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المؤلفون: Charles M. H. Hensgens, Sarah J. Lipscomb, Jack E. Baldwin, Kirsty S. Hewitson, Matthew D. Lloyd, Christopher J. Schofield
المصدر: Journal of Biological Chemistry. 279:15420-15426
مصطلحات موضوعية: Models, Molecular, Penicillin binding proteins, Stereochemistry, Iron, Molecular Sequence Data, Mutant, Streptomyces clavuligerus, Penicillins, Biochemistry, Substrate Specificity, Hydroxylation, chemistry.chemical_compound, Methionine, Penicillin-Binding Proteins, Point Mutation, Amino Acid Sequence, Cloning, Molecular, Intramolecular Transferases, Molecular Biology, chemistry.chemical_classification, Binding Sites, Sequence Homology, Amino Acid, biology, Deacetoxycephalosporin-C synthase, Tryptophan, Active site, Cell Biology, Cephalosporin C, biology.organism_classification, Streptomyces, Cephalosporins, Protein Structure, Tertiary, Acremonium, Oxygen, Kinetics, Enzyme, Models, Chemical, chemistry, Mutation, Mutagenesis, Site-Directed, Oxygenases, biology.protein, Asparagine, Protein Binding
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::734c6c04b106b5680015ac23ef2e716e
https://doi.org/10.1074/jbc.m313928200 -
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المؤلفون: Jack E. Baldwin, Karl Harlos, Inger Andersson, Ian J. Clifton, Geoffrey J. Barton, Peter L. Roach, Christopher J. Schofield, Janos Hajdu, Vilmos Fülöp
المصدر: Scopus-Elsevier
مصطلحات موضوعية: Protein Conformation, Stereochemistry, Molecular Sequence Data, Thiazolidine, Isopenicillin N synthase, Tripeptide, Crystallography, X-Ray, Aspergillus nidulans, Catalysis, chemistry.chemical_compound, Protein structure, Computer Graphics, polycyclic compounds, Amino Acid Sequence, Cloning, Molecular, Antibacterial agent, Manganese, Binding Sites, Multidisciplinary, Sequence Homology, Amino Acid, biology, Deacetoxycephalosporin-C synthase, Bicyclic molecule, Active site, Recombinant Proteins, Acremonium, chemistry, biology.protein, Oxidoreductases
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المصدر: The FEBS journal. 273(12)
مصطلحات موضوعية: Models, Molecular, Stereochemistry, Molecular Sequence Data, Hexose oxidase, Mutation, Missense, Flavin group, Biochemistry, Cofactor, Fluorescence, Chondrus, Moiety, Trypsin, Amino Acid Sequence, Molecular Biology, chemistry.chemical_classification, biology, Sequence Homology, Amino Acid, Chemistry, Acremonium strictum, Active site, Cell Biology, Hydrogen-Ion Concentration, biology.organism_classification, Alcohol Oxidoreductases, Kinetics, Enzyme, Covalent bond, biology.protein, Flavin-Adenine Dinucleotide, Sequence Alignment