المؤلفون: Martina Wallace, Le You, Jivani M. Gengatharan, Alan Saghatelian, Antonio Pinto, Christian M. Metallo, Matthew J. Kolar, Michal K. Handzlik, Esther W. Lim, Thekla Cordes, Mehmet G. Badur, Thangaselvam Muthusamy

المصدر: Nature
Nature, vol 586, iss 7831

مصطلحات موضوعية: 0301 basic medicine, Serine C-Palmitoyltransferase, 1-deoxysphinganine, serine palmitoyltransferase, Serine, Mice, chemistry.chemical_compound, 0302 clinical medicine, Neoplasms, Pyruvic Acid, 2.1 Biological and endogenous factors, Aetiology, PHGDH, Cancer, Alanine, Multidisciplinary, anchorage-independent growth, Chemistry, Mitochondria, Cell biology, 5.1 Pharmaceuticals, 030220 oncology & carcinogenesis, Female, Development of treatments and therapeutic interventions, alanine, Cell Division, myriocin, General Science & Technology, Physiological, Glycine, Stress, Article, mitochondrial pyruvate carrier, Membrane Lipids, 03 medical and health sciences, Biosynthesis, Cell Adhesion, Animals, Humans, ceramide, SPTLC1, Phosphoglycerate Dehydrogenase, Deoxysphingolipid, Nutrition, Sphingolipids, Serine C-palmitoyltransferase, HCT116 Cells, Xenograft Model Antitumor Assays, Sphingolipid, Diet, 030104 developmental biology, Cellular, Spheroids

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9979104d4b257b47af2b3c30ced51a87
https://doi.org/10.1038/s41586-020-2609-x