المؤلفون: Bi Y; Oncology Center, Zhujiang Hospital of Southern Medical University, Guangzhou, Guangdong 510280, China; Department of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Verginadis II; Department of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Dey S; Department of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Lin L; MD Anderson Cancer Center, Division of Radiation Oncology, Houston, TX 77054, USA., Guo L; Oncology Center, Zhujiang Hospital of Southern Medical University, Guangzhou, Guangdong 510280, China., Zheng Y; Oncology Center, Zhujiang Hospital of Southern Medical University, Guangzhou, Guangdong 510280, China. Electronic address: zyfcn@yahoo.com., Koumenis C; Department of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address: costas.koumenis@uphs.upenn.edu.

المصدر: Gynecologic oncology [Gynecol Oncol] 2018 Sep; Vol. 150 (3), pp. 534-544. Date of Electronic Publication: 2018 Jul 17.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Academic Press Country of Publication: United States NLM ID: 0365304 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-6859 (Electronic) Linking ISSN: 00908258 NLM ISO Abbreviation: Gynecol Oncol Subsets: MEDLINE

مواضيع طبية MeSH: Genes, BRCA1*, Antineoplastic Agents/*pharmacology , Neoplasms, Cystic, Mucinous, and Serous/*drug therapy , Ovarian Neoplasms/*drug therapy , Phthalazines/*pharmacology , Piperazines/*pharmacology , Radiation Tolerance/*drug effects, Animals ; Antineoplastic Agents/therapeutic use ; Apoptosis/drug effects ; Cell Line, Tumor ; Cell Proliferation/drug effects ; DNA Damage/drug effects ; DNA Repair/drug effects ; Female ; Humans ; Mice ; Neoplasm Grading ; Neoplasm Transplantation ; Neoplasms, Cystic, Mucinous, and Serous/genetics ; Neoplasms, Cystic, Mucinous, and Serous/radiotherapy ; Ovarian Neoplasms/genetics ; Ovarian Neoplasms/radiotherapy ; Phthalazines/therapeutic use ; Piperazines/therapeutic use ; Poly (ADP-Ribose) Polymerase-1/antagonists & inhibitors

المؤلفون: Ma XH, Piao SF, Dey S, McAfee Q, Karakousis G, Villanueva J, Hart LS, Levi S, Hu J, Zhang G, Lazova R, Klump V, Pawelek JM, Xu X, Xu W, Schuchter LM, Davies MA, Herlyn M, Winkler J, Koumenis C, Amaravadi RK

المصدر: The Journal of clinical investigation [J Clin Invest] 2014 Mar; Vol. 124 (3), pp. 1406-17. Date of Electronic Publication: 2014 Feb 24.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents/*pharmacology , Autophagy/*drug effects , Endoplasmic Reticulum Stress/*drug effects , Indoles/*pharmacology , Melanoma/*drug therapy , Proto-Oncogene Proteins B-raf/*antagonists & inhibitors , Sulfonamides/*pharmacology, Animals ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Drug Resistance, Neoplasm/drug effects ; Endoplasmic Reticulum Chaperone BiP ; Humans ; MAP Kinase Signaling System ; Melanoma/genetics ; Melanoma/pathology ; Mice ; Mice, Nude ; Mutation, Missense ; Proto-Oncogene Proteins B-raf/genetics ; Proto-Oncogene Proteins B-raf/metabolism ; Vemurafenib ; Xenograft Model Antitumor Assays

المؤلفون: Tuttle S; Department of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Hertan L, Daurio N, Porter S, Kaushick C, Li D, Myamoto S, Lin A, O'Malley BW, Koumenis C

المصدر: Cancer biology & therapy [Cancer Biol Ther] 2012 May; Vol. 13 (7), pp. 575-84. Date of Electronic Publication: 2012 May 01.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101137842 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1555-8576 (Electronic) Linking ISSN: 15384047 NLM ISO Abbreviation: Cancer Biol Ther Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents/*pharmacology , Carcinoma, Squamous Cell/*virology , Curcumin/*pharmacology , Head and Neck Neoplasms/*virology , Papillomaviridae/*genetics , Radiation Tolerance/*drug effects , Radiation-Sensitizing Agents/*pharmacology, Animals ; Antineoplastic Agents/administration & dosage ; Carcinoma, Squamous Cell/drug therapy ; Carcinoma, Squamous Cell/mortality ; Carcinoma, Squamous Cell/radiotherapy ; Cell Line, Tumor ; Chemoprevention ; Curcumin/administration & dosage ; Disease Models, Animal ; Head and Neck Neoplasms/drug therapy ; Head and Neck Neoplasms/mortality ; Head and Neck Neoplasms/radiotherapy ; Humans ; Mice ; Mice, Nude ; Radiation-Sensitizing Agents/administration & dosage ; Thioredoxin Reductase 1/genetics ; Thioredoxin Reductase 1/metabolism

المؤلفون: Hart LS; Department of Radiation Oncology, University of Pennsylvania School of Medicine, Philadelphia, PA, USA., Dolloff NG, Dicker DT, Koumenis C, Christensen JG, Grimberg A, El-Deiry WS

المصدر: Cell cycle (Georgetown, Tex.) [Cell Cycle] 2011 Jul 15; Vol. 10 (14), pp. 2331-8. Date of Electronic Publication: 2011 Jul 15.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101137841 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1551-4005 (Electronic) Linking ISSN: 15514005 NLM ISO Abbreviation: Cell Cycle Subsets: MEDLINE

مواضيع طبية MeSH: Antibodies, Monoclonal/*pharmacology , Antineoplastic Agents/*pharmacology , Colonic Neoplasms/*pathology , Insulin-Like Growth Factor I/*pharmacology , Neoplastic Stem Cells/*drug effects, Animals ; Cell Line, Tumor ; Humans ; Immunoglobulins, Intravenous ; Mice ; Mice, Nude ; Neoplastic Stem Cells/cytology ; Proto-Oncogene Proteins c-akt/antagonists & inhibitors ; Proto-Oncogene Proteins c-akt/metabolism ; RNA Interference ; RNA, Small Interfering/metabolism ; Receptor, IGF Type 1/antagonists & inhibitors ; Receptor, IGF Type 1/immunology ; Receptor, IGF Type 1/metabolism ; Transplantation, Heterologous ; beta Catenin/antagonists & inhibitors ; beta Catenin/genetics ; beta Catenin/metabolism

المؤلفون: Javvadi P; Department of Cancer Biology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA., Hertan L, Kosoff R, Datta T, Kolev J, Mick R, Tuttle SW, Koumenis C

المصدر: Cancer research [Cancer Res] 2010 Mar 01; Vol. 70 (5), pp. 1941-50. Date of Electronic Publication: 2010 Feb 16.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-7445 (Electronic) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents/*pharmacology , Carcinoma, Squamous Cell/*drug therapy , Carcinoma, Squamous Cell/*radiotherapy , Curcumin/*pharmacology , Radiation-Sensitizing Agents/*pharmacology , Thioredoxin Reductase 1/*biosynthesis, Apoptosis/drug effects ; Carcinoma, Squamous Cell/enzymology ; Cell Transformation, Neoplastic/metabolism ; Enzyme Activation ; Gene Knockdown Techniques ; HeLa Cells ; Humans ; Mitogen-Activated Protein Kinase 1/metabolism ; Mitogen-Activated Protein Kinase 3/metabolism ; Reactive Oxygen Species/metabolism ; Thioredoxin Reductase 1/antagonists & inhibitors ; Thioredoxin Reductase 1/deficiency ; Thioredoxin Reductase 1/genetics

المؤلفون: Fels DR; Department of Radiation Oncology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104-6072, USA., Ye J, Segan AT, Kridel SJ, Spiotto M, Olson M, Koong AC, Koumenis C

المصدر: Cancer research [Cancer Res] 2008 Nov 15; Vol. 68 (22), pp. 9323-30.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print Cited Medium: Internet ISSN: 1538-7445 (Electronic) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents/*pharmacology , Boronic Acids/*pharmacology , Endoplasmic Reticulum/*drug effects , Protease Inhibitors/*pharmacology , Pyrazines/*pharmacology , Stress, Physiological/*drug effects, Activating Transcription Factor 4/genetics ; Apoptosis ; Autophagy ; Bortezomib ; Cell Hypoxia ; Cell Line, Tumor ; DNA-Binding Proteins/genetics ; Endoplasmic Reticulum/metabolism ; Humans ; Microtubule-Associated Proteins/metabolism ; Necrosis ; Protein Folding ; Regulatory Factor X Transcription Factors ; Signal Transduction ; Thapsigargin/pharmacology ; Transcription Factors/genetics

المؤلفون: Park MA; Department of Biochemistry and Molecular Biology, Virginia Commonwealth University, Richmond, Virginia, USA., Curiel DT, Koumenis C, Graf M, Chen CS, Fisher PB, Grant S, Dent P

المصدر: Autophagy [Autophagy] 2008 Apr; Vol. 4 (3), pp. 364-7. Date of Electronic Publication: 2008 Jan 17.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101265188 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1554-8635 (Electronic) Linking ISSN: 15548627 NLM ISO Abbreviation: Autophagy Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents/*pharmacology , Autophagy/*physiology , Cell Transformation, Neoplastic/*drug effects , HSP70 Heat-Shock Proteins/*biosynthesis , Pyrazoles/*pharmacology , Sulfonamides/*pharmacology , eIF-2 Kinase/*physiology, Animals ; Apoptosis Inducing Factor/metabolism ; Autophagy/drug effects ; Autophagy-Related Protein 5 ; Cathepsin B/physiology ; Cell Line, Tumor ; Endoplasmic Reticulum/enzymology ; Endoplasmic Reticulum Chaperone BiP ; Fibroblasts/drug effects ; Fibroblasts/physiology ; Gene Expression Regulation, Neoplastic ; HSP90 Heat-Shock Proteins/biosynthesis ; Humans ; Lysosomes/metabolism ; Mice ; Microtubule-Associated Proteins/biosynthesis ; Signal Transduction ; eIF-2 Kinase/genetics

المؤلفون: Rao A; Department of Cancer Biology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157, USA., Coan A, Welsh JE, Barclay WW, Koumenis C, Cramer SD

المصدر: Cancer research [Cancer Res] 2004 Mar 15; Vol. 64 (6), pp. 2143-7.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print Cited Medium: Print ISSN: 0008-5472 (Print) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents/*therapeutic use , Calcitriol/*therapeutic use , Cyclins/*metabolism , Genistein/*therapeutic use , Prostatic Neoplasms/*drug therapy , Receptors, Calcitriol/*metabolism, Calcium Channel Agonists/therapeutic use ; Cyclin-Dependent Kinase Inhibitor p21 ; Cyclins/antagonists & inhibitors ; Cyclins/genetics ; Drug Synergism ; Enzyme Inhibitors/metabolism ; Humans ; Male ; Prostatic Neoplasms/metabolism ; Prostatic Neoplasms/pathology ; RNA, Small Interfering/pharmacology ; Tumor Cells, Cultured ; Up-Regulation

المؤلفون: Giaccia AJ, Brown JM, Wouters B, Denko N, Koumenis C

المصدر: Science (New York, N.Y.) [Science] 1998 Jan 02; Vol. 279 (5347), pp. 12-3.

نوع المنشور: Comment; Letter

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print Cited Medium: Print ISSN: 0036-8075 (Print) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE

مواضيع طبية MeSH: Drug Screening Assays, Antitumor*, Antineoplastic Agents/*therapeutic use , Neoplasms/*drug therapy, Animals ; Disease Models, Animal ; Neoplasm Transplantation ; Neoplasms/pathology ; Neoplasms/physiopathology ; Transplantation, Heterologous ; Tumor Stem Cell Assay

المؤلفون: Bhattacharya, S, HuangFu, W-C, Dong, G, Qian, J, Baker, D P, Karar, J, Koumenis, C, Diehl, J A, Fuchs, S Y

المصدر: Oncogene; 9/5/2013, Vol. 32 Issue 36, p4214-4221, 8p, 4 Graphs

مصطلحات موضوعية: ANTINEOPLASTIC agents, INTERFERON receptors, PROTEIN kinases, PHOSPHORYLATION, HYPOXEMIA, TRANSLATION initiation factors (Biochemistry), BREAST cancer