المؤلفون: Yan Y; Genetics and Genomics Graduate Program, University of Florida, Gainesville, Florida, United States of America ; Department of Pharmacology and Therapeutics, University of Florida, Gainesville, Florida, United States of America ; Genetics Institute, University of Florida, Gainesville, Florida, United States of America., Salazar TE, Dominguez JM 2nd, Nguyen DV, Li Calzi S, Bhatwadekar AD, Qi X, Busik JV, Boulton ME, Grant MB

المصدر: PloS one [PLoS One] 2013 Nov 07; Vol. 8 (11), pp. e80029. Date of Electronic Publication: 2013 Nov 07 (Print Publication: 2013).

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

مواضيع طبية MeSH: Aging/*genetics , DEAD-box RNA Helicases/*genetics , Diabetes Mellitus, Experimental/*genetics , Diabetes Mellitus, Type 2/*genetics , RNA, Messenger/*genetics , Ribonuclease III/*genetics, Adult ; Aged ; Aging/metabolism ; Aging/pathology ; Alu Elements/genetics ; Animals ; Bone Marrow/metabolism ; Bone Marrow/pathology ; Circadian Rhythm/genetics ; DEAD-box RNA Helicases/metabolism ; Diabetes Mellitus, Experimental/metabolism ; Diabetes Mellitus, Experimental/pathology ; Diabetes Mellitus, Type 2/metabolism ; Diabetes Mellitus, Type 2/pathology ; Female ; Gene Expression Regulation ; Humans ; Liver/metabolism ; Liver/pathology ; Male ; Mice ; MicroRNAs/genetics ; MicroRNAs/metabolism ; Middle Aged ; RNA, Double-Stranded/genetics ; RNA, Double-Stranded/metabolism ; RNA, Messenger/metabolism ; Retina/metabolism ; Retina/pathology ; Ribonuclease III/metabolism ; Suprachiasmatic Nucleus/metabolism ; Suprachiasmatic Nucleus/pathology

المؤلفون: Hu P; Departments of Ophthalmology, Pathology, and Pharmacology and Cancer Biology, Duke University, Durham, NC 27710., Herrmann R, Bednar A, Saloupis P, Dwyer MA, Yang P, Qi X, Thomas RS, Jaffe GJ, Boulton ME, McDonnell DP, Malek G

المصدر: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2013 Oct 22; Vol. 110 (43), pp. E4069-78. Date of Electronic Publication: 2013 Oct 08.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

مواضيع طبية MeSH: Disease Models, Animal*, Aging/*metabolism , Macular Degeneration/*metabolism , Pigment Epithelium of Eye/*metabolism , Receptors, Aryl Hydrocarbon/*deficiency, Adolescent ; Adult ; Aging/genetics ; Aging/pathology ; Animals ; Bruch Membrane/metabolism ; Bruch Membrane/pathology ; Bruch Membrane/ultrastructure ; Cell Line ; Child ; Extracellular Matrix/metabolism ; Female ; Humans ; Lipofuscin/metabolism ; Lipoproteins, LDL/blood ; Lipoproteins, LDL/metabolism ; Macular Degeneration/genetics ; Macular Degeneration/pathology ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Microscopy, Electron ; Middle Aged ; Pigment Epithelium of Eye/pathology ; Pigment Epithelium of Eye/ultrastructure ; RNA Interference ; Receptors, Aryl Hydrocarbon/genetics ; Tight Junctions/metabolism ; Tight Junctions/pathology ; Young Adult

المؤلفون: Lin H; Department of Ophthalmology and Visual Sciences, University of Texas Medical Branch, Galveston, Texas 77555-1106, USA., Xu H, Liang FQ, Liang H, Gupta P, Havey AN, Boulton ME, Godley BF

المصدر: Investigative ophthalmology & visual science [Invest Ophthalmol Vis Sci] 2011 Jun 01; Vol. 52 (6), pp. 3521-9. Date of Electronic Publication: 2011 Jun 01.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Association For Research In Vision And Ophthalmology (Arvo) Country of Publication: United States NLM ID: 7703701 Publication Model: Electronic Cited Medium: Internet ISSN: 1552-5783 (Electronic) Linking ISSN: 01460404 NLM ISO Abbreviation: Invest Ophthalmol Vis Sci Subsets: MEDLINE

مواضيع طبية MeSH: DNA Damage*, Aging/*physiology , DNA Repair/*physiology , DNA, Mitochondrial/*metabolism , Macular Degeneration/*metabolism , Retinal Pigment Epithelium/*metabolism, Adult ; Aged ; Aged, 80 and over ; Blotting, Western ; Cells, Cultured ; DNA Glycosylases/metabolism ; DNA Mutational Analysis ; DNA, Mitochondrial/genetics ; Humans ; Hydrogen Peroxide/toxicity ; Macular Degeneration/genetics ; Mutation ; Polymerase Chain Reaction ; Retinal Pigment Epithelium/drug effects ; Tissue Donors ; Young Adult

المؤلفون: Beattie JR; Centre for Vision and Vascular Science, School of Medicine and Dentistry, Queen's University Belfast, Belfast, UK., Pawlak AM, Boulton ME, Zhang J, Monnier VM, McGarvey JJ, Stitt AW

المصدر: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2010 Dec; Vol. 24 (12), pp. 4816-24. Date of Electronic Publication: 2010 Aug 04.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Federation of American Societies for Experimental Biology Country of Publication: United States NLM ID: 8804484 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1530-6860 (Electronic) Linking ISSN: 08926638 NLM ISO Abbreviation: FASEB J Subsets: MEDLINE

مواضيع طبية MeSH: Spectrum Analysis, Raman*, Aging/*physiology , Bruch Membrane/*metabolism , Eye Proteins/*metabolism , Lipid Metabolism/*physiology, Adult ; Aged ; Aged, 80 and over ; Glycation End Products, Advanced/metabolism ; Humans ; In Vitro Techniques ; Middle Aged

المؤلفون: Jarrett SG; Department of Molecular and Biomedical Pharmacology, College of Medicine, University of Kentucky, Lexington, KY, USA., Lewin AS, Boulton ME

المصدر: Ophthalmic research [Ophthalmic Res] 2010; Vol. 44 (3), pp. 179-90. Date of Electronic Publication: 2010 Sep 09.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Review

بيانات الدورية: Publisher: Karger Country of Publication: Switzerland NLM ID: 0267442 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1423-0259 (Electronic) Linking ISSN: 00303747 NLM ISO Abbreviation: Ophthalmic Res Subsets: MEDLINE

مواضيع طبية MeSH: Mutation*, Aging/*physiology , DNA, Mitochondrial/*genetics , Eye Diseases, Hereditary/*genetics , Mitochondria/*physiology, Animals ; Humans ; Reactive Oxygen Species

المؤلفون: Boulton ME

المصدر: Journal of cataract and refractive surgery [J Cataract Refract Surg] 2009 Aug; Vol. 35 (8), pp. 1479; author reply 1479-80.

نوع المنشور: Comment; Letter

بيانات الدورية: Publisher: Wolters Kluwer on behalf of ASCRS and ESCRS Country of Publication: United States NLM ID: 8604171 Publication Model: Print Cited Medium: Internet ISSN: 1873-4502 (Electronic) Linking ISSN: 08863350 NLM ISO Abbreviation: J Cataract Refract Surg Subsets: MEDLINE

مواضيع طبية MeSH: Lenses, Intraocular*, Aging/*physiology , Lipofuscin/*metabolism , Radiation Injuries/*prevention & control , Retina/*radiation effects , Retinal Degeneration/*prevention & control, Aphakia, Postcataract/metabolism ; Humans ; Light/adverse effects ; Pseudophakia/metabolism ; Radiation Injuries/etiology ; Radiation Injuries/metabolism ; Retinal Degeneration/etiology ; Retinal Degeneration/metabolism ; Sunlight/adverse effects

المؤلفون: Glenn JV; Centre for Vision and Vascular Science, School of Medicine, Dentistry and BioMedical Science, Queen's University, Northern Ireland, United Kingdom., Mahaffy H, Wu K, Smith G, Nagai R, Simpson DA, Boulton ME, Stitt AW

المصدر: Investigative ophthalmology & visual science [Invest Ophthalmol Vis Sci] 2009 Jan; Vol. 50 (1), pp. 441-51. Date of Electronic Publication: 2008 Aug 01.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Association For Research In Vision And Ophthalmology (Arvo) Country of Publication: United States NLM ID: 7703701 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-5783 (Electronic) Linking ISSN: 01460404 NLM ISO Abbreviation: Invest Ophthalmol Vis Sci Subsets: MEDLINE

مواضيع طبية MeSH: Aging/*physiology , Bruch Membrane/*metabolism , Cathepsin D/*metabolism , Glycation End Products, Advanced/*metabolism , Lipofuscin/*metabolism , Retinal Diseases/*metabolism , Retinal Pigment Epithelium/*metabolism, Adult ; Aged ; Aged, 80 and over ; Bruch Membrane/ultrastructure ; Cathepsin D/genetics ; Cell Line ; Choroid/metabolism ; Choroid/ultrastructure ; Female ; Fluorescence ; Glycation End Products, Advanced/genetics ; Humans ; Lipofuscin/genetics ; Male ; Microscopy, Confocal ; Middle Aged ; Oligonucleotide Array Sequence Analysis ; RNA, Messenger/metabolism ; Retinal Diseases/pathology ; Retinal Pigment Epithelium/ultrastructure ; Reverse Transcriptase Polymerase Chain Reaction ; Up-Regulation

المؤلفون: Glenn JV; Centre for Vision Science, School of Biomedical Science, Faculty of Medicine and Health Sciences, Queen's University Belfast, Belfast BT12 6BA, Northern Ireland., Beattie JR, Barrett L, Frizzell N, Thorpe SR, Boulton ME, McGarvey JJ, Stitt AW

المصدر: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2007 Nov; Vol. 21 (13), pp. 3542-52. Date of Electronic Publication: 2007 Jun 12.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Federation of American Societies for Experimental Biology Country of Publication: United States NLM ID: 8804484 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1530-6860 (Electronic) Linking ISSN: 08926638 NLM ISO Abbreviation: FASEB J Subsets: MEDLINE

مواضيع طبية MeSH: Aging/*physiology , Bruch Membrane/*metabolism , Eye/*metabolism , Glycation End Products, Advanced/*metabolism , Microscopy, Confocal/*methods , Spectrum Analysis, Raman/*methods, Adult ; Aged ; Aged, 80 and over ; Chromatography, High Pressure Liquid ; Female ; Gas Chromatography-Mass Spectrometry ; Humans ; Male ; Middle Aged

المؤلفون: Albon J; Cell and Molecular Biology Unit, School of Optometry and Vision Sciences, Cardiff Institute of Tissue Engineering and Repair, Cardiff University, Cardiff, Wales, United Kingdom. albonj@cardiff.ac.uk, Farrant S, Akhtar S, Young R, Boulton ME, Smith G, Taylor M, Guggenheim J, Morgan JE

المصدر: Investigative ophthalmology & visual science [Invest Ophthalmol Vis Sci] 2007 May; Vol. 48 (5), pp. 2134-44.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Association For Research In Vision And Ophthalmology (Arvo) Country of Publication: United States NLM ID: 7703701 Publication Model: Print Cited Medium: Print ISSN: 0146-0404 (Print) Linking ISSN: 01460404 NLM ISO Abbreviation: Invest Ophthalmol Vis Sci Subsets: MEDLINE

مواضيع طبية MeSH: Aging/*physiology , Connective Tissue/*anatomy & histology , Connective Tissue Cells/*cytology , Optic Nerve/*ultrastructure, Animals ; Collagen/metabolism ; Connective Tissue/metabolism ; Connective Tissue Cells/metabolism ; Elastin/metabolism ; Fibronectins/metabolism ; Fluorescent Antibody Technique, Indirect ; Glial Fibrillary Acidic Protein/metabolism ; Microscopy, Electron, Scanning ; Microscopy, Electron, Transmission ; Optic Disk/metabolism ; Optic Disk/ultrastructure ; Optic Nerve/metabolism ; Retinal Vessels/cytology ; Tupaiidae

المؤلفون: Rózanowska M; Department of Biophysics, Faculty of Biotechnology, Kraków, Poland. School of Optometry and Vision Sciences, Cardiff University, Cardiff, United Kingdom. rozanowskamb@cf.ac.uk, Pawlak A, Rózanowski B, Skumatz C, Zareba M, Boulton ME, Burke JM, Sarna T, Simon JD

المصدر: Investigative ophthalmology & visual science [Invest Ophthalmol Vis Sci] 2004 Apr; Vol. 45 (4), pp. 1052-60.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

بيانات الدورية: Publisher: Association For Research In Vision And Ophthalmology (Arvo) Country of Publication: United States NLM ID: 7703701 Publication Model: Print Cited Medium: Print ISSN: 0146-0404 (Print) Linking ISSN: 01460404 NLM ISO Abbreviation: Invest Ophthalmol Vis Sci Subsets: MEDLINE

مواضيع طبية MeSH: Aging/*physiology , Lipofuscin/*radiation effects , Pigment Epithelium of Eye/*radiation effects, Adolescent ; Adult ; Aged ; Aged, 80 and over ; Child ; Child, Preschool ; Chloroform/chemistry ; Electron Spin Resonance Spectroscopy ; Humans ; Infant ; Lipofuscin/metabolism ; Middle Aged ; Oxidative Stress ; Oxygen/metabolism ; Pigment Epithelium of Eye/metabolism ; Reactive Oxygen Species/metabolism ; Solubility ; Spin Trapping ; Superoxides/metabolism ; Tissue Donors ; Vision, Ocular