المؤلفون: Wu X; Department of Molecular Pharmacology, Faculty of Science and Engineering, University of Groningen, Antonius Deusinglaan 1, 9713AV, Groningen, the Netherlands; Groningen Research Institute for Asthma and COPD, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Ciminieri C; Department of Molecular Pharmacology, Faculty of Science and Engineering, University of Groningen, Antonius Deusinglaan 1, 9713AV, Groningen, the Netherlands; Groningen Research Institute for Asthma and COPD, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Bos IST; Department of Molecular Pharmacology, Faculty of Science and Engineering, University of Groningen, Antonius Deusinglaan 1, 9713AV, Groningen, the Netherlands; Groningen Research Institute for Asthma and COPD, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Woest ME; Department of Molecular Pharmacology, Faculty of Science and Engineering, University of Groningen, Antonius Deusinglaan 1, 9713AV, Groningen, the Netherlands; Groningen Research Institute for Asthma and COPD, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands; Aquilo BV, Antonius Deusinglaan 1, 9713AV, Groningen, the Netherlands., D'Ambrosi A; Department of Molecular Pharmacology, Faculty of Science and Engineering, University of Groningen, Antonius Deusinglaan 1, 9713AV, Groningen, the Netherlands; Groningen Research Institute for Asthma and COPD, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Wardenaar R; European Research Institute for the Biology of Ageing (ERIBA), University of Groningen, University Medical Center Groningen, 9713AV, Groningen, the Netherlands., Spierings DCJ; European Research Institute for the Biology of Ageing (ERIBA), University of Groningen, University Medical Center Groningen, 9713AV, Groningen, the Netherlands., Königshoff M; Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, USA., Schmidt M; Department of Molecular Pharmacology, Faculty of Science and Engineering, University of Groningen, Antonius Deusinglaan 1, 9713AV, Groningen, the Netherlands; Groningen Research Institute for Asthma and COPD, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Kistemaker LEM; Department of Molecular Pharmacology, Faculty of Science and Engineering, University of Groningen, Antonius Deusinglaan 1, 9713AV, Groningen, the Netherlands; Groningen Research Institute for Asthma and COPD, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands; Aquilo BV, Antonius Deusinglaan 1, 9713AV, Groningen, the Netherlands., Gosens R; Department of Molecular Pharmacology, Faculty of Science and Engineering, University of Groningen, Antonius Deusinglaan 1, 9713AV, Groningen, the Netherlands; Groningen Research Institute for Asthma and COPD, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands; Aquilo BV, Antonius Deusinglaan 1, 9713AV, Groningen, the Netherlands. Electronic address: r.gosens@rug.nl.

المصدر: Environmental pollution (Barking, Essex : 1987) [Environ Pollut] 2022 Jul 15; Vol. 305, pp. 119292. Date of Electronic Publication: 2022 Apr 18.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Applied Science Publishers Country of Publication: England NLM ID: 8804476 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-6424 (Electronic) Linking ISSN: 02697491 NLM ISO Abbreviation: Environ Pollut Subsets: MEDLINE

مواضيع طبية MeSH: Pulmonary Disease, Chronic Obstructive*/metabolism , beta Catenin*/metabolism, Epithelial Cells ; Fibroblasts/pathology ; Humans ; Lung/metabolism ; Vehicle Emissions/toxicity

المؤلفون: Hu Y; Division of Pulmonary Sciences and Critical Care Medicine, School of Medicine, University of Colorado, Aurora, Colorado, USA., Ng-Blichfeldt JP; Lung Repair and Regeneration Unit, Helmholtz-Zentrum Munich, Ludwig-Maximilians-University, University Hospital Grosshadern, Member of the German Center of Lung Research (DZL), Munich, Germany.; MRC Laboratory of Molecular Biology, Cambridge Biomedical Campus, Cambridge, UK., Ota C; Lung Repair and Regeneration Unit, Helmholtz-Zentrum Munich, Ludwig-Maximilians-University, University Hospital Grosshadern, Member of the German Center of Lung Research (DZL), Munich, Germany., Ciminieri C; Division of Pulmonary Sciences and Critical Care Medicine, School of Medicine, University of Colorado, Aurora, Colorado, USA.; Department of Molecular Pharmacology, Groningen Research Institute for Asthma and COPD (GRIAC), University of Groningen, Groningen, The Netherlands., Ren W; Division of Pulmonary Sciences and Critical Care Medicine, School of Medicine, University of Colorado, Aurora, Colorado, USA., Hiemstra PS; Department of Pulmonology, Leiden University Medical Center, Leiden, The Netherlands., Stolk J; Department of Pulmonology, Leiden University Medical Center, Leiden, The Netherlands., Gosens R; Department of Molecular Pharmacology, Groningen Research Institute for Asthma and COPD (GRIAC), University of Groningen, Groningen, The Netherlands., Königshoff M; Division of Pulmonary Sciences and Critical Care Medicine, School of Medicine, University of Colorado, Aurora, Colorado, USA.; Lung Repair and Regeneration Unit, Helmholtz-Zentrum Munich, Ludwig-Maximilians-University, University Hospital Grosshadern, Member of the German Center of Lung Research (DZL), Munich, Germany.

المصدر: Stem cells (Dayton, Ohio) [Stem Cells] 2020 Nov; Vol. 38 (11), pp. 1467-1478. Date of Electronic Publication: 2020 Jun 18.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 9304532 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1549-4918 (Electronic) Linking ISSN: 10665099 NLM ISO Abbreviation: Stem Cells Subsets: MEDLINE

مواضيع طبية MeSH: Emphysema/*genetics , Homeostasis/*physiology , Stem Cells/*metabolism , beta Catenin/*metabolism, Animals ; Emphysema/pathology ; Humans ; Mice ; Wnt Signaling Pathway

المؤلفون: Jansen SR; Department of Molecular Pharmacology, Groningen Research Institute for Pharmacy (GRIP), University of Groningen, Groningen, The Netherlands.; Institute of Experimental and Clinical Pharmacology and Toxicology, Medical Faculty Mannheim, University of Heidelberg, Heidelberg, Germany., Poppinga WJ; Department of Molecular Pharmacology, Groningen Research Institute for Pharmacy (GRIP), University of Groningen, Groningen, The Netherlands., de Jager W; Department of Molecular Pharmacology, Groningen Research Institute for Pharmacy (GRIP), University of Groningen, Groningen, The Netherlands., Lezoualc'h F; Inserm UMR-1048, Institut des Maladies Métaboliques et Cardiovasculaires, Université Toulouse III, Toulouse, France., Cheng X; Department of Integrative Biology & Pharmacology, Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, University of Texas, Houston, TX, USA., Wieland T; Institute of Experimental and Clinical Pharmacology and Toxicology, Medical Faculty Mannheim, University of Heidelberg, Heidelberg, Germany., Yarwood SJ; School of Life Sciences, Heriot-Watt University, Edinburgh, Scotland., Gosens R; Department of Molecular Pharmacology, Groningen Research Institute for Pharmacy (GRIP), University of Groningen, Groningen, The Netherlands., Schmidt M; Department of Molecular Pharmacology, Groningen Research Institute for Pharmacy (GRIP), University of Groningen, Groningen, The Netherlands.

المصدر: Oncotarget [Oncotarget] 2016 Jul 19; Vol. 7 (29), pp. 46354-46370.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Impact Journals Country of Publication: United States NLM ID: 101532965 Publication Model: Print Cited Medium: Internet ISSN: 1949-2553 (Electronic) Linking ISSN: 19492553 NLM ISO Abbreviation: Oncotarget Subsets: MEDLINE

مواضيع طبية MeSH: Carcinoma, Non-Small-Cell Lung/*pathology , Epithelial-Mesenchymal Transition/*physiology , Guanine Nucleotide Exchange Factors/*metabolism , Lung Neoplasms/*pathology , beta Catenin/*metabolism, Carcinoma, Non-Small-Cell Lung/metabolism ; Cell Line, Tumor ; Dinoprostone/metabolism ; Gene Expression Regulation, Neoplastic/physiology ; Humans ; Lung Neoplasms/metabolism ; Protein Transport ; Transcription, Genetic

المؤلفون: Jansen SR; Department of Molecular Pharmacology, University of Groningen, Groningen, The Netherlands; Department of Paediatrics, Department of Pediatric Oncology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands., Holman R, Hedemann I, Frankes E, Elzinga CR, Timens W, Gosens R, de Bont ES, Schmidt M

المصدر: Journal of cellular and molecular medicine [J Cell Mol Med] 2015 Jan; Vol. 19 (1), pp. 210-26. Date of Electronic Publication: 2014 Sep 30.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101083777 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1582-4934 (Electronic) Linking ISSN: 15821838 NLM ISO Abbreviation: J Cell Mol Med Subsets: MEDLINE

مواضيع طبية MeSH: Gene Amplification*, Dinoprostone/*pharmacology , Neuroblastoma/*metabolism , Neuroblastoma/*pathology , Nuclear Proteins/*metabolism , Oncogene Proteins/*metabolism , beta Catenin/*metabolism, Adolescent ; Apoptosis/drug effects ; Cell Cycle/drug effects ; Cell Line, Tumor ; Cell Survival/drug effects ; Child ; Child, Preschool ; Colforsin/pharmacology ; Cyclic AMP/pharmacology ; Cyclooxygenase 2 Inhibitors/pharmacology ; Female ; Humans ; Infant ; Male ; Mutant Proteins/metabolism ; N-Myc Proto-Oncogene Protein ; Nuclear Proteins/genetics ; Oncogene Proteins/genetics ; Protein Stability/drug effects ; Transcription, Genetic/drug effects ; Young Adult

المؤلفون: Kumawat K; University of Groningen, Groningen Research Institute for Asthma and COPD, Department of Molecular Pharmacology , A. Deusinglaan 1, 9713 AV Groningen , The Netherlands +31 50 363 8177 ; +31 50 363 6908 ; r.gosens@rug.nl., Koopmans T, Gosens R

المصدر: Expert opinion on therapeutic targets [Expert Opin Ther Targets] 2014 Sep; Vol. 18 (9), pp. 1023-34. Date of Electronic Publication: 2014 Jul 08.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Review

بيانات الدورية: Publisher: Informa Healthcare Country of Publication: England NLM ID: 101127833 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-7631 (Electronic) Linking ISSN: 14728222 NLM ISO Abbreviation: Expert Opin Ther Targets Subsets: MEDLINE

مواضيع طبية MeSH: Airway Remodeling/*physiology , Asthma/*physiopathology , beta Catenin/*metabolism, Animals ; Anti-Asthmatic Agents/pharmacology ; Asthma/drug therapy ; Bronchoconstriction/physiology ; Cell Differentiation/physiology ; Cell Proliferation/physiology ; Extracellular Matrix/metabolism ; Humans ; Molecular Targeted Therapy ; Wnt Signaling Pathway/physiology

المؤلفون: Kumawat K; Department of Molecular Pharmacology, University of Groningen, Groningen, the Netherlands; Groningen Research Institute for Asthma and COPD, University of Groningen, Groningen, the Netherlands., Menzen MH; Department of Molecular Pharmacology, University of Groningen, Groningen, the Netherlands; Groningen Research Institute for Asthma and COPD, University of Groningen, Groningen, the Netherlands., Slegtenhorst RM; Department of Molecular Pharmacology, University of Groningen, Groningen, the Netherlands; Groningen Research Institute for Asthma and COPD, University of Groningen, Groningen, the Netherlands., Halayko AJ; Departments of Physiology & Internal Medicine, University of Manitoba, Winnipeg, Canada., Schmidt M; Department of Molecular Pharmacology, University of Groningen, Groningen, the Netherlands; Groningen Research Institute for Asthma and COPD, University of Groningen, Groningen, the Netherlands., Gosens R; Department of Molecular Pharmacology, University of Groningen, Groningen, the Netherlands; Groningen Research Institute for Asthma and COPD, University of Groningen, Groningen, the Netherlands.

المصدر: PloS one [PLoS One] 2014 Apr 11; Vol. 9 (4), pp. e94801. Date of Electronic Publication: 2014 Apr 11 (Print Publication: 2014).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

مواضيع طبية MeSH: Gene Expression Regulation* , Signal Transduction*/drug effects, MAP Kinase Kinase Kinases/*metabolism , Myocytes, Smooth Muscle/*metabolism , Proto-Oncogene Proteins/*genetics , Sp1 Transcription Factor/*metabolism , Transforming Growth Factor beta/*metabolism , Wnt Proteins/*genetics , beta Catenin/*metabolism, Cell Line, Transformed ; Humans ; JNK Mitogen-Activated Protein Kinases/metabolism ; Protein Binding ; Wnt-5a Protein ; p38 Mitogen-Activated Protein Kinases/metabolism

المؤلفون: Baarsma HA; Department of Molecular Pharmacology, GRIAC research institute, University of Groningen, Groningen, The Netherlands., Königshoff M, Gosens R

المصدر: Pharmacology & therapeutics [Pharmacol Ther] 2013 Apr; Vol. 138 (1), pp. 66-83. Date of Electronic Publication: 2013 Jan 14.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Review

بيانات الدورية: Publisher: Pergamon Press Country of Publication: England NLM ID: 7905840 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-016X (Electronic) Linking ISSN: 01637258 NLM ISO Abbreviation: Pharmacol Ther Subsets: MEDLINE

مواضيع طبية MeSH: Wnt Signaling Pathway*, Wnt Proteins/*metabolism , beta Catenin/*metabolism, Animals ; Humans ; Ligands ; Transcription, Genetic

المؤلفون: Baarsma HA; Department of Molecular Pharmacology, University of Groningen, The Netherlands. h.a.baarsma@rug.nl, Menzen MH, Halayko AJ, Meurs H, Kerstjens HA, Gosens R

المصدر: American journal of physiology. Lung cellular and molecular physiology [Am J Physiol Lung Cell Mol Physiol] 2011 Dec; Vol. 301 (6), pp. L956-65. Date of Electronic Publication: 2011 Sep 09.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901229 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1504 (Electronic) Linking ISSN: 10400605 NLM ISO Abbreviation: Am J Physiol Lung Cell Mol Physiol Subsets: MEDLINE

مواضيع طبية MeSH: Signal Transduction*, Extracellular Matrix/*metabolism , Myocytes, Smooth Muscle/*metabolism , Transforming Growth Factor beta1/*pharmacology , beta Catenin/*metabolism, Bronchi/pathology ; Cell Line ; Fibronectins/metabolism ; Glycogen Synthase Kinase 3/metabolism ; Humans ; Lung Diseases, Obstructive/metabolism ; Lung Diseases, Obstructive/physiopathology ; Myocytes, Smooth Muscle/drug effects ; Perylene/analogs & derivatives ; Perylene/pharmacology ; RNA Interference ; Transcription, Genetic ; Transcriptional Activation ; Transforming Growth Factor beta1/physiology ; beta Catenin/antagonists & inhibitors ; beta Catenin/genetics

المؤلفون: Baarsma HA; Department of Molecular Pharmacology, University of Groningen, Groningen, The Netherlands. H.A.Baarsma@rug.nl, Spanjer AI, Haitsma G, Engelbertink LH, Meurs H, Jonker MR, Timens W, Postma DS, Kerstjens HA, Gosens R

المصدر: PloS one [PLoS One] 2011; Vol. 6 (9), pp. e25450. Date of Electronic Publication: 2011 Sep 30.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

مواضيع طبية MeSH: Fibroblasts/*drug effects , Lung/*pathology , Pulmonary Disease, Chronic Obstructive/*pathology , Signal Transduction/*drug effects , Transforming Growth Factor beta1/*pharmacology , Wnt Proteins/*metabolism , beta Catenin/*metabolism, Adaptor Proteins, Signal Transducing/genetics ; Aged ; Case-Control Studies ; Cell Differentiation/drug effects ; Cell Line ; Dishevelled Proteins ; Female ; Fibroblasts/cytology ; Fibroblasts/metabolism ; Fibroblasts/pathology ; Fibronectins/metabolism ; Frizzled Receptors/genetics ; Gene Expression Regulation/drug effects ; Humans ; Male ; Middle Aged ; Myofibroblasts/cytology ; Myofibroblasts/drug effects ; Myofibroblasts/pathology ; Phenotype ; Phosphoproteins/genetics ; Pulmonary Disease, Chronic Obstructive/metabolism

المؤلفون: Jansen SR; Dept. of Molecular Pharmacology, Univ. of Groningen, The Netherlands., Van Ziel AM, Baarsma HA, Gosens R

المصدر: American journal of physiology. Lung cellular and molecular physiology [Am J Physiol Lung Cell Mol Physiol] 2010 Aug; Vol. 299 (2), pp. L204-14. Date of Electronic Publication: 2010 May 14.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901229 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1504 (Electronic) Linking ISSN: 10400605 NLM ISO Abbreviation: Am J Physiol Lung Cell Mol Physiol Subsets: MEDLINE

مواضيع طبية MeSH: Indoles/*pharmacology , Maleimides/*pharmacology , Muscle Contraction/*drug effects , beta Catenin/*physiology, Actins/metabolism ; Animals ; Cadherins/metabolism ; Cattle ; Cell Membrane/metabolism ; Glycogen Synthase Kinase 3/antagonists & inhibitors ; Lithium Chloride/pharmacology ; Muscle Contraction/physiology ; Muscle, Smooth/physiology ; Myosin Heavy Chains/metabolism ; Organ Culture Techniques ; Perylene/analogs & derivatives ; Perylene/pharmacology ; Trachea/physiology ; beta Catenin/metabolism