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المؤلفون: Svenja Sydor, Aalt Bast, Ger H. Koek, Christian Trautwein, Francisco Javier Cubero, Raúl J. Andrade, Miguel Eugenio Zoubek, María Isabel Lucena, MM Woitok, Lars P. Bechmann, Leonard J Nelson
المساهمون: RS: NUTRIM - R3 - Respiratory & Age-related Health, RS: NUTRIM - R2 - Liver and digestive health, Farmacologie en Toxicologie, RS: FSE UCV Adaptive responses in relation to health effect and safety of nutrition, Interne Geneeskunde, MUMC+: MA Maag Darm Lever (9)
المصدر: Journal of Pathology, 247(1), 110-122. Wiley
مصطلحات موضوعية: Male, 0301 basic medicine, Necrosis, medicine.medical_treatment, Medizin, Pharmacology, Liver transplantation, 0302 clinical medicine, MEDIATOR, Phosphorylation, POPULATION, ibuprofen, Mice, Knockout, Liver injury, education.field_of_study, OUTCOMES, Cell Death, NECROSIS, c-jun, VANISHING BILE-DUCT, Liver, RESPIRATION, Toxicity, 030211 gastroenterology & hepatology, Chemical and Drug Induced Liver Injury, medicine.symptom, Signal Transduction, STEVENS-JOHNSON-SYNDROME, HEPATOTOXICITY, Population, Pathology and Forensic Medicine, 03 medical and health sciences, HEPATITIS, medicine, Animals, Humans, Mitogen-Activated Protein Kinase 9, Mitogen-Activated Protein Kinase 8, education, Protein kinase B, business.industry, organic chemicals, liver failure, drug-induced liver injury (DILI), toxicity, Liver Failure, Acute, medicine.disease, Enzyme Activation, Mice, Inbred C57BL, Disease Models, Animal, 030104 developmental biology, Hepatocytes, Liver function, JNK, business
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المؤلفون: Klaas Nico Faber, Janette Heegsma, Svenja Sydor, Han Moshage, Karen van Eunen, Lars P Bechmann, Natalia Smith-Cortinez, Barbara M. Bakker, Sandra Alejandra Serna-Salas
المساهمون: Restoring Organ Function by Means of Regenerative Medicine (REGENERATE), Center for Liver, Digestive and Metabolic Diseases (CLDM), Lifestyle Medicine (LM), Groningen Institute for Gastro Intestinal Genetics and Immunology (3GI)
المصدر: Cells, Vol 9, Iss 2456, p 2456 (2020)
Cells, 9(11):2456. MDPI AG
Cells
Volume 9
Issue 11مصطلحات موضوعية: Liver Cirrhosis, DYNAMICS, 0301 basic medicine, Glutamine, INHIBITION, Mitochondria, Liver, Oxidative phosphorylation, Mitochondrion, Mitochondrial Dynamics, Article, Oxidative Phosphorylation, 03 medical and health sciences, 0302 clinical medicine, cell metabolism, Hepatic Stellate Cells, Extracellular, Animals, Humans, Glycolysis, lcsh:QH301-705.5, liver fibrosis, Organelle Biogenesis, Glutaminolysis, Chemistry, hemic and immune systems, General Medicine, Metabolism, Rats, Cell biology, mitochondria, Phenotype, 030104 developmental biology, mitochondrial fusion, lcsh:Biology (General), 030220 oncology & carcinogenesis, Hepatic stellate cell
وصف الملف: application/pdf
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3
المؤلفون: Klaas Nico Faber, Guido Gerken, Jan Best, Svenja Sydor, Francisco Javier Cubero, Han Moshage, Maria Isabel Fiel, Anna Dittrich, Paul Manka, Sarah Theurer, Diana Vetter, Alexander Dechêne, Lea van Buren, Suzan Schwertheim, Ali Saeed, Ali Canbay, Scott L. Friedman, Martin Schlattjan, Janette Heegsma, Hideo A. Baba, Lars P. Bechmann
المساهمون: Restoring Organ Function by Means of Regenerative Medicine (REGENERATE), Center for Liver, Digestive and Metabolic Diseases (CLDM), Groningen Institute for Gastro Intestinal Genetics and Immunology (3GI)
المصدر: Liver International, 40(9), 2172-2181. Wiley
مصطلحات موضوعية: DOWN-REGULATION, Cirrhosis, Carcinoma, Hepatocellular, PATHOGENESIS, Cholangitis, Sclerosing, Medizin, cholangiocellular carcinoma, HEPATOCARCINOGENESIS, DIAGNOSIS, Primary sclerosing cholangitis, ACTIVATION, 03 medical and health sciences, Mice, 0302 clinical medicine, Cholestasis, HEPATOCELLULAR-CARCINOMA, MANAGEMENT, Kruppel-Like Factor 6, Medicine, Animals, Humans, PROSTATE-CANCER PROGRESSION, Liver injury, Hepatology, business.industry, Liver Neoplasms, medicine.disease, Liver regeneration, digestive system diseases, KLF6, Bile Ducts, Intrahepatic, FXR, Bile Duct Neoplasms, Liver, 030220 oncology & carcinogenesis, Hepatocellular carcinoma, ACID, Cancer research, Hepatocytes, 030211 gastroenterology & hepatology, Steatosis, business, cholestasis
وصف الملف: application/pdf
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4
المؤلفون: Maria Isabel Fiel, Scott L. Friedman, Klaas Nico Faber, Virginia Hernández-Gea, Andreas Paul, Hideo A. Baba, Ali Canbay, Yujin Hoshida, Miguel Eugenio Zoubek, Julia Kälsch, Sami Jafoui, Francisco Javier Cubero, Paul Manka, Diana Vetter, Han Moshage, C Billie Bian, Lars P. Bechmann, Leonard J Nelson, Jan-Peter Sowa, Guido Gerken, Jan Best, Svenja Sydor
المساهمون: Center for Liver, Digestive and Metabolic Diseases (CLDM), Lifestyle Medicine (LM), Groningen Institute for Gastro Intestinal Genetics and Immunology (3GI), Restoring Organ Function by Means of Regenerative Medicine (REGENERATE), University of Zurich, Bechmann, Lars P, Liver Cell Biology
المصدر: Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Scientific Reports
Scientific Reports, 7(1):8119. Nature Publishing Group
Sydor, S, Manka, P, Best, J, Jafoui, S, Sowa, J-P, Zoubek, M E, Hernandez-Gea, V, Cubero, F J, Kälsch, J, Vetter, D, Fiel, M I, Hoshida, Y, Bian, C B, Nelson, L J, Moshage, H, Faber, K N, Paul, A, Baba, H A, Gerken, G, Friedman, S L, Canbay, A & Bechmann, L P 2017, ' Krüppel-like factor 6 is a transcriptional activator of autophagy in acute liver injury ', Scientific Reports, vol. 7, no. 1, pp. 8119 . https://doi.org/10.1038/s41598-017-08680-wمصطلحات موضوعية: 0301 basic medicine, DOWN-REGULATION, Transcription, Genetic, Medizin, PROTEIN, 0302 clinical medicine, KLF6 TUMOR-SUPPRESSOR, Genes, Tumor Suppressor, Carbon Tetrachloride, IN-VIVO, Multidisciplinary, Liver Neoplasms, digestive, oral, and skin physiology, PARTIAL-HEPATECTOMY, Hep G2 Cells, Liver regeneration, 3. Good health, medicine.anatomical_structure, KLF6, Liver, Hepatocyte, GROWTH, Medicine, 030211 gastroenterology & hepatology, Kruppel-Like Factor 6, medicine.drug, Transcriptional Activation, Carcinoma, Hepatocellular, Science, Acute Lung Injury, 610 Medicine & health, Biology, Article, 03 medical and health sciences, Mediator, REGENERATION, Cell Line, Tumor, medicine, Journal Article, Autophagy, Animals, Hepatectomy, Humans, Transcription factor, 10217 Clinic for Visceral and Transplantation Surgery, Acetaminophen, Cell Proliferation, 1000 Multidisciplinary, P53, HUMAN HEPATOCELLULAR-CARCINOMA, Liver Regeneration, Mice, Inbred C57BL, MICE, 030104 developmental biology, Gene Expression Regulation, Cancer research, Hepatocytes
وصف الملف: application/pdf; s41598-017-08680-w.pdf - application/pdf
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المؤلفون: Svenja Sydor, Lena Wingerter, Hideo A. Baba, Barbara Sitek, Guido Gerken, Ali Canbay, Alexander Carpinteiro, Erich Gulbins, Jan-Peter Sowa, Dominik A. Megger, Lars P. Bechmann, Sami Jafoui, Martin Schlattjan
المصدر: Molecular Metabolism, Vol 6, Iss 5, Pp 416-427 (2017)
Molecular Metabolismمصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Ceramide, lcsh:Internal medicine, Medizin, Mechanistic Target of Rapamycin Complex 2, Biology, Rictor, Mice, 03 medical and health sciences, chemistry.chemical_compound, Non-alcoholic Fatty Liver Disease, NAFLD, Internal medicine, Western diet, Genotype, Nonalcoholic fatty liver disease, Adipocytes, medicine, Animals, lcsh:RC31-1245, Molecular Biology, 030102 biochemistry & molecular biology, Cell Biology, respiratory system, medicine.disease, Sphingolipid, Mice, Inbred C57BL, Sphingomyelin Phosphodiesterase, 030104 developmental biology, Endocrinology, chemistry, Diet, Western, Original Article, lipids (amino acids, peptides, and proteins), Acid sphingomyelinase, Adipocyte hypertrophy, Sphingomyelin, Proto-Oncogene Proteins c-akt, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cac60bc3b0186382cc5764d40e3ee77f
https://www.ncbi.nlm.nih.gov/pubmed/28462076 -
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المؤلفون: Lars P. Bechmann, Ali Canbay, Aline Gottlieb
المصدر: Annals of Hepatology, Vol 17, Iss 3, Pp 341-342 (2018)
مصطلحات موضوعية: 0301 basic medicine, Nonalcoholic steatohepatitis, medicine.medical_specialty, Steatosis, Specialties of internal medicine, Disease, Carbohydrate metabolism, Chronic liver disease, Severity of Illness Index, digestive system, Bile Acids and Salts, 03 medical and health sciences, 0302 clinical medicine, Non-alcoholic Fatty Liver Disease, Risk Factors, Internal medicine, NAFLD, medicine, Animals, Humans, Microbiome, Hepatology, business.industry, Fatty liver, NASH, Insulin sensitivity, General Medicine, Prognosis, medicine.disease, digestive system diseases, Bile acids, Gastrointestinal Microbiome, 030104 developmental biology, Endocrinology, Liver, RC581-951, 030211 gastroenterology & hepatology, business, Biomarkers
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7
المؤلفون: Toru Suzuki, Junichi Ishida, Fengxia Ge, Derek LeRoith, Ursula E. Lang, Lars P. Bechmann, G.L. Patman, Despina Televantou, Youngmin A. Lee, Helen L. Reeves, Diana Vetter, Loranne Agius, Ryozo Nagai, Peri Kocabayoglu, Xiaosong Li, Shoshana Yakar, Scott L. Friedman, Gary J. Schwartz, Weijia Zhang, Kei Yiu Hui, Paul D. Berk, M. Isabel Fiel, Rebekka A. Hannivoort, Úrsula Muñoz
المصدر: Journal of Hepatology, 58(5), 1000-1006. ELSEVIER SCIENCE BV
Journal of Hepatologyمصطلحات موضوعية: Male, TRB3, medicine.medical_treatment, Medizin, PEPCK, PPARα, Cohort Studies, chemistry.chemical_compound, 0302 clinical medicine, Non-alcoholic Fatty Liver Disease, Adipocyte, PPAR-ALPHA, Glucose homeostasis, Insulin, TUMOR-SUPPRESSOR, Cells, Cultured, Mice, Knockout, 0303 health sciences, Gene knockdown, INSULIN-RESISTANCE, miRNA-10b, NONALCOHOLIC STEATOHEPATITIS, Fatty liver, CANCER, 3. Good health, KLF6, 030211 gastroenterology & hepatology, Phosphoenolpyruvate Carboxykinase (GTP), Signal Transduction, Transcriptional Activation, medicine.medical_specialty, PATHOPHYSIOLOGY, Kruppel-Like Transcription Factors, Biology, METABOLISM, Diet, High-Fat, Article, 03 medical and health sciences, Insulin resistance, Internal medicine, Proto-Oncogene Proteins, NAFLD, medicine, Kruppel-Like Factor 6, Animals, Humans, PPAR alpha, RNA, Messenger, 030304 developmental biology, FATTY LIVER-DISEASE, Hepatology, HUMAN HEPATOCELLULAR-CARCINOMA, nutritional and metabolic diseases, Lipid metabolism, medicine.disease, Lipid Metabolism, Fatty Liver, Mice, Inbred C57BL, Disease Models, Animal, MICE, Endocrinology, Glucose, chemistry, Steatosis, CD36
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8
المؤلفون: Scott L. Friedman, Lars P. Bechmann, Rebekka A. Hannivoort, Alastair D. Burt, Úrsula Muñoz, Youngmin A. Lee, Christopher P. Day, Luca Miele, Diana Vetter, Isabel Fiel, Loranne Agius, Laura Pascoe, Amalia Gastaldelli, Elisabetta Bugianesi, Mark Walker, Demetrio Ciociaro, Kei Y. Hui, G.L. Patman, Andrea Mari, Ursula E. Lee, Helen L. Reeves, Emma Buzzigoli
المصدر: Hepatology
Hepatology (Baltim. Md. : Online) 55 (2012): 1083–1093. doi:10.1002/hep.24793
info:cnr-pdr/source/autori:Bechmann, L.P.;Gastaldelli, A.;Vetter, D.;Patman, G.L.;Pascoe, L.;Hannivoort, R.A.;Lee, U.E.;Fiel, I.;Munoz, U.;Ciociaro, D.;Lee, Y.M.;Buzzigoli, E.;Miele, L.;Hui, K.Y.;Bugianesi, E.;Burt, A.D.;Day, C.P.;Mari, A.;Agius, L.;Walker, M.;Friedman, S.L.;Reeves, H.L./titolo:Glucokinase links Kruppel-like factor 6 to the regulation of hepatic insulin sensitivity in nonalcoholic fatty liver disease/doi:10.1002%2Fhep.24793/rivista:Hepatology (Baltim. Md. : Online)/anno:2012/pagina_da:1083/pagina_a:1093/intervallo_pagine:1083–1093/volume:55
Hepatology, 55(4), 1083-1093. Wileyمصطلحات موضوعية: Blood Glucose, Male, Biopsy, medicine.medical_treatment, Medizin, PROTEIN, TUMOR-SUPPRESSOR GENE, TRIGLYCERIDE LEVELS, Cohort Studies, 0302 clinical medicine, Non-alcoholic Fatty Liver Disease, Glucokinase, Nonalcoholic fatty liver disease, Glucose homeostasis, IN-VIVO, Mice, Knockout, PLASMA-GLUCOSE, 0303 health sciences, Glucokinase regulatory protein, biology, Fatty liver, Middle Aged, KLF6, Liver, N/A, HEXOKINASE ISOENZYMES, GROWTH, Female, 030211 gastroenterology & hepatology, Adult, medicine.medical_specialty, Genotype, Settore MED/12 - GASTROENTEROLOGIA, Kruppel-Like Transcription Factors, Article, 03 medical and health sciences, Insulin resistance, Proto-Oncogene Proteins, Internal medicine, Kruppel-Like Factor 6, medicine, Animals, Humans, RNA, Messenger, GENOME-WIDE ASSOCIATION, 030304 developmental biology, Polymorphism, Genetic, Hepatology, Insulin, medicine.disease, Fatty Liver, Mice, Inbred C57BL, Disease Models, Animal, MICE, Endocrinology, Hepatocytes, biology.protein, GLUCOSE-HOMEOSTASIS, Insulin Resistance
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المؤلفون: Juergen Thomale, Zaza Katsarava, Guido Gerken, Gerald Holtmann, Olivia Yepnjouo, Mark Obermann, M.-S. Yoon, Rupert Egensperger, Lars P. Bechmann
المصدر: Neuroscience Bulletin. 26:282-288
مصطلحات موضوعية: Male, medicine.medical_specialty, Sensory Receptor Cells, Colon, Physiology, medicine.medical_treatment, Medizin, Pharmacology, Neuroprotection, Mice, Random Allocation, Microscopy, Electron, Transmission, Ganglia, Spinal, Physical Stimulation, medicine, Animals, Humans, Erythropoietin, Saline, Cisplatin, Analysis of Variance, Behavior, Animal, Electromyography, business.industry, General Neuroscience, Rectum, General Medicine, Hyperplasia, medicine.disease, Recombinant Proteins, Surgery, Mice, Inbred C57BL, Disease Models, Animal, Viscera, Autonomic nervous system, Peripheral neuropathy, Hyperalgesia, Original Article, medicine.symptom, business, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22514931844d3c1f165e3b22aab81149
https://doi.org/10.1007/s12264-010-0413-6 -
10
المؤلفون: Lars P. Bechmann, Stefan Landgraeber, Martin Schlattjan, Martin Tötsch, Marcus Jäger, Ali Canbay, S. Putz, Gero Hilken, Florian Grabellus
مصطلحات موضوعية: Adult, Male, Pathology, medicine.medical_specialty, animal structures, Osteolysis, Arthroplasty, Replacement, Hip, Biomedical Engineering, Medizin, Apoptosis, Inflammation, Models, Biological, Biochemistry, Biomaterials, Phagocytosis, In Situ Nick-End Labeling, medicine, Animals, Humans, Molecular Biology, Cells, Cultured, Aged, Aged, 80 and over, TUNEL assay, Adiponectin, business.industry, Macrophages, Skull, General Medicine, Middle Aged, medicine.disease, Pathophysiology, Prosthesis Failure, Mice, Inbred C57BL, Disease Models, Animal, Knockout mouse, Immunohistochemistry, Female, Receptors, Adiponectin, medicine.symptom, business, Joint Capsule, hormones, hormone substitutes, and hormone antagonists, Biotechnology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cef04a0fbebc60ec7bab4ed38ae825d0
https://www.ncbi.nlm.nih.gov/pubmed/23994269
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