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1
المؤلفون: Peng Lv, Shi-Liang Huang, Zhen-Quan Liu, Ning Wang, Zhi-Shu Huang, Chun-Li Xia
المصدر: Bioorganic & Medicinal Chemistry. 26:4693-4705
مصطلحات موضوعية: 0301 basic medicine, Swine, Amyloid beta, Clinical Biochemistry, Tau protein, Pharmaceutical Science, tau Proteins, Protein aggregation, Blood–brain barrier, 01 natural sciences, Biochemistry, Protein Aggregates, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, Microscopy, Electron, Transmission, Drug Discovery, medicine, Animals, Humans, Structure–activity relationship, Molecular Biology, Amyloid beta-Peptides, Microscopy, Confocal, biology, 010405 organic chemistry, Chemistry, Organic Chemistry, Surface Plasmon Resonance, Peptide Fragments, In vitro, 0104 chemical sciences, Acridone, HEK293 Cells, 030104 developmental biology, medicine.anatomical_structure, Blood-Brain Barrier, Drug Design, Tacrine, biology.protein, Molecular Medicine, Acridones, Central Nervous System Agents, medicine.drug
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2
المؤلفون: Jun Xu, Jinggong Liu, Lian-Quan Gu, Ling Wang, Qiong Gu, Lijuan Su, Mingxue Wang, Jinbo Gao, Jun Qiu, Shi-Liang Huang, Ding Li, Zhi-Shu Huang
المصدر: Biochimica et Biophysica Acta (BBA) - General Subjects. 1840:2886-2903
مصطلحات موضوعية: Biophysics, Biochemistry, Antioxidants, chemistry.chemical_compound, Western blot, Alzheimer Disease, Cell Line, Tumor, medicine, Humans, MTT assay, Molecular Biology, IC50, Butyrylcholinesterase, Cholinesterase, Amyloid beta-Peptides, biology, medicine.diagnostic_test, Imidazoles, Phenanthrenes, Acetylcholinesterase, Peptide Fragments, Molecular Docking Simulation, chemistry, biology.protein, Thioflavin, Lead compound
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3
المؤلفون: Tian-Miao Ou, Chun-Li Xia, Shi-Liang Huang, Zhen-Quan Liu, Honggen Wang, Zhi-Shu Huang, Jia-Qiang Wu, Jia-Heng Tan, Ning Wang, Ding Li, Qian-Liang Guo
المصدر: European journal of medicinal chemistry. 130
مصطلحات موضوعية: 0301 basic medicine, Programmed cell death, Antioxidant, medicine.medical_treatment, 01 natural sciences, Antioxidants, Cell Line, 03 medical and health sciences, chemistry.chemical_compound, Intragastric administration, Alzheimer Disease, Drug Discovery, medicine, Humans, Pharmacology, Amyloid beta-Peptides, Cell Death, 010405 organic chemistry, Organic Chemistry, Quinoline, Biological activity, General Medicine, Glutathione, 0104 chemical sciences, 030104 developmental biology, Alzheimer's disease treatment, chemistry, Biochemistry, Design synthesis, Blood-Brain Barrier, Drug Design, Quinolines, Cholinesterase Inhibitors, Reactive Oxygen Species
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4
المؤلفون: Zhi-Shu Huang, Ding Li, Yan-Ping Li, Yan He, Wen Luo, Lian-Quan Gu, Shi-Liang Huang
المصدر: European Journal of Medicinal Chemistry. 46:2609-2616
مصطلحات موضوعية: Models, Molecular, Stereochemistry, Crystallography, X-Ray, Chemical synthesis, Antioxidants, Structure-Activity Relationship, chemistry.chemical_compound, Alzheimer Disease, Drug Discovery, medicine, Humans, Structure–activity relationship, Butyrylcholinesterase, Cholinesterase, Pharmacology, Amyloid beta-Peptides, Dose-Response Relationship, Drug, Molecular Structure, biology, Organic Chemistry, Active site, Stereoisomerism, General Medicine, Acetylcholinesterase, Peptide Fragments, chemistry, Enzyme inhibitor, Tacrine, biology.protein, Cholinesterase Inhibitors, medicine.drug
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5
المؤلفون: Shi-Liang Huang, Fang-Xian Ning, Ding Li, Zhi-Shu Huang, Yong-Cheng Li, Min-Hua Nie, Lian-Quan Gu, Jia-Heng Tan, Yan-Ping Li, Tian-Miao Ou, Meng-Bi Yang
المصدر: European Journal of Medicinal Chemistry. 46:1572-1581
مصطلحات موضوعية: Models, Molecular, Tertiary amine, Cell Survival, Amyloid beta, Stereochemistry, Crystallography, X-Ray, Chemical synthesis, Structure-Activity Relationship, chemistry.chemical_compound, Drug Discovery, Tumor Cells, Cultured, Humans, Structure–activity relationship, Methiodide, Butyrylcholinesterase, Pharmacology, Amyloid beta-Peptides, Molecular Structure, biology, Chemistry, Organic Chemistry, Stereoisomerism, General Medicine, Acetylcholinesterase, Peptide Fragments, Enzyme inhibitor, biology.protein, Cholinesterase Inhibitors
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6
المؤلفون: Jia-Heng Tan, Shi-Liang Huang, Tian-Miao Ou, Ding Li, Zhi-Shu Huang, Peng Zhai, Chun-Li Xia, Lian-Quan Gu
المصدر: Current Alzheimer research. 12(5)
مصطلحات موضوعية: Amyloid, Curcumin, Oxygen radical absorbance capacity, Metal ions in aqueous solution, Antioxidants, chemistry.chemical_compound, Protein Aggregates, Structure-Activity Relationship, Microscopy, Electron, Transmission, Aβ protein, Alzheimer Disease, Cell Line, Tumor, Molecule, Structure–activity relationship, Humans, Chelation, Chromans, Chelating Agents, Amyloid beta-Peptides, Molecular Structure, Chemistry, Spectrum Analysis, Combinatorial chemistry, Peptide Fragments, Oxygen, Neuroprotective Agents, Neurology, Biochemistry, Drug Evaluation, Neurology (clinical), Trolox, Copper
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db99582dccbd41df763a31972dbcc31c
https://pubmed.ncbi.nlm.nih.gov/25938868 -
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المؤلفون: Ding Li, Yi-Ping Chen, Shi-Liang Huang, Jun Xu, Yan-Ping Li, Zhi-Shu Huang, Zi-Ying Zhang, Lian-Quan Gu
المصدر: European journal of medicinal chemistry. 66
مصطلحات موضوعية: Circular dichroism, Amyloid beta, Stereochemistry, ADAM10, Antineoplastic Agents, Chemistry Techniques, Synthetic, Resveratrol, Antioxidants, Protein Structure, Secondary, chemistry.chemical_compound, Structure-Activity Relationship, Chalcones, Cell Line, Tumor, Drug Discovery, Amyloid precursor protein, Humans, Lipoxygenase Inhibitors, 5-lipoxygenase-activating protein, Pharmacology, Amyloid beta-Peptides, Arachidonate 5-Lipoxygenase, biology, Chemistry, Organic Chemistry, General Medicine, Peptide Fragments, Molecular Docking Simulation, Arachidonate 5-lipoxygenase, biology.protein, Protein Multimerization, Isoliquiritigenin
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8
المؤلفون: Ding Li, Shuo-Bin Chen, Lian-Quan Gu, Zhi-Shu Huang, Yan He, Pei-Fen Yao, Jia-Heng Tan, Shi-Liang Huang, Zhi-Hong Huang
المصدر: European journal of medicinal chemistry. 63
مصطلحات موضوعية: Models, Molecular, Molecular model, Aché, Cell Survival, Antioxidants, Indole Alkaloids, chemistry.chemical_compound, Inhibitory Concentration 50, Alzheimer Disease, Cell Line, Tumor, Drug Discovery, Humans, Cytotoxicity, Butyrylcholinesterase, Chelating Agents, Pharmacology, Amyloid beta-Peptides, biology, Dose-Response Relationship, Drug, Molecular Structure, Chemistry, Organic Chemistry, Active site, General Medicine, Acetylcholinesterase, language.human_language, Peptide Fragments, Protein Structure, Tertiary, Kinetics, Biochemistry, Models, Chemical, biology.protein, language, Curcumin, Biocatalysis, Quinazolines, Trolox, Cholinesterase Inhibitors, Protein Binding
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9
المؤلفون: Hao-Tao Zhao, Jiang-Ke Qin, Shu-Ming Zhong, Zhen-Feng Chen, Zhi-Shu Huang, Hong Liang, Li-Zhen Zhao, Huang Tang, Shi-Liang Huang
المصدر: European journal of medicinal chemistry. 46(10)
مصطلحات موضوعية: Amyloid, Aporphines, Aché, Stereochemistry, Models, Biological, chemistry.chemical_compound, Alzheimer Disease, Drug Discovery, medicine, Moiety, Animals, Humans, Horses, Binding site, Butyrylcholinesterase, Pharmacology, Amyloid beta-Peptides, Organic Chemistry, General Medicine, Acetylcholinesterase, language.human_language, In vitro, chemistry, Biochemistry, Blood-Brain Barrier, Tacrine, Electrophorus, language, Cholinesterase Inhibitors, Linker, medicine.drug
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10
المؤلفون: Lian-Quan Gu, Ding Li, Wen Luo, Jia-Heng Tan, Yan-Ping Li, Tian-Miao Ou, Yan He, Shi-Liang Huang, Zhi-Shu Huang
المصدر: Bioorganicmedicinal chemistry. 19(2)
مصطلحات موضوعية: Amyloid beta, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Biochemistry, chemistry.chemical_compound, Drug Discovery, medicine, Moiety, Computer Simulation, Binding site, Molecular Biology, Butyrylcholinesterase, Amyloid beta-Peptides, Binding Sites, biology, Organic Chemistry, Active site, Benzene, Acetylcholinesterase, Peptide Fragments, Kinetics, chemistry, Tacrine, Drug Design, biology.protein, Curcumin, Molecular Medicine, Cholinesterase Inhibitors, medicine.drug