المؤلفون: Teng E; Early Clinical Development, Genentech Inc, South San Francisco, California., Manser PT; Biostatistics, Genentech Inc, South San Francisco, California., Pickthorn K; Early Clinical Development, Genentech Inc, South San Francisco, California., Brunstein F; Product Development Safety, Genentech Inc, South San Francisco, California., Blendstrup M; Clinical Operations, Genentech Inc, South San Francisco, California., Sanabria Bohorquez S; Clinical Imaging Group, Genentech Inc, South San Francisco, California., Wildsmith KR; Biomarker Development, Genentech Inc, South San Francisco, California.; Now with Eisai Inc, Woodcliff Lake, New Jersey., Toth B; Biostatistics, Genentech Inc, South San Francisco, California., Dolton M; Roche Products Pty Limited, Sydney, Australia., Ramakrishnan V; Clinical Pharmacology, Genentech Inc, South San Francisco, California., Bobbala A; Product Development Safety, Genentech Inc, South San Francisco, California., Sikkes SAM; Alzheimer Center Amsterdam, Amsterdam Neuroscience, Amsterdam University Medical Center, VU University Amsterdam, Amsterdam, the Netherlands.; Department of Clinical, Neuro- and Developmental Psychology, VU University, Amsterdam, the Netherlands., Ward M; Early Clinical Development, Genentech Inc, South San Francisco, California.; Now with Alector Inc, South San Francisco, California., Fuji RN; Safety Assessment, Genentech Inc, South San Francisco, California., Kerchner GA; F. Hoffmann-La Roche AG, Basel, Switzerland.

مؤلفون مشاركون: Tauriel Investigators

المصدر: JAMA neurology [JAMA Neurol] 2022 Aug 01; Vol. 79 (8), pp. 758-767.

نوع المنشور: Clinical Trial, Phase II; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Medical Association Country of Publication: United States NLM ID: 101589536 Publication Model: Print Cited Medium: Internet ISSN: 2168-6157 (Electronic) Linking ISSN: 21686149 NLM ISO Abbreviation: JAMA Neurol Subsets: MEDLINE

مواضيع طبية MeSH: Alzheimer Disease*/cerebrospinal fluid , Alzheimer Disease*/drug therapy, Aged ; Amyloid beta-Peptides ; Antibodies, Monoclonal/therapeutic use ; Double-Blind Method ; Female ; Humans ; Male ; Treatment Outcome

المؤلفون: Teng E; Early Clinical Development, Genentech, Inc., South San Francisco, CA, USA. teng.edmond@gene.com., Manser PT; Clinical Biostatistics, Genentech, Inc., South San Francisco, CA, USA., Sanabria Bohorquez S; Clinical Imaging Group, Genentech, Inc., South San Francisco, CA, USA., Wildsmith KR; Biomarker Development, Genentech, Inc., South San Francisco, CA, USA., Pickthorn K; Early Clinical Development, Genentech, Inc., South San Francisco, CA, USA., Baker SL; Clinical Imaging Group, Genentech, Inc., South San Francisco, CA, USA.; Molecular Biophysics and Integrated Bioimaging, Lawrence Berkeley National Laboratory, Berkeley, CA, USA., Ward M; Early Clinical Development, Genentech, Inc., South San Francisco, CA, USA.; Current Address: Alector, Inc., South San Francisco, CA, USA., Kerchner GA; Early Clinical Development, Genentech, Inc., South San Francisco, CA, USA.; Current Address: F. Hoffmann-La Roche AG, Basel, Switzerland., Weimer RM; Biomedical Imaging, Genentech, Inc., South San Francisco, CA, USA.

المصدر: Alzheimer's research & therapy [Alzheimers Res Ther] 2021 Dec 01; Vol. 13 (1), pp. 196. Date of Electronic Publication: 2021 Dec 01.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 101511643 Publication Model: Electronic Cited Medium: Internet ISSN: 1758-9193 (Electronic) NLM ISO Abbreviation: Alzheimers Res Ther Subsets: MEDLINE

مواضيع طبية MeSH: Alzheimer Disease*/diagnostic imaging , Alzheimer Disease*/psychology , Cognitive Dysfunction*/diagnostic imaging , Cognitive Dysfunction*/psychology, Amyloid beta-Peptides ; Humans ; Positron-Emission Tomography/methods ; tau Proteins

المؤلفون: Teng, Edmond, Manser, Paul T, Sanabria Bohorquez, Sandra, Wildsmith, Kristin R, Pickthorn, Karen, Baker, Suzanne L, Ward, Michael, Kerchner, Geoffrey A, Weimer, Robby M

المصدر: Alzheimer's Research & Therapy. 13(1)

مصطلحات موضوعية: Health Services and Systems, Health Sciences, Clinical Trials and Supportive Activities, Aging, Acquired Cognitive Impairment, Brain Disorders, Alzheimer's Disease, Dementia, Neurosciences, Neurodegenerative, Clinical Research, Biomedical Imaging, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Detection, screening and diagnosis, 4.1 Discovery and preclinical testing of markers and technologies, Neurological, Alzheimer Disease, Amyloid beta-Peptides, Cognitive Dysfunction, Humans, Positron-Emission Tomography, tau Proteins, Alzheimer’s disease, Cognition, PET, Prognosis, Tau, Medical and Health Sciences, Biomedical and clinical sciences, Health sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/5k2704b5