المؤلفون: Yazaki T; Department of Respiratory Medicine, Japanese Red Cross Society Suwa Hospital, Suwa, Nagano, Japan.; First Department of Internal Medicine, Shinshu University School of Medicine, Matsumoto, Nagano, Japan., Kimoto M; Department of Respiratory Medicine, Japanese Red Cross Society Suwa Hospital, Suwa, Nagano, Japan., Minagawa A; Department of Respiratory Medicine, Japanese Red Cross Society Suwa Hospital, Suwa, Nagano, Japan., Maruno T; Department of Respiratory Medicine, Japanese Red Cross Society Suwa Hospital, Suwa, Nagano, Japan., Yamanaka M; Department of Respiratory Medicine, Japanese Red Cross Society Suwa Hospital, Suwa, Nagano, Japan.; First Department of Internal Medicine, Shinshu University School of Medicine, Matsumoto, Nagano, Japan., Sonehara K; First Department of Internal Medicine, Shinshu University School of Medicine, Matsumoto, Nagano, Japan., Hama M; Department of Respiratory Medicine, Japanese Red Cross Society Suwa Hospital, Suwa, Nagano, Japan., Nakamura T; Department of Diagnostic Pathology, Ina Central Hospital, Ina, Nagano, Japan., Kanda S; Department of Hematology and Medical Oncology, Shinshu University School of Medicine, Matsumoto, Nagano, Japan., Hanaoka M; First Department of Internal Medicine, Shinshu University School of Medicine, Matsumoto, Nagano, Japan., Hachiya T; Department of Respiratory Medicine, Japanese Red Cross Society Suwa Hospital, Suwa, Nagano, Japan.

المصدر: The American journal of case reports [Am J Case Rep] 2024 Jun 01; Vol. 25, pp. e943466. Date of Electronic Publication: 2024 Jun 01.

نوع المنشور: Case Reports; Journal Article

بيانات الدورية: Publisher: International Scientific Information, Inc Country of Publication: United States NLM ID: 101489566 Publication Model: Electronic Cited Medium: Internet ISSN: 1941-5923 (Electronic) Linking ISSN: 19415923 NLM ISO Abbreviation: Am J Case Rep Subsets: MEDLINE

مواضيع طبية MeSH: Adenocarcinoma*/drug therapy , Adenocarcinoma*/genetics , Adenocarcinoma of Lung*/drug therapy , Adenocarcinoma of Lung*/genetics , ErbB Receptors*/genetics , Erlotinib Hydrochloride*/therapeutic use , Lung Neoplasms*/drug therapy , Lung Neoplasms*/genetics , Lung Neoplasms*/pathology , Small Cell Lung Carcinoma*/genetics , Small Cell Lung Carcinoma*/drug therapy , Small Cell Lung Carcinoma*/pathology, Aged ; Humans ; Male ; Drug Resistance, Neoplasm ; Mutation ; Tyrosine Kinase Inhibitors/therapeutic use

المؤلفون: Fujimoto K; Department of Respiratory Medicine, Kanagawa Cardiovascular and Respiratory Center, 6-16-1 Tomioka-higashi, Kanazawa-ku, Yokohama-city, Kanagawa, 236-0051, Japan. Electronic address: fujimoto.8x50n@kanagawa-pho.jp., Sekine A; Department of Respiratory Medicine, Kanagawa Cardiovascular and Respiratory Center, 6-16-1 Tomioka-higashi, Kanazawa-ku, Yokohama-city, Kanagawa, 236-0051, Japan., Hagiwara E; Department of Respiratory Medicine, Kanagawa Cardiovascular and Respiratory Center, 6-16-1 Tomioka-higashi, Kanazawa-ku, Yokohama-city, Kanagawa, 236-0051, Japan., Asaoka M; Department of Respiratory Medicine, Kanagawa Cardiovascular and Respiratory Center, 6-16-1 Tomioka-higashi, Kanazawa-ku, Yokohama-city, Kanagawa, 236-0051, Japan., Ikeda S; Department of Respiratory Medicine, Kanagawa Cardiovascular and Respiratory Center, 6-16-1 Tomioka-higashi, Kanazawa-ku, Yokohama-city, Kanagawa, 236-0051, Japan., Baba T; Department of Respiratory Medicine, Kanagawa Cardiovascular and Respiratory Center, 6-16-1 Tomioka-higashi, Kanazawa-ku, Yokohama-city, Kanagawa, 236-0051, Japan., Komatsu S; Department of Respiratory Medicine, Kanagawa Cardiovascular and Respiratory Center, 6-16-1 Tomioka-higashi, Kanazawa-ku, Yokohama-city, Kanagawa, 236-0051, Japan., Ogura T; Department of Respiratory Medicine, Kanagawa Cardiovascular and Respiratory Center, 6-16-1 Tomioka-higashi, Kanazawa-ku, Yokohama-city, Kanagawa, 236-0051, Japan.

المصدر: Respiratory investigation [Respir Investig] 2024 May; Vol. 62 (3), pp. 360-364. Date of Electronic Publication: 2024 Feb 29.

نوع المنشور: Observational Study; Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101581124 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2212-5353 (Electronic) Linking ISSN: 22125345 NLM ISO Abbreviation: Respir Investig Subsets: MEDLINE

مواضيع طبية MeSH: Carcinoma, Non-Small-Cell Lung*/drug therapy , Lung Neoplasms*/pathology , Adenocarcinoma*/drug therapy , Adenocarcinoma, Mucinous*/drug therapy , Adenocarcinoma, Mucinous*/chemically induced, Humans ; Bevacizumab ; Retrospective Studies ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Neoplasm Recurrence, Local/drug therapy ; Lung/pathology

المؤلفون: Akcam TI; Department of Thoracic Surgery, Ege University School of Medicine, İzmir, Turkey., Tekneci AK; Department of Thoracic Surgery, Health Sciences University İzmir Tepecik Education and Research Hospital, İzmir, Turkey., Ergin TM; Department of Thoracic Surgery, Ege University School of Medicine, İzmir, Turkey., Memmedov R; Department of Thoracic Surgery, Ege University School of Medicine, İzmir, Turkey., Ergonul AG; Department of Thoracic Surgery, Ege University School of Medicine, İzmir, Turkey., Ozdil A; Department of Thoracic Surgery, Ege University School of Medicine, İzmir, Turkey., Turhan K; Department of Thoracic Surgery, Ege University School of Medicine, İzmir, Turkey., Cakan A; Department of Thoracic Surgery, Ege University School of Medicine, İzmir, Turkey., Cagırıcı U; Department of Thoracic Surgery, Ege University School of Medicine, İzmir, Turkey.

المصدر: Acta chirurgica Belgica [Acta Chir Belg] 2024 Apr; Vol. 124 (2), pp. 121-130. Date of Electronic Publication: 2023 Jul 05.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Taylor & Francis Country of Publication: England NLM ID: 0370571 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 0001-5458 (Print) Linking ISSN: 00015458 NLM ISO Abbreviation: Acta Chir Belg Subsets: MEDLINE

مواضيع طبية MeSH: Carcinoma, Non-Small-Cell Lung*/surgery , Carcinoma, Non-Small-Cell Lung*/pathology , Lung Neoplasms* , Adenocarcinoma*/pathology , Carcinoma, Squamous Cell*/surgery , Carcinoma, Squamous Cell*/pathology, Humans ; Retrospective Studies ; Neoplasm Staging ; Prognosis ; Neoplasm Recurrence, Local/pathology ; Neoplasm Invasiveness/pathology

المؤلفون: Agaoglu Sanli B; Dr Suat Seren Chest Diseases and Chest Surgery Training and Research Hospital, University of Health Sciences Turkey, Izmir, Turkey. drbaharagaoglu@hotmail.com., Gulmez B; Van Training and Research Hospital, Thoracic Surgery Clinic, University of Health Sciences Turkey, Van, Turkey., Yazgan S; Dr Suat Seren Chest Diseases and Chest Surgery Training and Research Hospital, University of Health Sciences Turkey, Izmir, Turkey., Ucvet A; Dr Suat Seren Chest Diseases and Chest Surgery Training and Research Hospital, University of Health Sciences Turkey, Izmir, Turkey.

المصدر: Updates in surgery [Updates Surg] 2024 Apr; Vol. 76 (2), pp. 631-639. Date of Electronic Publication: 2023 Oct 18.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Springer-Verlag Italia Country of Publication: Italy NLM ID: 101539818 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2038-3312 (Electronic) Linking ISSN: 2038131X NLM ISO Abbreviation: Updates Surg Subsets: MEDLINE

مواضيع طبية MeSH: Carcinoma, Non-Small-Cell Lung*/surgery , Carcinoma, Non-Small-Cell Lung*/pathology , Lung Neoplasms*/surgery , Lung Neoplasms*/pathology , Adenocarcinoma*/pathology , Carcinoma, Squamous Cell*/surgery, Humans ; Prognosis ; Retrospective Studies ; Lymphocytes/metabolism ; C-Reactive Protein ; Biomarkers, Tumor

المؤلفون: Charkiewicz R; Center of Experimental Medicine, Medical University of Bialystok, 15-369 Bialystok, Poland.; Department of Clinical Molecular Biology, Medical University of Bialystok, 15-269 Bialystok, Poland., Sulewska A; Department of Clinical Molecular Biology, Medical University of Bialystok, 15-269 Bialystok, Poland., Karabowicz P; Biobank, Medical University of Bialystok, 15-269 Bialystok, Poland., Lapuc G; Department of Thoracic Surgery, Medical University of Bialystok, 15-269 Bialystok, Poland., Charkiewicz A; Department of Analysis and Bioanalysis of Medicines, Medical University of Bialystok, 15-089 Bialystok, Poland., Kraska M; Department of Clinical Molecular Biology, Medical University of Bialystok, 15-269 Bialystok, Poland.; Department of Medical Pathomorphology, Medical University of Bialystok, 15-269 Bialystok, Poland., Pancewicz J; Department of Histology and Embryology, Medical University of Bialystok, 15-269 Bialystok, Poland., Lukasik M; Department of Histology and Embryology, Medical University of Bialystok, 15-269 Bialystok, Poland., Kozlowski M; Department of Thoracic Surgery, Medical University of Bialystok, 15-269 Bialystok, Poland., Stec R; Department of Oncology, Medical University of Warsaw, 02-091 Warsaw, Poland., Ziembicka D; Department of Public Health, Medical University of Bialystok, 15-295 Bialystok, Poland., Piszcz W; Department of Clinical Molecular Biology, Medical University of Bialystok, 15-269 Bialystok, Poland., Miltyk W; Department of Analysis and Bioanalysis of Medicines, Medical University of Bialystok, 15-089 Bialystok, Poland., Niklinska W; Department of Histology and Embryology, Medical University of Bialystok, 15-269 Bialystok, Poland.

المصدر: International journal of molecular sciences [Int J Mol Sci] 2024 Mar 23; Vol. 25 (7). Date of Electronic Publication: 2024 Mar 23.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Carcinoma, Non-Small-Cell Lung*/diagnosis , Carcinoma, Non-Small-Cell Lung*/genetics , Carcinoma, Non-Small-Cell Lung*/therapy , Lung Neoplasms*/diagnosis , Lung Neoplasms*/genetics , Lung Neoplasms*/therapy , Adenocarcinoma* , Carcinoma, Squamous Cell*/diagnosis , Carcinoma, Squamous Cell*/genetics , Carcinoma, Squamous Cell*/therapy , Small Cell Lung Carcinoma*, Humans ; Diagnosis, Differential

المؤلفون: Dwivedi K; Department of Computer Science, University of Delhi, Delhi, India. Electronic address: kountaydwivedi@gmail.com., Rajpal A; Department of Computer Science, University of Delhi, Delhi, India. Electronic address: arajpal@cs.du.ac.in., Rajpal S; Department of Computer Science, Dyal Singh College, Delhi, India. Electronic address: sheetal.rajpal.09@gmail.com., Kumar V; Department of Nuclear Magnetic Resonance, All India Institute of Medical Sciences, New Delhi, India. Electronic address: virendrakumar@aiims.edu., Agarwal M; Department of Computer Science, Hans Raj College, University of Delhi, Delhi, India. Electronic address: agar.manoj@gmail.com., Kumar N; Department of Computer Science, University of Delhi, Delhi, India. Electronic address: nk.cs.du@gmail.com.

المصدر: Computational biology and chemistry [Comput Biol Chem] 2024 Feb; Vol. 108, pp. 107990. Date of Electronic Publication: 2023 Nov 23.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: England NLM ID: 101157394 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-928X (Electronic) Linking ISSN: 14769271 NLM ISO Abbreviation: Comput Biol Chem Subsets: MEDLINE

مواضيع طبية MeSH: Carcinoma, Non-Small-Cell Lung*/diagnosis , Carcinoma, Non-Small-Cell Lung*/genetics , Lung Neoplasms*/diagnosis , Lung Neoplasms*/genetics , Adenocarcinoma*, Humans ; DNA Copy Number Variations ; Biomarkers

المؤلفون: Shigeta N; Department of Thoracic Surgery, Kanagawa Cancer Center, Yokohama, Japan., Yokose T; Department of Pathology, Kanagawa Cancer Center, Yokohama, Japan., Murakami S; Department of Thoracic Oncology, Kanagawa Cancer Center, Yokohama, Japan., Isaka T; Department of Thoracic Surgery, Kanagawa Cancer Center, Yokohama, Japan., Shinada K; Department of Thoracic Oncology, Kanagawa Cancer Center, Yokohama, Japan., Yoshioka E; Department of Pathology, Kanagawa Cancer Center, Yokohama, Japan., Narita A; Department of Thoracic Oncology, Kanagawa Cancer Center, Yokohama, Japan., Katakura K; Department of Thoracic Oncology, Kanagawa Cancer Center, Yokohama, Japan., Kondo T; Department of Thoracic Oncology, Kanagawa Cancer Center, Yokohama, Japan., Kato T; Department of Thoracic Oncology, Kanagawa Cancer Center, Yokohama, Japan., Nagashima T; Department of Thoracic Surgery, Kanagawa Cancer Center, Yokohama, Japan., Saito H; Department of Thoracic Oncology, Kanagawa Cancer Center, Yokohama, Japan., Ito H; Department of Thoracic Surgery, Kanagawa Cancer Center, Yokohama, Japan.

المصدر: Thoracic cancer [Thorac Cancer] 2024 Feb; Vol. 15 (6), pp. 458-465. Date of Electronic Publication: 2024 Jan 10.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley Publishing Asia Pty Ltd Country of Publication: Singapore NLM ID: 101531441 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1759-7714 (Electronic) Linking ISSN: 17597706 NLM ISO Abbreviation: Thorac Cancer Subsets: MEDLINE

مواضيع طبية MeSH: Adenocarcinoma*/diagnosis , Adenocarcinoma*/genetics , Adenocarcinoma*/metabolism , Carcinoma, Non-Small-Cell Lung*/diagnosis , Carcinoma, Non-Small-Cell Lung*/genetics , Carcinoma, Non-Small-Cell Lung*/metabolism , Carcinoma, Squamous Cell*/diagnosis , Carcinoma, Squamous Cell*/genetics , Carcinoma, Squamous Cell*/metabolism , Lung Neoplasms*/diagnosis , Lung Neoplasms*/genetics , Lung Neoplasms*/metabolism, Humans ; B7-H1 Antigen/genetics ; B7-H1 Antigen/metabolism ; ErbB Receptors/genetics ; Mutation

المؤلفون: Ruiz G; Pathology & Molecular Biology Laboratories, Biomakers, Buenos Aires, Argentina., Enrico D; Thoracic Oncology Unit, Department of Medical Oncology, Alexander Fleming Cancer Institute, Buenos Aires, Argentina.; Clinical Research Unit, Department of Medical Oncology, Alexander Fleming Cancer Institute, Buenos Aires, Argentina., Mahmoud YD; Universidad Argentina de la Empresa (UADE), Instituto de Tecnología (INTEC), Buenos Aires, Argentina.; Laboratorio de Glicomedicina, Instituto de Biología y Medicina Experimental (IBYME), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Buenos Aires, Argentina., Ruiz A; Pathology & Molecular Biology Laboratories, Biomakers, Buenos Aires, Argentina., Cantarella MF; Pathology & Molecular Biology Laboratories, Biomakers, Buenos Aires, Argentina., Leguina L; Pathology & Molecular Biology Laboratories, Biomakers, Buenos Aires, Argentina., Barberis M; Pathology & Molecular Biology Laboratories, Biomakers, Buenos Aires, Argentina., Beña A; Pathology & Molecular Biology Laboratories, Biomakers, Buenos Aires, Argentina., Brest E; Pathology & Molecular Biology Laboratories, Biomakers, Buenos Aires, Argentina., Starapoli S; Pathology & Molecular Biology Laboratories, Biomakers, Buenos Aires, Argentina., Mendoza Bertelli A; Pathology & Molecular Biology Laboratories, Biomakers, Buenos Aires, Argentina., Tsou F; Thoracic Oncology Unit, Department of Medical Oncology, Alexander Fleming Cancer Institute, Buenos Aires, Argentina.; Clinical Research Unit, Department of Medical Oncology, Alexander Fleming Cancer Institute, Buenos Aires, Argentina., Pupareli C; Thoracic Oncology Unit, Department of Medical Oncology, Alexander Fleming Cancer Institute, Buenos Aires, Argentina.; Clinical Research Unit, Department of Medical Oncology, Alexander Fleming Cancer Institute, Buenos Aires, Argentina., Coppola MP; Medical Oncology Unit, Hospital Zonal Especializado en Agudos y Crónicos Dr. Antonio Cetrangolo, Buenos Aires, Argentina., Scocimarro A; Medical Oncology Unit, Hospital Zonal Especializado en Agudos y Crónicos Dr. Antonio Cetrangolo, Buenos Aires, Argentina., Sena S; Medical Oncology Department, Hospital Alemán, Buenos Aires, Argentina., Levit P; Medical Oncology Unit, Unión Personal-Accord Salud, Buenos Aires, Argentina., Perfetti A; Medical Oncology Unit, Unión Personal-Accord Salud, Buenos Aires, Argentina.; Medical Oncology Department, Centro de Educación Médica e Investigaciones Clínicas (CEMIC), Buenos Aires, Argentina., Aman E; Medical Oncology Unit, Swiss Medical Group, Buenos Aires, Argentina., Girotti MR; Pathology & Molecular Biology Laboratories, Biomakers, Buenos Aires, Argentina.; Universidad Argentina de la Empresa (UADE), Instituto de Tecnología (INTEC), Buenos Aires, Argentina., Arrieta O; Head of Thoracic Oncology Unit, Unidad Funcional de Oncología Torácica, Instituto Nacional de Cancerología (INCan), Mexico City, Mexico., Martín C; Thoracic Oncology Unit, Department of Medical Oncology, Alexander Fleming Cancer Institute, Buenos Aires, Argentina.; Clinical Research Unit, Department of Medical Oncology, Alexander Fleming Cancer Institute, Buenos Aires, Argentina., Salanova R; Pathology & Molecular Biology Laboratories, Biomakers, Buenos Aires, Argentina.

المصدر: Thoracic cancer [Thorac Cancer] 2024 Apr; Vol. 15 (11), pp. 895-905. Date of Electronic Publication: 2024 Mar 08.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley Publishing Asia Pty Ltd Country of Publication: Singapore NLM ID: 101531441 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1759-7714 (Electronic) Linking ISSN: 17597706 NLM ISO Abbreviation: Thorac Cancer Subsets: MEDLINE

مواضيع طبية MeSH: Carcinoma, Non-Small-Cell Lung*/pathology , Lung Neoplasms*/pathology , Adenocarcinoma*/genetics, Male ; Humans ; Protein-Tyrosine Kinases/genetics ; B7-H1 Antigen/genetics ; B7-H1 Antigen/metabolism ; Retrospective Studies ; Anaplastic Lymphoma Kinase/genetics ; Proto-Oncogene Proteins/genetics ; Mutation ; ErbB Receptors/genetics

المؤلفون: Lee J; Lung Cancer Center, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Korea., Ahn HK; Department of Medical Oncology, Gachon University Gil Medical Center, Incheon, Korea., Kim SW; Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea., Han JY; Center for Lung Cancer, National Cancer Center, Research Institute and Hospital, Goyang, Korea., Lee SS; Department of Hematology-Oncology, Inje University Haeundae Paik Hospital, Busan, Korea., Park HS; Division of Medical Oncology, Department of Internal Medicine, St. Vincent's Hospital, The Catholic University of Korea, Suwon, Korea., Lee HW; Department of Hematology-Oncology, Ajou University School of Medicine, Suwon, Korea., Kim JH; CHA Bundang Medical Center, CHA University, Seongnam, Korea., Cho E; AstraZeneca, Seoul, Korea., Huggenberger R; AstraZeneca, Baar, Switzerland., Cho BC; Lung Cancer Center, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Korea.

المصدر: Cancer medicine [Cancer Med] 2024 Apr; Vol. 13 (7), pp. e7174.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: John Wiley & Sons Ltd Country of Publication: United States NLM ID: 101595310 Publication Model: Print Cited Medium: Internet ISSN: 2045-7634 (Electronic) Linking ISSN: 20457634 NLM ISO Abbreviation: Cancer Med Subsets: MEDLINE

مواضيع طبية MeSH: Carcinoma, Non-Small-Cell Lung*/genetics , Carcinoma, Non-Small-Cell Lung*/therapy , Lung Neoplasms*/genetics , Lung Neoplasms*/therapy , Adenocarcinoma*, Male ; Humans ; Aged ; Female ; Chemoradiotherapy ; Republic of Korea/epidemiology ; Retrospective Studies

المؤلفون: Gálffy G; Pulmonology Hospital Törökbálint, Törökbálint, Hungary., Morócz É; Pulmonology Hospital Törökbálint, Törökbálint, Hungary., Korompay R; Pulmonology Hospital Törökbálint, Törökbálint, Hungary., Hécz R; Pulmonology Hospital Törökbálint, Törökbálint, Hungary., Bujdosó R; Pulmonology Hospital Törökbálint, Törökbálint, Hungary., Puskás R; Pulmonology Hospital Törökbálint, Törökbálint, Hungary., Lovas T; Pulmonology Hospital Törökbálint, Törökbálint, Hungary., Gáspár E; Pulmonology Hospital Törökbálint, Törökbálint, Hungary., Yahya K; Pulmonology Hospital Törökbálint, Törökbálint, Hungary., Király P; Pulmonology Hospital Törökbálint, Törökbálint, Hungary., Lohinai Z; Pulmonology Hospital Törökbálint, Törökbálint, Hungary.

المصدر: Pathology oncology research : POR [Pathol Oncol Res] 2024 Mar 28; Vol. 30, pp. 1611715. Date of Electronic Publication: 2024 Mar 28 (Print Publication: 2024).

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Frontiers Media S. A Country of Publication: Switzerland NLM ID: 9706087 Publication Model: eCollection Cited Medium: Internet ISSN: 1532-2807 (Electronic) Linking ISSN: 12194956 NLM ISO Abbreviation: Pathol Oncol Res Subsets: MEDLINE

مواضيع طبية MeSH: Carcinoma, Non-Small-Cell Lung*/drug therapy , Carcinoma, Non-Small-Cell Lung*/genetics , Carcinoma, Non-Small-Cell Lung*/pathology , Lung Neoplasms*/drug therapy , Lung Neoplasms*/genetics , Lung Neoplasms*/pathology , Adenocarcinoma of Lung* , Adenocarcinoma*/genetics , Acetonitriles* , Piperazines* , Pyrimidines*, Humans ; Protein-Tyrosine Kinases/genetics ; Proto-Oncogene Proteins p21(ras)/genetics ; Proto-Oncogene Proteins/genetics ; Mutation ; ErbB Receptors/genetics