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المؤلفون: Wanhai Xu, Binyuan Yan, Yuqian Yan, Haojie Huang, Yunqian Pan, Jun Pang, Yundong He, Jun Zhang, Lei Shi, Jacob J. Orme
المصدر: Cancer Research. 81:3593-3606
مصطلحات موضوعية: Male, Cancer Research, Apoptosis, Mice, SCID, SPOP, Protein degradation, Mice, Ubiquitin, Biomarkers, Tumor, Tumor Cells, Cultured, SKP2, Animals, Humans, Peroxisomal Multifunctional Protein-2, Cell Proliferation, Zinc finger, biology, Chemistry, Ubiquitination, Nuclear Proteins, Prostatic Neoplasms, Xenograft Model Antitumor Assays, Ubiquitin ligase, Gene Expression Regulation, Neoplastic, Repressor Proteins, Androgen receptor, Oncology, Receptors, Androgen, Mutation, Proteolysis, Androgens, biology.protein, Cancer research, Ectopic expression
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52b5c3e09b470c13f8fb7f4bf6501e28
https://doi.org/10.1158/0008-5472.can-20-3258 -
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المؤلفون: Haojie Huang, Ting Wei, Martin E. Gleave, Ladan Fazli, Lei Shi, Yuzhuo Wang, R. Jeffrey Karnes, Jacob J. Orme, Yundong He, Haoyue Sheng, Zhenqing Ye, Rafael E. Jimenez, Liguo Wang, Liewei Wang, Dong Lin
المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communicationsمصطلحات موضوعية: Male, 0301 basic medicine, General Physics and Astronomy, Angiotensin-Converting Enzyme Inhibitors, Mice, SCID, urologic and male genital diseases, Biochemistry, Mice, chemistry.chemical_compound, Prostate cancer, 0302 clinical medicine, Cancer, Multidisciplinary, Up-Regulation, DNA-Binding Proteins, Organoids, CpG site, Receptors, Androgen, 030220 oncology & carcinogenesis, Benzamides, Signal Transduction, Hepatocyte Nuclear Factor 3-alpha, medicine.drug_class, Science, Article, General Biochemistry, Genetics and Molecular Biology, Angiotensin Receptor Antagonists, 03 medical and health sciences, Nitriles, Phenylthiohydantoin, medicine, Animals, Humans, Enzalutamide, Binding site, Cell Proliferation, Binding Sites, Pioneer factor, Prostatic Neoplasms, Androgen Antagonists, General Chemistry, Androgen, medicine.disease, Xenograft Model Antitumor Assays, Androgen receptor, 030104 developmental biology, chemistry, Cancer research, FOXA1, Transcription Factors
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المؤلفون: Yong Du, Chun Xie, Xin J. Zhou, Sneha Ravikumar, Li Li, Chandra Mohan, Jacob J. Orme
المصدر: International Journal of Molecular Sciences
Volume 22
Issue 4
International Journal of Molecular Sciences, Vol 22, Iss 2059, p 2059 (2021)مصطلحات موضوعية: 0301 basic medicine, Glomerulonephritis, Membranoproliferative, SMAD, Disease, Kidney, Catalysis, Article, Inorganic Chemistry, lcsh:Chemistry, 03 medical and health sciences, 0302 clinical medicine, Immune system, Transforming Growth Factor beta, medicine, Animals, RNA, Messenger, Smad3 Protein, Physical and Theoretical Chemistry, Molecular Biology, lcsh:QH301-705.5, Spectroscopy, anti-GBM nephritis, 129sv strain, 030203 arthritis & rheumatology, Basement membrane, Crescentic glomerulonephritis, business.industry, Organic Chemistry, General Medicine, medicine.disease, TGF-β/SMAD signaling, Computer Science Applications, Mice, Inbred C57BL, 030104 developmental biology, medicine.anatomical_structure, Gene Expression Regulation, lcsh:Biology (General), lcsh:QD1-999, Cancer research, Phosphorylation, Collagen, business, Nephritis, Signal Transduction, Transforming growth factor
وصف الملف: application/pdf
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المؤلفون: Di Wu, Dejie Wang, Yunqian Pan, Zhenqing Ye, Yu-Tian Xiao, Haojie Huang, Ting Wei, Shancheng Ren, Liguo Wang, Jacob J. Orme, Yuqian Yan
المصدر: Cell Reports. 34:108744
مصطلحات موضوعية: Male, 0301 basic medicine, BRD4, Nerve Tissue Proteins, Receptors, Cell Surface, Mice, SCID, General Biochemistry, Genetics and Molecular Biology, Histones, Mice, Phosphatidylinositol 3-Kinases, 03 medical and health sciences, Histone H3, 0302 clinical medicine, Cell Line, Tumor, Neoplasms, Animals, Humans, Protein kinase B, PI3K/AKT/mTOR pathway, Cell Proliferation, Phosphoinositide-3 Kinase Inhibitors, biology, Chemistry, HCT116 Cells, Xenograft Model Antitumor Assays, Bromodomain, Histone Deacetylase Inhibitors, 030104 developmental biology, Histone, Drug Resistance, Neoplasm, Acetylation, biology.protein, Cancer research, Histone deacetylase, Proto-Oncogene Proteins c-akt, 030217 neurology & neurosurgery
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b4bef44299ade56993f92e5dd28e481
https://doi.org/10.1016/j .celrep.2021.108744 -
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المؤلفون: Anna Bashmakov, Mei Yan, S. R. Kwon, Hae-Rim Kim, Elhaum Khobahy, Jacob J. Orme, Deena Sajitharan, S. Nukala, Yujin Ye, V. Taneja, So Youn Min, Yong Du, Tianfu Wu, Chandra Mohan
المصدر: Clinical and Experimental Immunology. 172:217-227
مصطلحات موضوعية: Male, medicine.medical_specialty, medicine.medical_treatment, Immunology, Arthritis, Autoimmunity, Lymphocyte Activation, medicine.disease_cause, T-Lymphocytes, Regulatory, Proinflammatory cytokine, Interferon-gamma, Mice, Lectins, Internal medicine, medicine, Animals, Immunology and Allergy, IL-2 receptor, business.industry, Macrophages, Interleukin-17, Interleukin-2 Receptor alpha Subunit, NF-kappa B, FOXP3, Forkhead Transcription Factors, Original Articles, Macrophage Activation, medicine.disease, Arthritis, Experimental, beta-N-Acetylhexosaminidases, Interleukin-10, Interleukin 10, Endocrinology, Cytokine, Mice, Inbred DBA, Immunoglobulin G, CD4 Antigens, lipids (amino acids, peptides, and proteins), Collagen, Interleukin 17, Peptides, business
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المؤلفون: Cristina Arriens, Jessica M. Mayeux, Jack Hutcheson, Laurie S. Davis, Kamala Vanarsa, Anne B. Satterthwaite, Jacob J. Orme, Benjamin F. Chong, Yong Du, Chandra Mohan, So Youn Min, Azza Mutwally, Tianfu Wu, Li Li
المصدر: Clinical immunology (Orlando, Fla.). 169
مصطلحات موضوعية: 0301 basic medicine, Adult, Male, Mice, Inbred MRL lpr, ADAM10, Immunology, Blotting, Western, Gene Expression, Inflammation, Biology, ADAM17 Protein, Receptor tyrosine kinase, Article, Cell Line, 03 medical and health sciences, ADAM10 Protein, Young Adult, 0302 clinical medicine, immune system diseases, Proto-Oncogene Proteins, medicine, Immunology and Allergy, Animals, Humans, Lupus Erythematosus, Systemic, Receptor, skin and connective tissue diseases, Mice, Knockout, Systemic lupus erythematosus, AXL receptor tyrosine kinase, GAS6, Reverse Transcriptase Polymerase Chain Reaction, Macrophages, Receptor Protein-Tyrosine Kinases, Middle Aged, medicine.disease, Axl Receptor Tyrosine Kinase, Mice, Inbred C57BL, 030104 developmental biology, Ectodomain, 030220 oncology & carcinogenesis, biology.protein, Leukocytes, Mononuclear, Intercellular Signaling Peptides and Proteins, Female, medicine.symptom
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المؤلفون: Kamala Vanarsa, Yong Du, Jacob J. Orme, Anne B. Satterthwaite, Chandra Mohan, Tianfu Wu
المصدر: PLoS ONE
PLoS ONE, Vol 11, Iss 8, p e0161682 (2016)مصطلحات موضوعية: 0301 basic medicine, Male, lcsh:Medicine, Pathogenesis, medicine.disease_cause, Pathology and Laboratory Medicine, Biochemistry, Autoimmunity, Mice, White Blood Cells, Animal Cells, Transcriptional regulation, Leukocytes, Medicine and Health Sciences, Lupus Erythematosus, Systemic, Enzyme-Linked Immunoassays, lcsh:Science, skin and connective tissue diseases, Wnt Signaling Pathway, beta Catenin, Multidisciplinary, Systemic lupus erythematosus, biology, Wnt signaling pathway, Catenins, Animal Models, Intercellular Signaling Peptides and Proteins, Female, Cellular Types, Anatomy, Research Article, Beta-catenin, Follistatin-Related Proteins, Immune Cells, Immunology, Mice, Transgenic, Mouse Models, Research and Analysis Methods, Systemic Lupus Erythematosus, Autoimmune Diseases, 03 medical and health sciences, Model Organisms, Axin Protein, Rheumatology, medicine, Animals, Humans, Immunoassays, Lupus erythematosus, Blood Cells, Lupus Erythematosus, Macrophages, lcsh:R, Biology and Life Sciences, Proteins, Kidneys, Dendritic cell, Dendritic Cells, Cell Biology, Renal System, medicine.disease, Mice, Inbred C57BL, Wnt Proteins, Disease Models, Animal, Cytoskeletal Proteins, 030104 developmental biology, Gene Expression Regulation, Catenin, biology.protein, Immunologic Techniques, lcsh:Q, Clinical Immunology, Clinical Medicine, Gene Deletion, Spleen
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المؤلفون: Chandra Mohan, Jacob J. Orme
المصدر: Autoimmunity reviews. 11(5)
مصطلحات موضوعية: CD4-Positive T-Lymphocytes, Myeloid, Neutrophils, Immunology, Inflammation, Biology, medicine.disease_cause, Neutrophil Activation, Autoimmunity, Pathogenesis, Phagocytosis, immune system diseases, medicine, Catalogs as Topic, Cell Adhesion, Immunology and Allergy, Animals, Humans, Lupus Erythematosus, Systemic, skin and connective tissue diseases, Internet, Innate immune system, Systemic lupus erythematosus, Lupus erythematosus, Macrophages, Macrophage Activation, Acquired immune system, medicine.disease, Chemotaxis, Leukocyte, medicine.anatomical_structure, Cytokines, medicine.symptom, Inflammation Mediators
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