نتائج البحث - "Alvaro Aytes"

1

Loss of TGFβ signaling increases alternative end-joining DNA repair that sensitizes to genotoxic therapies across cancer types

المؤلفون: Anthony J. Chalmers, Jian-Hua Mao, Luis Palomero, Jade Moore, Amanda G. Paulovich, Daxian Luo, Qi Liu, Roderic Espín, Alvaro Aytes, Jeffrey R. Whiteaker, Mary Helen Barcellos-Hoff, Richard G. Ivey, George Iliakis, Ines Guix, John P. Murnane, Miquel Angel Pujana

المصدر: Sci Transl Med
Science translational medicine, vol 13, iss 580

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07b4b2527e9af80f5b93bc55939ade20
https://eprints.gla.ac.uk/226996/1/226996.pdf

2

NSD2 is a conserved driver of metastatic prostate cancer progression

المؤلفون: Cory Abate-Shen, Alvaro Aytes, Antonina Mitrofanova, Luis Palomero, Joanna Cyrta, Andrea Califano, Katia Ruggero, Mark A. Rubin, Michael M. Shen, Juan Arriaga, Arianna Giacobbe, Sonia Farran-Matas

المصدر: Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)

مصطلحات موضوعية: 0301 basic medicine, Male, Science, General Physics and Astronomy, Mice, Nude, General Biochemistry, Genetics and Molecular Biology, Article, Metastasis, 03 medical and health sciences, Prostate cancer, Mice, In vivo, Cell Line, Tumor, medicine, Gene silencing, Animals, Humans, Gene Silencing, Neoplasm Metastasis, RNA, Small Interfering, lcsh:Science, Regulation of gene expression, Multidisciplinary, business.industry, Cancer, Prostatic Neoplasms, General Chemistry, Histone-Lysine N-Methyltransferase, medicine.disease, 3. Good health, Gene expression profiling, Gene Expression Regulation, Neoplastic, Repressor Proteins, 030104 developmental biology, Genetically Engineered Mouse, Cancer research, Disease Progression, lcsh:Q, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9577e0bdb2a0c1e43ccd958cf3b4fb81
http://europepmc.org/articles/PMC6281610

Find this article in full text from ProQuest

3

A modular master regulator landscape controls cancer transcriptional identity

المؤلفون: Alessandro Vasciaveo, Andrea Califano, Brennan Chu, Somnath Tagore, Sunny J. Jones, Cory Abate-Shen, Federico M. Giorgi, Evan O. Paull, Siyuan Zheng, Prem S. Subramaniam, Mariano J. Alvarez, Eugene F Douglass, Alvaro Aytes, Roel G.W. Verhaak

المساهمون: Paull, Evan O, Aytes, Alvaro, Jones, Sunny J, Subramaniam, Prem S, Giorgi, Federico M, Douglass, Eugene F, Tagore, Somnath, Chu, Brennan, Vasciaveo, Alessandro, Zheng, Siyuan, Verhaak, Roel, Abate-Shen, Cory, Alvarez, Mariano J, Califano, Andrea

المصدر: Cell

مصطلحات موضوعية: Transcription, Genetic, Somatic cell, multiomic, Mice, Nude, cancer systems biology, Computational biology, Adenocarcinoma, Biology, Article, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, 0302 clinical medicine, integrative genomic, Cell Line, Tumor, Neoplasms, cancer genetic, Gene expression, medicine, Transcriptional regulation, Animals, Humans, network analysi, Gene Regulatory Networks, transcriptional regulation, genomic alteration, 030304 developmental biology, 0303 health sciences, Genome, Human, Reproducibility of Results, Cancer, medicine.disease, Phenotype, Gene Expression Regulation, Neoplastic, HEK293 Cells, Cancer systems biology, Colonic Neoplasms, Mutation, Cancer cell, Identity (object-oriented programming), pan-cancer analysi, 030217 neurology & neurosurgery

وصف الملف: ELETTRONICO

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8534fe71feb51967d2ac6a50bd71b778
https://doi.org/10.1016/j.cell.2020.11.045

4

Predicting Drug Response in Human Prostate Cancer from Preclinical Analysis of In Vivo Mouse Models

المؤلفون: Min Zou, Andrea Califano, Michael Michael M Shen, Antonina Mitrofanova, Cory Abate-Shen, Alvaro Aytes

المصدر: Cell Reports, Vol 12, Iss 12, Pp 2060-2071 (2015)

مصطلحات موضوعية: Male, Drug, endocrine system diseases, Carcinogenesis, Chromosomal Proteins, Non-Histone, media_common.quotation_subject, Drug Evaluation, Preclinical, Antineoplastic Agents, Mice, Transgenic, Pharmacology, medicine.disease_cause, Biomarkers, Pharmacological, Article, General Biochemistry, Genetics and Molecular Biology, Mice, Prostate cancer, Predictive Value of Tests, In vivo, Cell Line, Tumor, medicine, Animals, Humans, lcsh:QH301-705.5, media_common, biology, business.industry, Gene Expression Profiling, Forkhead Box Protein M1, Microfilament Proteins, CENPF, Prostatic Neoplasms, Drug Synergism, Forkhead Transcription Factors, medicine.disease, Survival Analysis, 3. Good health, Gene Expression Regulation, Neoplastic, Gene expression profiling, Disease Models, Animal, lcsh:Biology (General), Genetically Engineered Mouse, biology.protein, FOXM1, Cancer research, business, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d9b837ce70f16d62bba6c7d461373a5
http://www.sciencedirect.com/science/article/pii/S2211124715009481

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5

DNA-PKcs-Mediated Transcriptional Regulation Drives Prostate Cancer Progression and Metastasis

المصدر: Cancer cell, vol 28, iss 1
Goodwin, JF; Kothari, V; Drake, JM; Zhao, S; Dylgjeri, E; Dean, JL; et al.(2015). DNA-PKcs-Mediated Transcriptional Regulation Drives Prostate Cancer Progression and Metastasis. Cancer Cell, 28(1), 97-113. doi: 10.1016/j.ccell.2015.06.004. UCLA: Retrieved from: http://www.escholarship.org/uc/item/0470k9r9

مصطلحات موضوعية: Male, Cancer Research, DNA-Activated Protein Kinase, Metastasis, Androgen, Prostate cancer, Mice, Receptors, Transcriptional regulation, 2.1 Biological and endogenous factors, Gene Regulatory Networks, Aetiology, DNA-PKcs, Cancer, Regulation of gene expression, Tumor, Prostate Cancer, Nuclear Proteins, Gene Expression Regulation, Neoplastic, DNA-Binding Proteins, Oncology, Receptors, Androgen, biological phenomena, cell phenomena, and immunity, Urologic Diseases, DNA damage, DNA repair, Molecular Sequence Data, Oncology and Carcinogenesis, Biology, Article, Cell Line, Cell Line, Tumor, Breast Cancer, medicine, Genetics, Animals, Humans, Neoplasm Invasiveness, Oncology & Carcinogenesis, Neoplastic, Neurosciences, Prostatic Neoplasms, Cell Biology, medicine.disease, enzymes and coenzymes (carbohydrates), Gene Expression Regulation, Tumor progression, Cancer research, Neoplasm Transplantation