المؤلفون: Natália V. Bitencourt, Cecília G. Barbosa, Andre S. Godoy, Eduardo Maffud Cilli, Mariana Ortiz de Godoy, R.S. Fernandes, Eduardo P. de Souza, Norival A. Santos-Filho, Marjorie Caroline Liberato Cavalcanti Freire, G.D. Noske, A.M. Nakamura, Paulo R. S. Sanches, V.O. Gawriljuk, Lucio H. Freitas-Junior, Glaucius Oliva, Rafael Victorio Carvalho Guido, Carolina B. Moraes, Maria A. Juliano, Bianca M. Peres, Victor H. R. Nogueira

المساهمون: Universidade de São Paulo (USP), Universidade Estadual Paulista (UNESP), Universidade Federal de São Carlos (UFSCar)

المصدر: Molecules
Volume 26
Issue 16
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Molecules, Vol 26, Iss 4896, p 4896 (2021)

مصطلحات موضوعية: Protein Conformation, medicine.medical_treatment, Lysine, Pharmaceutical Science, Organic chemistry, Peptide, Antiviral Agents, Article, Analytical Chemistry, chemistry.chemical_compound, Protein structure, QD241-441, Crotalid Venoms, Papain, Drug Discovery, inhibitors, medicine, Protease Inhibitors, Physical and Theoretical Chemistry, IC50, chemistry.chemical_classification, Protease, Inhibitors, SARS-CoV-2, COVID-19, PROTEÍNAS, Papain-like protease, Molecular Docking Simulation, Enzyme, Biochemistry, Mechanism of action, chemistry, Chemistry (miscellaneous), peptides, Molecular Medicine, medicine.symptom, Peptides, Dimerization

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59c0d7a4020145c1c92343b4c7f9c510

المؤلفون: Flavio Di Pisa, Elisa Uliassi, Lucio H. Freitas-Junior, Maria Laura Bolognesi, Antonio Quotadamo, Maria Paola Costi, Claudia Danielli Pereira Bertolacini, Joachim Clos, Joanna Panecka-Hofman, Chiara Borsari, María Jesús Corral, G. Landi, Maria Kuzikov, Deepa Karunakaran, Pasquale Linciano, Wolfgang Müller, Birte Behrens, Kyriakos C. Prousis, Carolina B. Moraes, Lucia Dello Iacono, Markus Wolf, Oliver Keminer, Cecilia Pozzi, Rebecca C. Wade, Bruno dos Santos Pascoalino, José María Alunda, Stefania Ferrari, Martina Fenske, Alberto Venturelli, Sheraz Gul, Jeanette Reinshagen, Nuno Santarém, Matteo Santucci, Jennifer Leu, Stephen Wrigley, Ina Pöhner, Bethlehem Kebede, Theodora Calogeropoulou, Bernhard Ellinger, Stefano Mangani, Anabela Cordeiro-da-Silva, Gesa Witt

المساهمون: Carolina B. Moraes, Gesa Witt, Maria Kuzikov, Bernhard Ellinger, Theodora Calogeropoulou, Kyriakos C. Prousis, Stefano Mangani, Flavio Di Pisa, Giacomo Landi, Lucia Dello Iacono, Cecilia Pozzi, Lucio H. Freitas-Junior, Bruno dos Santos Pascoalino, Claudia P. Bertolacini, Birte Behrens, Oliver Keminer, Jennifer Leu, Markus Wolf, Jeanette Reinshagen, Anabela Cordeiro-da-Silva, Nuno Santarem, Alberto Venturelli, Stephen Wrigley, Deepa Karunakaran, Bethlehem Kebede, Ina Pöhner, Wolfgang Müller, Joanna Panecka-Hofman, Rebecca C. Wade, Martina Fenske, Joachim Clos, José María Alunda, María Jesús Corral, Elisa Uliassi, Maria Laura Bolognesi, Pasquale Linciano, Antonio Quotadamo, Stefania Ferrari, Matteo Santucci, Chiara Borsari, Maria Paola Costi, Sheraz Gul, Publica

المصدر: Slas Discovery

مصطلحات موضوعية: Chagas disease, cell-based assays, Antiparasitic, medicine.drug_class, cell-based assay, Computational biology, liquid handling, Trypanosoma brucei, 01 natural sciences, Biochemistry, Article, Analytical Chemistry, 03 medical and health sciences, chemistry.chemical_compound, Structure-Activity Relationship, Trypanosomiasis, anti-infective drugs, Drug Discovery, parasitic diseases, medicine, Humans, compound repositories, enzyme assays or enzyme kinetics, Biotechnology, Molecular Medicine, 030304 developmental biology, 0303 health sciences, Biological Products, Natural product, biology, Drug discovery, Leishmaniasis, biology.organism_classification, medicine.disease, Trypanocidal Agents, anti-infective drug, 0104 chemical sciences, 3. Good health, 010404 medicinal & biomolecular chemistry, chemistry, compound repositorie, Neglected tropical diseases, enzyme assays or enzyme kinetic

وصف الملف: ELETTRONICO

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd5b64ff9e20812ab96c4f3ad8331d20
https://hdl.handle.net/11380/1175165

المؤلفون: Thalita Camêlo da Silva Ferreira, Vanessa Fontana, Laura M. Alcântara, Carolina B. Moraes, Lucio H. Freitas-Junior, Eric Chatelain

المصدر: Molecules
Volume 25
Issue 11
Molecules, Vol 25, Iss 2551, p 2551 (2020)

مصطلحات موضوعية: THP-1 Cells, Phenotypic screening, 030231 tropical medicine, Antiprotozoal Agents, Drug Evaluation, Preclinical, Pharmaceutical Science, Biology, Article, Leishmania, Analytical Chemistry, lcsh:QD241-441, 03 medical and health sciences, Mice, 0302 clinical medicine, lcsh:Organic chemistry, Species Specificity, Leishmania species, Drug Discovery, Multi species, medicine, leishmaniasis drug discovery, Animals, Humans, Physical and Theoretical Chemistry, Protriptyline, Leishmaniasis, 030304 developmental biology, 0303 health sciences, Drug discovery, Organic Chemistry, phenotypic screening, medicine.disease, biology.organism_classification, Phenotype, Small molecule, Biochemistry, Maprotiline, Chemistry (miscellaneous), Molecular Medicine, Leishmaniasis, Visceral

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40958fcafa258e8a1a7f3c6e4e965aa3
http://europepmc.org/articles/PMC7321149

المؤلفون: Fábio P. Sellera, Douglas Ferreira Sales-Medina, Martha S. Ribeiro, Caetano P. Sabino, Edison Luiz Durigon, Lucio H. Freitas-Junior, Rafael Rahal Guaragna Machado

المصدر: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Photodiagnosis and Photodynamic Therapy

مصطلحات موضوعية: 0303 health sciences, 2019-20 coronavirus outbreak, Chemistry, viruses, Inactivation kinetics, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), fungi, 030303 biophysics, Kinetics, Biophysics, Dermatology, Photosensitizing Agent, Virology, Article, Virus, In vitro, RNA VIRAL, body regions, 030207 dermatology & venereal diseases, 03 medical and health sciences, 0302 clinical medicine, Oncology, Pharmacology (medical), skin and connective tissue diseases, Anti-Infective Agents

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aef4dde24829c09d99a1842a2a510e4b

المؤلفون: Nilmar Silvio Moretti, Laura M. Alcântara, Milena Botelho Pereira Soares, Sergio Schenkman, Rino Ragno, Carolina B. Moraes, Lucio H. Freitas-Junior, Nicola Mautone, Dante Rotili, Lorenzo Antonini, Manuela Sabatino, Antonello Mai, Caio Haddad Franco, Tanira Matutino Bastos

المصدر: International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 21, Iss 3659, p 3659 (2020)
Volume 21
Issue 10

مصطلحات موضوعية: 0301 basic medicine, deacetylation, sirtuins, Trypanosoma cruzi, sirtuin inhibitors, Pharmacology, 01 natural sciences, lcsh:Chemistry, lcsh:QH301-705.5, Spectroscopy, Phylogeny, media_common, chemistry.chemical_classification, biology, Group III Histone Deacetylases, Drug Synergism, General Medicine, Trypanocidal Agents, Recombinant Proteins, Computer Science Applications, Molecular Docking Simulation, Benznidazole, Nitroimidazoles, Sirtuin, medicine.drug, Chagas disease, Drug, media_common.quotation_subject, Catalysis, Article, Cell Line, Inorganic Chemistry, 03 medical and health sciences, Inhibitory Concentration 50, medicine, Animals, Chagas Disease, Physical and Theoretical Chemistry, Nifurtimox, Molecular Biology, 010405 organic chemistry, Organic Chemistry, Epithelial Cells, biology.organism_classification, medicine.disease, Macaca mulatta, 0104 chemical sciences, 030104 developmental biology, Enzyme, chemistry, lcsh:Biology (General), lcsh:QD1-999, biology.protein, NAD+ kinase

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be24b0eb23df1cb4b5d68310a7131e38
http://hdl.handle.net/11573/1401342

المؤلفون: Lucio H. Freitas-Junior, Eric Chatelain, Carolina B. Moraes, Caio Haddad Franco, Laura M. Alcântara

المصدر: Tropical Medicine and Infectious Disease; Volume 4; Issue 2; Pages: 82
Tropical Medicine and Infectious Disease
Tropical Medicine and Infectious Disease, Vol 4, Iss 2, p 82 (2019)

مصطلحات موضوعية: 0301 basic medicine, Chagas disease, Phenotypic screening, Trypanosoma cruzi, 030106 microbiology, Cell, chagas disease drug discovery, lcsh:Medicine, Biology, Article, 03 medical and health sciences, medicine, host cells, General Immunology and Microbiology, high content screening, Drug discovery, lcsh:R, phenotypic screening, Public Health, Environmental and Occupational Health, host-parasite interactions, medicine.disease, biology.organism_classification, Virology, 030104 developmental biology, Infectious Diseases, medicine.anatomical_structure, Cell culture, Benznidazole, High-content screening, medicine.drug

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f6a0e1644904b7564f4337743ad5a36

المؤلفون: Lavínia Maria Dal'Mas Romera, Caio Haddad Franco, Ana Claudia Torrecilhas, Ho Y.A. Au, Carolina B. Moraes, Hai Le, Bruno dos Santos Pascoalino, Tapan Bhattacharyya, Miriam A. Giardini, Rafael Pedro Madeira, Sergio Schenkman, Lucio H. Freitas-Junior, Eric Chatelain, David C. Warhurst, Michael A. Miles

المصدر: International Journal for Parasitology: Drugs and Drug Resistance
International Journal for Parasitology: Drugs and Drug Resistance, Vol 13, Iss, Pp 107-120 (2020)

مصطلحات موضوعية: 0301 basic medicine, Chagas disease, Trypanosoma cruzi, 030231 tropical medicine, Genes, Protozoan, Clone (cell biology), Drug resistance, CYP51, Biology, Ravuconazole, Article, Microbiology, lcsh:Infectious and parasitic diseases, Cell Line, 03 medical and health sciences, Sterol 14-Demethylase, 0302 clinical medicine, medicine, Animals, Pharmacology (medical), lcsh:RC109-216, Chagas Disease, Nifurtimox, Pharmacology, Triazoles, biology.organism_classification, medicine.disease, Trypanocidal Agents, Drug Resistance, Multiple, Multiple drug resistance, Thiazoles, 030104 developmental biology, Infectious Diseases, Benznidazole, 14-alpha Demethylase Inhibitors, Nitroimidazoles, Mutation, Parasitology, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07255fa405b4307071d0f14febe7a257
https://pubmed.ncbi.nlm.nih.gov/32688218

المؤلفون: Alberto A R, Mota, Jose R, Correa, Lorena P, de Andrade, José A F, Assumpção, Giovana A, de Souza Cintra, Lucio H, Freitas-Junior, Wender A, da Silva, Heibbe C B, de Oliveira, Brenno A D, Neto

المصدر: ACS Omega

مصطلحات موضوعية: Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::55b45f4d274f335e9f8adb420adcef5f
https://pubmed.ncbi.nlm.nih.gov/30023883

المؤلفون: Pasquale, Linciano, Alice, Dawson, Ina, Pöhner, David M, Costa, Monica S, Sá, Anabela, Cordeiro-da-Silva, Rosaria, Luciani, Sheraz, Gul, Gesa, Witt, Bernhard, Ellinger, Maria, Kuzikov, Philip, Gribbon, Jeanette, Reinshagen, Markus, Wolf, Birte, Behrens, Véronique, Hannaert, Paul A M, Michels, Erika, Nerini, Cecilia, Pozzi, Flavio, di Pisa, Giacomo, Landi, Nuno, Santarem, Stefania, Ferrari, Puneet, Saxena, Sandra, Lazzari, Giuseppe, Cannazza, Lucio H, Freitas-Junior, Carolina B, Moraes, Bruno S, Pascoalino, Laura M, Alcântara, Claudia P, Bertolacini, Vanessa, Fontana, Ulrike, Wittig, Wolfgang, Müller, Rebecca C, Wade, William N, Hunter, Stefano, Mangani, Luca, Costantino, Maria P, Costi

المصدر: ACS Omega

مصطلحات موضوعية: Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::e3856ae3b67f1ead30b96bc69ec6ec56
https://pubmed.ncbi.nlm.nih.gov/28983525

المؤلفون: Carolina B. Moraes, Scott G. Franzblau, Eugene N. Muratov, Laura M. Alcântara, Cleber C. Melo-Filho, Bruno J. Neves, Carolina Horta Andrade, Rui Ma, Marcelo N. Gomes, Lucio H. Freitas-Junior

مصطلحات موضوعية: 0301 basic medicine, Chalcone, Proteases, Databases, Factual, Nitrofurans, Clinical Biochemistry, Antiprotozoal Agents, Pharmaceutical Science, Pharmacology, Cysteine Proteinase Inhibitors, Biochemistry, Article, Piperazines, 03 medical and health sciences, chemistry.chemical_compound, Structure-Activity Relationship, Chalcones, Piperidines, Amphotericin B, Chlorocebus aethiops, Drug Discovery, medicine, Animals, Humans, Computer Simulation, Leishmania infantum, Amastigote, Cytotoxicity, Molecular Biology, Vero Cells, biology, Organic Chemistry, Leishmaniasis, biology.organism_classification, medicine.disease, Molecular Docking Simulation, 030104 developmental biology, chemistry, Docking (molecular), Vero cell, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::743f729e13c5ab3d360c7237c86e9d18
https://europepmc.org/articles/PMC6020026/