المؤلفون: Sylvie Lariven, Jean-Pierre Laissy, Monique Boukobza, S. Houze

المصدر: Revue Neurologique. 177:1176-1182

مصطلحات موضوعية: Adult, Male, Pathology, medicine.medical_specialty, Trypanosoma brucei gambiense, Hepatosplenomegaly, Physical examination, Melarsoprol, Polymerase Chain Reaction, 03 medical and health sciences, 0302 clinical medicine, Cerebrospinal fluid, parasitic diseases, Biopsy, medicine, Animals, Humans, Serologic Tests, African trypanosomiasis, 030212 general & internal medicine, Hypoalbuminemia, medicine.diagnostic_test, business.industry, medicine.disease, Magnetic Resonance Imaging, Trypanosomiasis, African, Neurology, Neurology (clinical), medicine.symptom, Vasculitis, business, 030217 neurology & neurosurgery, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e312fadd405ad79f1a7048f24ba9333
https://doi.org/10.1016/j.neurol.2020.11.002

المؤلفون: Linous Munsimbwe, David D. N'Da, Keisuke Suganuma, Boniface Namangala, Anna Seetsi, Noboru Inoue

المصدر: Molecules
Volume 26
Issue 11
Molecules, Vol 26, Iss 3372, p 3372 (2021)

مصطلحات موضوعية: Trypanosoma brucei rhodesiense, Nitrofurans, Trypanosoma brucei gambiense, human African trypanosomiasis, Administration, Oral, Pharmaceutical Science, Drug resistance, Pharmacology, Article, Cell Line, Analytical Chemistry, Mice, Structure-Activity Relationship, 03 medical and health sciences, QD241-441, 0302 clinical medicine, In vivo, Drug Discovery, medicine, Animals, African trypanosomiasis, Physical and Theoretical Chemistry, Cytotoxicity, IC50, trypanocidal drug, 030304 developmental biology, 0303 health sciences, Molecular Structure, Chemistry, Organic Chemistry, nitrofurantoin analog, medicine.disease, Trypanocidal Agents, In vitro, Disease Models, Animal, Trypanosomiasis, African, Nitrofurantoin, animal trypanosomosis, Chemistry (miscellaneous), 030220 oncology & carcinogenesis, Molecular Medicine, Female, medicine.drug

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20ca37ed006d978267ad2db6b44eb232

المؤلفون: Harry P. de Koning, Fabio Zuccotto, Juan A. Bueren-Calabuig, Juan F. Quintana, Mark C. Field, David Horn

المصدر: PLoS Neglected Tropical Diseases, Vol 14, Iss 7, p e0008458 (2020)
PLoS Neglected Tropical Diseases

مصطلحات موضوعية: Glycerol, 0301 basic medicine, RC955-962, Drug Resistance, Drug resistance, Endoplasmic Reticulum, Biochemistry, 0302 clinical medicine, Ubiquitin, Arctic medicine. Tropical medicine, Amino Acids, Protozoans, 0303 health sciences, Secretory Pathway, biology, Protein Stability, Organic Compounds, Chemistry, Monomers, Eukaryota, ER retention, Trypanocidal Agents, Endocytosis, 3. Good health, Cell biology, Infectious Diseases, medicine.anatomical_structure, Drug development, Cell Processes, Physical Sciences, Cellular Structures and Organelles, Basic Amino Acids, Public aspects of medicine, RA1-1270, Aquaglyceroporins, Research Article, medicine.drug, Trypanosoma, Endosome, Trypanosoma brucei brucei, Immunoblotting, 030231 tropical medicine, Glycerol transport, Molecular Probe Techniques, Trypanosoma brucei, Research and Analysis Methods, 03 medical and health sciences, Lysosome, Trypanosoma Brucei, medicine, Animals, Amino Acid Sequence, Molecular Biology Techniques, Molecular Biology, 030304 developmental biology, 030306 microbiology, Lysine, Organic Chemistry, Organisms, Chemical Compounds, Public Health, Environmental and Occupational Health, Biology and Life Sciences, Proteins, Cell Biology, Polymer Chemistry, biology.organism_classification, Parasitic Protozoans, Trypanosomiasis, African, 030104 developmental biology, biology.protein, Lysosomes, Trypanosoma Brucei Gambiense, Pentamidine

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::231dae86f1a43df961dfee49d9db039c
https://eprints.gla.ac.uk/224645/1/224645.pdf

المؤلفون: David I. Ugwu, Uchechukwu C. Okoro, Narendra Kumar Mishra

المصدر: European Journal of Medicinal Chemistry. 154:110-116

مصطلحات موضوعية: Male, Proline, medicine.drug_class, Trypanosoma brucei gambiense, 030231 tropical medicine, Antiprotozoal Agents, Carboxamide, Melarsoprol, Pharmacology, Carrageenan, 01 natural sciences, Anti-inflammatory, Mice, Structure-Activity Relationship, 03 medical and health sciences, 0302 clinical medicine, Parasitic Sensitivity Tests, Drug Discovery, medicine, Animals, Edema, African trypanosomiasis, IC50, Sulfonamides, Dose-Response Relationship, Drug, Molecular Structure, 010405 organic chemistry, Chemistry, Anti-Inflammatory Agents, Non-Steroidal, Organic Chemistry, Excessive sleep, General Medicine, medicine.disease, Rats, 0104 chemical sciences, Bioavailability, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03c12a1d045e67c53d4e04180193ac2a
https://doi.org/10.1016/j.ejmech.2018.05.017

المؤلفون: Nian Chen, Jianfu Zhang, Jingjing Xu, Ke Jin, Yali Weng

المصدر: International Journal of Infectious Diseases, Vol 79, Iss, Pp 34-36 (2019)

مصطلحات موضوعية: 0301 basic medicine, Microbiology (medical), Male, China, Eflornithine, Trypanosoma brucei gambiense, 030106 microbiology, World health, lcsh:Infectious and parasitic diseases, 03 medical and health sciences, 0302 clinical medicine, Fatal Outcome, Communicable Diseases, Imported, Recurrence, parasitic diseases, medicine, Animals, Humans, African trypanosomiasis, lcsh:RC109-216, 030212 general & internal medicine, Gabon, business.industry, General Medicine, Middle Aged, medicine.disease, Virology, Trypanocidal Agents, Infectious Diseases, Trypanosomiasis, African, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d14669dede6ca6bc9d04de35e3ec7c7
http://www.sciencedirect.com/science/article/pii/S120197121834582X

المؤلفون: Sarah A. Thomas, Lea Ann Dailey, Marcelo A. da Silva, Lisa Sanderson, Shanta J. Persaud, Margarita Valero, Simon L. Croft, Mark R. Christie, Hollie Burrell-Saward, Mehmet Fidanboylu, Chris Lorenz, Bo Liu, Cécile A. Dreiss, Rachel C. Brown, Gayathri N. Sekhar, Vanessa Yardley

المصدر: PLoS Neglected Tropical Diseases
Sanderson, L, Da Silva, M, Sekhar, G, Brown, R, Burrell-Saward, H, Fidanboylu, M, Liu, B, Dailey, L A, Dreiss, C, Lorenz, C, Christie, M, Persaud, S, Yardley, V, Croft, S, Valero, M & Thomas, S 2021, ' Drug reformulation for a neglected disease. The NANOHAT project to develop a safer more effective sleeping sickness drug ', PLoS Neglected Tropical Diseases, vol. 15, no. 4, e0009276 . https://doi.org/10.1371/journal.pntd.0009276
PLoS Neglected Tropical Diseases, Vol 15, Iss 4, p e0009276 (2021)

مصطلحات موضوعية: Central Nervous System, Male, Trypanosoma brucei rhodesiense, 0301 basic medicine, Polymers, Physiology, Trypanosoma brucei gambiense, RC955-962, 02 engineering and technology, Pharmacology, Toxicology, Pathology and Laboratory Medicine, Nervous System, Mice, Endocrinology, Arctic medicine. Tropical medicine, Insulin Secretion, Medicine and Health Sciences, African trypanosomiasis, Materials, media_common, 0303 health sciences, Mice, Inbred BALB C, biology, Neglected Diseases, 021001 nanoscience & nanotechnology, Trypanocidal Agents, 3. Good health, Solutions, Chemistry, Infectious Diseases, Macromolecules, Blood-Brain Barrier, Physical Sciences, Toxicity, Female, Public aspects of medicine, RA1-1270, Anatomy, 0210 nano-technology, Research Article, medicine.drug, Drug, Tsetse Flies, media_common.quotation_subject, Materials Science, Material Properties, Trypanosoma brucei, Aqueous Solutions, NANOHAT, Permeability, 03 medical and health sciences, Pharmacokinetics, In vivo, medicine, Animals, Humans, Pentamidine, 030304 developmental biology, Endocrine Physiology, business.industry, Public Health, Environmental and Occupational Health, Neurotoxicity, Biology and Life Sciences, biology.organism_classification, Polymer Chemistry, medicine.disease, Trypanosomiasis, African, 030104 developmental biology, Mixtures, Saline Solutions, Nanocarriers, business

وصف الملف: application/pdf

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https://doi.org/10.1371/journal.pntd.0009276

المؤلفون: Dominic Sparkes, Peter L Chiodini, Douglas Fink, L Hedley

المصدر: British Journal of Hospital Medicine. 77:C157-C160

مصطلحات موضوعية: Trypanosoma brucei rhodesiense, Eflornithine, Tsetse Flies, Trypanosoma brucei gambiense, Suramin, 030231 tropical medicine, 03 medical and health sciences, 0302 clinical medicine, medicine, Animals, Humans, 030212 general & internal medicine, Nifurtimox, Pentamidine, Trypanocidal agent, business.industry, General Medicine, medicine.disease, Trypanocidal Agents, Virology, Insect Vectors, Trypanosomiasis, African, business, Trypanosomiasis, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc907dab0e2de0fb25373f39ded68e11
https://doi.org/10.12968/hmed.2016.77.10.c157

المؤلفون: Jiri Keirsse, Magdalena Radwanska, F Kauffmann, Stefan Magez, Théo Baltz, C De Trez, Jennifer Cnops, Eric Muraille

المساهمون: Cellular and Molecular Immunology, Department of Bio-engineering Sciences, Structural Biology Brussels

المصدر: Parasite Immunology. 38(10):642-647

مصطلحات موضوعية: 0301 basic medicine, trypanosomiasis, Trypanosoma brucei gambiense, Trypanosoma spp, 030231 tropical medicine, Immunology, Virulence, Inflammation, Spleen, Apoptosis, Biology, 03 medical and health sciences, Interferon-gamma, Mice, 0302 clinical medicine, Immune system, parasitic diseases, medicine, Animals, Interferon gamma, B-Lymphocytes, Mice, Inbred BALB C, B lymphocyte, Tumor Necrosis Factor-alpha, medicine.disease, Virology, 030104 developmental biology, medicine.anatomical_structure, Trypanosomiasis, African, inflammation, Parasitic disease, Chronic Disease, Parasitology, Tumor necrosis factor alpha, Female, medicine.symptom, Trypanosomiasis, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c53610137ecb98cc828f71b2d5ba95eb
https://researchportal.unamur.be/en/publications/263bae6d-eea6-4b2c-9aad-21ba1db9686b

المؤلفون: Alexandra G. Raftery, Saloum Jallow, Jean Rodgers, D. G. M. Sutton

المصدر: PLoS Neglected Tropical Diseases, Vol 13, Iss 3, p e0007175 (2019)
PLoS Neglected Tropical Diseases

مصطلحات موضوعية: 0301 basic medicine, Male, Disease, Abortion, Arsenicals, law.invention, chemistry.chemical_compound, Diminazene, Random Allocation, 0302 clinical medicine, Randomized controlled trial, law, Zoonoses, Medicine and Health Sciences, Prospective Studies, Asses, Protozoans, Mammals, education.field_of_study, Pharmaceutics, Triazines, lcsh:Public aspects of medicine, Eukaryota, Trypanocidal Agents, Phenanthridines, Infectious Diseases, Treatment Outcome, Vertebrates, Female, Gambia, Isometamidium chloride, medicine.drug, Research Article, medicine.medical_specialty, Trypanosoma, lcsh:Arctic medicine. Tropical medicine, lcsh:RC955-962, 030231 tropical medicine, Population, Equines, 03 medical and health sciences, Pharmacotherapy, Drug Therapy, Trypanosomiasis, Internal medicine, medicine, Trypanosoma Brucei, Parasitic Diseases, Animals, Horses, education, Protozoan Infections, business.industry, Public Health, Environmental and Occupational Health, Organisms, Biology and Life Sciences, lcsh:RA1-1270, Equidae, medicine.disease, Parasitic Protozoans, 030104 developmental biology, chemistry, Amniotes, Horse Diseases, business, Trypanosoma Brucei Gambiense

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cb839af7a60dfbc11710ffecbd8f5dc
http://europepmc.org/articles/PMC6447232?pdf=render

المؤلفون: David W. Boykin, Donald A. Patrick, Olivier Braissant, Richard R. Tidwell, Michael Zhuo Wang, Reto Brun, Mohamed A. Ismail, Sihyung Yang, Tanja Wenzler

المصدر: Antimicrobial Agents and Chemotherapy. 58:4452-4463

مصطلحات موضوعية: Trypanosoma brucei rhodesiense, Drug, Pyridines, Trypanosoma brucei gambiense, media_common.quotation_subject, Amidines, Melarsoprol, Pharmacology, Biology, Mice, Structure-Activity Relationship, In vivo, medicine, Animals, Humans, Pharmacology (medical), Pentamidine, media_common, Dose-Response Relationship, Drug, Tropical disease, medicine.disease, Trypanocidal Agents, In vitro, Trypanosomiasis, African, Infectious Diseases, Susceptibility, Immunology, Female, Trypanosomiasis, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e55714d75dd88dda3a379bd6657c2d00
https://doi.org/10.1128/aac.02309-13