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المؤلفون: Richard S. Finn, Zhenggang Ren, Corina E. Dutcus, Masahiro Kobayashi, Ann-Lii Cheng, Masatoshi Kudo, Jung Hwan Yoon, Minshan Chen, Fabio Piscaglia, Kalgi Mody, Kenji Ikeda, Min Ren, Max W. Sung, Shukui Qin, Toshiyuki Tamai, Hiromitsu Kumada, Lucjan Wyrwicz, Kwang Hyub Han, Seiichi Hayato, Takuji Okusaka
المساهمون: Okusaka T., Ikeda K., Kudo M., Finn R., Qin S., Han K.-H., Cheng A.-L., Piscaglia F., Kobayashi M., Sung M., Chen M., Wyrwicz L., Yoon J.-H., Ren Z., Mody K., Dutcus C., Tamai T., Ren M., Hayato S., Kumada H.
المصدر: Journal of Gastroenterology
مصطلحات موضوعية: Adult, Male, Sorafenib, medicine.medical_specialty, Carcinoma, Hepatocellular, Hepatocellular carcinoma, Phases of clinical research, Antineoplastic Agents, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Internal medicine, Post-hoc analysis, medicine, Humans, Lenvatinib, Dosing, Adverse effect, Aged, Aged, 80 and over, Original Article—Liver, Pancreas, and Biliary Tract, Dose-Response Relationship, Drug, business.industry, Phenylurea Compounds, Liver Neoplasms, Gastroenterology, Middle Aged, Body weight, medicine.disease, Confidence interval, Treatment Outcome, chemistry, 030220 oncology & carcinogenesis, Quinolines, Female, REFLECT, 030211 gastroenterology & hepatology, business, medicine.drug
وصف الملف: STAMPA
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المؤلفون: Philip He, Robin Kate Kelley, Ho Yeong Lim, Takuji Okusaka, Thomas Yau, David Wai-Meng Tai, Ghassan K. Abou-Alfa, Masafumi Ikeda, Bruno Sangro, Yoon-Koo Kang, Silvia Damian, Johanna C. Bendell, Mitesh J. Borad, William P. Harris, Tae-You Kim, Shukui Qin, Alejandra Negro, Mallory Makowsky, Nathan Standifer, Masatoshi Kudo, Ann-Lii Cheng, Jordi Bruix, Antonio Gasbarrini, Wei Peng Yong
المصدر: Journal of clinical oncology : official journal of the American Society of Clinical Oncology, vol 39, iss 27
مصطلحات موضوعية: Male, 0301 basic medicine, Oncology, Cancer Research, Durvalumab, 0302 clinical medicine, Monoclonal, 80 and over, Humanized, 6.2 Cellular and gene therapies, Cancer, Aged, 80 and over, Liver Disease, Liver Neoplasms, Middle Aged, 6.1 Pharmaceuticals, 030220 oncology & carcinogenesis, Hepatocellular carcinoma, HIV/AIDS, Female, Patient Safety, Biotechnology, medicine.drug, Liver Cancer, Adult, medicine.medical_specialty, Carcinoma, Hepatocellular, medicine.drug_class, Clinical Trials and Supportive Activities, Clinical Sciences, Oncology and Carcinogenesis, Antibodies, Monoclonal, Humanized, Monoclonal antibody, Antibodies, 03 medical and health sciences, Rare Diseases, Clinical Research, Internal medicine, medicine, Humans, Oncology & Carcinogenesis, Aged, business.industry, Carcinoma, Evaluation of treatments and therapeutic interventions, Hepatocellular, medicine.disease, Orphan Drug, 030104 developmental biology, Phase i ii, Pharmacodynamics, Digestive Diseases, business, Tremelimumab
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::140a2fcc92ec29522c1c3fd8efbcf87a
https://doi.org/10.1200/jco.20.03555 -
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المؤلفون: Misato Tsubokura, Yuko Adegawa, Minoru Kojima, Ryuji Tanosaki, Ryuzaburo Ohtake, Yuki Kase, Nao Iwashita, Moemi Kasane, Saori Nakabayashi, Sayaka Takeuchi, Ken Kato, Narikazu Boku, Yukihide Kanemitsu, Takuji Okusaka, Hiroyuki Fujimoto, Kan Yonemori, Hiroto Ishiki, Kimihiko Kawamura, Eriko Satomi, Hiromichi Matsushita
المصدر: BMC Cancer. 22
مصطلحات موضوعية: Adult, Aged, 80 and over, Male, Cancer Research, Cell-Free System, Cell- and Tissue-Based Therapy, Ascites, Middle Aged, Digestive System Neoplasms, Cross-Sectional Studies, Treatment Outcome, Oncology, Genetics, Humans, Female, Infusions, Parenteral, Aged, Retrospective Studies
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المؤلفون: Masatoshi, Kudo, Kazuomi, Ueshima, Masafumi, Ikeda, Takuji, Torimura, Nobukazu, Tanabe, Hiroshi, Aikata, Namiki, Izumi, Takahiro, Yamasaki, Shunsuke, Nojiri, Keisuke, Hino, Hidetaka, Tsumura, Teiji, Kuzuya, Norio, Isoda, Kohichiroh, Yasui, Hajime, Aino, Akio, Ido, Naoto, Kawabe, Kazuhiko, Nakao, Yoshiyuki, Wada, Osamu, Yokosuka, Kenichi, Yoshimura, Takuji, Okusaka, Junji, Furuse, Norihiro, Kokudo, Kiwamu, Okita, Philip James, Johnson, Yasuaki, Arai, Manabu, Morimoto
المصدر: Gut
Ann Transl Medمصطلحات موضوعية: Sorafenib, Adult, Male, medicine.medical_specialty, Carcinoma, Hepatocellular, Antineoplastic Agents, transarterial chemoembolization, Gastroenterology, combination therapy with transarterial chemoembolisation and sorafenib, Internal medicine, medicine, Humans, In patient, Progression-free survival, Prospective Studies, Chemoembolization, Therapeutic, Adverse effect, Trial registration, neoplasms, Cause of death, Aged, Aged, 80 and over, Hepatology, business.industry, Liver Neoplasms, hepatocellular carcinoma, Middle Aged, medicine.disease, Combined Modality Therapy, digestive system diseases, Survival Rate, Editorial Commentary, Prospective trial, Hepatocellular carcinoma, Disease Progression, Female, sorafenib, business, progression-free survival, medicine.drug
وصف الملف: application/pdf
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المؤلفون: Junji Furuse, Kazuhiko Shioji, Hiroyuki Okuyama, Masayuki Furukawa, Motohiro Kojima, Hiroki Hara, Shinichi Ohkawa, Takuji Okusaka, Masafumi Ikeda, Yasushi Kojima, Ayumu Hosokawa, Takeharu Yamanaka, Akinori Asagi, Nobumasa Mizuno, Gou Murohisa
المصدر: Neuroendocrinology. 110:988-993
مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Drug-Related Side Effects and Adverse Reactions, Anemia, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Antineoplastic Agents, Gastroenterology, Cellular and Molecular Neuroscience, Endocrinology, Refractory, Internal medicine, Outcome Assessment, Health Care, Clinical endpoint, Humans, Medicine, Everolimus, Prospective Studies, Adverse effect, Aged, Platinum, Aged, 80 and over, Chemotherapy, Endocrine and Autonomic Systems, business.industry, Middle Aged, medicine.disease, Progression-Free Survival, Confidence interval, Carcinoma, Neuroendocrine, Pancreatic Neoplasms, Toxicity, Female, business, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3430a3068f1ae750aa5ad1f78f62a4f
https://doi.org/10.1159/000505550 -
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المؤلفون: Hiroshi Aikata, Masahiro Kobayashi, Yasunori Kawaguchi, Kenji Ikeda, Tatsuya Yamashita, Kenichi Saito, Ryosuke Tateishi, Masatoshi Kudo, Chifumi Kitamura, Masafumi Ikeda, Takuji Okusaka, Ryoko Kuromatsu, Kazushi Numata, Yoshiyuki Wada, Hiromitsu Kumada, Katsuya Haruna, Yoshitaka Inaba, Toshiyuki Tamai, Namiki Izumi, Kiwamu Okita
المصدر: Journal of Gastroenterology
مصطلحات موضوعية: Adult, Male, Subset Analysis, Oncology, Sorafenib, medicine.medical_specialty, Carcinoma, Hepatocellular, Hepatocellular carcinoma, Population, Antineoplastic Agents, chemistry.chemical_compound, Japan, Internal medicine, medicine, Humans, Lenvatinib, Adverse effect, education, Aged, Aged, 80 and over, Original Article—Liver, Pancreas, and Biliary Tract, education.field_of_study, Japanese population, business.industry, Phenylurea Compounds, Liver Neoplasms, Hazard ratio, REFLECT trial, Gastroenterology, Middle Aged, medicine.disease, Survival Analysis, Confidence interval, Intention to Treat Analysis, Treatment Outcome, chemistry, Quinolines, Female, business, medicine.drug
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المؤلفون: Chigusa Morizane, Ken Ohashi, Mitsuhito Sasaki, Hideki Ueno, Yasunari Sakamoto, Shuichi Mitsunaga, Hideaki Takahashi, Shunsuke Kondo, Hiroshi Imaoka, Aya Kuchiba, Masafumi Ikeda, Takuji Okusaka, Izumi Ohno, Sakura Iizumi, Keiichiro Osame, Yusuke Hashimoto
المصدر: Internal Medicine
مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Time Factors, medicine.medical_treatment, pancreatic cancer, 030204 cardiovascular system & hematology, chemotherapy, Gastroenterology, Deoxycytidine, 03 medical and health sciences, 0302 clinical medicine, Japan, Diabetes mellitus, Pancreatic cancer, Internal medicine, Internal Medicine, medicine, Brief Psychiatric Rating Scale, Humans, Aged, Proportional Hazards Models, Retrospective Studies, Aged, 80 and over, Chemotherapy, business.industry, Medical record, Hazard ratio, gemcitabine, Retrospective cohort study, General Medicine, Middle Aged, medicine.disease, Prognosis, Confidence interval, Gemcitabine, Pancreatic Neoplasms, Treatment Outcome, diabetes mellitus, 030211 gastroenterology & hepatology, Original Article, Female, business, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::462862496777e2928ea7eb626bebeb4a
http://europepmc.org/articles/PMC6761348 -
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المؤلفون: Josep M. Llovet, Kenichi Saito, Ari David Baron, Abby B. Siegel, Andrew X. Zhu, Corina E. Dutcus, Leonid Dubrovsky, Hiromitsu Kumada, Masatoshi Kudo, Marc Pracht, Masafumi Ikeda, Tim Meyer, Kalgi Mody, Richard S. Finn, Tomoki Kubota, Shuichi Kaneko, Konstantin Mamontov, Takuji Okusaka, Max W. Sung, Masahiro Kobayashi
المصدر: Dipòsit Digital de la UB
Universidad de Barcelona
Journal of Clinical Oncologyمصطلحات موضوعية: 0301 basic medicine, Male, Cancer Research, Carcinoma, Hepatocellular, Time Factors, Immunoglobulins, Pembrolizumab, Antibodies, Monoclonal, Humanized, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Antineoplastic Combined Chemotherapy Protocols, RAPID COMMUNICATIONS, Gastrointestinal Cancer, Carcinoma, medicine, Humans, In patient, Progression-free survival, Aged, Neoplasm Staging, Tumors, Aged, 80 and over, Tumor microenvironment, business.industry, Phenylurea Compounds, Liver Neoplasms, Drugs, Middle Aged, medicine.disease, Progression-Free Survival, 030104 developmental biology, Oncology, chemistry, 030220 oncology & carcinogenesis, Hepatocellular carcinoma, Monoclonal, Cancer research, Disease Progression, Quinolines, Female, business, Lenvatinib, Immunoglobulines, Medicaments
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::729a5a82722d30c6703fd1a1743749b5
http://hdl.handle.net/2445/174833 -
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المؤلفون: Dufour, Jean-François, Schwartz, Jonathan D, Zhu, Andrew X, Pastorelli, Davide, Chau, Ian, REACH Trial, Investigators., Chang, Shao-Chun, Okusaka, Takuji, Ryoo, Baek-Yeol, Chung, Hyun Cheol, Blanc, Jean-Frederic, Trojan, Jorg, Sastre, Javier, Kubackova, Katerina, Abada, Paolo B, Yen, Chia-Jui, Yang, Ling, Pfiffer, Tulio Eduardo Flesch, Kudo, Masatoshi, Baron, Ari D, Poon, Ronnie, Park, Joon Oh
المساهمون: Zhu AX, Park JO, Ryoo BY, Yen CJ, Poon R, Pastorelli D, Blanc JF, Chung HC, Baron AD, Pfiffer TE, Okusaka T, Kubackova K, Trojan J, Sastre J, Chau I, Chang SC, Abada PB, Yang L, Schwartz JD, Kudo M, REACH Trial Investigator, Brandi G., Zhu A.X., Park J.O., Ryoo B.-Y., Yen C.-J., Poon R., Pastorelli D., Blanc J.-F., Chung H.C., Baron A.D., Pfiffer T.E.F., Okusaka T., Kubackova K., Trojan J., Sastre J., Chau I., Chang S.-C., Abada P.B., Yang L., Schwartz J.D., Kudo M., Craxì Antonio.
المصدر: The Lancet Oncology. 16:859-870
مصطلحات موضوعية: Male, Time Factors, Kaplan-Meier Estimate, Gastroenterology, Liver disease, Clinical endpoint, 610 Medicine & health, ramucirumab, sorafenib, HCC, Aged, 80 and over, education.field_of_study, Liver Neoplasms, Remission Induction, Antibodies, Monoclonal, Middle Aged, Sorafenib, Treatment Outcome, Oncology, Liver Neoplasm, Hepatocellular carcinoma, Female, Survival Analysi, Human, medicine.drug, Adult, Niacinamide, Phenylurea Compound, medicine.medical_specialty, Carcinoma, Hepatocellular, Time Factor, Population, Antibodies, Monoclonal, Humanized, Placebo, Disease-Free Survival, Drug Administration Schedule, Follow-Up Studie, Ramucirumab, Double-Blind Method, Internal medicine, Confidence Intervals, medicine, Carcinoma, Humans, education, Proportional Hazards Models, Aged, Dose-Response Relationship, Drug, business.industry, Phenylurea Compounds, Patient Selection, medicine.disease, Survival Analysis, digestive system diseases, Surgery, Proportional Hazards Model, business, Confidence Interval, Follow-Up Studies
وصف الملف: STAMPA
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المؤلفون: Mikiro Kobayashi, Hideaki Takahashi, Shelby A. Gorman, Akiko Todaka, Masafumi Ikeda, Chigusa Morizane, Takuji Okusaka, Daniel J. Felitsky, Akiyoshi Kasuga, Akira Fukutomi, Junji Furuse, Tatsuya Ioka, Fanghong Zhang, Caretha L. Creasy
المصدر: Cancer Science
مصطلحات موضوعية: Male, 0301 basic medicine, Cancer Research, Administration, Oral, Gastroenterology, 0302 clinical medicine, Aged, 80 and over, Trametinib, trametinib, Neurofibromin 1, MEK inhibitor, gemcitabine, Ampulla of Vater, Nuclear Proteins, General Medicine, Middle Aged, 3. Good health, DNA-Binding Proteins, Biliary Tract Neoplasms, Treatment Outcome, medicine.anatomical_structure, Oncology, Biliary tract, 030220 oncology & carcinogenesis, Original Article, Female, Gallbladder Neoplasms, medicine.drug, medicine.medical_specialty, Pyridones, Pyrimidinones, 03 medical and health sciences, Clinical Research, biliary tract cancer, Internal medicine, Exome Sequencing, medicine, Carcinoma, Humans, Protein Kinase Inhibitors, Survival analysis, Aged, business.industry, Original Articles, medicine.disease, Survival Analysis, Gemcitabine, Surgery, refractory, 030104 developmental biology, Bile Duct Neoplasms, business, Progressive disease, Transcription Factors
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