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المؤلفون: Xiaodong Zhu, Mingyang Yuan, Kung-Hsien Ho, Ruiying Hu, Guoqiang Gu, Irina Kaverina
المصدر: PLoS ONE
PLoS ONE, Vol 16, Iss 7, p e0241939 (2021)مصطلحات موضوعية: 0301 basic medicine, Physiology, GTP-Binding Protein alpha Subunits, medicine.medical_treatment, Cell, GTP-Binding Protein alpha Subunits, Gi-Go, Biochemistry, Microtubules, chemistry.chemical_compound, Mice, 0302 clinical medicine, Endocrinology, Insulin-Secreting Cells, Insulin Secretion, Medicine and Health Sciences, Insulin, Electron Microscopy, Cells, Cultured, Cellular Senescence, Mice, Knockout, Microscopy, Mice, Inbred ICR, Multidisciplinary, geography.geographical_feature_category, Chemistry, Organic Compounds, Nocodazole, Monosaccharides, Islet, Cell biology, medicine.anatomical_structure, Physical Sciences, Medicine, Cellular Structures and Organelles, Research Article, Signal Transduction, Science, Carbohydrates, 030209 endocrinology & metabolism, Biosynthesis, Research and Analysis Methods, 03 medical and health sciences, stomatognathic system, Microtubule, medicine, Animals, Secretion, Vesicles, Diabetic Endocrinology, geography, Endocrine Physiology, Secretory Vesicles, Organic Chemistry, Cell Membrane, Chemical Compounds, Biology and Life Sciences, Biological Transport, Cell Biology, Hormones, 030104 developmental biology, Glucose, Metabolism, Transmission Electron Microscopy, Physiological Processes, Function (biology)
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المؤلفون: Everardo M. Carneiro, Thiago R. Araujo, Israelle N. Freitas, Jean Franciesco Vettorazzi, E. A. Magalhães, Maria Lúcia Bonfleur, Rosane Aparecida Ribeiro
المصدر: Amino Acids. 51:727-738
مصطلحات موضوعية: Male, 0301 basic medicine, Taurine, medicine.medical_specialty, Offspring, medicine.medical_treatment, Clinical Biochemistry, Endocrine System, Diet, High-Fat, Biochemistry, Islets of Langerhans, Mice, 03 medical and health sciences, chemistry.chemical_compound, Internal medicine, Glucose Intolerance, Insulin Secretion, medicine, Animals, Homeostasis, Endocrine system, Glucose homeostasis, Obesity, geography, geography.geographical_feature_category, 030102 biochemistry & molecular biology, business.industry, Insulin, Organic Chemistry, Pancreatic Diseases, medicine.disease, Islet, Sperm, Mice, Inbred C57BL, 030104 developmental biology, Endocrinology, chemistry, Dietary Supplements, business
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المؤلفون: John J. Priatel, C. Bruce Verchere, Galina Soukhatcheva, Mercè Obach, Derek L. Dai, Azadeh Hosseini-Tabatabaei, Joel Montane, Paul C. Orban, Katarina Wind
المصدر: Molecular and Cellular Endocrinology. 477:48-56
مصطلحات موضوعية: Graft Rejection, Monocarboxylic Acid Transporters, 0301 basic medicine, endocrine system, endocrine system diseases, Islets of Langerhans Transplantation, X-Linked Inhibitor of Apoptosis Protein, Inhibitor of apoptosis, Biochemistry, Injections, Immunomodulation, Mice, 03 medical and health sciences, chemistry.chemical_compound, Endocrinology, Mice, Inbred NOD, Insulin-Secreting Cells, Lactate dehydrogenase, Insulin Secretion, Immune Tolerance, Animals, Humans, Insulin, Medicine, Lactic Acid, Molecular Biology, geography, geography.geographical_feature_category, L-Lactate Dehydrogenase, Symporters, biology, business.industry, Allografts, medicine.disease, Streptozotocin, Islet, Rats, XIAP, Diabetes Mellitus, Type 1, Glucose, 030104 developmental biology, Monocarboxylate transporter 1, chemistry, biology.protein, Cancer research, Beta cell, business, Insulitis, medicine.drug
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المؤلفون: Brian T. Layden, Elizabeth D. Cox, Miles H Fuller, Erin Guthery, Yanlong Zhu, Chinmai Patibandla, Michael D. Schaid, Austin Reuter, Dudley W. Lamming, Joshua C. Neuman, Rachel J. Fenske, Michelle E. Kimple, Nicole E. Richardson, Ying Ge, Harpreet K Sandhu, Dawn Belt Davis, Irene M. Ong, Allan R. Brasier
المصدر: Metabolites
Volume 11
Issue 1
Metabolites, Vol 11, Iss 58, p 58 (2021)مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, obesity, insulin secretion, endocrine system diseases, Endocrinology, Diabetes and Metabolism, lcsh:QR1-502, Prostaglandin, Incretin, gut microbiome, 030209 endocrinology & metabolism, Type 2 diabetes, Biology, Biochemistry, lcsh:Microbiology, Article, prostaglandins, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Insulin resistance, Downregulation and upregulation, Internal medicine, insulin resistance, Genetic model, medicine, Prostaglandin E2, Molecular Biology, geography, geography.geographical_feature_category, beta-cell function, digestive, oral, and skin physiology, Islet, medicine.disease, untargeted plasma metabolomics, 030104 developmental biology, Endocrinology, chemistry, inflammation, lipids (amino acids, peptides, and proteins), type 2 diabetes, medicine.drug, polyunsaturated fatty acids
وصف الملف: application/pdf
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المؤلفون: Anne Wojtusciszyn, Eva Gatineau, Blaz Lupse, Amin Ardestani, Huan Liu, Paulina Karen Mendoza Sanchez, Patrick Gilon, Ralf Dringen, Mona Khazaei, Shirin Geravandi, Kathrin Maedler
المساهمون: UCL - SSS/IREC/EDIN - Pôle d'endocrinologie, diabète et nutrition
المصدر: Biochemical and biophysical research communications, Vol. 568, p. 158-166 (2021)
Biochem Biophys Res Communمصطلحات موضوعية: medicine.medical_specialty, endocrine system, LDH, medicine.medical_treatment, Biophysics, Biochemistry, Glucagon, Article, LDHA, chemistry.chemical_compound, Downregulation and upregulation, Lactate dehydrogenase, Internal medicine, Insulin Secretion, medicine, Humans, Secretion, RNA, Messenger, Molecular Biology, Cells, Cultured, geography, geography.geographical_feature_category, L-Lactate Dehydrogenase, Chemistry, Pancreatic islets, Insulin, Beta-cell, Diabetes, Cell Biology, Islet, Up-Regulation, Endocrinology, medicine.anatomical_structure, Glucose, Diabetes Mellitus, Type 2, Glucagon-Secreting Cells, Lactate, Beta cell, Islets
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38a6770995f7d59278ddba34b9970f8d
https://hdl.handle.net/2078.1/249232 -
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المؤلفون: Aine McKillop, Nigel Irwin, Andrew McCloskey, Peter R. Flatt, R. Charlotte Moffett, Shruti Mohan
المصدر: Biochimica et biophysica acta. General subjects. 1865(3)
مصطلحات موضوعية: 0301 basic medicine, Blood Glucose, Male, medicine.medical_treatment, Type 2 diabetes, Oxytocin, Biochemistry, chemistry.chemical_compound, Mice, 0302 clinical medicine, Insulin Secretion, Insulin, geography.geographical_feature_category, Protein Stability, Islet, Female, Beta cell, Oligopeptides, medicine.drug, Half-Life, medicine.medical_specialty, Biophysics, 030209 endocrinology & metabolism, Diet, High-Fat, Diabetes Mellitus, Experimental, 03 medical and health sciences, Islets of Langerhans, In vivo, Internal medicine, medicine, Animals, Hypoglycemic Agents, Obesity, Molecular Biology, Triglycerides, geography, Triglyceride, Cholesterol, HDL, Cholesterol, LDL, medicine.disease, Glucagon, 030104 developmental biology, Endocrinology, chemistry, Diabetes Mellitus, Type 2, Insulin Resistance, Energy Intake, Hormone
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المؤلفون: Chun-Kwok Wong, Xiao Yu Tian, Dandan Mao, Di Mao, Clara Bik-San Lau, Sze Wan Hung, Juliana C.N. Chan, Wing Hung Tam, Ronald C.W. Ma, Xing Ming, Huanyi Cao, Chi Chiu Wang, Elaine Chow, Alice P.S. Kong, Paul K.S. Chan, Joshua Jing Xi Li, Heung Man Lee, Guy A. Rutter
المصدر: J Biol Chem
مصطلحات موضوعية: 0301 basic medicine, Interleukin-1beta, Inflammation, IκB kinase, Pharmacology, Biochemistry, Cell Line, 03 medical and health sciences, chemistry.chemical_compound, Mice, In vivo, Diabetes mellitus, Insulin-Secreting Cells, Insulin Secretion, medicine, Animals, Obesity, Molecular Biology, geography, geography.geographical_feature_category, 030102 biochemistry & molecular biology, Chemistry, Plant Extracts, Ophiopogon, Transcription Factor RelA, NF-κB, Cell Biology, medicine.disease, Islet, Dietary Fats, I-kappa B Kinase, Plant Tubers, 030104 developmental biology, medicine.anatomical_structure, medicine.symptom, Beta cell, Pancreas
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11a01f4a484be6b7c014547dcbbd4276
https://pubmed.ncbi.nlm.nih.gov/32605924 -
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المؤلفون: Daniel Norman, Carl Johan Drott, Daniel Espes
المصدر: Peptides. 135
مصطلحات موضوعية: Blood Glucose, Chromium, Male, Fysiologi, Physiology, Biochemistry, Rats, Sprague-Dawley, chemistry.chemical_compound, Pancreatic blood flow, 0302 clinical medicine, Endocrinology, vascular, immune system diseases, Insulin-Secreting Cells, Insulin Secretion, CART, blood flow, Insulin, Amino Acids, Neurotransmitter, media_common, geography.geographical_feature_category, virus diseases, Islet, Receptor, Endothelin A, medicine.anatomical_structure, Carbohydrate Metabolism, Cart, medicine.medical_specialty, Endothelin A Receptor Antagonists, media_common.quotation_subject, 030209 endocrinology & metabolism, Nerve Tissue Proteins, Peptides, Cyclic, 03 medical and health sciences, Cellular and Molecular Neuroscience, Islets of Langerhans, Internal medicine, parasitic diseases, mental disorders, medicine, Animals, Humans, Pancreas, Anesthetics, geography, pancreatic islets, business.industry, Addiction, Pancreatic islets, Nicotinic Acids, Blood flow, Glucose Tolerance Test, Rats, Glucose, nervous system, chemistry, Regional Blood Flow, business, 030217 neurology & neurosurgery, Hormone
وصف الملف: application/pdf
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المؤلفون: Jordi Altirriba, Sarah Mouche, Charlotte Barbieux, Ildiko Szanto, Christelle Veyrat-Durebex, Chris R. J. Kennedy, Domenico Bosco, Gerhard Christofori, Chet E. Holterman, Jenny E. Gunton, Thierry Berney, Alexis Forterre, Michel Pinget, Karim Bouzakri, William Bietiger, Mohamed Alibashe, Benjamin B. Tournier, Caroline Arous
المساهمون: Diabète et thérapies cellulaires (DIATHEC), Université de Strasbourg (UNISTRA)
المصدر: Antioxidants and Redox Signaling
Antioxidants and Redox Signaling, Mary Ann Liebert, 2020, 32 (9), pp.618-635. ⟨10.1089/ars.2018.7579⟩مصطلحات موضوعية: Male, 0301 basic medicine, medicine.medical_specialty, Physiology, medicine.medical_treatment, Clinical Biochemistry, Diet, High-Fat, Biochemistry, Islets of Langerhans, Mice, 03 medical and health sciences, chemistry.chemical_compound, Diabetes mellitus, Internal medicine, Insulin Secretion, medicine, Animals, Humans, Molecular Biology, Cells, Cultured, General Environmental Science, chemistry.chemical_classification, Oxidase test, Reactive oxygen species, geography, NADPH oxidase, geography.geographical_feature_category, 030102 biochemistry & molecular biology, biology, Insulin, Cell Biology, medicine.disease, Islet, 3. Good health, Mice, Inbred C57BL, 030104 developmental biology, Endocrinology, NADPH Oxidase 5, chemistry, Mice, Inbred CBA, biology.protein, General Earth and Planetary Sciences, Female, Beta cell, Nicotinamide adenine dinucleotide phosphate, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dfd6911e073298d180d271322f3a5c8
https://hal.archives-ouvertes.fr/hal-03336125 -
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المؤلفون: Grant M. Kelly, Kathryn A. Carbajal, Dudley W. Lamming, Michelle E. Kimple, Erin Guthery, Shannon J. Gallagher, Allison L. Brill, Joshua C. Neuman, Darby C. Peter, Cara L Green, Molly L. Wehner, Michael D. Schaid, Austin Reuter, Jeffrey M. Harrington
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: IBMX, 3-isobutyl-1-methylxanthine, Blood Glucose, Male, 0301 basic medicine, insulin secretion, HFD, high-fat diet, FBKO, Gαz full-body KO mice on the B6N background, Biochemistry, AUC, area under the curve, Mice, chemistry.chemical_compound, insulin resistance, Insulin-Secreting Cells, Prostaglandin E2, OGTTs, oral glucose tolerance tests, Mice, Knockout, Regulation of gene expression, EIA, enzyme immunoassay, geography.geographical_feature_category, diabetes, Chemistry, SDE, significantly differentially expressed, Ex4, exendin-4, HRP, horseradish peroxidase, qRT-PCR, quantitative real-time PCR, Gαz, G protein alpha-subunit, Islet, GTP-Binding Protein alpha Subunits, GPCRs, G protein–coupled receptors, CD, control diet, EP3, prostaglandin EP3 receptor, Beta cell, Research Article, medicine.drug, medicine.medical_specialty, G protein, βKO, beta-cell–specific Gαz-null, Prostaglandin, T2D, type 2 diabetes, Diet, High-Fat, KEGG, Kyoto Encyclopedia of Genes and Genomes, B6N, C57BL/6N, GLP1R, glucagon-like peptide 1 receptor, GSIS, glucose-stimulated insulin secretion, 03 medical and health sciences, Insulin resistance, Downregulation and upregulation, cAMP, B6J, C57BL/6J, Internal medicine, PGE2, prostaglandin E2, medicine, cell signaling, Animals, Obesity, Molecular Biology, geography, 030102 biochemistry & molecular biology, G protein–coupled receptor (GPCR), Cell Biology, medicine.disease, BCA, bicinchoninic acid, Mice, Inbred C57BL, Disease Models, Animal, HA-EP3γ, hemagglutinin-tagged EP3γ, 030104 developmental biology, Endocrinology, Diabetes Mellitus, Type 2, ITTs, insulin tolerance tests, KRBB, Krebs-Ringer bicarbonate buffer, RIA, radioimmunoassay
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6d299e7f361025fcb5f8c430f86202b
https://doi.org/10.1074/jbc.ra120.015585