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المؤلفون: Maria Demontis, Silvia A. Ferreira, Rosie M. Butler, Christine L. Jones, Tracey J. Mitchell, Isabella Tosi, Charlotte E. Flanagan, Robert C.T. McKenzie, Wesley J. Woollard, Sean Whittaker, Susan D. John
المصدر: Butler, R M, Mckenzie, R C, Jones, C L, Flanagan, C E, Woollard, W J, Demontis, M, Ferreira, S, Tosi, I, John, S, Whittaker, S J & Mitchell, T J 2019, ' Contribution of STAT3 and RAD23B in Primary Sézary Cells to Histone Deacetylase Inhibitor FK228 Resistance ', Journal of Investigative Dermatology, vol. 139, no. 9, pp. 1975-1984.e2 . https://doi.org/10.1016/j.jid.2019.03.1130
مصطلحات موضوعية: 0301 basic medicine, CD4-Positive T-Lymphocytes, STAT3 Transcription Factor, Skin Neoplasms, DNA Copy Number Variations, medicine.drug_class, Primary Cell Culture, Apoptosis, Dermatology, Biochemistry, Polymorphism, Single Nucleotide, Romidepsin, 03 medical and health sciences, 0302 clinical medicine, Depsipeptides, medicine, Tumor Cells, Cultured, Humans, Sezary Syndrome, Phosphorylation, Molecular Biology, Vorinostat, Sezary Cell, Skin, Regulation of gene expression, Chemistry, Histone deacetylase inhibitor, Cutaneous T-cell lymphoma, Cell Biology, HDACi, STAT3, RAD23, Sezary Syndrome, CTCL, JAK, primary T cells, medicine.disease, Neoplastic Cells, Circulating, DNA-Binding Proteins, Gene Expression Regulation, Neoplastic, Histone Deacetylase Inhibitors, 030104 developmental biology, Trichostatin A, DNA Repair Enzymes, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, Gene Knockdown Techniques, Cancer research, Tyrosine, Histone deacetylase, medicine.drug
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URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c639eeccf4bbbe400c2de80d80080b01
https://kclpure.kcl.ac.uk/ws/files/110043202/PIIS0022202X19313405.pdf -
2T-cell receptor early signalling complex activation in response to interferon-α receptor stimulation
المؤلفون: Claire Stevens, Susan D. John, Zamal Ahmed, John E. Ladbury, C. Tatiana Baldari, Orso Maria Lucherini, Ann Marie Simeone
المصدر: Biochemical Journal
مصطلحات موضوعية: MAPK/ERK pathway, T-Lymphocytes, Vav, Receptor, Interferon alpha-beta, Biochemistry, Janus kinase/signal transducer and activator of transcription pathway (JAK/STAT pathway), IFNR, interferon receptor, RFP, red fluorescent protein, Jurkat Cells, 0302 clinical medicine, cytokine, Phosphorylation, Receptor, IFNα, interferon-α, 0303 health sciences, Chemistry, Kinase, RLU, relative light unit, Cell biology, STAT, signal transducer and activator of transcription, 030220 oncology & carcinogenesis, Signal transduction, NF-κB, nuclear factor κB, Mitogen-Activated Protein Kinases, JAK, Janus kinase, TCR, Research Article, Signal Transduction, PBMC, peripheral blood mononuclear cell, mitogen-activated protein kinase pathway (MAPK pathway), Receptors, Antigen, T-Cell, T cell, signal transduction, IFNαR, IFNα receptor, ERK, extracellular-signal-regulated kinase, Transfection, 03 medical and health sciences, FBS, fetal bovine serum, LAT, linker for activation of T-cells, Humans, Protein kinase A, Molecular Biology, ESC, early signalling complex, 030304 developmental biology, Adaptor Proteins, Signal Transducing, T-cell receptor, T-cell receptor early signalling complex (TCR ESC), Cell Biology, Phosphoproteins, IL, interleukin, NFAT, nuclear factor of activated T-cells, TCR, T-cell receptor, MEK, MAPK/ERK kinase, STAT protein, Cancer research, Janus kinase, interferon-α receptor (IFNαR), NP-40, Nonidet P40, MAPK, mitogen-activated protein kinase, Slp76
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94f61ec5e411dc9beda3dc9b81ce4909
http://europepmc.org/articles/PMC2888567 -
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المؤلفون: Björn Schuster, Susan D. John, Steven Lynham, Lisa Hendry, Malcolm Ward, Helen Byers
المصدر: King's College London
مصطلحات موضوعية: medicine.medical_treatment, Commentary Article, Biology, Kidney, Transfection, Biochemistry, Mass Spectrometry, Cell Line, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Myeloid Cell Differentiation, Cell Line, Tumor, AEBSF, STAT5 Transcription Factor, medicine, Humans, Protein Isoforms, Molecular Biology, Conserved Sequence, STAT5, 030304 developmental biology, Serine protease, 0303 health sciences, Protease, Cell growth, Tumor Suppressor Proteins, Proteolytic enzymes, Reproducibility of Results, Cell Biology, Molecular biology, Recombinant Proteins, Alternative Splicing, chemistry, Leukemia, Myeloid, biology.protein, STAT protein, Chromatography, Liquid, Peptide Hydrolases, Research Article, 030215 immunology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04b12e6b8a6bfa654af629ea5e974892
https://doi.org/10.1042/bj20061877 -
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المؤلفون: Sean Whittaker, Machteld M. Tiemessen, Lisa Hendry, Leonie S. Taams, Susan D. John, Tracey J. Mitchell
المصدر: Journal of Investigative Dermatology. 126:2217-2223
مصطلحات موضوعية: Male, Skin Neoplasms, Lymphocyte, chemical and pharmacologic phenomena, Dermatology, Biology, T-Lymphocytes, Regulatory, Biochemistry, Article, 03 medical and health sciences, 0302 clinical medicine, Antigens, CD, medicine, Humans, CTLA-4 Antigen, RNA, Messenger, IL-2 receptor, Molecular Biology, Sezary Cell, Aged, Neoplasm Staging, 030304 developmental biology, 0303 health sciences, Mycosis fungoides, Cutaneous T-cell lymphoma, FOXP3, Forkhead Transcription Factors, hemic and immune systems, Cell Biology, T lymphocyte, Middle Aged, medicine.disease, Antigens, Differentiation, Lymphoma, T-Cell, Cutaneous, 3. Good health, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Immunology, Female, Ex vivo
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المؤلفون: Uwe Vinkemeier, Susan D. John, Andreas Begitt, Thomas Meyer, Lisa Hendry
المصدر: Journal of Biological Chemistry. 279:18998-19007
مصطلحات موضوعية: Biology, Transfection, Biochemistry, Dephosphorylation, chemistry.chemical_compound, Transcription (biology), STAT5 Transcription Factor, Humans, STAT1, Phosphorylation, Tyrosine, Binding site, Phosphotyrosine, Molecular Biology, Cell Nucleus, Tumor Suppressor Proteins, Nuclear Proteins, Tyrosine phosphorylation, Promoter, Cell Biology, Milk Proteins, Cell biology, DNA-Binding Proteins, STAT1 Transcription Factor, Gene Expression Regulation, chemistry, Mutagenesis, Site-Directed, Trans-Activators, STAT protein, biology.protein, Dimerization, HeLa Cells, Transcription Factors
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5260877c86f0b2abc2416f7b714fdc16
https://doi.org/10.1074/jbc.m400766200 -
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المؤلفون: Warren J. Leonard, Jian-Xin Lin, Susan D. John, William S. Modi, Judy A. Mietz
المصدر: Journal of Biological Chemistry. 271:10738-10744
مصطلحات موضوعية: Interleukin 2, animal structures, Janus kinase 1, T cell, Janus kinase 3, food and beverages, Cell Biology, Biology, Biochemistry, Molecular biology, medicine.anatomical_structure, Complementary DNA, medicine, Receptor, Cytokine receptor, Molecular Biology, Tyrosine kinase, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::7f08fc016cdb523d5b4de102359f4dff
https://doi.org/10.1074/jbc.271.18.10738 -
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المؤلفون: Maria Pasztoi, Neil Smyth, Dóra Haluszka, Susan D. John, Sarolta Kárpáti, Eszter Ostorházi, Edit I. Buzás, Mats Paulsson, Norbert Wikonkál, Ilona Németh, Péter Bognár, Balázs Mayer, Erzsébet Temesvári, Robert Szipocs, Attila Kolonics
المصدر: The Journal of investigative dermatology. 134(1)
مصطلحات موضوعية: Male, Pathology, medicine.medical_specialty, Tissue transglutaminase, Inflammation, Dermatology, Dermatitis, Contact, Biochemistry, Mice, Immune system, In vivo, medicine, Animals, Edema, Propionibacterium acnes, Molecular Biology, Barrier function, Sensitization, Gram-Positive Bacterial Infections, Skin, Mice, Knockout, Transglutaminases, biology, Cell Biology, Immunoglobulin E, Flow Cytometry, Mice, Inbred C57BL, medicine.anatomical_structure, Knockout mouse, biology.protein, Female, Lymph, Lymph Nodes, medicine.symptom, Fluorescein-5-isothiocyanate
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المؤلفون: Manuela Bechtel, Mats Paulsson, Susan D. John, Sally Rosser-Davies, Roswitha Nischt, Sharada Mokkapati, Lars Thiebach, Neil Smyth, Christian Frie
المصدر: PLoS ONE, Vol 7, Iss 4, p e34252 (2012)
PLoS ONEمصطلحات موضوعية: Skin Physiology, Male, Anatomy and Physiology, Mouse, Tissue transglutaminase, Fluorescent Antibody Technique, lcsh:Medicine, Matrix (biology), Biochemistry, Cornea, Mice, 0302 clinical medicine, Keratin, Molecular Cell Biology, lcsh:Science, Barrier function, Skin, chemistry.chemical_classification, Mice, Knockout, 0303 health sciences, Multidisciplinary, biology, integumentary system, Genetically Modified Organisms, Cell Differentiation, Animal Models, Cell biology, Enzymes, medicine.anatomical_structure, Phenotype, 030220 oncology & carcinogenesis, Medicine, Female, Genetic Engineering, Hair Follicle, Research Article, Biotechnology, Immunoblotting, Dermatology, Hair and Nail Diseases, 03 medical and health sciences, Model Organisms, Microscopy, Electron, Transmission, medicine, Genetics, Animals, Biology, 030304 developmental biology, Cuticle (hair), Wound Healing, Transglutaminases, Epidermis (botany), lcsh:R, Hair follicle, Mice, Inbred C57BL, chemistry, Epidermal Cells, Immunology, biology.protein, Microscopy, Electron, Scanning, lcsh:Q, Gene Function, Epidermis, Wound healing, Animal Genetics, Developmental Biology
وصف الملف: text
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المؤلفون: Gordon L. Hager, J Mellentin-Michelotti, Susan D. John, William D. Pennie, Trevor Williams
المصدر: Journal of Biological Chemistry. 269:31983-31990
مصطلحات موضوعية: Expression vector, biology, Mouse mammary tumor virus, Mutagenesis (molecular biology technique), Enhancer RNAs, Cell Biology, biology.organism_classification, Biochemistry, Molecular biology, Long terminal repeat, Retrovirus, Enhancer, Molecular Biology, Transcription factor
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::eb2c9f296f5e7ad72a5022b1d946ebb0
https://doi.org/10.1016/s0021-9258(18)31792-7 -
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المؤلفون: Joost Schalkwijk, Ivonne M.J.J. van Vlijmen-Willems, Diana Rodijk-Olthuis, Ikuko Hara-Nishimura, Wiljan Hendriks, Neil Smyth, Kiyotaka Hitomi, Tsing Cheng, Susan D. John, Thomas Reinheckel, Patrick L.J.M. Zeeuwen
المصدر: The Faseb Journal, 24, 10, pp. 3744-55
The Faseb Journal, 24, 3744-55مصطلحات موضوعية: Chemical and physical biology [NCMLS 7], Cathepsin L, Blotting, Western, Cathepsin D, Fluorescent Antibody Technique, Scarring alopecia, Neuroinformatics [DCN 3], Legumain, Biochemistry, Polymerase Chain Reaction, Cornea, Mice, Genetics, medicine, Animals, Homeostasis, Molecular Biology, Tissue homeostasis, Corneal epithelium, DNA Primers, Cathepsin, Mice, Knockout, biology, Base Sequence, Cystatin M, medicine.disease, Molecular biology, Mice, Inbred C57BL, Cysteine Endopeptidases, medicine.anatomical_structure, biology.protein, Epidermis, Infection and autoimmunity [NCMLS 1], Biotechnology, Hair
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