, Christoph Hans; Pouymayou, Bertrand Michel Marie; Kreis, Roland; Tappy, Luc (2019). Effects of Dietary Protein and Fat Content on Intrahepatocellular and Intramyocellular Lipids during a 6-Day Hypercaloric, High Sucrose Diet: A Randomized Controlled Trial in Normal Weight Healthy Subjects. Nutrients, 11(1) Molecular Diversity Preservation International MDPI 10.3390/nu11010209 <http://dx.doi.org/10.3390/nu11010209>
Nutrients, Vol 11, Iss 1, p 209 (2019)مصطلحات موضوعية: Male, dietary protein content, Low protein, Sucrose, 030204 cardiovascular system & hematology, plasma triglyceride, law.invention, chemistry.chemical_compound, 0302 clinical medicine, Randomized controlled trial, law, Dietary Sucrose, energy expenditure, Adipose Tissue/metabolism, Adiposity/drug effects, Adult, Cross-Over Studies, Diet, Diet, High-Fat/adverse effects, Diet, Protein-Restricted/adverse effects, Dietary Fats/administration & dosage, Dietary Fats/metabolism, Dietary Fats/pharmacology, Dietary Proteins/administration & dosage, Dietary Proteins/pharmacology, Dietary Sucrose/adverse effects, Energy Intake, Feeding Behavior, Female, Healthy Volunteers, Humans, Lipid Metabolism/drug effects, Lipids, Liver/cytology, Liver/drug effects, Liver/metabolism, Muscle, Skeletal/cytology, Muscle, Skeletal/drug effects, Muscle, Skeletal/metabolism, Young Adult, dietary fat content, hepatic steatosis, intrahepatocellular lipids, intramyocellular lipids, sucrose overfeeding, Adiposity, Nutrition and Dietetics, Chemistry, Healthy subjects, 3. Good health, Adipose Tissue, Liver, Analysis of variance, Dietary Proteins, lcsh:Nutrition. Foods and food supply, Fat content, lcsh:TX341-641, 610 Medicine & health, 030209 endocrinology & metabolism, Diet, High-Fat, Article, 03 medical and health sciences, Animal science, Diet, Protein-Restricted, Intramyocellular lipids, Muscle, Skeletal, Lipid Metabolism, Crossover study, Dietary Fats, Food Science
وصف الملف: application/pdf
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المؤلفون: Erling Falk, Christian Bo Poulsen, Søren K. Moestrup, Brynjulf Mortensen, Ludovic Drouet, Rozh H Al-Mashhadi, Jacob F. Bentzon, Anna-Karin L. Robertson, Lars Poulsen Tolbod, Karin von Wachenfeldt, Jens Rolighed Larsen, Lars Bo Nielsen, Jesper Thygesen, Ahmed Ludvigsen Al-Mashhadi, Björn Frendéus
المصدر: Journal of Diabetes Research, Vol 2018 (2018)
Journal of Diabetes Research
Al-Mashhadi, A L, Poulsen, C B, von Wachenfeldt, K, Robertson, A-K, Bentzon, J F, Nielsen, L B, Thygesen, J, Tolbod, L P, Larsen, J R, Moestrup, S K, Frendéus, B, Mortensen, B, Drouet, L, Al-Mashhadi, R H & Falk, E 2018, ' Diet-Induced Abdominal Obesity, Metabolic Changes, and Atherosclerosis in Hypercholesterolemic Minipigs ', Journal of Diabetes Research, vol. 2018, 6823193 . https://doi.org/10.1155/2018/6823193
Al-Mashhadi, A L, Poulsen, C B, von Wachenfeldt, K, Robertson, A-K L, Bentzon, J F, Nielsen, L B, Thygesen, J, Tolbod, L P, Larsen, J R, Moestrup, S K, Frendéus, B, Mortensen, B, Drouet, J-L, Al-Mashhadi, R & Falk, E 2018, ' Diet-Induced Abdominal Obesity, Metabolic Changes, and Atherosclerosis in Hypercholesterolemic Minipigs ', Journal of Diabetes Research, vol. 2018, 6823193 . https://doi.org/10.1155/2018/6823193
BASE-Bielefeld Academic Search Engineمصطلحات موضوعية: 0301 basic medicine, Swine, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Familial hypercholesterolemia, 030204 cardiovascular system & hematology, Cholesterol, HDL/metabolism, lcsh:Diseases of the endocrine glands. Clinical endocrinology, chemistry.chemical_compound, 0302 clinical medicine, Endocrinology, Triglycerides/metabolism, Obesity, Abdominal/etiology, Abdominal obesity, Metabolic Syndrome, Atherosclerosis/etiology, Hypercholesterolemia/etiology, Obesity, Abdominal, Body Composition, Cholesterol, LDL/metabolism, Swine, Miniature, Female, medicine.symptom, Research Article, medicine.medical_specialty, Intra-Abdominal Fat, Article Subject, Body Composition/physiology, Hypercholesterolemia, Subcutaneous Fat, Metabolic Syndrome/etiology, Diet, High-Fat, 03 medical and health sciences, Insulin resistance, Internal medicine, medicine, Diet, High-Fat/adverse effects, Animals, Triglycerides, lcsh:RC648-665, Cholesterol, business.industry, Insulin, Cholesterol, HDL, Cholesterol, LDL, medicine.disease, Atherosclerosis, Obesity, 030104 developmental biology, chemistry, Intra-Abdominal Fat/metabolism, Metabolic syndrome, Insulin Resistance, business, Insulin Resistance/physiology, Subcutaneous Fat/metabolism
وصف الملف: application/pdf; text/xhtml
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المؤلفون: Honey Modi, Bernard Thorens, Fu-Ping Zhang, Salima Metref, Ole D. Madsen, Matti Poutanen, Romano Regazzi, Cécile Jacovetti, David Tarussio, Tracy Gorman, Serge Nef, Pia Rantakari
المصدر: Diabetes
Diabetes, Vol. 64, No 12 (2015) pp. 4148-4157مصطلحات موضوعية: Male, Aging, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Apoptosis, Receptor, IGF Type 1, Tissue Culture Techniques, 0302 clinical medicine, Pregnancy, Insulin-Secreting Cells, Insulin Secretion, Insulin, ddc:576.5, Receptor, Mice, Knockout, 0303 health sciences, Sex Characteristics, Gene Expression Regulation, Developmental, Insulin-Secreting Cells/cytology/pathology/secretion, 3. Good health, Allostasis, Receptor, IGF Type 1/agonists/genetics/metabolism, Female, Signal transduction, Glucose Intolerance/etiology/metabolism/pathology, Signal Transduction, medicine.medical_specialty, Transgene, 030209 endocrinology & metabolism, Mice, Transgenic, Biology, Diet, High-Fat, Insulin-Like Growth Factor II/genetics/metabolism, 03 medical and health sciences, Insulin resistance, Insulin-Like Growth Factor II, Internal medicine, Glucose Intolerance, Internal Medicine, medicine, Diet, High-Fat/adverse effects, Animals, Autocrine signalling, Crosses, Genetic, 030304 developmental biology, Cell Proliferation, Insulin/secretion, Cell growth, Growth factor, medicine.disease, Endocrinology, Insulin Resistance
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20cafeb884136f14b1de1dfb2717aa77
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المؤلفون: Paul Johnson, Céline Cruciani-Guglielmacci, Julie Hardy, Christophe Magnan, Naila S. Mannan, Julia Parnis, James Shapiro, Xi Chen, Héctor H. Valdivia, Isabelle Leclerc, Piero Marchetti, LeAnne Carmichael, Bernard Thorens, Guy A. Rutter, A. Marmugi, Lorenzo Piemonti, Domenico Bosco, Mark Ibberson
المساهمون: Faculty of Economic and Social Sciences and Solvay Business School, Pathology/molecular and cellular medicine, Marmugi, Alice, Parnis, Julia, Chen, Xi, Carmichael, Leanne, Hardy, Julie, Mannan, Naila, Marchetti, Piero, Piemonti, Lorenzo, Bosco, Domenico, Johnson, Paul, Shapiro, James A. M., Cruciani Guglielmacci, Cã©line, Magnan, Christophe, Ibberson, Mark, Thorens, Bernard, Valdivia, Héctor H., Rutter, Guy A., Leclerc, Isabelle, Diabetes UK, Medical Research Council (MRC), Biotechnology and Biological Sciences Research Council (BBSRC)
المصدر: Diabetes, Vol. 65, No 4 (2016) pp. 1009-21
Diabetesمصطلحات موضوعية: 0301 basic medicine, Calcium-Binding Proteins/genetics/physiology, Endocrinology, Diabetes and Metabolism, Mice, Obese, Endoplasmic Reticulum/drug effects/metabolism, Endoplasmic Reticulum, Obese, Mice, 0302 clinical medicine, Obesity/metabolism/pathology, ENDOPLASMIC-RETICULUM STRESS, Calcium-binding protein, Insulin-Secreting Cells, IN-VIVO, 11 Medical and Health Sciences, Dietary Fat, Cells, Cultured, Calcium-Binding Protein, Mice, Knockout, Cultured, ddc:617, Ryanodine receptor, Research Support, Non-U.S. Gov't, Insulin-Secreting Cells/drug effects/metabolism/pathology, ACTIVATED PROTEIN-KINASE, Endoplasmic Reticulum Stress, 3. Good health, RYANODINE RECEPTORS, Lipotoxicity, ISLETS, Calcium Signaling/drug effects, HEART, CALCIUM-RELEASE, Life Sciences & Biomedicine, Glucose 6-phosphatase, medicine.medical_specialty, Calcium/metabolism, Cells, Knockout, High-Fat/adverse effects, 030209 endocrinology & metabolism, Biology, Diet, High-Fat, Endocrinology & Metabolism, RESISTANT CELLS, 03 medical and health sciences, Insulin resistance, Dietary Fats/toxicity, STIMULATED INSULIN-SECRETION, Downregulation and upregulation, Research Support, N.I.H., Extramural, Internal medicine, medicine, Internal Medicine, Journal Article, Endoplasmic Reticulum Stress/drug effects, Animals, Calcium Signaling, Obesity, Endoplasmic Reticulum Stre, Science & Technology, Animal, Endoplasmic reticulum, Calcium-Binding Proteins, medicine.disease, Dietary Fats, Diet, GLUCOSE-6-PHOSPHATASE, 030104 developmental biology, Endocrinology, Islet Studies, Insulin-Secreting Cell, Unfolded protein response, biology.protein, Calcium
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e9e1e8170fd34c282b8360fb55eba60
http://hdl.handle.net/11568/778795 -
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المؤلفون: Jean-Christophe Copin, Yvan Gasche, Karl Lothard Schaller, Rafaela F. da Silva, Andrew M. Fukuda, Jérôme Badaut
المصدر: Journal of Neuroinflammation
Journal of Neuroinflammation, Vol 9, Iss 1, p 132 (2012)
Journal of Neuroinflammation, Vol. 9 (2012) P. 132مصطلحات موضوعية: Apolipoprotein E, Pathology, Aging, Cerebral arteries, lcsh:RC346-429, chemistry.chemical_compound, Mice, 0302 clinical medicine, Arginase/genetics/metabolism, Blood-Brain Barrier/enzymology/physiopathology, Apolipoproteins E/deficiency/genetics, Mice, Knockout, 0303 health sciences, Enzyme Activation/genetics, ddc:617, General Neuroscience, Astrogliosis, Up-Regulation, Arginase, medicine.anatomical_structure, Aquaporin 4, Neurology, Blood-Brain Barrier, Blood brain barrier, Neurovascular unit, medicine.symptom, medicine.medical_specialty, Immunology, Inflammation, Biology, Blood–brain barrier, Diet, High-Fat, Atherosclerosis/enzymology/genetics/physiopathology, Nitric oxide, Up-Regulation/genetics, 03 medical and health sciences, Cellular and Molecular Neuroscience, Apolipoproteins E, Internal medicine, Diet, High-Fat/adverse effects, medicine, Animals, Aging/genetics/metabolism/pathology, lcsh:Neurology. Diseases of the nervous system, 030304 developmental biology, Research, Water channel, medicine.disease, Atherosclerosis, ddc:616.8, Enzyme Activation, Mice, Inbred C57BL, Endocrinology, chemistry, Brain aging, Nitric Oxide/metabolism, 030217 neurology & neurosurgery
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