المؤلفون: Gisterå A; Cardiovascular Medicine, Department of Medicine Solna, Karolinska Institutet and Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden (A.G., D.F.J.K., S.G.M., G.K.H.)., Ketelhuth DFJ; Cardiovascular Medicine, Department of Medicine Solna, Karolinska Institutet and Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden (A.G., D.F.J.K., S.G.M., G.K.H.).; Department of Cardiovascular and Renal Research, Institute for Molecular Medicine, University of Southern Denmark (SDU), Odense, Denmark (D.F.J.K)., Malin SG; Cardiovascular Medicine, Department of Medicine Solna, Karolinska Institutet and Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden (A.G., D.F.J.K., S.G.M., G.K.H.)., Hansson GK; Cardiovascular Medicine, Department of Medicine Solna, Karolinska Institutet and Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden (A.G., D.F.J.K., S.G.M., G.K.H.).

المصدر: Circulation research [Circ Res] 2022 Jun 10; Vol. 130 (12), pp. 1869-1887. Date of Electronic Publication: 2022 Jun 09.

نوع المنشور: Journal Article; Review; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0047103 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1524-4571 (Electronic) Linking ISSN: 00097330 NLM ISO Abbreviation: Circ Res Subsets: MEDLINE

مواضيع طبية MeSH: Atherosclerosis* , Cardiovascular Diseases*, Animals ; Cholesterol ; Inflammation ; Models, Animal

المؤلفون: Rykaczewska U; Division of Vascular Surgery, Department of Molecular Medicine and Surgery (U.R., M.L., M.K., K.L., K.W., K.C., J.R., A.R., U.H., L.M.), Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden., Zhao Q; Division of Cardiovascular Medicine, Cardiovascular Institute (Q.Z., P.S.-G.), Stanford University School of Medicine, CA., Saliba-Gustafsson P; Cardiovascular Medicine Unit, Department of Medicine, Center for Molecular Medicine (P.S.-G., O.B., G.K.H., P.E., E.E.), Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden.; Division of Cardiovascular Medicine, Cardiovascular Institute (Q.Z., P.S.-G.), Stanford University School of Medicine, CA., Lengquist M; Division of Vascular Surgery, Department of Molecular Medicine and Surgery (U.R., M.L., M.K., K.L., K.W., K.C., J.R., A.R., U.H., L.M.), Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden., Kronqvist M; Division of Vascular Surgery, Department of Molecular Medicine and Surgery (U.R., M.L., M.K., K.L., K.W., K.C., J.R., A.R., U.H., L.M.), Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden., Bergman O; Cardiovascular Medicine Unit, Department of Medicine, Center for Molecular Medicine (P.S.-G., O.B., G.K.H., P.E., E.E.), Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden., Huang Z; Department of Biosciences and Nutrition (Z.H., E.T.), Karolinska Institutet, Stockholm, Sweden., Lund K; Division of Vascular Surgery, Department of Molecular Medicine and Surgery (U.R., M.L., M.K., K.L., K.W., K.C., J.R., A.R., U.H., L.M.), Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden., Waden K; Division of Vascular Surgery, Department of Molecular Medicine and Surgery (U.R., M.L., M.K., K.L., K.W., K.C., J.R., A.R., U.H., L.M.), Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden., Pons Vila Z; Clinical Chemistry and Blood Coagulation, Department of Molecular Medicine and Surgery (Z.P.V.), Karolinska Institutet, Stockholm, Sweden., Caidahl K; Division of Vascular Surgery, Department of Molecular Medicine and Surgery (U.R., M.L., M.K., K.L., K.W., K.C., J.R., A.R., U.H., L.M.), Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden.; Department of Clinical Physiology, Sahlgrenska University Hospital and Molecular and Clinical Medicine, University of Gothenburg, Sweden (K.C.)., Skogsberg J; Department of Medical Biochemistry and Biophysics (J.S.), Karolinska Institutet, Stockholm, Sweden., Vukojevic V; Department of Clinical Neuroscience, Center for Molecular Medicine (V.V.), Karolinska Institutet, Stockholm, Sweden., Lindeman JHN; Department of Vascular Surgery, Leiden University Medical Center, the Netherlands (J.H.N.L.)., Roy J; Division of Vascular Surgery, Department of Molecular Medicine and Surgery (U.R., M.L., M.K., K.L., K.W., K.C., J.R., A.R., U.H., L.M.), Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden., Hansson GK; Cardiovascular Medicine Unit, Department of Medicine, Center for Molecular Medicine (P.S.-G., O.B., G.K.H., P.E., E.E.), Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden., Treuter E; Department of Biosciences and Nutrition (Z.H., E.T.), Karolinska Institutet, Stockholm, Sweden., Leeper NJ; Department of Surgery (N.J.L.), Stanford University School of Medicine, CA.; Department of Medicine (N.J.L.), Stanford University School of Medicine, CA., Eriksson P; Cardiovascular Medicine Unit, Department of Medicine, Center for Molecular Medicine (P.S.-G., O.B., G.K.H., P.E., E.E.), Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden., Ehrenborg E; Cardiovascular Medicine Unit, Department of Medicine, Center for Molecular Medicine (P.S.-G., O.B., G.K.H., P.E., E.E.), Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden., Razuvaev A; Division of Vascular Surgery, Department of Molecular Medicine and Surgery (U.R., M.L., M.K., K.L., K.W., K.C., J.R., A.R., U.H., L.M.), Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden., Hedin U; Division of Vascular Surgery, Department of Molecular Medicine and Surgery (U.R., M.L., M.K., K.L., K.W., K.C., J.R., A.R., U.H., L.M.), Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden., Matic L; Division of Vascular Surgery, Department of Molecular Medicine and Surgery (U.R., M.L., M.K., K.L., K.W., K.C., J.R., A.R., U.H., L.M.), Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden.

المصدر: Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2022 May; Vol. 42 (5), pp. 659-676. Date of Electronic Publication: 2022 Mar 24.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 9505803 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1524-4636 (Electronic) Linking ISSN: 10795642 NLM ISO Abbreviation: Arterioscler Thromb Vasc Biol Subsets: MEDLINE

مواضيع طبية MeSH: Atherosclerosis*/diagnostic imaging , Atherosclerosis*/genetics , Atherosclerosis*/metabolism , Plaque, Atherosclerotic*/pathology, Repressor Proteins/*metabolism, Animals ; Cell Transdifferentiation ; Humans ; Lipids ; Mice ; Myocytes, Smooth Muscle/metabolism ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Repressor Proteins/genetics ; Transcriptome ; Tumor Suppressor Proteins/genetics ; Ultrasonography

المؤلفون: Arnardottir H; Division of Cardiovascular Medicine, Center for Molecular Medicine, Department of Medicine Solna, Karolinska Institute, and., Thul S; Division of Cardiovascular Medicine, Center for Molecular Medicine, Department of Medicine Solna, Karolinska Institute, and., Pawelzik SC; Division of Cardiovascular Medicine, Center for Molecular Medicine, Department of Medicine Solna, Karolinska Institute, and.; Theme Heart and Vessels, Division of Valvular and Coronary Disease, Karolinska University Hospital, Stockholm, Sweden., Karadimou G; Division of Cardiovascular Medicine, Center for Molecular Medicine, Department of Medicine Solna, Karolinska Institute, and., Artiach G; Division of Cardiovascular Medicine, Center for Molecular Medicine, Department of Medicine Solna, Karolinska Institute, and., Gallina AL; Division of Cardiovascular Medicine, Center for Molecular Medicine, Department of Medicine Solna, Karolinska Institute, and., Mysdotter V; Division of Cardiovascular Medicine, Center for Molecular Medicine, Department of Medicine Solna, Karolinska Institute, and., Carracedo M; Division of Cardiovascular Medicine, Center for Molecular Medicine, Department of Medicine Solna, Karolinska Institute, and., Tarnawski L; Division of Cardiovascular Medicine, Center for Molecular Medicine, Department of Medicine Solna, Karolinska Institute, and., Caravaca AS; Division of Cardiovascular Medicine, Center for Molecular Medicine, Department of Medicine Solna, Karolinska Institute, and., Baumgartner R; Division of Cardiovascular Medicine, Center for Molecular Medicine, Department of Medicine Solna, Karolinska Institute, and., Ketelhuth DF; Division of Cardiovascular Medicine, Center for Molecular Medicine, Department of Medicine Solna, Karolinska Institute, and.; Department of Cardiovascular and Renal Research, Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark., Olofsson PS; Division of Cardiovascular Medicine, Center for Molecular Medicine, Department of Medicine Solna, Karolinska Institute, and., Paulsson-Berne G; Division of Cardiovascular Medicine, Center for Molecular Medicine, Department of Medicine Solna, Karolinska Institute, and., Hansson GK; Division of Cardiovascular Medicine, Center for Molecular Medicine, Department of Medicine Solna, Karolinska Institute, and., Bäck M; Division of Cardiovascular Medicine, Center for Molecular Medicine, Department of Medicine Solna, Karolinska Institute, and.; Theme Heart and Vessels, Division of Valvular and Coronary Disease, Karolinska University Hospital, Stockholm, Sweden.

المصدر: The Journal of clinical investigation [J Clin Invest] 2021 Dec 15; Vol. 131 (24).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: Print Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE

مواضيع طبية MeSH: Atherosclerosis*/genetics , Atherosclerosis*/metabolism , Atherosclerosis*/prevention & control, Macrophages/*metabolism , Signal Transduction/*genetics, Animals ; Disease Models, Animal ; Docosahexaenoic Acids/genetics ; Docosahexaenoic Acids/metabolism ; Female ; Humans ; Inflammation/genetics ; Inflammation/metabolism ; Inflammation/prevention & control ; Male ; Mice ; Mice, Knockout, ApoE ; Peritonitis/chemically induced ; Peritonitis/genetics ; Peritonitis/metabolism ; Phagocytosis/genetics ; Receptors, G-Protein-Coupled/genetics ; Receptors, G-Protein-Coupled/metabolism

المؤلفون: Berg M; Cardiovascular Medicine Unit, Department of Medicine, Center for Molecular Medicine, Karolinska Institute, Karolinska University Hospital, SE-17176 Stockholm, Sweden., Polyzos KA; Cardiovascular Medicine Unit, Department of Medicine, Center for Molecular Medicine, Karolinska Institute, Karolinska University Hospital, SE-17176 Stockholm, Sweden., Agardh H; Cardiovascular Medicine Unit, Department of Medicine, Center for Molecular Medicine, Karolinska Institute, Karolinska University Hospital, SE-17176 Stockholm, Sweden., Baumgartner R; Cardiovascular Medicine Unit, Department of Medicine, Center for Molecular Medicine, Karolinska Institute, Karolinska University Hospital, SE-17176 Stockholm, Sweden., Forteza MJ; Cardiovascular Medicine Unit, Department of Medicine, Center for Molecular Medicine, Karolinska Institute, Karolinska University Hospital, SE-17176 Stockholm, Sweden., Kareinen I; Cardiovascular Medicine Unit, Department of Medicine, Center for Molecular Medicine, Karolinska Institute, Karolinska University Hospital, SE-17176 Stockholm, Sweden., Gisterå A; Cardiovascular Medicine Unit, Department of Medicine, Center for Molecular Medicine, Karolinska Institute, Karolinska University Hospital, SE-17176 Stockholm, Sweden., Bottcher G; Pathology, Drug Safety and Metabolism, IMED Biotech Unit, AstraZeneca, SE-43189 Gothenburg, Sweden., Hurt-Camejo E; Cardiovascular, Renal and Metabolic Diseases, Innovative Medicines and Early Development Biotech Unit, AstraZeneca, SE-43183 Gothenburg, Sweden., Hansson GK; Cardiovascular Medicine Unit, Department of Medicine, Center for Molecular Medicine, Karolinska Institute, Karolinska University Hospital, SE-17176 Stockholm, Sweden., Ketelhuth DFJ; Cardiovascular Medicine Unit, Department of Medicine, Center for Molecular Medicine, Karolinska Institute, Karolinska University Hospital, SE-17176 Stockholm, Sweden.

المصدر: Cardiovascular research [Cardiovasc Res] 2020 Oct 01; Vol. 116 (12), pp. 1948-1957.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Oxford Journals Country of Publication: England NLM ID: 0077427 Publication Model: Print Cited Medium: Internet ISSN: 1755-3245 (Electronic) Linking ISSN: 00086363 NLM ISO Abbreviation: Cardiovasc Res Subsets: MEDLINE

مواضيع طبية MeSH: 3-Hydroxyanthranilic Acid/*metabolism , Atherosclerosis/*metabolism , Inflammasomes/*metabolism , Lipoproteins/*blood , Liver/*metabolism , Macrophages/*metabolism , Receptors, LDL/*deficiency , Sterol Regulatory Element Binding Protein 2/*metabolism, 3-Hydroxyanthranilate 3,4-Dioxygenase/antagonists & inhibitors ; 3-Hydroxyanthranilate 3,4-Dioxygenase/metabolism ; 3-Hydroxyanthranilic Acid/analogs & derivatives ; 3-Hydroxyanthranilic Acid/pharmacology ; Animals ; Atherosclerosis/genetics ; Atherosclerosis/pathology ; Atherosclerosis/prevention & control ; Disease Models, Animal ; Enzyme Inhibitors/pharmacology ; Hep G2 Cells ; Humans ; Interleukin-1beta/metabolism ; Liver/drug effects ; Macrophages/drug effects ; Macrophages/pathology ; Mice, Inbred C57BL ; Mice, Knockout ; Plaque, Atherosclerotic ; Receptors, LDL/genetics ; Signal Transduction ; Sterol Regulatory Element Binding Protein 2/genetics

المؤلفون: Karadimou G; Laboratory of Immunobiology, Cardiovascular Medicine Unit, Department of Medicine, Center for Molecular Medicine, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden., Gisterå A; Laboratory of Immunobiology, Cardiovascular Medicine Unit, Department of Medicine, Center for Molecular Medicine, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden., Gallina AL; Laboratory of Immunobiology, Cardiovascular Medicine Unit, Department of Medicine, Center for Molecular Medicine, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden., Caravaca AS; Laboratory of Immunobiology, Cardiovascular Medicine Unit, Department of Medicine, Center for Molecular Medicine, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden., Centa M; Laboratory of Immunobiology, Cardiovascular Medicine Unit, Department of Medicine, Center for Molecular Medicine, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden., Salagianni M; Clinical, Experimental Surgery & Translational Research, Biomedical Research Foundation Academy of Athens, Athens, Greece., Andreakos E; Clinical, Experimental Surgery & Translational Research, Biomedical Research Foundation Academy of Athens, Athens, Greece., Hansson GK; Laboratory of Immunobiology, Cardiovascular Medicine Unit, Department of Medicine, Center for Molecular Medicine, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden., Malin S; Laboratory of Immunobiology, Cardiovascular Medicine Unit, Department of Medicine, Center for Molecular Medicine, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden., Olofsson PS; Laboratory of Immunobiology, Cardiovascular Medicine Unit, Department of Medicine, Center for Molecular Medicine, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden.; Institute of Bioelectronic Medicine, The Feinstein Institutes for Medical Research, Manhasset, New York, USA., Paulsson-Berne G; Laboratory of Immunobiology, Cardiovascular Medicine Unit, Department of Medicine, Center for Molecular Medicine, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden.

المصدر: Journal of internal medicine [J Intern Med] 2020 Sep; Vol. 288 (3), pp. 321-334. Date of Electronic Publication: 2020 May 14.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Blackwell Scientific Publications Country of Publication: England NLM ID: 8904841 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2796 (Electronic) Linking ISSN: 09546820 NLM ISO Abbreviation: J Intern Med Subsets: MEDLINE

مواضيع طبية MeSH: Atherosclerosis/*immunology , Atherosclerosis/*prevention & control , Hypercholesterolemia/*blood , Toll-Like Receptor 7/*physiology, Animals ; Antibodies/blood ; Aorta/pathology ; Apolipoproteins E/deficiency ; Apoptosis ; Atherosclerosis/pathology ; B-Lymphocytes/metabolism ; Cholesterol/blood ; Disease Models, Animal ; Immunoglobulin M/immunology ; Lipoproteins, LDL/immunology ; Mice, Knockout ; Necrosis ; Spleen/metabolism ; T-Lymphocytes, Regulatory/metabolism

المؤلفون: Hansson GK; Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden. goran.hansson@ki.se., Nilsson J; Department of Clinical Sciences Malmö, Lund University, Malmö, Sweden.

المصدر: Nature reviews. Cardiology [Nat Rev Cardiol] 2020 Aug; Vol. 17 (8), pp. 451-452.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101500075 Publication Model: Print Cited Medium: Internet ISSN: 1759-5010 (Electronic) Linking ISSN: 17595002 NLM ISO Abbreviation: Nat Rev Cardiol Subsets: MEDLINE

مواضيع طبية MeSH: Atherosclerosis*/immunology , Atherosclerosis*/prevention & control , Vaccines*, Animals ; Biomedical Research ; Disease Models, Animal ; Humans ; Mice ; Rabbits

المؤلفون: Nilsson J; From the Department of Clinical Sciences Malmö, Lund University, Sweden (J.N.)., Hansson GK; Department of Medicine, Karolinska University Hospital Solna, Karolinska Institute, Sweden (G.K.H.).

المصدر: Circulation research [Circ Res] 2020 Apr 24; Vol. 126 (9), pp. 1281-1296. Date of Electronic Publication: 2020 Apr 23.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Review

بيانات الدورية: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0047103 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1524-4571 (Electronic) Linking ISSN: 00097330 NLM ISO Abbreviation: Circ Res Subsets: MEDLINE

مواضيع طبية MeSH: Adaptive Immunity/*drug effects , Antibodies/*therapeutic use , Atherosclerosis/*drug therapy , B-Lymphocytes/*drug effects , Immunity, Innate/*drug effects , Inflammation/*drug therapy , T-Lymphocytes/*drug effects , Vaccines/*therapeutic use, Animals ; Antibodies/adverse effects ; Atherosclerosis/immunology ; Atherosclerosis/metabolism ; B-Lymphocytes/immunology ; B-Lymphocytes/metabolism ; Humans ; Inflammation/immunology ; Inflammation/metabolism ; Signal Transduction ; T-Lymphocytes/immunology ; T-Lymphocytes/metabolism ; Vaccines/adverse effects

المؤلفون: Libby P; Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts. Electronic address: plibby@bwh.harvard.edu., Hansson GK; Department of Medicine, Karolinska University Hospital Solna, Karolinska Institutet, Stockholm, Sweden.

المصدر: Journal of the American College of Cardiology [J Am Coll Cardiol] 2019 Sep 24; Vol. 74 (12), pp. 1594-1607.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review

بيانات الدورية: Publisher: Elsevier Biomedical Country of Publication: United States NLM ID: 8301365 Publication Model: Print Cited Medium: Internet ISSN: 1558-3597 (Electronic) Linking ISSN: 07351097 NLM ISO Abbreviation: J Am Coll Cardiol Subsets: MEDLINE

مواضيع طبية MeSH: Lipid Metabolism*, Atherosclerosis/*etiology , Inflammation/*etiology, Humans ; Thrombosis/complications

المؤلفون: Libby P; Department of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. plibby@bwh.harvard.edu., Buring JE; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA., Badimon L; Centre d'Investigació Cardiovascular CSIC-ICCC, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain., Hansson GK; Center for Molecular Medicine, Karolinska Universitetssjukhuset, Stockholm, Sweden., Deanfield J; Institute of Cardiovascular Sciences, University College London, London, UK., Bittencourt MS; Center for Clinical and Epidemiological Research, University Hospital, University of São Paulo, São Paulo, Brazil.; Faculdade Israelita de Ciencias da Saude Albert Einstein, São Paulo, Brazil.; DASA, São Paulo, Brazil., Tokgözoğlu L; Hacettepe University, Ankara, Turkey., Lewis EF; Department of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

المصدر: Nature reviews. Disease primers [Nat Rev Dis Primers] 2019 Aug 16; Vol. 5 (1), pp. 56. Date of Electronic Publication: 2019 Aug 16.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101672103 Publication Model: Electronic Cited Medium: Internet ISSN: 2056-676X (Electronic) Linking ISSN: 2056676X NLM ISO Abbreviation: Nat Rev Dis Primers Subsets: MEDLINE

مواضيع طبية MeSH: Atherosclerosis/*complications , Atherosclerosis/*physiopathology, Atherosclerosis/epidemiology ; Drug Therapy/methods ; Humans ; Hyperlipidemias/complications ; Hyperlipidemias/epidemiology ; Mass Screening/methods ; Risk Factors

المؤلفون: Centa M; Departments of Medicine and Center for Molecular Medicine (M.C., H.J., L.H., S.H., A.B., R.B., N.J.V., S.L.E., S.V.B, D.Y.L., C.S., G.K.H., D.F.J.K., F.W., L.M., S.G.M.), Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden., Jin H; Departments of Medicine and Center for Molecular Medicine (M.C., H.J., L.H., S.H., A.B., R.B., N.J.V., S.L.E., S.V.B, D.Y.L., C.S., G.K.H., D.F.J.K., F.W., L.M., S.G.M.), Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden., Hofste L; Departments of Medicine and Center for Molecular Medicine (M.C., H.J., L.H., S.H., A.B., R.B., N.J.V., S.L.E., S.V.B, D.Y.L., C.S., G.K.H., D.F.J.K., F.W., L.M., S.G.M.), Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden., Hellberg S; Departments of Medicine and Center for Molecular Medicine (M.C., H.J., L.H., S.H., A.B., R.B., N.J.V., S.L.E., S.V.B, D.Y.L., C.S., G.K.H., D.F.J.K., F.W., L.M., S.G.M.), Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden., Busch A; Departments of Medicine and Center for Molecular Medicine (M.C., H.J., L.H., S.H., A.B., R.B., N.J.V., S.L.E., S.V.B, D.Y.L., C.S., G.K.H., D.F.J.K., F.W., L.M., S.G.M.), Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden., Baumgartner R; Departments of Medicine and Center for Molecular Medicine (M.C., H.J., L.H., S.H., A.B., R.B., N.J.V., S.L.E., S.V.B, D.Y.L., C.S., G.K.H., D.F.J.K., F.W., L.M., S.G.M.), Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden., Verzaal NJ; Departments of Medicine and Center for Molecular Medicine (M.C., H.J., L.H., S.H., A.B., R.B., N.J.V., S.L.E., S.V.B, D.Y.L., C.S., G.K.H., D.F.J.K., F.W., L.M., S.G.M.), Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden., Lind Enoksson S; Departments of Medicine and Center for Molecular Medicine (M.C., H.J., L.H., S.H., A.B., R.B., N.J.V., S.L.E., S.V.B, D.Y.L., C.S., G.K.H., D.F.J.K., F.W., L.M., S.G.M.), Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden., Perisic Matic L; Molecular Medicine and Surgery (L.P.M., U.H.), Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden.; Center for Molecular Medicine (L.P.M., U.H.), Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden., Boddul SV; Departments of Medicine and Center for Molecular Medicine (M.C., H.J., L.H., S.H., A.B., R.B., N.J.V., S.L.E., S.V.B, D.Y.L., C.S., G.K.H., D.F.J.K., F.W., L.M., S.G.M.), Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden., Atzler D; Walther Straub Institute of Pharmacology and Toxicology, Medical Faculty, Ludwig-Maximilians-Universtät Munich (D.A.).; Institute for Cardiovascular Prevention, University Hospital Munich, Ludwig Maximilians University (D.A., E.L.)., Li DY; Departments of Medicine and Center for Molecular Medicine (M.C., H.J., L.H., S.H., A.B., R.B., N.J.V., S.L.E., S.V.B, D.Y.L., C.S., G.K.H., D.F.J.K., F.W., L.M., S.G.M.), Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden., Sun C; Departments of Medicine and Center for Molecular Medicine (M.C., H.J., L.H., S.H., A.B., R.B., N.J.V., S.L.E., S.V.B, D.Y.L., C.S., G.K.H., D.F.J.K., F.W., L.M., S.G.M.), Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden., Hansson GK; Departments of Medicine and Center for Molecular Medicine (M.C., H.J., L.H., S.H., A.B., R.B., N.J.V., S.L.E., S.V.B, D.Y.L., C.S., G.K.H., D.F.J.K., F.W., L.M., S.G.M.), Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden., Ketelhuth DFJ; Departments of Medicine and Center for Molecular Medicine (M.C., H.J., L.H., S.H., A.B., R.B., N.J.V., S.L.E., S.V.B, D.Y.L., C.S., G.K.H., D.F.J.K., F.W., L.M., S.G.M.), Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden., Hedin U; Molecular Medicine and Surgery (L.P.M., U.H.), Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden.; Center for Molecular Medicine (L.P.M., U.H.), Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden., Wermeling F; Departments of Medicine and Center for Molecular Medicine (M.C., H.J., L.H., S.H., A.B., R.B., N.J.V., S.L.E., S.V.B, D.Y.L., C.S., G.K.H., D.F.J.K., F.W., L.M., S.G.M.), Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden., Lutgens E; Institute for Cardiovascular Prevention, University Hospital Munich, Ludwig Maximilians University (D.A., E.L.).; Department of Medical Biochemistry, Amsterdam University Medical Centers, Amsterdam Cardiovascular Sciences, University of Amsterdam, The Netherlands (E.L.)., Binder CJ; Department of Laboratory Medicine, Medical University of Vienna (C.J.B.).; Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria (C.J.B.)., Maegdesfessel L; Departments of Medicine and Center for Molecular Medicine (M.C., H.J., L.H., S.H., A.B., R.B., N.J.V., S.L.E., S.V.B, D.Y.L., C.S., G.K.H., D.F.J.K., F.W., L.M., S.G.M.), Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden.; Technical University Munich, Department of Vascular and Endovascular Surgery and DZHK Partner Site, Germany (L.M.)., Malin SG; Departments of Medicine and Center for Molecular Medicine (M.C., H.J., L.H., S.H., A.B., R.B., N.J.V., S.L.E., S.V.B, D.Y.L., C.S., G.K.H., D.F.J.K., F.W., L.M., S.G.M.), Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden.

المصدر: Circulation [Circulation] 2019 May 21; Vol. 139 (21), pp. 2466-2482.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0147763 Publication Model: Print Cited Medium: Internet ISSN: 1524-4539 (Electronic) Linking ISSN: 00097322 NLM ISO Abbreviation: Circulation Subsets: MEDLINE

مواضيع طبية MeSH: Plaque, Atherosclerotic*, Aorta/*immunology , Aortic Diseases/*immunology , Atherosclerosis/*immunology , Germinal Center/*immunology , Immunoglobulin G/*immunology, Animals ; Antigens, CD19/genetics ; Antigens, CD19/metabolism ; Aorta/metabolism ; Aorta/pathology ; Aortic Diseases/genetics ; Aortic Diseases/metabolism ; Aortic Diseases/pathology ; Atherosclerosis/genetics ; Atherosclerosis/metabolism ; Atherosclerosis/pathology ; B-Lymphocytes/immunology ; B-Lymphocytes/metabolism ; Cell Proliferation ; Cells, Cultured ; Disease Models, Animal ; Gene Expression Regulation ; Germinal Center/metabolism ; Immunoglobulin G/metabolism ; Mice, Inbred C57BL ; Mice, Knockout, ApoE ; Positive Regulatory Domain I-Binding Factor 1/deficiency ; Positive Regulatory Domain I-Binding Factor 1/genetics ; Rupture, Spontaneous ; T-Lymphocytes/immunology ; T-Lymphocytes/metabolism