-
1
المؤلفون: Roman Tremmel, Kathrin Klein, Saskia Biskup, Tim Scheurenbrand, Elke Schaeffeler, Ulrich M. Zanger, S. Fehr, Stefan Winter, Matthias Schwab, Florian Battke
المصدر: Human Genetics
مصطلحات موضوعية: Genetic Markers, congenital, hereditary, and neonatal diseases and abnormalities, endocrine system diseases, DNA Copy Number Variations, Computational biology, Biology, Correlation, 03 medical and health sciences, Exon, mental disorders, Exome Sequencing, Genetics, Humans, Copy-number variation, Exome, Gene, Genetics (clinical), 030304 developmental biology, Retrospective Studies, 0303 health sciences, 030305 genetics & heredity, Computational Biology, High-Throughput Nucleotide Sequencing, Human genetics, 3. Good health, Liver, Genetic marker, Pharmacogenetics, Pharmacogenomics
-
2
المؤلفون: Kathrin Klein, Roman Tremmel, Stefan Winter, Sarah Fehr, Florian Battke, Tim Scheurenbrand, Elke Schaeffeler, Saskia Biskup, Matthias Schwab, Ulrich M. Zanger
المصدر: Frontiers in Genetics
Frontiers in Genetics, Vol 10 (2019)مصطلحات موضوعية: lcsh:QH426-470, Biology, DNA sequencing, 03 medical and health sciences, 0302 clinical medicine, Genotype, Genetics, Coding region, Indel, Gene, Genetics (clinical), 030304 developmental biology, Original Research, next generation sequencing, pharmacogenomics, 0303 health sciences, Intron, rare variants, 3. Good health, Minor allele frequency, lcsh:Genetics, genomic DNA, ADME, eQTL analysis, 030220 oncology & carcinogenesis, Molecular Medicine
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86568e793f6c4b9717e85eadc291864e
http://europepmc.org/articles/PMC6365429 -
3
المؤلفون: Anca Florian, Alexandru Patrascu, Roman Tremmel, Sabine Rösch, Udo Sechtem, Matthias Schwab, Elke Schaeffeler, Ali Yilmaz
المصدر: Frontiers in Physiology, Vol 9 (2018)
Frontiers in Physiologyمصطلحات موضوعية: muscular dystrophy, medicine.medical_specialty, Physiology, Cardiomyopathy, 030204 cardiovascular system & hematology, lcsh:Physiology, 03 medical and health sciences, cardiovascular magnetic resonance, 0302 clinical medicine, Physiology (medical), Internal medicine, medicine, Muscular dystrophy, Myopathy, Original Research, medicine.diagnostic_test, biology, microRNA, lcsh:QP1-981, business.industry, Skeletal muscle, Magnetic resonance imaging, medicine.disease, female carriers, Circulating MicroRNA, medicine.anatomical_structure, Cardiology, biology.protein, Creatine kinase, medicine.symptom, business, cardiomyopathy, 030217 neurology & neurosurgery, Blood drawing
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78e188f9d3b35541945db771ec0e2c2e
https://www.frontiersin.org/article/10.3389/fphys.2018.01770/full -
4
المؤلفون: Ulrich M. Zanger, Roman Tremmel, Stefan Winter, Elke Schaeffeler, Kathrin Klein
المصدر: The Pharmacogenomics Journal. 16:551-558
مصطلحات موضوعية: 0301 basic medicine, DNA Copy Number Variations, Pharmacogenomic Variants, Gene Dosage, Biology, Hydroxylation, Polymerase Chain Reaction, Polymorphism, Single Nucleotide, Gene dosage, Gene Expression Regulation, Enzymologic, White People, Cell Line, 03 medical and health sciences, CYP2E1 Gene, Gene Duplication, Databases, Genetic, Gene duplication, Gene expression, Genetics, Humans, Copy-number variation, Oligonucleotide Array Sequence Analysis, Pharmacology, Regulation of gene expression, Microarray analysis techniques, Gene Expression Profiling, Cytochrome P-450 CYP2E1, Gene expression profiling, Chlorzoxazone, Phenotype, 030104 developmental biology, Haplotypes, Hepatocytes, Molecular Medicine, Gene Deletion
-
5
المصدر: Genome Medicine
Genome Medicine, Vol 9, Iss 1, Pp 1-15 (2017)مصطلحات موضوعية: 0301 basic medicine, Drug, Exome sequence analysis, Drug-Related Side Effects and Adverse Reactions, Pharmacogenomic Variants, lcsh:QH426-470, media_common.quotation_subject, Population, lcsh:Medicine, Biology, Bioinformatics, Efficacy, 03 medical and health sciences, 0302 clinical medicine, Bioinformatics analysis, Mutation Rate, Pharmacokinetics, Genetic variation, Genetics, Humans, Quantitative Biology - Genomics, Genetic variability, Adverse effect, education, Gene, Molecular Biology, Genetics (clinical), Exome sequencing, 030304 developmental biology, media_common, Genomics (q-bio.GN), 0303 health sciences, education.field_of_study, Genome, Human, Research, lcsh:R, Human genetics, 3. Good health, lcsh:Genetics, 030104 developmental biology, 030220 oncology & carcinogenesis, FOS: Biological sciences, Pharmacogenomics, Molecular Medicine
-
6
المؤلفون: Kathrin Klein, Jessica K. Rieger, Benjamin A. Kandel, Roman Tremmel, Ulrich M. Zanger, Tarek Magdy, M Klein, Maria Thomas
المصدر: Clinical Pharmacology & Therapeutics. 95:258-261
مصطلحات موضوعية: Epigenomics, Drug, Gene isoform, media_common.quotation_subject, Polymorphism, Single Nucleotide, Gene Expression Regulation, Enzymologic, Cytochrome P-450 Enzyme System, Biotransformation, Drug Discovery, Genetic variation, Genetics, Humans, Pharmacology (medical), Epigenetics, media_common, Pharmacology, Regulation of gene expression, chemistry.chemical_classification, biology, Genetic Variation, Cytochrome P450, Isoenzymes, Enzyme, chemistry, biology.protein
-
7
المؤلفون: Kathrin Klein, Matthias Schwab, Richard M. Weinshilboum, Reedik Mägi, Richard S. Houlston, Martin Schrappe, Irena Mlinarič Raščan, Elke Schaeffeler, Stefan Winter, Martin Stanulla, Evelin Mihailov, Lili Milani, Roman Tremmel, Andres Metspalu, Anja Möricke, Alenka Šmid, Riin Tamm
المصدر: Clinical Pharmacology & Therapeutics
مصطلحات موضوعية: 0301 basic medicine, Estonia, Genome-wide association study, Biology, Article, 03 medical and health sciences, Genetic variation, Genotype, medicine, Humans, Pharmacology (medical), Allele, Alleles, Genetic testing, Pharmacology, Genetics, Polymorphism, Genetic, medicine.diagnostic_test, Thiopurine methyltransferase, Methyltransferases, Mercaptopurine, 3. Good health, 030104 developmental biology, Phenotype, biology.protein, Pharmacogenetics, medicine.drug, Genome-Wide Association Study
-
8
المؤلفون: Stefano Landi, Rossella Elisei, Roman Tremmel, Elisa Barone, Gisella Figlioli, Eric L. Seiser, Chiara De Santi, Federica Gemignani, Ulrich M. Zanger, Cristina Romei, Federico Innocenti, Monica Cipollini, Ombretta Melaiu, Lucia Pellè
مصطلحات موضوعية: 0301 basic medicine, Male, Linkage disequilibrium, Health, Toxicology and Mutagenesis, Case-control association study, Thyroid Gland, Case–control association study, Toxicology, Cytochrome P450 2E1, Linkage Disequilibrium, Cohort Studies, Hospitals, University, 0302 clinical medicine, Genotype, 3' Untranslated Regions, Sequence Tagged Sites, Genetics, Settore BIO/18, Cell Differentiation, Cytochrome P-450 CYP2E1, General Medicine, Middle Aged, Italy, Health, 030220 oncology & carcinogenesis, Differentiated thyroid carcinoma, Female, Adult, medicine.medical_specialty, Single-nucleotide polymorphism, Biology, Polymorphism, Single Nucleotide, Thyroid carcinoma, 03 medical and health sciences, Internal medicine, medicine, Genetic predisposition, Genetic susceptibility, Humans, Genetic Predisposition to Disease, Toxicology and Mutagenesis, RNA, Messenger, Thyroid Neoplasms, Genetic Association Studies, Haplotype, Carcinoma, Case-control study, Polymorphisms, Introns, Minor allele frequency, 030104 developmental biology, Endocrinology, Case-Control Studies
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ad023f79ee5eca5e7757d1d6f480df0
http://hdl.handle.net/2108/305972 -
9
المؤلفون: Matthias Schwab, Elke Schaeffeler, Saskia Biskup, Ulrich M. Zanger, Kathrin Klein, S. Fehr, Stefan Winter, Roman Tremmel
المصدر: Drug Metabolism and Pharmacokinetics. 32:S88
مصطلحات موضوعية: Pharmacology, Genetics, Human liver, Pharmaceutical Science, Pharmacology (medical), Biology, Gene, ADME
-
10
المؤلفون: Fabian Schumacher, Hansruedi Glatt, Monika Schreiner, Walter Meinl, Benjamin Sachse, Wolfram Engst, Achim Bub, C. Bendadani, Kristin Herrmann, Roman Tremmel, M. Bernau, Gitte Barknowitz, Melanie Wiesner, Ulrich M. Zanger, Bernhard H. Monien
المصدر: Toxicology Letters. 238:S33
مصطلحات موضوعية: Human blood, Scientific method, Environmental chemistry, General Medicine, Biology, Toxicology, Carcinogen, Macromolecule, Adduct