المؤلفون: Garcia AA; 1University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA 90033, USA., Muggia FM, Spears CP, Jeffers S, Silberman H, Pujari M, Koda RT

المصدر: Anti-cancer drugs [Anticancer Drugs] 2001 Jul; Vol. 12 (6), pp. 505-11.

نوع المنشور: Clinical Trial; Clinical Trial, Phase I; Journal Article; Research Support, U.S. Gov't, P.H.S.

بيانات الدورية: Publisher: Lippincott Williams & Wilkins Country of Publication: England NLM ID: 9100823 Publication Model: Print Cited Medium: Print ISSN: 0959-4973 (Print) Linking ISSN: 09594973 NLM ISO Abbreviation: Anticancer Drugs Subsets: MEDLINE

مواضيع طبية MeSH: Antimetabolites, Antineoplastic/*administration & dosage , Antineoplastic Agents/*administration & dosage , Antineoplastic Combined Chemotherapy Protocols/*therapeutic use , Floxuridine/*administration & dosage , Hydroxyurea/*administration & dosage , Leucovorin/*administration & dosage, Adult ; Aged ; Aged, 80 and over ; Area Under Curve ; Female ; Humans ; Injections, Intraperitoneal ; Injections, Intravenous ; Male ; Maximum Tolerated Dose ; Middle Aged ; Neoplasms/drug therapy ; Time Factors

المؤلفون: Carlsson G; Department of Surgery, Ostra Sjukhuset, Göteborg, Sweden., Gustavsson B, Frösing R, Odin E, Hafström LO, Spears CP, Larsson PA

المصدر: Biochemical pharmacology [Biochem Pharmacol] 1995 Oct 26; Vol. 50 (9), pp. 1347-51.

نوع المنشور: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

بيانات الدورية: Publisher: Elsevier Science Country of Publication: England NLM ID: 0101032 Publication Model: Print Cited Medium: Print ISSN: 0006-2952 (Print) Linking ISSN: 00062952 NLM ISO Abbreviation: Biochem Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Antimetabolites, Antineoplastic/*pharmacology , Antineoplastic Combined Chemotherapy Protocols/*pharmacology , Colonic Neoplasms/*drug therapy , Fluorouracil/*pharmacology , Leucovorin/*pharmacology , Liver Neoplasms, Experimental/*drug therapy, Animals ; Antimetabolites, Antineoplastic/administration & dosage ; Antimetabolites, Antineoplastic/toxicity ; Cell Division/drug effects ; Colonic Neoplasms/enzymology ; Colonic Neoplasms/pathology ; Disease Models, Animal ; Enzyme Inhibitors/pharmacology ; Fluorouracil/administration & dosage ; Fluorouracil/toxicity ; Leucovorin/administration & dosage ; Leucovorin/toxicity ; Liver Neoplasms, Experimental/enzymology ; Liver Neoplasms, Experimental/pathology ; Male ; Neoplasm Transplantation ; Random Allocation ; Rats ; Rats, Wistar ; Stereoisomerism ; Thymidylate Synthase/antagonists & inhibitors ; Thymidylate Synthase/metabolism

المؤلفون: Leichman L; Department of Medicine, University of Southern California, USA., Lenz HJ, Leichman CG, Groshen S, Danenberg K, Baranda J, Spears CP, Boswell W, Silberman H, Ortega A, et. al.

المصدر: European journal of cancer (Oxford, England : 1990) [Eur J Cancer] 1995 Jul-Aug; Vol. 31A (7-8), pp. 1306-10.

نوع المنشور: Clinical Trial; Journal Article; Research Support, U.S. Gov't, P.H.S.

بيانات الدورية: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9005373 Publication Model: Print Cited Medium: Print ISSN: 0959-8049 (Print) Linking ISSN: 09598049 NLM ISO Abbreviation: Eur J Cancer Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Combined Chemotherapy Protocols/*therapeutic use , Biomarkers, Tumor/*metabolism , Colorectal Neoplasms/*drug therapy , Thymidylate Synthase/*metabolism, Adult ; Aged ; Aged, 80 and over ; Antidotes/administration & dosage ; Antimetabolites, Antineoplastic/administration & dosage ; Base Sequence ; Colorectal Neoplasms/enzymology ; Female ; Fluorouracil/administration & dosage ; Gene Expression ; Humans ; Leucovorin/administration & dosage ; Male ; Middle Aged ; Molecular Sequence Data

المؤلفون: Muggia FM; Department of Medicine, University of Southern California, Los Angeles 90033., Tulpule A, Retzios A, Chen F, Jeffers S, Leichman CG, Leichman L, Spears CP, Chan KK

المصدر: Investigational new drugs [Invest New Drugs] 1994; Vol. 12 (3), pp. 197-206.

نوع المنشور: Clinical Trial; Clinical Trial, Phase II; Journal Article; Research Support, U.S. Gov't, P.H.S.

بيانات الدورية: Publisher: Springer Country of Publication: United States NLM ID: 8309330 Publication Model: Print Cited Medium: Print ISSN: 0167-6997 (Print) Linking ISSN: 01676997 NLM ISO Abbreviation: Invest New Drugs Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Combined Chemotherapy Protocols/*therapeutic use , Floxuridine/*pharmacokinetics , Leucovorin/*pharmacokinetics , Peritoneal Neoplasms/*secondary, Abdominal Neoplasms/drug therapy ; Antineoplastic Combined Chemotherapy Protocols/pharmacokinetics ; Drug Administration Schedule ; Female ; Floxuridine/administration & dosage ; Floxuridine/adverse effects ; Half-Life ; Humans ; Infusions, Parenteral ; Leucovorin/administration & dosage ; Male ; Metabolic Clearance Rate ; Peritoneal Neoplasms/drug therapy

المؤلفون: Leichman L; University of Southern California School of Medicine and Medical Center, Los Angeles., Silberman H, Leichman CG, Spears CP, Ray M, Muggia FM, Kiyabu M, Radin R, Laine L, Stain S, et. al.

المصدر: Journal of clinical oncology : official journal of the American Society of Clinical Oncology [J Clin Oncol] 1992 Dec; Vol. 10 (12), pp. 1933-42.

نوع المنشور: Clinical Trial; Clinical Trial, Phase II; Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Society of Clinical Oncology Country of Publication: United States NLM ID: 8309333 Publication Model: Print Cited Medium: Print ISSN: 0732-183X (Print) Linking ISSN: 0732183X NLM ISO Abbreviation: J Clin Oncol Subsets: MEDLINE

مواضيع طبية MeSH: Adenocarcinoma/*drug therapy , Antineoplastic Combined Chemotherapy Protocols/*therapeutic use , Stomach Neoplasms/*drug therapy, Adenocarcinoma/surgery ; Adult ; Aged ; Antineoplastic Combined Chemotherapy Protocols/administration & dosage ; Antineoplastic Combined Chemotherapy Protocols/adverse effects ; Chemotherapy, Adjuvant ; Cisplatin/administration & dosage ; Drug Administration Schedule ; Feasibility Studies ; Female ; Floxuridine/administration & dosage ; Fluorouracil/administration & dosage ; Humans ; Infusions, Intravenous ; Infusions, Parenteral ; Leucovorin/administration & dosage ; Male ; Middle Aged ; Pilot Projects ; Stomach Neoplasms/surgery ; Survival Analysis ; Treatment Outcome

المؤلفون: Carlsson G; Department of Surgery, Ostra Sjukhuset, Göteborg, Sweden., Gustavsson BG, Spears CP, Hafström LO

المصدر: Anticancer research [Anticancer Res] 1990 May-Jun; Vol. 10 (3), pp. 813-6.

نوع المنشور: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

بيانات الدورية: Publisher: International Institute of Anticancer Research Country of Publication: Greece NLM ID: 8102988 Publication Model: Print Cited Medium: Print ISSN: 0250-7005 (Print) Linking ISSN: 02507005 NLM ISO Abbreviation: Anticancer Res Subsets: MEDLINE

مواضيع طبية MeSH: Adenocarcinoma/*drug therapy , Antineoplastic Combined Chemotherapy Protocols/*therapeutic use , Colonic Neoplasms/*drug therapy , Fluorouracil/*therapeutic use , Leucovorin/*therapeutic use , Liver Neoplasms/*secondary, Animals ; Fluorouracil/administration & dosage ; Leucovorin/administration & dosage ; Liver Neoplasms/drug therapy ; Rats ; Rats, Inbred Strains

المؤلفون: Leichman CG; Division of Medical Oncology, University of Southern California, Los Angeles 90033., Leichman L, Spears CP, Rosen PJ, Muggia F, Jeffers S, Waugh W

المصدر: Cancer chemotherapy and pharmacology [Cancer Chemother Pharmacol] 1990; Vol. 26 (1), pp. 57-61.

نوع المنشور: Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

بيانات الدورية: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 7806519 Publication Model: Print Cited Medium: Print ISSN: 0344-5704 (Print) Linking ISSN: 03445704 NLM ISO Abbreviation: Cancer Chemother Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Combined Chemotherapy Protocols/*therapeutic use , Gastrointestinal Neoplasms/*drug therapy, Aged ; Antineoplastic Combined Chemotherapy Protocols/adverse effects ; Carcinoembryonic Antigen/analysis ; Clinical Trials as Topic ; Drug Administration Schedule ; Drug Evaluation ; Female ; Fluorouracil/administration & dosage ; Gastrointestinal Neoplasms/immunology ; Gastrointestinal Neoplasms/pathology ; Humans ; Leucovorin/administration & dosage ; Male ; Middle Aged ; Neoplasm Metastasis/prevention & control