نتائج البحث - "Receptors, Opioid, kappa"

1

Dynorphin/Kappa Opioid Receptor Activity Within the Extended Amygdala Contributes to Stress-Enhanced Alcohol Drinking in Mice

المؤلفون: Harold L. Haun, Christina L. Lebonville, Matthew G. Solomon, William C. Griffin, Marcelo F. Lopez, Howard C. Becker

المصدر: Biol Psychiatry

مصطلحات موضوعية: Alcohol Drinking, Ethanol, Receptors, Opioid, kappa, Central Amygdaloid Nucleus, Comorbidity, Dynorphins, Article, Naltrexone, Alcoholism, Disease Models, Animal, Mice, Animals, RNA, Messenger, Biological Psychiatry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43c9e7021eb41b695d4161cf8b8a7738
https://doi.org/10.1016/j.biopsych.2022.01.002

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2

Nalfurafine, a G-Protein-Biased KOR (Kappa Opioid Receptor) Agonist, Enhances the Diuretic Response and Limits Electrolyte Losses to Standard-of-Care Diuretics

المؤلفون: Juan Gao, Jane Sutphen, Jacob K. Meariman, Daniel R. Kapusta

المصدر: Hypertension

مصطلحات موضوعية: Male, Mean arterial pressure, medicine.medical_treatment, Diuresis, Pharmacology, Kidney, Article, Excretion, Rats, Sprague-Dawley, Hydrochlorothiazide, Furosemide, Internal Medicine, medicine, Animals, Spiro Compounds, Diuretics, business.industry, Receptors, Opioid, kappa, Amiloride, Rats, Analgesics, Opioid, Morphinans, Diuretic, business, Nalfurafine, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::583a30651455d09e91b9ddad6bd04ef6
https://pubmed.ncbi.nlm.nih.gov/34852633

3

Dichotomous Regulation of Striatal Plasticity by Dynorphin

المؤلفون: Renzhi Yang, Rupa R. Lalchandani Tuan, Fuu-Jiun Hwang, Daniel W. Bloodgood, Dong Kong, Jun B. Ding

المصدر: Mol Psychiatry
Molecular psychiatry, vol 28, iss 1

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbd7a25614a0e1b3f6085a0b55cd83c2
https://europepmc.org/articles/PMC10188294/

4

The kappa-opioid receptor agonist, triazole 1.1, reduces oxycodone self-administration and enhances oxycodone-induced thermal antinociception in male rats

المؤلفون: Hayley M. Schrock, Thomas E. Prisinzano, Kevin B. Freeman, Kenneth J. Sufka, Bruce E. Blough, C. Austin Zamarripa, Tanya Pareek

المصدر: Psychopharmacology (Berl)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3ae9f35c0523136028369645ad93dd4
https://doi.org/10.1007/s00213-021-05965-x

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5

Effect of difelikefalin, a selective kappa opioid receptor agonist, on respiratory depression: A randomized, double‐blind, placebo‐controlled trial

المؤلفون: Catherine Munera, Eugene R. Viscusi, Beatrice Setnik, Joseph W. Stauffer, Sukirti N. Bagal, Marc C. Torjman

المصدر: Clinical and Translational Science
Clinical and Translational Science, Vol 14, Iss 5, Pp 1886-1893 (2021)

مصطلحات موضوعية: Adult, Male, Respiratory rate, Adolescent, Placebo-controlled study, RM1-950, Placebo, General Biochemistry, Genetics and Molecular Biology, Article, Placebos, chemistry.chemical_compound, Young Adult, Double-Blind Method, Piperidines, Respiratory Rate, Medicine, Humans, General Pharmacology, Toxicology and Pharmaceutics, Respiratory system, Adverse effect, Cross-Over Studies, business.industry, General Neuroscience, Research, Incidence, Pruritus, Receptors, Opioid, kappa, General Medicine, Hypoesthesia, Articles, Carbon Dioxide, Middle Aged, Crossover study, Healthy Volunteers, chemistry, Oxygen Saturation, Anesthesia, Female, Therapeutics. Pharmacology, Public aspects of medicine, RA1-1270, medicine.symptom, business, Respiratory Insufficiency, Difelikefalin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c12957dcc80984d4a9573ad40c93c93a
http://europepmc.org/articles/PMC8504812

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6

The G-protein biased kappa opioid agonists, triazole 1.1 and nalfurafine, produce non-uniform behavioral effects in male rhesus monkeys

المؤلفون: Sally L. Huskinson, Donna M. Platt, C. Austin Zamarripa, Kristen Dunaway, Morgan Brasfield, Thomas E. Prisinzano, Bruce E. Blough, Kevin B. Freeman

المصدر: Pharmacol Biochem Behav

مصطلحات موضوعية: Pharmacology, Male, Receptors, Opioid, kappa, Clinical Biochemistry, Triazoles, Toxicology, Biochemistry, Macaca mulatta, Article, Analgesics, Opioid, Behavioral Neuroscience, Morphinans, GTP-Binding Proteins, Animals, Hypnotics and Sedatives, Spiro Compounds, Biological Psychiatry, Oxycodone

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1714d7150d68198121a58e626c4ead9
https://europepmc.org/articles/PMC9629661/

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Topical administration of the kappa opioid receptor agonist nalfurafine suppresses corneal neovascularization and inflammation

المؤلفون: Akira Murakami, Ken Nagino, Kenta Fujio, Jaemyoung Sung, Ai Yanagawa, Jun Zhu, Mizu Kuwahara, Yasutsugu Akasaki, Yuichi Okumura, Takenori Inomata, Tsuyoshi Saitoh, Atsuko Eguchi, Maria Miura, Hurramhon Shokirova, Kunihiko Hirosawa, Hiroshi Nagase, Keiichi Fujimoto

المصدر: Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Scientific Reports

مصطلحات موضوعية: Male, 0301 basic medicine, Agonist, genetic structures, Neutrophils, Corneal diseases, medicine.drug_class, Administration, Topical, Corneal Stroma, Science, Gene Expression, Inflammation, Pharmacology, κ-opioid receptor, Article, Mice, 03 medical and health sciences, 0302 clinical medicine, Cornea, Animals, Medicine, Corneal Neovascularization, Spiro Compounds, RNA, Messenger, Mice, Inbred BALB C, Multidisciplinary, business.industry, Macrophages, Receptors, Opioid, kappa, Corneal Edema, medicine.disease, eye diseases, Lymphangiogenesis, 030104 developmental biology, medicine.anatomical_structure, Morphinans, Corneal neovascularization, 030221 ophthalmology & optometry, Immunohistochemistry, sense organs, medicine.symptom, business, Nalfurafine, medicine.drug

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b0d8e2156dac901c419ae00e29052f6
https://doaj.org/article/3ae6a01079114237a7e64390f3ffeccb

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8

Dysregulated kappa-opioid receptors in the medial prefrontal cortex contribute to working memory deficits in alcohol dependence

المؤلفون: Gengze Wei, Sunil Sirohi, Brendan M. Walker

المصدر: Addict Biol

مصطلحات موضوعية: Pharmacology, Male, Psychiatry and Mental health, Alcoholism, Memory Disorders, Memory, Short-Term, Receptors, Opioid, kappa, Medicine (miscellaneous), Animals, Prefrontal Cortex, Rats, Wistar, Article, Rats

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cd379df057adaef2179b2cc8cf8ed39
https://europepmc.org/articles/PMC8829053/

9

6,5‐Fused Ring, C2‐Salvinorin Ester, Dual Kappa and Mu Opioid Receptor Agonists as Analgesics Devoid of Anxiogenic Effects**

المؤلفون: Nicholas S. Akins, Nisha Mishra, Hannah M. Harris, Narendar Dudhipala, Seong Jong Kim, Adam W. Keasling, Soumyajit Majumdar, Jordan K. Zjawiony, Jason J. Paris, Nicole M. Ashpole, Hoang V. Le

المصدر: ChemMedChem

مصطلحات موضوعية: Male, Pharmacology, Analgesics, Receptors, Opioid, kappa, Organic Chemistry, Receptors, Opioid, mu, Esters, Biochemistry, Article, Diterpenes, Clerodane, Analgesics, Opioid, Mice, Drug Discovery, Animals, Molecular Medicine, General Pharmacology, Toxicology and Pharmaceutics

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c432589cef9b3e037bc7943fe450b939
https://doi.org/10.1002/cmdc.202100684

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10

Potential for Kappa-Opioid Receptor Agonists to Engineer Nonaddictive Analgesics: A Narrative Review

المؤلفون: Joshua D Gross, Allison N White, David P. Siderovski, Shane W Kaski

المصدر: Anesth Analg

مصطلحات موضوعية: Nociception, Agonist, medicine.drug_class, Narcotic Antagonists, media_common.quotation_subject, Receptors, Opioid, mu, Bioinformatics, κ-opioid receptor, Article, Nociceptive Pain, Heroin, Structure-Activity Relationship, 03 medical and health sciences, 0302 clinical medicine, 030202 anesthesiology, Intervention (counseling), mental disorders, medicine, Animals, Humans, media_common, Molecular Structure, business.industry, Receptors, Opioid, kappa, Addiction, Opioid use disorder, Opioid overdose, Opioid-Related Disorders, medicine.disease, Anesthesiology and Pain Medicine, Drug Design, business, RGS Proteins, 030217 neurology & neurosurgery, Nalfurafine, Signal Transduction, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dfffafc723977b8649f3fd4b565e6a8
https://doi.org/10.1213/ane.0000000000005309

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