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المؤلفون: Jan Böhm, Anna Junttila, Sirpa Jalkanen, Jukka-Pekka Mecklin, Olli Helminen, Istvan Kenessey, Juha P. Väyrynen, Maarit Ahtiainen, Ilmo Kellokumpu, Johanna Mrena, Teijo Kuopio
المصدر: British Journal of Cancer
مصطلحات موضوعية: Oncology, Adult, Male, Cancer Research, medicine.medical_specialty, Programmed Cell Death 1 Receptor, Adenocarcinoma, Article, B7-H1 Antigen, Immune tolerance, Immunophenotyping, 03 medical and health sciences, 0302 clinical medicine, Immune system, Stomach Neoplasms, Internal medicine, PD-L1, medicine, Immune Tolerance, Humans, Aged, biology, Molecular medicine, business.industry, Proportional hazards model, Macrophages, Confounding, Immunosurveillance, mahasyöpä, Cancer, ennusteet, Middle Aged, medicine.disease, immuunivaste, 030220 oncology & carcinogenesis, biology.protein, syöpätaudit, fenotyyppi, Female, Tumor Escape, business, CD8, Signal Transduction
وصف الملف: application/pdf; fulltext
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المؤلفون: Juha Kononen, Nina Rintanen, Rami Mäkelä, Ville Härmä, Juha Rantala, Antti Arjonen, Teijo Kuopio
المصدر: Lung Cancer. 145:27-32
مصطلحات موضوعية: 0301 basic medicine, Pulmonary and Respiratory Medicine, Oncology, Cancer Research, medicine.medical_specialty, Lung Neoplasms, Thymoma, medicine.medical_treatment, Malignancy, Targeted therapy, Efficacy, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Humans, Medicine, Chemotherapy, Cetuximab, business.industry, Thymus Neoplasms, medicine.disease, 030104 developmental biology, Pharmaceutical Preparations, 030220 oncology & carcinogenesis, Personalized medicine, Neoplasm Recurrence, Local, business, Ex vivo, medicine.drug
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المؤلفون: Rami Mäkelä, Nina Rintanen, Kaisa Lehtomäki, Juha Rantala, Laura Lahtinen, Pirkko-Liisa Kellokumpu-Lehtinen, Teijo Kuopio, Juha Kononen, Ivana Kholová
المصدر: Anticancer Research. 39:5867-5877
مصطلحات موضوعية: MAPK/ERK pathway, Cancer Research, Lung Neoplasms, Colorectal cancer, MAP Kinase Kinase 1, Somatic evolution in cancer, Clonal Evolution, 03 medical and health sciences, 0302 clinical medicine, Antineoplastic Combined Chemotherapy Protocols, Biomarkers, Tumor, medicine, Adjuvant therapy, Humans, Liquid biopsy, Capecitabine, Aged, business.industry, High-Throughput Nucleotide Sequencing, General Medicine, Prognosis, medicine.disease, Primary tumor, Oxaliplatin, Oncology, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, Mutation, Cancer research, Biomarker (medicine), Female, Mitogen-Activated Protein Kinases, Colorectal Neoplasms, business, Ex vivo
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40734bd863e63a3826fb78387ff59514
https://doi.org/10.21873/anticanres.13791 -
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المؤلفون: Caj Haglund, Elisa Lappi-Blanco, Tiina Vesterinen, Teijo Kuopio, Harri Mustonen, Kaisa Salmenkivi, Olli Carpén, Paula Vainio, Timo Paavonen, Aija Knuuttila, Johanna Arola
المساهمون: HUSLAB, Institute for Molecular Medicine Finland, Department of Pathology, University of Helsinki, Helsinki Institute of Life Science HiLIFE, HUS Abdominal Center, Clinicum, Department of Surgery, Department of Medicine, Keuhkosairauksien yksikkö, HUS Heart and Lung Center, Precision Cancer Pathology, Olli Mikael Carpen / Principal Investigator, Medicum, Research Program in Systems Oncology, Research Programs Unit, II kirurgian klinikka, CAN-PRO - Translational Cancer Medicine Program, Faculty of Medicine
المصدر: Virchows Archiv
مصطلحات موضوعية: Male, 0301 basic medicine, Lung Neoplasms, Proliferation index, biopankit, Disease, Neuroendocrine tumors, keuhkosyöpä, Pulmonary carcinoid, Tumour tissue, 0302 clinical medicine, RARE, Registries, INDEX, Finland, Biological Specimen Banks, OUTCOMES, rare cancer, SURGICAL RESECTION, General Medicine, Middle Aged, Prognosis, Biobank, 3. Good health, biobank, 030220 oncology & carcinogenesis, Mediastinal lymph node, SURVIVAL, Original Article, Female, BURDEN, pulmonary carcinoid, Adult, medicine.medical_specialty, 3122 Cancers, Carcinoid Tumor, Pathology and Forensic Medicine, 03 medical and health sciences, Internal medicine, medicine, QUALITY, Humans, harvinaiset taudit, Molecular Biology, business.industry, Rare cancer, ennusteet, Cell Biology, medicine.disease, Carcinoma, Neuroendocrine, Cancer registry, Pulmonary carcinoid tumour, 030104 developmental biology, EXPERIENCE, prognosis, 3111 Biomedicine, business, NEUROENDOCRINE TUMORS
وصف الملف: application/pdf; fulltext
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المؤلفون: Teijo Kuopio, Noora Porkka, Maarit Ahtiainen, Toni T. Seppälä, Jukka-Pekka Mecklin, Jan Böhm, Päivi Peltomäki, Samuli Eldfors, Laura Lahtinen
المساهمون: Department of Medical and Clinical Genetics, University of Helsinki, Medicum, Institute for Molecular Medicine Finland, Clinicum, Department of Surgery, HUS Abdominal Center
المصدر: International Journal of Cancer. 145:87-98
مصطلحات موضوعية: Cancer Research, MICROSATELLITE INSTABILITY, DNA mismatch repair, MISMATCH-REPAIR DEFICIENCY, Gene mutation, medicine.disease_cause, 0302 clinical medicine, lynch syndrome, Finland, Molecular Epidemiology, education.field_of_study, Mutation, ISLAND METHYLATOR PHENOTYPE, NONPOLYPOSIS COLORECTAL-CANCER, lynch-like syndrome, TUMORS, Lynch syndrome, 3. Good health, Oncology, 030220 oncology & carcinogenesis, syöpätaudit, Colorectal Neoplasms, MutL Protein Homolog 1, Lynch-like syndrome, Adult, 3122 Cancers, Population, suolistosyövät, CpG island methylator phenotype, Biology, ta3111, FREQUENCY, MLH1, 03 medical and health sciences, Germline mutation, colorectal carcinoma, BRAF MUTATION, COLON, medicine, Humans, Lynchin oireyhtymä, education, neoplasms, MSI, Aged, Retrospective Studies, CpG Island Methylator Phenotype, Microsatellite instability, DNA, SOMATIC MUTATIONS, ta3122, CpG Island Methylator phenotype, medicine.disease, Colorectal Neoplasms, Hereditary Nonpolyposis, digestive system diseases, COPY NUMBER, Cancer research
وصف الملف: application/pdf; fulltext
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المؤلفون: Anna Junttila, Juha P. Väyrynen, Teijo Kuopio, Maarit Ahtiainen, Johanna Mrena, Eero Sihvo, Olli Helminen
المصدر: Acta oncologica (Stockholm, Sweden). 60(4)
مصطلحات موضوعية: Oncology, medicine.medical_specialty, Esophageal Neoplasms, Cell, MEDLINE, B7-H1 Antigen, 030218 nuclear medicine & medical imaging, 03 medical and health sciences, 0302 clinical medicine, Immune system, Lymphocytes, Tumor-Infiltrating, Internal medicine, medicine, Biomarkers, Tumor, Humans, Radiology, Nuclear Medicine and imaging, Cancer death, business.industry, Cancer, Hematology, General Medicine, Esophageal cancer, medicine.disease, Prognosis, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Pd l1 expression, business
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المؤلفون: Maarit Ahtiainen, Satu Tommola, Tuula Salo, Heini Huhtala, Markus Rautiainen, Sanna Toppila-Salmi, Timo Paavonen, Ahmed Al-Samadi, Miia Seppälä, Sanni Tervo, Teijo Kuopio
المساهمون: Medicum, University of Helsinki, HUSLAB, Department of Oral and Maxillofacial Diseases, HUS Head and Neck Center, HUS Inflammation Center, Department of Pathology, Department of Dermatology, Allergology and Venereology, Helsinki University Hospital Area
مصطلحات موضوعية: 0301 basic medicine, Programmed Cell Death 1 Receptor, biomarkkerit, tongue squamous cell carcinoma, LYMPHOCYTES, 0302 clinical medicine, Immunology and Allergy, EPIDEMIOLOGY, Receptor, DISSECTION, Aged, 80 and over, 11832 Microbiology and virology, LIGAND 1 PD-L1, Mucous membrane, molekyylit, General Medicine, Middle Aged, CANCER, 3. Good health, Tongue Neoplasms, medicine.anatomical_structure, 030220 oncology & carcinogenesis, immunohistochemistry, Carcinoma, Squamous Cell, SURVIVAL, Immunohistochemistry, syöpätaudit, Programmed cell death protein 1 (PD-1), Microbiology (medical), Adult, Adolescent, Pathology and Forensic Medicine, 03 medical and health sciences, Young Adult, Immune system, Antigen, Tongue, POOR-PROGNOSIS, medicine, Biomarkers, Tumor, Humans, NECK, Aged, molecular marker, business.industry, HUMAN-PAPILLOMAVIRUS, Cancer, ennusteet, programmed cell death protein 1 (PD‐1), medicine.disease, Immune checkpoint, 030104 developmental biology, Cancer research, T-CELLS, prognosis, 3111 Biomedicine, business
وصف الملف: application/pdf; fulltext
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85a39b6813b497cc9565aa57f24589a4
http://hdl.handle.net/10138/335432 -
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المؤلفون: Thomas Helleday, Janne Lehtiö, Teijo Kuopio, Ville Härmä, Rami Mäkelä, Aldwin Suryo Rahmanto, Juha Kononen, Antti Arjonen, Juha Rantala, Olle Sangfelt
المصدر: Neoplasia: An International Journal for Oncology Research, Vol 22, Iss 9, Pp 390-398 (2020)
Neoplasia (New York, N.Y.)مصطلحات موضوعية: Adult, 0301 basic medicine, Original article, Cancer Research, Cell type, Lung Neoplasms, medicine.medical_treatment, DNA Mutational Analysis, Antineoplastic Agents, Epithelial-myoepithelial carcinoma, lcsh:RC254-282, Myoepithelioma, Targeted therapy, Cancer diagnostics, 03 medical and health sciences, 0302 clinical medicine, Biomarkers, Tumor, Tumor Cells, Cultured, Carcinoma, medicine, Humans, Everolimus, Molecular Targeted Therapy, Epithelial–myoepithelial carcinoma, Ex vivo drug screening, Chemotherapy, HCA, High content assay, business.industry, Gene Expression Profiling, Myoepithelial cell, Cancer, Prognosis, Salivary Gland Neoplasms, medicine.disease, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Personalized medicine, High-Throughput Screening Assays, 030104 developmental biology, 030220 oncology & carcinogenesis, Mutation, Cancer research, EMC, Epithelial–myoepithelial carcinoma, Female, RPPA, Reverse phase protein arrays, business, Ex vivo
وصف الملف: application/pdf
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المؤلفون: Teijo Kuopio, Samuli Eldfors, Noora Porkka, Alisa Olkinuora, Maarit Ahtiainen, Jukka-Pekka Mecklin, Päivi Peltomäki, Henrikki Almusa
المساهمون: Department of Medical and Clinical Genetics, Institute for Molecular Medicine Finland, University of Helsinki
المصدر: Oncotarget
مصطلحات موضوعية: 0301 basic medicine, Oncology, medicine.medical_specialty, DNA mismatch repair, 3122 Cancers, medicine.disease_cause, 03 medical and health sciences, 0302 clinical medicine, Breast cancer, Germline mutation, Internal medicine, medicine, somatic mutation, breast carcinoma, Lynchin oireyhtymä, MSI, perinnölliset taudit, rintasyöpä, business.industry, Cancer, medicine.disease, Lynch syndrome, digestive system diseases, 3. Good health, 030104 developmental biology, syöpägeenit, 030220 oncology & carcinogenesis, Medical genetics, syöpätaudit, 3111 Biomedicine, mutaatiot, Carcinogenesis, Breast carcinoma, business, Research Paper
وصف الملف: application/pdf; fulltext
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08f2d7210d87afadc0eb13ac6e179219
http://urn.fi/URN:NBN:fi:jyu-202004242885 -
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المؤلفون: Christopher Whelan, Urho Kujala, Arto Lehisto, Katri Pylkäs, Jaakko Kaprio, Eija Laakkonen, Anna Podgornaia, Juha Paloneva, Markus Juonala, Jukka Koskela, Heikki Joensuu, Tuomo Meretoja, Jari Laukkanen, Mika Kähönen, Matti Pirinen, Priit Palta, Nina Mars, Marja-Riitta Taskinen, Joseph Maranville, Teemu Niiranen, Mari Kaunisto, Joni Turunen, Shabbeer Hassan, Christian Klose, Kaisa Tasanen, Katariina Hannula-Jouppi, Tiinamaija Tuomi, Mathias Gerl, Johanna Schleutker, Tomi Makela, Kari Pulkki, Teea Salmi, Joel Rämö, Aarno Palotie, Juha Sinisalo, Valtteri Julkunen, Lauri Aaltonen, Rubina Tabassum, Antti Palomäki, Teijo Kuopio, Timo Sipilä, Niina Matikainen, Michal Surma, Anu-Maria Loukola, Martti Färkkilä, Pietari Ripatti, Paola Bronson, Andrea Ganna, Javier Gracia-Tabuenca, Kimmo Savinainen, Hannele Laivuori
المساهمون: Samuli Olli Ripatti / Principal Investigator, Complex Disease Genetics, Institute for Molecular Medicine Finland, Genomics of Neurological and Neuropsychiatric Disorders, Doctoral Programme in Population Health, Clinicum, Doctoral Programme in Clinical Research, HUS Internal Medicine and Rehabilitation, HUS Abdominal Center, University Management, Pregnancy and Genes, HUS Gynecology and Obstetrics, Medicum, Department of Mathematics and Statistics, Helsinki Institute for Information Technology, Centre of Excellence in Complex Disease Genetics, Statistical and population genetics, Biostatistics Helsinki, Doctoral Programme in Mathematics and Statistics, Research Programs Unit, Research Programme of Molecular Medicine, Aarno Palotie / Principal Investigator, Doctoral Programme Brain & Mind, Marja-Riitta Taskinen Research Group, Faculty Common Matters (Faculty of Social Sciences), Department of Public Health, Doctoral Programme in Social Sciences, Genetic Epidemiology, Jaakko Kaprio / Principal Investigator, Biosciences, Doctoral Programme in Biomedicine, Data Science Genetic Epidemiology Lab, Department of Food and Nutrition, Departments of Faculty of Veterinary Medicine, Quantitative Genetics, Faculty of Medicine, HUSLAB, Helsinki Institute of Life Science HiLIFE, Department of Biochemistry and Developmental Biology, Mäkelä Lab, Doctoral Programme in Integrative Life Science, Department of Pathology, Department of Oncology, Heikki Joensuu / Principal Investigator, HUS Comprehensive Cancer Center, Department of Medicine, HUS Heart and Lung Center, HUS Inflammation Center, Department of Medical and Clinical Genetics, Genome-Scale Biology (GSB) Research Program, Lauri Antti Aaltonen / Principal Investigator, Olli Mikael Carpen / Principal Investigator, Precision Cancer Pathology, Department of Neurosciences, HUS Neurocenter, Tiinamaija Tuomi Research Group, Department of Ophthalmology and Otorhinolaryngology, HUS Head and Neck Center, Korva-, nenä- ja kurkkutautien klinikka, Doctoral Programme in Clinical Veterinary Medicine, Department of Dermatology, Allergology and Venereology, HYKS erva, Päijät-Häme Welfare Consortium, University of Helsinki
المصدر: Nature communications, vol 10, iss 1
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Nature Communicationsمصطلحات موضوعية: 0301 basic medicine, False discovery rate, Science, General Physics and Astronomy, Disease, 030204 cardiovascular system & hematology, Biology, Cardiovascular, Genome-wide association studies, Article, General Biochemistry, Genetics and Molecular Biology, Plasma, 03 medical and health sciences, 0302 clinical medicine, Genetics, Humans, FinnGen Project, lcsh:Science, Lipoprotein lipase, Multidisciplinary, Prevention, Human Genome, 1184 Genetics, developmental biology, physiology, Lipid metabolism, Cardiovascular genetics, General Chemistry, Heritability, Lipidome, Lipids, Phenotype, Genetic architecture, 3. Good health, Cardiovascular diseases, Heart Disease, 030104 developmental biology, Cardiovascular Diseases, Lipidomics, lcsh:Q, lipids (amino acids, peptides, and proteins), 3111 Biomedicine, Genome-Wide Association Study
وصف الملف: application/pdf