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المؤلفون: Jasna Chalangal, Sanoara Mazid, Teresa A. Milner, Kyle A. Windisch
المصدر: Pharmacol Biochem Behav
مصطلحات موضوعية: Male, Enkephalin, Clinical Biochemistry, Conditioning, Classical, Receptors, Opioid, mu, Toxicology, Biochemistry, κ-opioid receptor, Hippocampus, Article, Behavioral Neuroscience, Receptors, Opioid, delta, Medicine, Animals, Learning, Chronic stress, Opioid peptide, Biological Psychiatry, Pharmacology, Neurons, Sex Characteristics, business.industry, Receptors, Opioid, kappa, Opioid-Related Disorders, Associative learning, Rats, Analgesics, Opioid, Microscopy, Electron, Opioid, Opioid Peptides, Receptors, Estrogen, Receptors, Opioid, Female, μ-opioid receptor, business, Neuroscience, Oxycodone, Stress, Psychological, medicine.drug
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المؤلفون: Anh D. Lê, Alexandrine L. Martel, Leila Mousavifar, Jordan D. Lewicky, Hoang-Thanh Le, Thi M.-D. Nguyen, René Roy, Douglas Funk, Nya L. Fraleigh, Peter W. Schiller
المصدر: International Journal of Molecular Sciences
Volume 22
Issue 15
International Journal of Molecular Sciences, Vol 22, Iss 7996, p 7996 (2021)مصطلحات موضوعية: kappa opioid receptor antagonist, QH301-705.5, dynantin, Dynorphin, Pharmacology, Blood–brain barrier, blood–brain barrier, Dynorphins, κ-opioid receptor, Article, Catalysis, Inorganic Chemistry, 03 medical and health sciences, 0302 clinical medicine, In vivo, glycoliposome, Humans, Medicine, Distribution (pharmacology), Biology (General), Physical and Theoretical Chemistry, QD1-999, Molecular Biology, Spectroscopy, 030304 developmental biology, 0303 health sciences, business.industry, Receptors, Opioid, kappa, Organic Chemistry, Antagonist, targeted delivery, General Medicine, Corpus Striatum, peptide, 3. Good health, Computer Science Applications, Chemistry, medicine.anatomical_structure, Targeted drug delivery, CNS therapeutic, Liposomes, Nasal administration, addiction, dopamine, Peptides, business, 030217 neurology & neurosurgery, neurotransmitter
وصف الملف: application/pdf
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المؤلفون: Christian W. Gruber, Michael Freissmuth, Edin Muratspahić, Fabiola Susanna Emser, Shahrooz Nasrollahi-Shirazi, Nataša Tomašević, Jasmin Gattringer
المصدر: Journal of Natural Products
مصطلحات موضوعية: Agonist, medicine.drug_class, Allosteric regulation, Pharmaceutical Science, Cyclotides, Dynorphin, Pharmacology, Ligands, Article, Analytical Chemistry, Opioid receptor, Drug Discovery, medicine, Humans, G protein-coupled receptor, Chemistry, Cephaelis, Plant Extracts, Receptors, Opioid, kappa, Organic Chemistry, Cystine knot, Cyclotide, HEK293 Cells, Complementary and alternative medicine, Molecular Medicine, Signal Transduction
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المؤلفون: Ettore Novellino, Sako Mirzaie, Valeria Iobbi, Stefano Pieretti, Alice Della Valle, Paola Minosi, Giuseppe Scioli, Adriano Mollica, Azzurra Stefanucci
المصدر: Molecules
Molecules, Vol 26, Iss 4767, p 4767 (2021)
Volume 26
Issue 16مصطلحات موضوعية: Drug, binding, Computer science, Protein Conformation, In silico, media_common.quotation_subject, Pharmaceutical Science, Organic chemistry, Computational biology, Tripeptide, Molecular Dynamics Simulation, Ligands, Article, Analytical Chemistry, chemistry.chemical_compound, QD241-441, In vivo, Drug Discovery, Peptide synthesis, Antinociceptive effect, Binding, K-opioid receptor, Molecular modelling, Peptides, Computer Simulation, Physical and Theoretical Chemistry, media_common, Virtual screening, Drug discovery, Receptors, Opioid, kappa, molecular modelling, k-opioid receptor, chemistry, Chemistry (miscellaneous), Drug Design, peptides, Molecular Medicine, Identification (biology), Oligopeptides, antinociceptive effect
وصف الملف: application/pdf
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المؤلفون: Heather A. Emmons, Sarah A. Hutcherson, Steve C. Fordahl, Nari S. Beatty, Conner W. Wallace, Madison C. Loudermilt
المصدر: Nutrients
Volume 13
Issue 7
Nutrients, Vol 13, Iss 2341, p 2341 (2021)مصطلحات موضوعية: Dopamine, Stimulation, Synaptic Transmission, Nucleus Accumbens, Mice, 0302 clinical medicine, elevated plus-maze, Weight loss, Opioid receptor, Medicine, TX341-641, Diet, Fat-Restricted, 0303 health sciences, Nutrition and Dietetics, digestive, oral, and skin physiology, anxiety-like behavior, dopamine neurotransmission, medicine.symptom, medicine.drug, medicine.medical_specialty, Elevated plus maze, κ-opioid receptors, diet-induced obesity, medicine.drug_class, Fast-scan cyclic voltammetry, Nucleus accumbens, Diet, High-Fat, Article, 03 medical and health sciences, fast-scan cyclic voltammetry, Internal medicine, Animals, Obesity, nucleus accumbens core, 030304 developmental biology, high-fat diet replacement, business.industry, Nutrition. Foods and food supply, Receptors, Opioid, kappa, medicine.disease, Dietary Fats, Mice, Inbred C57BL, Disease Models, Animal, Endocrinology, novelty-induced hypophagia, business, 030217 neurology & neurosurgery, Food Science
وصف الملف: application/pdf
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المؤلفون: David J. Craik, Spyridon Sideromenos, Joel Castro, Stuart M. Brierley, Christian W. Gruber, Edin Muratspahić, Leopold Duerrauer, Nataša Tomašević, Seid Hadžić, Richard J. Clark, Gudrun Schober, Johannes Koehbach
المصدر: Journal of Medicinal Chemistry
مصطلحات موضوعية: Male, medicine.drug_class, Analgesic, Peptide, Pharmacology, 01 natural sciences, Peptides, Cyclic, Article, 03 medical and health sciences, chemistry.chemical_compound, Mice, Structure-Activity Relationship, Opioid receptor, Drug Discovery, medicine, Animals, Humans, Receptor, Cells, Cultured, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, Analgesics, Dose-Response Relationship, Drug, Molecular Structure, Plant Extracts, Receptors, Opioid, kappa, Dynorphin A, Visceral pain, Cyclic peptide, 3. Good health, 0104 chemical sciences, Abdominal Pain, Mice, Inbred C57BL, 010404 medicinal & biomolecular chemistry, HEK293 Cells, chemistry, Opioid, Drug Design, Chronic Disease, Seeds, Molecular Medicine, Helianthus, medicine.symptom, medicine.drug
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37
المؤلفون: Harrison M, Fontaine, Phillip R, Silva, Carlie, Neiswanger, Rachelle, Tran, Antony D, Abraham, Benjamin B, Land, John F, Neumaier, Charles, Chavkin
المصدر: Neuropsychopharmacology
مصطلحات موضوعية: Male, Mice, Inbred C57BL, Mice, Serotonin, Cocaine, Receptors, Opioid, kappa, Animals, Nucleus Accumbens, Article
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38
المؤلفون: Antony D. Abraham, Karan Mahe, Brenden A. Wong, Selena S. Schattauer, Sanne M. Casello, Benjamin B. Land, Charles Chavkin, Lin Tian, Grace O. Mizuno
المصدر: Neuropsychopharmacology
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, vol 46, iss 13مصطلحات موضوعية: Male, Prefrontal Cortex, Dynorphin, Opioid, Inbred C57BL, κ-opioid receptor, Medical and Health Sciences, Dynorphins, Naltrexone, Article, Substance Misuse, Mice, Cognition, Postsynaptic potential, Receptors, Behavioral and Social Science, medicine, Animals, Prefrontal cortex, kappa, Pharmacology, Psychiatry, Analgesics, Neocortex, business.industry, Receptors, Opioid, kappa, Psychology and Cognitive Sciences, Antagonist, Neurosciences, Brain Disorders, Analgesics, Opioid, Mice, Inbred C57BL, Psychiatry and Mental health, medicine.anatomical_structure, Good Health and Well Being, nervous system, business, Norbinaltorphimine, Neuroscience, medicine.drug
وصف الملف: application/pdf
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39
المؤلفون: Yan Zhou, Yupu Liang
المصدر: Neurosci Lett
مصطلحات موضوعية: 0301 basic medicine, Agonist, Male, G-Protein-Coupled Receptor Kinase 3, G-Protein-Coupled Receptor Kinase 2, medicine.drug_class, Pyridines, Pharmacology, Nucleus accumbens, κ-opioid receptor, Nucleus Accumbens, Article, 03 medical and health sciences, Mice, 0302 clinical medicine, medicine, Animals, Humans, Spiro Compounds, Receptor, G protein-coupled receptor kinase, biology, Ethanol, Chemistry, General Neuroscience, Beta adrenergic receptor kinase, Receptors, Opioid, kappa, Drug Synergism, Triazoles, Alcoholism, Disease Models, Animal, 030104 developmental biology, Morphinans, Benzamides, biology.protein, Drug Therapy, Combination, μ-opioid receptor, 030217 neurology & neurosurgery, Nalfurafine, medicine.drug
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40
المصدر: Pharmacol Biochem Behav
مصطلحات موضوعية: Pharmacology, Alcohol Drinking, Ethanol, Receptors, Opioid, kappa, Clinical Biochemistry, Toxicology, beta-Arrestin 2, Biochemistry, Article, Analgesics, Opioid, Behavioral Neuroscience, Animals, beta-Arrestins, Biological Psychiatry