المؤلفون: Wen C; Interdepartmental Program in Bioinformatics, University of California, Los Angeles, Los Angeles, CA 90095, USA.; Department of Psychiatry, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.; Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA., Margolis M; Department of Psychiatry, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.; Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA., Dai R; Department of Psychiatry, SUNY Upstate Medical University, Syracuse, NY 13210, USA., Zhang P; Department of Psychiatry, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.; Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA., Przytycki PF; Gladstone Institute of Data Science and Biotechnology, San Francisco, CA 94158, USA., Vo DD; Department of Psychiatry, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.; Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.; Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.; Lifespan Brain Institute, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA., Bhattacharya A; Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.; Institute for Quantitative and Computational Biosciences, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA., Matoba N; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.; UNC Neuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Tang M; Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.; Lifespan Brain Institute, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA., Jiao C; Department of Psychiatry, SUNY Upstate Medical University, Syracuse, NY 13210, USA.; Université Paris Cité, Institute of Psychiatry and Neuroscience of Paris (IPNP), INSERM U1266, Team Krebs, 75014 Paris, France., Kim M; Department of Psychiatry, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.; Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA., Tsai E; Department of Psychiatry, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.; Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA., Hoh C; Department of Psychiatry, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.; Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA., Aygün N; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.; UNC Neuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Walker RL; Interdepartmental Program in Bioinformatics, University of California, Los Angeles, Los Angeles, CA 90095, USA.; Department of Psychiatry, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.; Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA., Chatzinakos C; Department of Psychiatry, Harvard Medical School, Boston, MA 02215, USA.; McLean Hospital, Belmont, MA 02478, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Clarke D; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520, USA., Pratt H; Program in Bioinformatics and Integrative Biology, University of Massachusetts Medical School, Worcester, MA 01605, USA., Peters MA; CNS Data Coordination Group, Sage Bionetworks, Seattle, WA 98109, USA., Gerstein M; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520, USA.; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06520, USA.; Department of Computer Science, Yale University, New Haven, CT 06520, USA.; Department of Statistics and Data Science, Yale University, New Haven, CT 06520, USA., Daskalakis NP; Department of Psychiatry, Harvard Medical School, Boston, MA 02215, USA.; McLean Hospital, Belmont, MA 02478, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Weng Z; Program in Bioinformatics and Integrative Biology, University of Massachusetts Medical School, Worcester, MA 01605, USA., Jaffe AE; Lieber Institute for Brain Development, Baltimore, MD 21205, USA.; Department of Psychiatry & Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.; Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.; Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.; Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.; Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.; Neumora Therapeutics, Watertown, MA 02472, USA., Kleinman JE; Lieber Institute for Brain Development, Baltimore, MD 21205, USA.; Department of Psychiatry & Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., Hyde TM; Lieber Institute for Brain Development, Baltimore, MD 21205, USA.; Department of Psychiatry & Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., Weinberger DR; Lieber Institute for Brain Development, Baltimore, MD 21205, USA.; Department of Psychiatry & Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.; Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.; Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., Bray NJ; MRC Centre for Neuropsychiatric Genetics & Genomics, Division of Psychological Medicine & Clinical Neurosciences, Cardiff University School of Medicine, Cardiff CF24 4HQ, UK., Sestan N; Department of Comparative Medicine, Yale University School of Medicine, New Haven, CT 06520, USA.; Department of Neuroscience, Yale University School of Medicine, New Haven, CT 06520, USA., Geschwind DH; Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.; Program in Neurogenetics, Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.; Institute for Precision Health, University of California, Los Angeles, Los Angeles, CA 90095, USA., Roeder K; Department of Statistics & Data Science, Carnegie Mellon University, Pittsburgh, PA 15213, USA.; Computational Biology Department, Carnegie Mellon University, Pittsburgh, PA 15213, USA., Gusev A; Department of Medical Oncology, Division of Population Sciences, Dana-Farber Cancer Institute, Boston, MA 02215, USA.; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; Harvard Medical School, Boston, MA 02215, USA.; Division of Genetics, Brigham and Women's Hospital, Boston, MA 02215, USA., Pasaniuc B; Interdepartmental Program in Bioinformatics, University of California, Los Angeles, Los Angeles, CA 90095, USA.; Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.; Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.; Institute for Precision Health, University of California, Los Angeles, Los Angeles, CA 90095, USA.; Department of Computational Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA., Stein JL; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.; UNC Neuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Love MI; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.; Department of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Pollard KS; Gladstone Institute of Data Science and Biotechnology, San Francisco, CA 94158, USA.; Department of Epidemiology & Biostatistics, University of California, San Francisco, San Francisco, CA 94158, USA.; Chan Zuckerberg Biohub, San Francisco, CA 94158, USA., Liu C; Department of Psychiatry, SUNY Upstate Medical University, Syracuse, NY 13210, USA.; Center for Medical Genetics & Hunan Key Laboratory of Medical Genetics, School of Life Sciences, Central South University, Changsha, Hunan 410008, China., Gandal MJ; Interdepartmental Program in Bioinformatics, University of California, Los Angeles, Los Angeles, CA 90095, USA.; Department of Psychiatry, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.; Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.; Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.; Lifespan Brain Institute, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.

مؤلفون مشاركون: PsychENCODE Consortium†, PsychENCODE Consortium

المصدر: Science (New York, N.Y.) [Science] 2024 May 24; Vol. 384 (6698), pp. eadh0829. Date of Electronic Publication: 2024 May 24.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE

مواضيع طبية MeSH: Alternative Splicing* , Brain*/metabolism , Brain*/growth & development , Brain*/embryology , Gene Expression Regulation, Developmental* , Mental Disorders*/genetics, Humans ; Atlases as Topic ; Autism Spectrum Disorder/genetics ; Gene Regulatory Networks ; Genome-Wide Association Study ; Protein Isoforms/genetics ; Protein Isoforms/metabolism ; Quantitative Trait Loci ; Schizophrenia/genetics ; Transcriptome