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المؤلفون: István Csabai, Judit Moldvay, János Fillinger, Zoltan Szallasi, Viktoria Tisza, Anders Gorm Pedersen, Marcin Krzystanek, Dávid Szüts, Miklos Diossy, Orsolya Rusz, Zsofia Sztupinszki, Judit Borcsok, József Tímár, Sándor Spisák
المصدر: npj Precision Oncology, Vol 5, Iss 1, Pp 1-8 (2021)
NPJ Precision Oncology
Diossy, M, Sztupinszki, Z, Borcsok, J, Krzystanek, M, Tisza, V, Spisak, S, Rusz, O, Timar, J, Csabai, I, Fillinger, J, Moldvay, J, Pedersen, A G, Szuts, D & Szallasi, Z 2021, ' A subset of lung cancer cases shows robust signs of homologous recombination deficiency associated genomic mutational signatures ', n p j Precision Oncology, vol. 5, no. 1, 55 . https://doi.org/10.1038/s41698-021-00199-8مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Biology, Article, Prostate cancer, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, SDG 3 - Good Health and Well-being, medicine, Lung cancer, Gene, Exome sequencing, Loss function, RC254-282, Lung, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, medicine.disease, Squamous carcinoma, 030104 developmental biology, medicine.anatomical_structure, Oncology, chemistry, 030220 oncology & carcinogenesis, PARP inhibitor, Cancer research, Adenocarcinoma, Homologous recombination, Non-small-cell lung cancer, DNA
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URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b8487d7c44c3decc857387b2118d044
https://doaj.org/article/406462c44b26424ba7040c4796c0ef2d -
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المؤلفون: Matthew L. Freedman, Mark Pomerantz, Orsolya Rusz, Zsofia Sztupinszki, Sándor Spisák, Viktoria Tisza, Marcin Krzystanek, Miklos Diossy, Judit Borcsok, Zoltan Szallasi, István Csabai
المصدر: Clin Cancer Res
مصطلحات موضوعية: Male, 0301 basic medicine, Cancer Research, Poly(ADP-ribose) Polymerase Inhibitors, Biology, medicine.disease_cause, Article, Germline, 03 medical and health sciences, Prostate cancer, 0302 clinical medicine, Prostate, Exome Sequencing, Biomarkers, Tumor, medicine, Humans, Homologous Recombination, Gene, Exome sequencing, BRCA2 Protein, Mutation, BRCA1 Protein, Prostatic Neoplasms, Prognosis, medicine.disease, Gene Expression Regulation, Neoplastic, 030104 developmental biology, medicine.anatomical_structure, Oncology, 030220 oncology & carcinogenesis, PARP inhibitor, Cancer research, Homologous recombination
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ab2fd003cb36f7c422a938b5eac7bb6
https://doi.org/10.1158/1078-0432.ccr-19-2135 -
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المؤلفون: Marcin Krzystanek, Aron Charles Eklund, István Csabai, Miklos Diossy, Anders Gorm Pedersen, Zoltan Szallasi, Zsofia Sztupinszki, Judit Borcsok
المصدر: Briefings in bioinformatics. 22(6)
مصطلحات موضوعية: Computer science, Posterior probability, Cytological Techniques, 03 medical and health sciences, 0302 clinical medicine, Cancer genome, Neoplasms, Databases, Genetic, Humans, Molecular Biology, Exome sequencing, 030304 developmental biology, 0303 health sciences, Artifact (error), Models, Statistical, Orientation (computer vision), business.industry, Detector, High-Throughput Nucleotide Sequencing, Reproducibility of Results, Pattern recognition, DNA, Neoplasm, Sequence Analysis, DNA, Templates, Genetic, Tissue specimen, 030220 oncology & carcinogenesis, Mutation (genetic algorithm), Mutation, Artificial intelligence, business, Artifacts, Algorithms, Information Systems
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86ad93f6e799a883a7a64d322247fe09
https://pubmed.ncbi.nlm.nih.gov/34015811 -
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المؤلفون: Dmitry Pruss, Zoltan Szallasi, Gábor Cserni, Janina Kulka, Kirsten Timms, Chris Neff, István Csabai, Orsolya Rusz, József Tímár, Cara Solimeno, Borbála Székely, Tamás Zombori, Miklos Diossy, Zsofia Sztupinszki, Marcin Krzystanek, Erika Tóth, Aron Charles Eklund, Orsolya Kiss, Lilla Reiniger
المصدر: Diossy, M, Reiniger, L, Sztupinszki, Z M, Krzystanek, M, Timms, K M, Neff, C, Solimeno, C, Pruss, D, Eklund, A C, Tóth, E, Kiss, O, Rusz, O, Cserni, G, Zombori, T, Székely, B, Tímár, J, Csabai, I & Szallasi, Z 2018, ' Breast cancer brain metastases show increased levels of genomic aberration based homologous recombination deficiency scores relative to their corresponding primary tumors ', Annals of Oncology, vol. 29, no. 9, pp. 1948-1954 . https://doi.org/10.1093/annonc/mdy216
مصطلحات موضوعية: 0301 basic medicine, Oncology, medicine.medical_specialty, Cancer therapy, 03 medical and health sciences, Breast cancer, 0302 clinical medicine, SDG 3 - Good Health and Well-being, Internal medicine, DNA Mutational Analysis, medicine, Exome sequencing, business.industry, Brain metastasis, Hematology, medicine.disease, Primary tumor, Clinical trial, 030104 developmental biology, 030220 oncology & carcinogenesis, PARP inhibitor, Cohort, business
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URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9105edc33119ce50680dfa00aef0561c
https://doi.org/10.1093/annonc/mdy216 -
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المؤلفون: Aron Charles Eklund, Ali Syed, Lilla Reiniger, Zoltan Szallasi, Miklos Diossy, Francesco Favero, Nicolai Juul Birkbak, Zsofia Sztupinszki, Marcin Krzystanek, István Csabai
المصدر: npj Breast Cancer, Vol 4, Iss 1, Pp 1-4 (2018)
Sztupinszki, Z, Diossy, M, Krzystanek, M, Reiniger, L, Csabai, I, Favero, F, Birkbak, N J, Eklund, A C, Syed, A & Szallasi, Z 2018, ' Migrating the SNP array-based homologous recombination deficiency measures to next generation sequencing data of breast cancer ', n p j Breast Cancer, vol. 4, 16 . https://doi.org/10.1038/s41523-018-0066-6
Sztupinszki, Z, Diossy, M, Krzystanek, M, Reiniger, L, Csabai, I, Favero, F, Birkbak, N J, Eklund, A C, Syed, A & Szallasi, Z 2018, ' Migrating the SNP array-based homologous recombination deficiency measures to next generation sequencing data of breast cancer ', npj Breast Cancer, vol. 4, no. 1, 16, pp. 1-4 . https://doi.org/10.1038/s41523-018-0066-6
NPJ Breast Cancerمصطلحات موضوعية: 0301 basic medicine, Computational biology, Biology, Brief Communication, Genome, lcsh:RC254-282, DNA sequencing, 03 medical and health sciences, symbols.namesake, 0302 clinical medicine, Breast cancer, SDG 3 - Good Health and Well-being, medicine, SNP, Pharmacology (medical), Radiology, Nuclear Medicine and imaging, Exome, medicine.disease, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Pearson product-moment correlation coefficient, Data set, 030104 developmental biology, Oncology, 030220 oncology & carcinogenesis, symbols, SNP array
وصف الملف: application/pdf
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المؤلفون: Thomas B.K. Watkins, Emilia L. Lim, Selvaraju Veeriah, István Csabai, Maria Greco, Nicholas McGranahan, Gareth A. Wilson, Stefan Boeing, Zoltan Szallasi, Jiri Bartek, Dhruva Biswas, Dijana Djureinovic, Maise Al Bakir, Allan Hackshaw, Charles Swanton, Christopher Abbosh, Rachel Rosenthal, Crispin T. Hiley, Javier Herrero, Krisztián Papp, Kevin Litchfield, Patrick Micke, Judit Moldvay, Balazs Dome, Arul M. Chinnaiyan, Yin Wu, Linnea La Fleur, Marcin Skrzypski, János Fillinger, Mariam Jamal-Hanjani, Marcin Krzystanek, Johan Botling, Nicolai Juul Birkbak, David Allan Moore, Hans Brunnström
المصدر: Biswas, D, Birkbak, N J, Rosenthal, R, Hiley, C T, Lim, E L, Papp, K, Boeing, S, Krzystanek, M, Djureinovic, D, La Fleur, L, Greco, M, Döme, B, Fillinger, J, Brunnström, H, Wu, Y, Moore, D A, Skrzypski, M, Abbosh, C, Litchfield, K, Al Bakir, M, Watkins, T B K, Veeriah, S, Wilson, G A, Jamal-Hanjani, M, Moldvay, J, Botling, J, Chinnaiyan, A M, Micke, P, Hackshaw, A, Bartek, J, Csabai, I, Szallasi, Z, Herrero, J, McGranahan, N, Swanton, C & TRACERx Consortium 2019, ' A clonal expression biomarker associates with lung cancer mortality ', Nature Medicine, vol. 25, no. 10, pp. 1540-1548 . https://doi.org/10.1038/s41591-019-0595-z
مصطلحات موضوعية: 0301 basic medicine, Oncology, Male, medicine.medical_specialty, Lung Neoplasms, Tumour heterogeneity, DNA Copy Number Variations, Disease, Biology, General Biochemistry, Genetics and Molecular Biology, Disease-Free Survival, Article, Transcriptome, Clonal Evolution, 03 medical and health sciences, Genetic Heterogeneity, 0302 clinical medicine, Risk Factors, Internal medicine, Exome Sequencing, medicine, Biomarkers, Tumor, Humans, Exome, Lung cancer, Exome sequencing, Aged, Genetic heterogeneity, Cancer, General Medicine, medicine.disease, Prognosis, Gene Expression Regulation, Neoplastic, 030104 developmental biology, 030220 oncology & carcinogenesis, Biomarker (medicine), Female
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2225be7c4547fd49cd0909f53c27198
https://pure.au.dk/portal/da/publications/a-clonal-expression-biomarker-associates-with-lung-cancer-mortality(a2adabfd-14ed-486e-b04b-03d3515e134f).html -
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المؤلفون: Lilla Reiniger, Dezső Ribli, Dávid Szüts, Zsofia Sztupinszki, Tibor Glasz, Marcin Krzystanek, István Csabai, Eszter Németh, Orsolya Pipek, Zoltan Szallasi, Judit Moldvay
المصدر: International journal of cancer. 145(3)
مصطلحات موضوعية: Cancer Research, Lung Neoplasms, Afatinib, Adenocarcinoma of Lung, medicine.disease_cause, 03 medical and health sciences, T790M, Genomic Imprinting, 0302 clinical medicine, medicine, Humans, Neoplasm Metastasis, Gene, Allele frequency, Protein Kinase Inhibitors, Retrospective Studies, Cisplatin, Gene Rearrangement, Mutation, Models, Genetic, business.industry, Cancer, Gefitinib, medicine.disease, ErbB Receptors, Oncology, Mutagenesis, 030220 oncology & carcinogenesis, Cancer research, Adenocarcinoma, business, Algorithms, medicine.drug, Genome-Wide Association Study
وصف الملف: application/pdf
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المؤلفون: Charles Swanton, Zoltan Szallasi, Gábor E. Tusnády, Dávid Szüts, Marcin Krzystanek, János Molnár, Orsolya Pipek, István Csabai, Ádám Póti, Nnennaya Kanu
المصدر: G3: Genes|Genomes|Genetics
Molnar, J, Poti, A, Pipek, O, Krzystanek, M, Kanu, N, Swanton, C, Tusnady, G E, Szallasi, Z I, Csabai, I & Szuets, D 2014, ' The Genome of the Chicken DT40 Bursal Lymphoma Cell Line ', G3: Genes, Genomes, Genetics (Bethesda), vol. 4, no. 11, pp. 2231-2240 . https://doi.org/10.1534/g3.114.013482مصطلحات موضوعية: Cancer genome sequencing, Genome evolution, Lymphoma, Karyotype, Biology, Investigations, Genome, Polymorphism, Single Nucleotide, gene targeting, Proto-Oncogene Proteins c-myc, 03 medical and health sciences, Phosphatidylinositol 3-Kinases, 0302 clinical medicine, single nucleotide polymorphism, Gene density, Cell Line, Tumor, Genetics, Animals, tumor suppressor gene, Molecular Biology, Gene, Genetics (clinical), 030304 developmental biology, 0303 health sciences, Shotgun sequencing, DT40, DNA Helicases, Genome project, chicken genome, Gene Expression Regulation, Neoplastic, Mutagenesis, Insertional, 030220 oncology & carcinogenesis, Chickens, Gene Deletion, Reference genome
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::683bba59733bb8139c6814dac94fbec9
http://europepmc.org/articles/PMC4232548 -
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المؤلفون: D. Sinkó, Valéria Jósa, Kristóf Dede, Aron Charles Eklund, V. Szarvas, Ferenc Salamon, Marcin Krzystanek, F. Jakab, Zoltan Szallasi, Attila Marcell Szász, Zsolt Baranyai, Emese Irma Ágoston
المصدر: Thrombosis and Haemostasis. 112:483-490
مصطلحات موضوعية: Blood Platelets, Male, 0301 basic medicine, medicine.medical_specialty, Pathology, Prognostic factor, Multivariate analysis, Colorectal cancer, Gastroenterology, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Biomarkers, Tumor, Humans, Medicine, Platelet, Lymphocytes, Aged, Neoplasm Staging, Retrospective Studies, Platelet lymphocyte ratio, Thrombocytosis, Platelet Count, business.industry, Carcinoma, Liver Neoplasms, Hazard ratio, Hematology, Middle Aged, Platelet Activation, Prognosis, medicine.disease, Survival Analysis, Hepatic metastasis, digestive system diseases, 030104 developmental biology, 030220 oncology & carcinogenesis, Female, Colorectal Neoplasms, business
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::689939a6d89b00cd23c16a3fb825cea0
https://doi.org/10.1160/th13-08-0632 -
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المؤلفون: Daniel P. Silver, Aron Charles Eklund, Zhigang C. Wang, Andrea L. Richardson, Andrea Marion Marquard, Tejal Joshi, Nicolai Juul Birkbak, Zoltan Szallasi, Francesco Favero, Marcin Krzystanek
المصدر: Marquard, A M, Eklund, A C, Joshi, T, Krzystanek, M, Favero, F, Wang, Z C, Richardson, A L, Silver, D P, Szallasi, Z I & Birkbak, N J 2015, ' Pan-cancer analysis of genomic scar signatures associated with homologous recombination deficiency suggests novel indications for existing cancer drugs ', Biomarker Research, vol. 3, no. 9 . https://doi.org/10.1186/s40364-015-0033-4
Biomarker Researchمصطلحات موضوعية: endocrine system diseases, DNA repair, medicine.medical_treatment, Clinical Biochemistry, Scars, Bioinformatics, Loss of heterozygosity, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Chromosome instability, medicine, Cancer, Genomic scars, 030304 developmental biology, 0303 health sciences, Chemotherapy, business.industry, Research, Biochemistry (medical), 3. Good health, chemistry, 030220 oncology & carcinogenesis, Allelic Imbalance, Cancer research, Molecular Medicine, medicine.symptom, Homologous recombination deficiency, business, DNA, SNP array
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