المؤلفون: Liu B; Jiangsu Key Laboratory of Drug Design & Optimization, Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 211100, Jiangsu, China., Li X; Jiangsu Key Laboratory of Drug Design & Optimization, Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 211100, Jiangsu, China., Liu Z; Jiangsu Key Laboratory of Drug Design & Optimization, Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 211100, Jiangsu, China., He B; Jiangsu Key Laboratory of Drug Design & Optimization, Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 211100, Jiangsu, China., Xu H; Nanjing Foreign Language School, Nanjing 210008, Jiangsu, China., Cao J; Jiangsu Key Laboratory of Drug Design & Optimization, Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 211100, Jiangsu, China., Zeng F; Jiangsu Key Laboratory of Drug Design & Optimization, Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 211100, Jiangsu, China., Feng H; Jiangsu Key Laboratory of Drug Design & Optimization, Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 211100, Jiangsu, China., Ren Y; Jiangsu Key Laboratory of Drug Design & Optimization, Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 211100, Jiangsu, China., Li H; Jiangsu Key Laboratory of Drug Design & Optimization, Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 211100, Jiangsu, China., Wang T; Jiangsu Key Laboratory of Drug Design & Optimization, Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 211100, Jiangsu, China., Li J; Pathology and PDX Efficacy Center, China Pharmaceutical University, Nanjing 211100, Jiangsu, China., Ye Y; Pathology and PDX Efficacy Center, China Pharmaceutical University, Nanjing 211100, Jiangsu, China., Zhao L; School of Basic Medicine and Clinical Pharmacology, China Pharmaceutical University, Nanjing 211100, Jiangsu, China., Ran C; Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02129, United States., Li Y; Jiangsu Key Laboratory of Drug Design & Optimization, Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 211100, Jiangsu, China.

المصدر: Journal of medicinal chemistry [J Med Chem] 2024 Jun 13; Vol. 67 (11), pp. 9104-9123. Date of Electronic Publication: 2024 Jun 03.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Alzheimer Disease*/diagnosis , Alzheimer Disease*/diagnostic imaging , Fluorescent Dyes*/chemistry , Fluorescent Dyes*/chemical synthesis , Amyloid beta-Peptides*/metabolism , Drug Design* , Early Diagnosis*, Animals ; Mice ; Humans ; Brain/diagnostic imaging ; Brain/metabolism ; Mice, Transgenic

المؤلفون: Lin P; Second Department of Neurology, The Second Affiliated Hospital of Qiqihar Medical University, Qiqihar, China., Wang J; Second Department of Neurology, The Second Affiliated Hospital of Qiqihar Medical University, Qiqihar, China., Li Y; Second Department of Neurology, The Second Affiliated Hospital of Qiqihar Medical University, Qiqihar, China., Li G; Department of Anatomy, Basic Medical College, Qiqihar Medical University, Qiqihar, China., Wang Y; Fifth Department of Neurology, The Second Affiliated Hospital of Qiqihar Medical University, Qiqihar, China.

المصدر: Dementia and geriatric cognitive disorders [Dement Geriatr Cogn Disord] 2024; Vol. 53 (3), pp. 107-118. Date of Electronic Publication: 2024 Apr 04.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Karger Country of Publication: Switzerland NLM ID: 9705200 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1421-9824 (Electronic) Linking ISSN: 14208008 NLM ISO Abbreviation: Dement Geriatr Cogn Disord Subsets: MEDLINE

مواضيع طبية MeSH: Ferroptosis*/physiology , Alzheimer Disease*/genetics , Alzheimer Disease*/metabolism , RNA, Long Noncoding*/genetics , RNA, Long Noncoding*/metabolism , Forkhead Box Protein O1*/genetics , Forkhead Box Protein O1*/metabolism , Neurons*/metabolism , Amyloid beta-Peptides*/metabolism , Disease Models, Animal* , tau Proteins*/metabolism , tau Proteins*/genetics, Animals ; Mice ; Humans ; Hippocampus/metabolism ; Male ; Phospholipid Hydroperoxide Glutathione Peroxidase/genetics ; Reactive Oxygen Species/metabolism ; Lipid Peroxidation/physiology ; Mice, Inbred C57BL

المؤلفون: Zeng F; State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210009, China; Jiangsu Key Laboratory of Drug Design and Optimization, Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 21198, China., Yang J; State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210009, China; Jiangsu Key Laboratory of Drug Design and Optimization, Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 21198, China., Li X; State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210009, China; Jiangsu Key Laboratory of Drug Design and Optimization, Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 21198, China., Peng K; Jiangsu Key Laboratory of Drug Design and Optimization, Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 21198, China., Ran C; Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02129, USA., Xu Y; State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210009, China; Jiangsu Key Laboratory of Drug Design and Optimization, Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 21198, China. Electronic address: xu_yungen@hotmail.com., Li Y; State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210009, China; Jiangsu Key Laboratory of Drug Design and Optimization, Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 21198, China. Electronic address: yuyanli@cpu.edu.cn.

المصدر: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2020 Jul 01; Vol. 28 (13), pp. 115559. Date of Electronic Publication: 2020 May 12.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Science Country of Publication: England NLM ID: 9413298 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3391 (Electronic) Linking ISSN: 09680896 NLM ISO Abbreviation: Bioorg Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Alzheimer Disease/*diagnostic imaging , Amyloid beta-Peptides/*analysis , Borinic Acids/*chemical synthesis , Fluorescent Dyes/*chemical synthesis , Fluorescent Dyes/*metabolism, Animals ; Blood-Brain Barrier/metabolism ; Borinic Acids/metabolism ; Brain/metabolism ; Cell Survival ; Disease Models, Animal ; Female ; Humans ; In Vitro Techniques ; Infrared Rays ; Mice ; Mice, Inbred C57BL ; Molecular Structure ; Optical Imaging

المؤلفون: Yang J; State Key Laboratory of Natural Medicines , China Pharmaceutical University , Nanjing 210009 , China., Zeng F; State Key Laboratory of Natural Medicines , China Pharmaceutical University , Nanjing 210009 , China., Ge Y; State Key Laboratory of Natural Medicines , China Pharmaceutical University , Nanjing 210009 , China., Peng K; State Key Laboratory of Natural Medicines , China Pharmaceutical University , Nanjing 210009 , China., Li X; State Key Laboratory of Natural Medicines , China Pharmaceutical University , Nanjing 210009 , China., Li Y; Jiangsu Key Laboratory of Drug Design and Optimization, Department of Medicinal Chemistry , China Pharmaceutical University , Nanjing 21009 , China., Xu Y; State Key Laboratory of Natural Medicines , China Pharmaceutical University , Nanjing 210009 , China.; Jiangsu Key Laboratory of Drug Design and Optimization, Department of Medicinal Chemistry , China Pharmaceutical University , Nanjing 21009 , China.

المصدر: Bioconjugate chemistry [Bioconjug Chem] 2020 Jan 15; Vol. 31 (1), pp. 2-15. Date of Electronic Publication: 2019 Dec 16.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Review

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9010319 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4812 (Electronic) Linking ISSN: 10431802 NLM ISO Abbreviation: Bioconjug Chem Subsets: MEDLINE

مواضيع طبية MeSH: Alzheimer Disease/*diagnosis , Amyloid beta-Peptides/*analysis , Fluorescent Dyes/*chemistry , Reactive Oxygen Species/*analysis , tau Proteins/*analysis, Alzheimer Disease/diagnostic imaging ; Animals ; Humans ; Microscopy, Fluorescence/methods ; Optical Imaging/methods ; Spectrometry, Fluorescence/methods

المؤلفون: Yang J; State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, 210009, China. yuyanli@cpu.edu.cn and Jiangsu Key Laboratory of Drug Design and Optimization, Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing, 210098, China., Zeng F; Jiangsu Key Laboratory of Drug Design and Optimization, Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing, 210098, China., Li X; Jiangsu Key Laboratory of Drug Design and Optimization, Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing, 210098, China., Ran C; Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02129, USA., Xu Y; State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, 210009, China. yuyanli@cpu.edu.cn and Jiangsu Key Laboratory of Drug Design and Optimization, Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing, 210098, China., Li Y; State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, 210009, China. yuyanli@cpu.edu.cn and Jiangsu Key Laboratory of Drug Design and Optimization, Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing, 210098, China.

المصدر: Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2020 Jan 14; Vol. 56 (4), pp. 583-586. Date of Electronic Publication: 2019 Dec 12.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 9610838 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1364-548X (Electronic) Linking ISSN: 13597345 NLM ISO Abbreviation: Chem Commun (Camb) Subsets: MEDLINE

مواضيع طبية MeSH: Alzheimer Disease/*diagnosis , Amyloid beta-Peptides/*analysis , Fluorescent Dyes/*chemistry, Animals ; Cell Line ; Cell Survival/drug effects ; Fluorescent Dyes/pharmacology ; Infrared Rays ; Mice ; Mice, Inbred C57BL ; Mice, Inbred ICR ; Mice, Transgenic ; Models, Molecular ; Molecular Structure ; Optical Imaging

المؤلفون: Yang J; Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02129, USA.; School of Pharmacy, China Pharmaceutical University, Nanjing, 210009, China., Yang J; Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02129, USA.; School of Pharmaceutical Science, Soochow University, Suzhou, 215006, China., Li Y; School of Pharmacy, China Pharmaceutical University, Nanjing, 210009, China., Xu Y; School of Pharmacy, China Pharmaceutical University, Nanjing, 210009, China., Ran C; Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02129, USA. cran@nmr.mgh.harvard.edu.

المصدر: Molecular imaging and biology [Mol Imaging Biol] 2019 Feb; Vol. 21 (1), pp. 35-43.

نوع المنشور: Evaluation Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Springer Country of Publication: United States NLM ID: 101125610 Publication Model: Print Cited Medium: Internet ISSN: 1860-2002 (Electronic) Linking ISSN: 15361632 NLM ISO Abbreviation: Mol Imaging Biol

مواضيع طبية MeSH: Diagnostic Techniques, Ophthalmological*, Alzheimer Disease/*diagnosis , Optical Imaging/*methods, Alzheimer Disease/drug therapy ; Alzheimer Disease/genetics ; Alzheimer Disease/pathology ; Amyloid beta-Peptides/genetics ; Animals ; Disease Models, Animal ; Disease Progression ; Drug Monitoring/methods ; Eye/chemistry ; Eye/diagnostic imaging ; Eye/pathology ; Female ; Fluorescent Dyes/administration & dosage ; Humans ; Mice ; Mice, Transgenic ; Presenilin-1/genetics ; Pyrimidines/therapeutic use ; Reactive Oxygen Species/analysis ; Spectroscopy, Near-Infrared/methods ; Thiazines/therapeutic use

المؤلفون: Zeng F; Department of Medicinal Chemistry, Jiangsu Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing 211198, China., Li Y; Department of Medicinal Chemistry, Jiangsu Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing 211198, China., Xu Y; Department of Medicinal Chemistry, Jiangsu Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing 211198, China., Yang J; Department of Medicinal Chemistry, Jiangsu Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing 211198, China., Liu Z; Department of Medicinal Chemistry, Jiangsu Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing 211198, China., Li X; Department of Medicinal Chemistry, Jiangsu Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing 211198, China., Ren L; Department of Medicinal Chemistry, Jiangsu Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing 211198, China.

المصدر: Current Alzheimer research [Curr Alzheimer Res] 2019; Vol. 16 (12), pp. 1132-1142.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Review

بيانات الدورية: Publisher: Bentham Science Publishers Country of Publication: United Arab Emirates NLM ID: 101208441 Publication Model: Print Cited Medium: Internet ISSN: 1875-5828 (Electronic) Linking ISSN: 15672050 NLM ISO Abbreviation: Curr Alzheimer Res Subsets: MEDLINE

مواضيع طبية MeSH: Alzheimer Disease/*diagnostic imaging , Alzheimer Disease/*metabolism , Amyloid beta-Peptides/*metabolism , Drug Delivery Systems/*methods , Fluorescent Dyes/*metabolism, Drug Delivery Systems/trends ; Early Diagnosis ; Humans ; Plaque, Amyloid/diagnostic imaging ; Plaque, Amyloid/metabolism

المؤلفون: Liu H; Jiangsu Key Laboratory of Drug Design & Optimization, Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, China., Yang J; Jiangsu Key Laboratory of Drug Design & Optimization, Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, China.; Molecular Imaging Laboratory, Massachusetts General Hospital/Massachusetts Institute of Technology/Harvard Medical School Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital/Harvard Medical School, Charlestown, MA 02129, USA., Wang L; Jiangsu Key Laboratory of Drug Design & Optimization, Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, China., Xu Y; Jiangsu Key Laboratory of Drug Design & Optimization, Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, China., Zhang S; Jiangsu Key Laboratory of Drug Design & Optimization, Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, China., Lv J; Jiangsu Key Laboratory of Drug Design & Optimization, Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, China., Ran C; Molecular Imaging Laboratory, Massachusetts General Hospital/Massachusetts Institute of Technology/Harvard Medical School Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital/Harvard Medical School, Charlestown, MA 02129, USA., Li Y; Jiangsu Key Laboratory of Drug Design & Optimization, Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, China.

المصدر: Future medicinal chemistry [Future Med Chem] 2017 Feb; Vol. 9 (2), pp. 179-198. Date of Electronic Publication: 2017 Jan 27.

نوع المنشور: Journal Article; Review; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Future Science Country of Publication: England NLM ID: 101511162 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1756-8927 (Electronic) Linking ISSN: 17568919 NLM ISO Abbreviation: Future Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Alzheimer Disease/*diagnosis , Alzheimer Disease/*metabolism , Amyloid beta-Peptides/*analysis , Fluorescent Dyes/*analysis , Fluorescent Dyes/*chemistry, Amyloid beta-Peptides/metabolism ; Binding Sites ; Fluorescent Dyes/chemical synthesis ; Humans