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1Reduced replication fork speed promotes pancreatic endocrine differentiation and controls graft size
المؤلفون: Yuan Xing, Jinrang Kim, Lina Sui, Michael V. Zuccaro, Yurong Xin, Sandra Kleiner, Jose Oberholzer, Fabrizio Barbetti, Yi He, Leena Haataja, Danielle Baum, Daniela Georgieva, Jiayu Fu, Giacomo Diedenhofen, Qian Du, Dieter Egli, Yong Wang, Robin Goland, Peter Arvan, Qi Su
المصدر: JCI Insight, Vol 6, Iss 5 (2021)
JCI Insightمصطلحات موضوعية: 0301 basic medicine, DNA Replication, Pluripotent Stem Cells, Cell biology, medicine.medical_treatment, Induced Pluripotent Stem Cells, Transplants, Enteroendocrine cell, Stem cells, Biology, 03 medical and health sciences, Islets of Langerhans, Mice, 0302 clinical medicine, Settore MED/13, Aphidicolin, Insulin-Secreting Cells, medicine, Diabetes Mellitus, Endocrine system, Animals, Humans, Insulin, Progenitor cell, Induced pluripotent stem cell, Pancreas, Cell Proliferation, Cell Cycle, DNA replication, Beta cells, Stem cell transplantation, Cell Differentiation, General Medicine, Cell cycle, 030104 developmental biology, 030220 oncology & carcinogenesis, Medicine, Stem cell, Research Article
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ede0353ff77d1f6451f2fec056fda90
https://doaj.org/article/e40875517d8941f9a40856ae37cd467f -
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المؤلفون: Richard Chen, Stella Tran, Yong Wang, Matthias Hebrok, Mei-Lan Li, Anil Bhushan, Jose Oberholzer, Gopika G. Nair, Yuan Xing, Vinh Son Nguyen, Michael S Saxton, Simone Giacometti, Holger A. Russ, Gregory L. Szot, Jennifer S. Liu, Sapna Puri, Charity Juang
المصدر: Nature Cell Biology. 21:263-274
مصطلحات موضوعية: 0303 health sciences, Cellular differentiation, Enteroendocrine cell, Endogeny, Cell Biology, Biology, Embryonic stem cell, In vitro, Cell biology, Transplantation, 03 medical and health sciences, 0302 clinical medicine, Cell culture, 030220 oncology & carcinogenesis, Stem cell, 030304 developmental biology
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المؤلفون: Michael A. Bukys, Jose Oberholzer, Katie Sears, Krystal Finney, Yong Wang, Divya Trivedi, Alexander Mihas, Jan Jensen
المصدر: iScience
iScience, Vol 23, Iss 8, Pp 101346-(2020)مصطلحات موضوعية: 0301 basic medicine, Cell, Population, 02 engineering and technology, Experimental Models in Systems Biology, Biology, Regenerative medicine, Article, Multidisciplinary Design Optimization, 03 medical and health sciences, Directed differentiation, Stem Cells Research, medicine, lcsh:Science, education, education.field_of_study, Multidisciplinary, Systems Biology, Foregut, 021001 nanoscience & nanotechnology, Cell biology, 030104 developmental biology, medicine.anatomical_structure, lcsh:Q, Endoderm, 0210 nano-technology, Pancreas, Definitive endoderm
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4The Incremental Cost of Incompatible Living Donor Kidney Transplantation: A National Cohort Analysis
المؤلفون: Bashir R. Sankari, Marc P. Posner, Lloyd E. Ratner, Ron Shapiro, Jason R. Wellen, Adel Bozorgzadeh, David A. Gerber, Krista L. Lentine, A. Osama Gaber, Ty B. Dunn, Huiling Xiao, Debra L. Sudan, Christopher L. Marsh, George S. Lipkowitz, Jose Oberholzer, Marc L. Melcher, Xun Luo, John P. Roberts, Sandip Kapur, Matthew Cooper, Stanley C. Jordan, Jose M. El-Amm, Robert A. Montgomery, Jacqueline Garonzik-Wang, Pooja Singh, Dorry L. Segev, Ronald P. Pelletier, Babak J. Orandi, Mark A. Schnitzler, Michael A. Rees, Allan B. Massie, Paul W. Nelson, Mark D. Stegall, David A. Axelrod
المصدر: American Journal of Transplantation. 17:3123-3130
مصطلحات موضوعية: Graft Rejection, Male, Marginal cost, medicine.medical_specialty, 030232 urology & nephrology, 030230 surgery, Kidney Function Tests, Living donor, National cohort, 03 medical and health sciences, Postoperative Complications, 0302 clinical medicine, Risk Factors, Internal medicine, Living Donors, Humans, Immunology and Allergy, Medicine, Pharmacology (medical), health care economics and organizations, Kidney transplantation, Retrospective Studies, Transplantation, biology, business.industry, Flow cytometric crossmatch, Histocompatibility Testing, Graft Survival, Antibody titer, Middle Aged, Prognosis, medicine.disease, Kidney Transplantation, Surgery, Blood Group Incompatibility, Case-Control Studies, Quality of Life, biology.protein, Kidney Failure, Chronic, Female, Antibody, business, Follow-Up Studies, Glomerular Filtration Rate
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المؤلفون: Minglin Ma, Jose Oberholzer, Dale L. Greiner, Arturo J. Vegas, Nimit Dholakia, Michael Chen, Omid Veiseh, Raj Thakrar, Siddharth Jhunjhunwala, Stephanie Aresta-Dasilva, Jie Li, Alan Chiu, Sean M. Siebert, Katherine Tang, Andrew Bader, Robert Langer, Meirigeng Qi, Hok Hei Tam, Daniel G. Anderson, Atieh Sadraei, Erin Langan, Joshua C. Doloff, Marissa Griffin, Shady Farah, Matthew J. Webber
المصدر: Nature Materials. 20:1038-1038
مصطلحات موضوعية: Colony stimulating factor 1 receptor, Mechanics of Materials, Mechanical Engineering, Component (UML), medicine, Biomaterial, General Materials Science, General Chemistry, Foreign body, Biology, Condensed Matter Physics, medicine.disease, Neuroscience
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المؤلفون: Enza Marchese, James J. McGarrigle, Jose Oberholzer, Jin Wuk Lee, Yuan Xing, Matthew A. Bochenek, Mohammad Nourmohammadzadeh, David T. Eddington, Yong Wang, Yeh Chun-Chieh, Joshua E. Mendoza-Elias
المصدر: Lab on a Chip. 16:1466-1472
مصطلحات موضوعية: endocrine system, endocrine system diseases, Cell Survival, Microfluidics, Biomedical Engineering, Bioengineering, 02 engineering and technology, Biology, Hydrodynamic trapping, 01 natural sciences, Biochemistry, Article, Islets of Langerhans, Mice, Live cell imaging, Lab-On-A-Chip Devices, medicine, Animals, Humans, Cell survival, geography, geography.geographical_feature_category, Pancreatic islets, 010401 analytical chemistry, General Chemistry, 021001 nanoscience & nanotechnology, Islet, Molecular Imaging, 0104 chemical sciences, medicine.anatomical_structure, Feasibility Studies, Spatiotemporal resolution, Molecular imaging, 0210 nano-technology, Biomedical engineering
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbbdf6d2c28febd00dbd107b5b2173df
https://doi.org/10.1039/c5lc01173f -
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المؤلفون: Frédéric Ris, Jose Oberholzer, Giatgen A. Spinas, Helen I. Joller-Jemelka, Nurit Kaiser, Marc Y. Donath, Pavel Sergeev, Kathrin Maedler, Philippe A. Halban
المساهمون: University of Zurich
المصدر: Journal of Clinical Investigation, Vol. 110, No 6 (2002) pp. 851-860
مصطلحات موضوعية: Male, 10265 Clinic for Endocrinology and Diabetology, Nitric Oxide Synthase Type II, Type 2 diabetes, 2700 General Medicine, Antioxidants, Nitric Oxide Synthase/genetics/metabolism, Cells, Cultured, ddc:616, General Medicine, Middle Aged, Islets of Langerhans/drug effects/ metabolism, medicine.anatomical_structure, Glucose/ metabolism/toxicity, Female, Beta cell, Hyperglycemia/metabolism, Corrigendum, Interleukin-1/genetics/ metabolism, Adult, medicine.medical_specialty, Proline, 610 Medicine & health, Biology, Article, Islets of Langerhans, Receptors, Interleukin-1/metabolism, Downregulation and upregulation, Thiocarbamates, Internal medicine, Diabetes mellitus, medicine, Animals, Humans, Beta (finance), Aged, Type 1 diabetes, Pancreatic islets, Receptors, Interleukin-1, Proline/ analogs & derivatives/pharmacology, medicine.disease, Diabetes Mellitus, Type 2/metabolism, Glucose, Endocrinology, Antioxidants/pharmacology, Diabetes Mellitus, Type 2, Apoptosis, Hyperglycemia, Thiocarbamates/pharmacology, Nitric Oxide Synthase, Gerbillinae, Interleukin-1
وصف الملف: jci-127-92172.pdf - application/pdf
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المؤلفون: Tom Eirik Mollnes, John D. Lambris, Igor Lacík, Bjørg Steinkjer, Anne Mari Rokstad, Terje Espevik, Ole-Lars Brekke, Hilde Fure, Jose Oberholzer, Caroline S. Gravastrand, Liv Ryan, Shamal Hamad
المصدر: Acta Biomaterialia
مصطلحات موضوعية: 0301 basic medicine, Male, Alginates, Lysine, Biomedical Engineering, Capsules, 030204 cardiovascular system & hematology, Antibodies, Monoclonal, Humanized, Biochemistry, Peptides, Cyclic, Fibrin, Article, Thromboplastin, Biomaterials, 03 medical and health sciences, Tissue factor, 0302 clinical medicine, Glucuronic Acid, Coagulation (water treatment), Humans, Cell encapsulation, Molecular Biology, Blood Coagulation, Whole blood, Plant Proteins, biology, Chemistry, Hexuronic Acids, General Medicine, Adhesion, Complement System Proteins, Molecular biology, Microspheres, Complement system, 030104 developmental biology, Factor XII, biology.protein, Biophysics, Female, Biotechnology
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المؤلفون: Ryan Viola, Alvin C. Powers, Megan Sykes, Jose Oberholzer, Bjarki Johannesson, Greg Poffenberger, Neil Phillips, Damian J. Williams, Dieter Egli, Yong Wang, Nichole Danzl, Sean R. Campbell, Xiaojuan Chen, Rudolph L. Leibel, Lina Sui, Yuan Xing
المصدر: Diabetes
مصطلحات موضوعية: 0301 basic medicine, KOSR, Blood Glucose, Male, medicine.medical_specialty, Maf Transcription Factors, Large, Endocrinology, Diabetes and Metabolism, Technological Advances, Embryoid body, Biology, Cell Line, 03 medical and health sciences, Immunocompromised Host, Mice, Internal medicine, Insulin-Secreting Cells, Internal Medicine, medicine, Animals, Humans, Insulin, Induced pluripotent stem cell, Cell potency, Embryonic Stem Cells, Homeodomain Proteins, Induced stem cells, Cell Differentiation, Flow Cytometry, Embryonic stem cell, Immunohistochemistry, Cell biology, 030104 developmental biology, Endocrinology, Diabetes Mellitus, Type 1, Glucose, Female, Stem cell, Adult stem cell
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a0ee66833225cd94787df39697908f9
https://pubmed.ncbi.nlm.nih.gov/28931519 -
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المؤلفون: Kjetil Formo, Gilles J. Guillemin, Rolf Lennart Larsson, Vijayaganapathy Vaithilingam, Jose Oberholzer, Enza Marchese, Gabriela Kolláriková, Bernard E. Tuch, Meirigeng Qi, Igor Lacík
المصدر: Tissue Engineering Part A. 20:324-334
مصطلحات موضوعية: Male, Alginates, Cell Survival, Islets of Langerhans Transplantation, Biomedical Engineering, Capsules, Bioengineering, Mice, SCID, Pharmacology, Biology, Biochemistry, Permeability, Biomaterials, Islets of Langerhans, Mice, chemistry.chemical_compound, Coated Materials, Biocompatible, Glucuronic Acid, In vivo, Cell Adhesion, medicine, Animals, Humans, Blood Coagulation, geography, geography.geographical_feature_category, Heparin, Hexuronic Acids, Pancreatic islets, Organ Preservation, Islet, Glucuronic acid, Fibrosis, In vitro, Rats, Transplantation, medicine.anatomical_structure, chemistry, Rats, Inbred Lew, biology.protein, Female, Biomedical engineering, Avidin, medicine.drug