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1
المؤلفون: Xin-Chen Jiang, Fang-Hai Tu, Li-Yuan Wei, Bo-Zheng Wang, Hao Yuan, Jing-Mei Yuan, Yong Rao, Shi-Liang Huang, Qing-Jiang Li, Tian-Miao Ou, Hong-Gen Wang, Jia-Heng Tan, Shuo-Bin Chen, Zhi-Shu Huang
المصدر: Journal of Medicinal Chemistry. 65:12346-12366
مصطلحات موضوعية: Histone Deacetylase Inhibitors, Zinc, Cell Line, Tumor, Drug Discovery, Humans, Molecular Medicine, Antineoplastic Agents, Apoptosis, Triple Negative Breast Neoplasms, DNA, Xenograft Model Antitumor Assays, Histone Deacetylases, Cell Proliferation
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2
المؤلفون: Shi-Liang Huang, Qi-Kun Yin, Jia-En Wang, Honggen Wang, Ding Li, Chen-Xi Wang, Jia-Heng Tan, Zhi-Shu Huang, Yao-Hao Xu, Yong Rao, Zi-Lin Zhang, Shuo-Bin Chen, Tian-Miao Ou, Jia-Li Tu, Qingjiang Li
المصدر: Journal of Medicinal Chemistry. 63:9752-9772
مصطلحات موضوعية: Models, Molecular, congenital, hereditary, and neonatal diseases and abnormalities, Protein Conformation, DNA damage, Poly ADP ribose polymerase, Apoptosis, Chemistry Techniques, Synthetic, Poly(ADP-ribose) Polymerase Inhibitors, 01 natural sciences, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, Drug Discovery, Humans, Polymerase, Cell Proliferation, Quinazolinones, 030304 developmental biology, 0303 health sciences, RecQ Helicases, biology, urogenital system, Chemistry, nutritional and metabolic diseases, Helicase, Drug Synergism, Telomere, HCT116 Cells, 0104 chemical sciences, Cell biology, 010404 medicinal & biomolecular chemistry, Bloom syndrome protein, Drug Design, Cancer cell, biology.protein, Molecular Medicine, DNA, DNA Damage
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3
المؤلفون: Pei-Fen Yao, Jie-Bin Ou, Du-Chao Zhou, Honggen Wang, Zhi-Shu Huang, Hua-Ting Xie, Cheng-Cheng Liang, Shi-Liang Huang, Shuo-Bin Chen, Yan-Wen Mai
المصدر: Bioorganic chemistry. 114
مصطلحات موضوعية: Stereochemistry, Antineoplastic Agents, Apoptosis, 01 natural sciences, Biochemistry, Structure-Activity Relationship, Cell Line, Tumor, Drug Discovery, medicine, Bioassay, Potency, Humans, Topoisomerase II Inhibitors, Cytotoxicity, Poly-ADP-Ribose Binding Proteins, Molecular Biology, IC50, Etoposide, Cell Proliferation, biology, Dose-Response Relationship, Drug, Molecular Structure, 010405 organic chemistry, Chemistry, Topoisomerase, Organic Chemistry, In vitro, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, DNA Topoisomerases, Type II, Cell culture, biology.protein, Drug Screening Assays, Antitumor, medicine.drug
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4
المؤلفون: Pei-Fen Yao, Shi-Liang Huang, Chen Zhang, Yu-Ting Lu, Zhi-Shu Huang, Yan-Wen Mai, Du-Chao Zhou, Jie Xia, Honggen Wang
المصدر: Bioorganic chemistry. 91
مصطلحات موضوعية: Stereochemistry, Antineoplastic Agents, Apoptosis, 01 natural sciences, Biochemistry, HeLa, chemistry.chemical_compound, Structure-Activity Relationship, Cell Line, Tumor, Drug Discovery, Humans, Topoisomerase II Inhibitors, Binding site, Cytotoxicity, Molecular Biology, Cell Proliferation, Binding Sites, biology, Molecular Structure, 010405 organic chemistry, Topoisomerase, Aryl, Organic Chemistry, Quinones, Cell cycle, biology.organism_classification, 0104 chemical sciences, Molecular Docking Simulation, 010404 medicinal & biomolecular chemistry, DNA Topoisomerases, Type II, chemistry, Cell culture, Drug Design, biology.protein, Quinazolines, Drug Screening Assays, Antitumor, Protein Binding
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5
المؤلفون: Zhi-Shu Huang, Tian-Miao Ou, Shi-Liang Huang, Zi-Lin Zhang, Yu-Qing Wang, Honggen Wang, Jia-Heng Tan, Shuo-Bin Chen, Ding Li, Qi-Kun Yin, Qian-Liang Guo, Chen-Xi Wang
المصدر: Journal of medicinal chemistry. 62(6)
مصطلحات موضوعية: congenital, hereditary, and neonatal diseases and abnormalities, DNA damage, RAD51, Apoptosis, 01 natural sciences, 03 medical and health sciences, chemistry.chemical_compound, Alkaloids, Drug Discovery, Humans, DNA Breaks, Double-Stranded, Enzyme Inhibitors, 030304 developmental biology, Cell Proliferation, 0303 health sciences, biology, RecQ Helicases, urogenital system, Drug discovery, nutritional and metabolic diseases, Helicase, Recombinational DNA Repair, DNA, HCT116 Cells, 0104 chemical sciences, Cell biology, 010404 medicinal & biomolecular chemistry, chemistry, Bloom syndrome protein, Cancer cell, biology.protein, Quinazolines, Molecular Medicine, Rad51 Recombinase, Homologous recombination
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6
المؤلفون: Jia-Heng Tan, Yan-Wen Mai, Shi-Liang Huang, Pei-Fen Yao, Peng-Hui Li, Shuo-Bin Chen, Zhi-Shu Huang, Ping Zeng, Ding Li, Tian-Miao Ou, Lian-Quan Gu
المصدر: Journal of medicinal chemistry. 59(1)
مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, Pyrazine, Stereochemistry, Antineoplastic Agents, Apoptosis, 01 natural sciences, Catalysis, 03 medical and health sciences, chemistry.chemical_compound, Structure-Activity Relationship, Cell Line, Tumor, Drug Discovery, Structure–activity relationship, Humans, Topoisomerase II Inhibitors, Pyrroles, Binding site, Cell Proliferation, biology, 010405 organic chemistry, Cell growth, Receptors, Purinergic P2, Topoisomerase, DNA Helicases, DNA, 0104 chemical sciences, Molecular Docking Simulation, 030104 developmental biology, DNA Topoisomerases, Type II, chemistry, Cell culture, Pyrazines, biology.protein, Molecular Medicine, Topoisomerase-II Inhibitor, Drug Screening Assays, Antitumor
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7
المؤلفون: Lian-Quan Gu, Zhi-Shu Huang, Shi-Liang Huang, Zhong Liu, Man-Mei Li, Kin Sing Lee
المصدر: Chemico-Biological Interactions. 177:48-57
مصطلحات موضوعية: Thioredoxin-Disulfide Reductase, Thioredoxin reductase, Intracellular Space, Antineoplastic Agents, Apoptosis, Toxicology, HeLa, Necrosis, chemistry.chemical_compound, Superoxides, Oxidoreductase, Humans, Enzyme Inhibitors, Cell Proliferation, chemistry.chemical_classification, biology, Superoxide, Cell growth, Cell Cycle, Cytochromes c, NADPH Oxidases, General Medicine, Flow Cytometry, biology.organism_classification, Kinetics, chemistry, Biochemistry, Drug Screening Assays, Antitumor, Thioredoxin, Reactive Oxygen Species, Sesquiterpenes, Intracellular, HeLa Cells, Naphthoquinones
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8
المؤلفون: Lin-Kun An, Tian-Miao Ou, Zhi-Shu Huang, Lian-Quan Gu, Ming-Hao Hu, Pei-Fen Yao, Jia-Heng Tan, Shi-Tian Zhuo, Shi-Liang Huang, Chun-Yan Li, Shuo-Bin Chen, Ding Li
المصدر: Organicbiomolecular chemistry. 11(24)
مصطلحات موضوعية: Models, Molecular, medicine.drug_class, Stereochemistry, Phenazine, Antineoplastic Agents, Apoptosis, HL-60 Cells, Cleavage (embryo), Biochemistry, HeLa, chemistry.chemical_compound, Structure-Activity Relationship, Cell Line, Tumor, medicine, Structure–activity relationship, Humans, Topoisomerase II Inhibitors, Physical and Theoretical Chemistry, Cell Proliferation, biology, Dose-Response Relationship, Drug, Topoisomerase, Organic Chemistry, DNA replication, biology.organism_classification, Recombinant Proteins, DNA Topoisomerases, Type II, chemistry, DNA Topoisomerases, Type I, biology.protein, MCF-7 Cells, Phenazines, Drug Screening Assays, Antitumor, Topoisomerase I Inhibitors, DNA, Topoisomerase inhibitor, HeLa Cells
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc1ea4d3ee3dca468b99c9c43e09e638
https://pubmed.ncbi.nlm.nih.gov/23657605 -
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المؤلفون: Zhi-Shu Huang, Chen Xi, Lin-Kun An, Ding Li, Zeng Li, Lian-Quan Gu, Tian-Miao Ou, Xiaodong Wang, Jia-Heng Tan, Shi-Liang Huang, Zheng Xu, Yu-Jing Lu
المصدر: Journal of medicinal chemistry. 53(11)
مصطلحات موضوعية: Indoles, Transcription, Genetic, Direct evidence, Apoptosis, HL-60 Cells, Ligands, Polymerase Chain Reaction, Alkaloids, Transcription (biology), Drug Discovery, Hydroxides, Humans, heterocyclic compounds, Promoter Regions, Genetic, Gene, Transcriptional activity, Oncogene, Base Sequence, Chemistry, Promoter, Quindoline, Molecular biology, Genes, bcl-2, G-Quadruplexes, Transcriptional Repressor, Quinolines, Molecular Medicine, Thermodynamics