المؤلفون: Natalia S. Nemeria, Frank Jordan, Chunli Yu, Xu Zhang, Sander M. Houten, Robert J. DeVita, Ronald C. Hendrickson, João Leandro, Jan Aten, Tetyana Dodatko, Roberto Sanchez

المساهمون: Pathology, Biomedical Engineering and Physics, Graduate School, ACS - Atherosclerosis & ischemic syndromes

المصدر: Leandro, J, Dodatko, T, Aten, J, Nemeria, N S, Zhang, X, Jordan, F, Hendrickson, R C, Sanchez, R, Yu, C, DeVita, R J & Houten, S M 2020, ' DHTKD1 and OGDH display substrate overlap in cultured cells and form a hybrid 2-oxo acid dehydrogenase complex in vivo ', Human Molecular Genetics, vol. 29, no. 7, pp. 1168-1179 . https://doi.org/10.1093/HMG/DDAA037
Human molecular genetics, 29(7), 1168-1179. Oxford University Press
Hum Mol Genet
Human Molecular Genetics, 29(7), 1168-1179. Oxford University Press

مصطلحات موضوعية: Coenzyme A, Dehydrogenase, Biology, Substrate Specificity, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Oxidoreductase, Genetics, Humans, DHTKD1, Ketoglutarate Dehydrogenase Complex, Amino Acid Metabolism, Inborn Errors, Molecular Biology, Cells, Cultured, Genetics (clinical), 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, Dihydrolipoamide dehydrogenase, Glutaryl-CoA Dehydrogenase, Brain Diseases, Metabolic, Ketone Oxidoreductases, General Medicine, General Article One, HEK293 Cells, Biochemistry, chemistry, OGDH, Acyl Coenzyme A, Oxoglutarate dehydrogenase complex, 030217 neurology & neurosurgery, Glutaric Acidemia Type 1

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4b211cbfed828d5e97d2e00a37a3975
https://doi.org/10.1093/hmg/ddaa037

المؤلفون: Carmen Argmann, Hongjie Chen, Chunli Yu, Tetyana Dodatko, Sander M. Houten, Michelle Puchowicz, Dipankar Bhattacharya, Sara Violante, Scott L. Friedman, Pablo Ranea-Robles

المصدر: Cell Mol Life Sci

مصطلحات موضوعية: Male, Omega oxidation, Mitochondrion, Peroxisomal Bifunctional Enzyme, Article, Lipid Metabolism, Inborn Errors, Cellular and Molecular Neuroscience, chemistry.chemical_compound, Mice, Biosynthesis, ABCD3, Animals, Homeostasis, Humans, Dicarboxylic Acids, Molecular Biology, Beta oxidation, chemistry.chemical_classification, Pharmacology, Mice, Knockout, biology, Liver Diseases, Cell Biology, Metabolism, Peroxisome, Mitochondria, Mice, Inbred C57BL, Enzyme, Cholesterol, HEK293 Cells, chemistry, Biochemistry, biology.protein, Molecular Medicine, ACOX1, Female

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::754c093387caecb52b1699e91f3ef013
https://europepmc.org/articles/PMC8263512/

المؤلفون: Michelle R. Arkin, João Leandro, Christopher G. Wilson, Sander M. Houten, Hui Wang, Michael B. Lazarus, Robert J. DeVita, Frank Jordan, Tetyana Dodatko, Brandon Stauffer, Roberto Sanchez, Natalia S. Nemeria, Chunli Yu, Chalada Suebsuwong, Susmita Khamrui, Moses Moustakim, Wang M, Cody Secor, Khoi Huynh

المصدر: ACS chemical biology, vol 15, iss 8
ACS Chem Biol

مصطلحات موضوعية: 0301 basic medicine, Dimer, Lysine, Crystal structure, Crystallography, X-Ray, 01 natural sciences, Biochemistry, chemistry.chemical_compound, 0302 clinical medicine, Charcot-Marie-Tooth Disease, 2.1 Biological and endogenous factors, Aetiology, chemistry.chemical_classification, 0303 health sciences, Crystallography, Molecular Structure, Chemistry, Circular Dichroism, General Medicine, Biological Sciences, Small molecule, 3. Good health, Molecular Medicine, High-throughput screening, Mutation, Missense, complex mixtures, Article, 2-oxoadipic aciduria, 03 medical and health sciences, Rare Diseases, Genetics, DHTKD1, Humans, Ketoglutarate Dehydrogenase Complex, Enzyme kinetics, 030304 developmental biology, Cofactor binding, 010405 organic chemistry, Catabolism, Organic Chemistry, Wild type, Tryptophan, Neurosciences, 0104 chemical sciences, 030104 developmental biology, Enzyme, Orphan Drug, Mutation, Chemical Sciences, X-Ray, bacteria, Dehydrogenase complex, Thiamine Pyrophosphate, Missense, 030217 neurology & neurosurgery

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db1ec499ee06b35d557c41e6c15f5e44
https://escholarship.org/uc/item/5dj5p5mg

المؤلفون: Yongteng Zhao, Jing Cui, Du-bo Zhong, Xuya Yu, Chunli Yu

المصدر: Bioresource technology. 305

مصطلحات موضوعية: 0106 biological sciences, Environmental Engineering, Pluvialis, chemistry.chemical_element, Bioengineering, 010501 environmental sciences, Calcium, 01 natural sciences, Melatonin, chemistry.chemical_compound, Astaxanthin, 010608 biotechnology, medicine, Waste Management and Disposal, 0105 earth and related environmental sciences, chemistry.chemical_classification, Reactive oxygen species, Haematococcus pluvialis, biology, Renewable Energy, Sustainability and the Environment, Abiotic stress, Nitrogen deficiency, General Medicine, biology.organism_classification, Biochemistry, chemistry, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a463be5cb61d20737fb4c9e46af3b5d
https://pubmed.ncbi.nlm.nih.gov/32114308

المؤلفون: Sander M. Houten, Tetyana Dodatko, Roberto Sanchez, Robert J. DeVita, Ronald C. Hendrickson, João Leandro, Jan Aten, Chunli Yu

مصطلحات موضوعية: chemistry.chemical_classification, 0303 health sciences, Chemistry, Kinetics, Substrate (chemistry), Dehydrogenase, Glutaric aciduria type 1, medicine.disease, 03 medical and health sciences, 0302 clinical medicine, Enzyme, Biochemistry, In vivo, medicine, OGDH, DHTKD1, 030217 neurology & neurosurgery, 030304 developmental biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc6d8ff91d9d43f81841557e0a6df882

المؤلفون: Yongteng Zhao, Delu Ning, Hui-Ping Wang, Shuxiang Geng, Ting Ma, Benyong Han, Wei Ding, Xuya Yu, Chunli Yu

المصدر: Bioresource Technology. 319:124150

مصطلحات موضوعية: 0106 biological sciences, Environmental Engineering, Antioxidant, Linoleic acid, medicine.medical_treatment, Bioengineering, Xanthophylls, 010501 environmental sciences, 01 natural sciences, Melatonin, chemistry.chemical_compound, Chlorophyceae, Astaxanthin, 010608 biotechnology, medicine, Glycolysis, Waste Management and Disposal, 0105 earth and related environmental sciences, chemistry.chemical_classification, Haematococcus pluvialis, Reactive oxygen species, biology, Renewable Energy, Sustainability and the Environment, Chemistry, General Medicine, biology.organism_classification, Lipids, Citric acid cycle, Biochemistry, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11d02a60f7a8e889ef6a9d7548cd66c6
https://doi.org/10.1016/j.biortech.2020.124150

المؤلفون: Hui Zhou, Qin Sun, Chunli Yu

المصدر: North American journal of medicinescience. 6(4)

مصطلحات موضوعية: chemistry.chemical_classification, Newborn screening, biology, business.industry, Molecular biology, Enzyme assay, Article, Dried blood spot, Enzyme, Biochemistry, chemistry, Clinical diagnosis, biology.protein, Effective treatment, Medicine, Multiplex, business, Specific enzyme

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::beaf84b526c44253744d8a7706f51d50
https://pubmed.ncbi.nlm.nih.gov/27293520

المؤلفون: Yanlin Wang, Bronwyn Atcheson, Gary W. Cline, Chunli Yu, Dongyan Zhang, Haihong Zong, Gregory J. Cooney, Gerald I. Shulman, Morris F. White, Jason K. Kim, Yan Chen, Edward W. Kraegen, Raynald Bergeron, Samuel W. Cushman

المصدر: Journal of Biological Chemistry. 277:50230-50236

مصطلحات موضوعية: Male, Fat Emulsions, Intravenous, medicine.medical_specialty, Fatty Acids, Nonesterified, Biochemistry, Diglycerides, Phosphatidylinositol 3-Kinases, chemistry.chemical_compound, Insulin resistance, Insulin receptor substrate, Internal medicine, Free fatty acid receptor 1, medicine, Animals, Insulin, Phosphorylation, Rats, Wistar, Muscle, Skeletal, Phosphotyrosine, Molecular Biology, Diacylglycerol kinase, chemistry.chemical_classification, biology, Fatty acid, Tyrosine phosphorylation, Cell Biology, Phosphoproteins, medicine.disease, Rats, IRS1, Kinetics, Insulin receptor, Endocrinology, chemistry, Insulin Receptor Substrate Proteins, biology.protein, lipids (amino acids, peptides, and proteins)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f68bd295ddba704586d1ff6bde565e2
https://doi.org/10.1074/jbc.m200958200