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المؤلفون: Radislav Sedlacek, Nay Chi Khin, Yo-ichi Nabeshima, Ruby Dawson, Andrew W. Trafford, Paul Q. Thomas, Mizuho Iwama, Gaetan Burgio, Tomoji Mashimo, Neil E. Humphreys, Anne Harrington, Xuesong Zhang, John H. Adams, E. Jonasch, Benjamin Morpurgo, Mariette Ouellet, James D. Eudy, Leen Vanhoutte, David W. Ray, Bernard Keavney, Kenichi Nakashima, Pilar Alcaide, Shiho Imai, Masato Ohtsuka, Tomohiro Tanaka, Xin Yi, Petr Kasparek, Ane M. Salvador, Nikki Ross, Moorthy P. Ponnusamy, Victoria E. DeMambro, Yoshiki Miyasaka, Ilka Pinz, Koji Nakade, Leif Oxburgh, Lin Li, Jenna Lowe, Frederique Vanrockeghem, Katherine J. Motyl, Tino Hochepied, Clifford J. Rosen, Jan Parker-Thornburg, Guillaume Bernas, Christian S. Wright, Lucy Liaw, Huiping Guo, Amy Gonzales, Yuichi Obata, Kathleen A. Becker, Antony Adamson, Channabasavaiah B. Gurumurthy, David Brough, Satoru Takahashi, Fumihiro Sugiyama, Joseph M. Miano, William R. Thompson, Lin Gan, Hideshi Ishii, Jing Gao, Kevin C K Lloyd, Hao Zhu, Daniel J. Garry, Imayavaramban Lakshmanan, Sandra Piltz, Rolen M. Quadros, Satyabrata Das, Joshua A. Wood, Aidan R. O’Brien, Catherine B. Lawrence, Michelle Karolak, Karan Sharma, Mark T. Ruhe, Sabrina Shameen Alam, Katrien Staes, Lora Starrs, Andrew S. I. Loudon, Yoshihiro Uno, Seiya Mizuno, Mitra Cowan, Taiji Matsusaka, Yuko Yamauchi, Chad Smith, Andrei Golovko, Brandon J. Willis, Larisa Ryzhova, Catherine Larochelle, Hiromi Miura, Atsushi Yoshiki, Kathryn E. Hentges, Loydie Jerome-Majeweska, Wesley Chan, Ronald Redder, Toshiaki Nakashiba, Johnathan Ballard, Jinke D’Hont, Marie-Claude Beauchamp, Katharine M. Dibb, Kazuto Yoshimi, Donald W. Harms, Volkhard Lindner, Shinya Ayabe, Surinder K. Batra, Francisco J. Carrillo-Salinas, Gloria Lopez-Castejon, Yuko Kotani, Xian De Liu, Hanying Chen, Yu Zhang, Anyonya R. Guntur, Sanae Ogiwara, Yayoi Kunihiro, Masamitsu Konno, Jean Francois Schmouth
المصدر: Genome Biology, Vol 22, Iss 1, Pp 1-4 (2021)
Genome Biology
GENOME BIOLOGYمصطلحات موضوعية: Gene Editing, lcsh:QH426-470, Biology and Life Sciences, Reproducibility of Results, Computational biology, Biology, Human genetics, lcsh:Genetics, Mice, lcsh:Biology (General), CRISPR-Associated Protein 9, Correspondence, CRISPR, Animals, Center (algebra and category theory), Allele, CRISPR-Cas Systems, lcsh:QH301-705.5, Alleles
وصف الملف: application/pdf
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المؤلفون: Sevane Mugisha, Rachel Aber, Loydie A. Jerome-Majewska, Wesley Chan
المصدر: Genetics Research
مصطلحات موضوعية: Mutant, Morphogenesis, Vesicular Transport Proteins, macromolecular substances, Review, Biology, Cell fate determination, 03 medical and health sciences, 0302 clinical medicine, Genetics, Animals, Humans, TMED, Receptor, Transport Vesicles, development, Secretory pathway, 030304 developmental biology, 0303 health sciences, disease, Membrane Proteins, General Medicine, Intracellular Membranes, p24, Phenotype, Transmembrane protein, Cell biology, Transport protein, Protein Transport, 030220 oncology & carcinogenesis, cargo receptor, Carrier Proteins
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المصدر: The American Journal of Pathology. 188:160-172
مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, genetic structures, Cell Survival, Biology, Cobalamin, Retinal ganglion, Neuroprotection, Article, Pathology and Forensic Medicine, Optic neuropathy, Superoxide dismutase, 03 medical and health sciences, chemistry.chemical_compound, Menadione, Superoxides, Internal medicine, Optic Nerve Diseases, polycyclic compounds, medicine, Animals, Rats, Long-Evans, Neurons, Superoxide, Vitamin K 3, nutritional and metabolic diseases, Vitamin B 12 Deficiency, medicine.disease, eye diseases, Rats, 3. Good health, Vitamin B 12, Neuroprotective Agents, 030104 developmental biology, Endocrinology, chemistry, Biochemistry, biology.protein, Optic nerve, Female, sense organs
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المؤلفون: Shruti Kumar, Sabrina Shameen Alam, Lodyie Jerome‐Majewska, Marie-Claude Beauchamp, Wesley Chan
المصدر: The FASEB Journal. 33
مصطلحات موضوعية: 0303 health sciences, 03 medical and health sciences, 0302 clinical medicine, Expression pattern, Embryogenesis, Genetics, Biology, Molecular Biology, Biochemistry, 030217 neurology & neurosurgery, 030304 developmental biology, Biotechnology, Cell biology
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المؤلفون: Maya U. Sheth, So Young Kim, Mohit Kumar Jolly, Sneha Rao, Shengnan Xu, Andrew J. Armstrong, Jason A. Somarelli, William C. Eward, Wesley Chan, Kathryn E. Ware, Yuantong Ding
المصدر: Journal of Clinical Medicine; Volume 8; Issue 2; Pages: 205
Journal of Clinical Medicine
Journal of Clinical Medicine, Vol 8, Iss 2, p 205 (2019)مصطلحات موضوعية: 0301 basic medicine, autophagy, Systems biology, evolution, systems biology, lung cancer, epithelial–mesenchymal transition, tumor invasiveness, metabolism, lcsh:Medicine, Computational biology, Biology, Article, 03 medical and health sciences, 0302 clinical medicine, Phylogenetics, Medicine, Epithelial–mesenchymal transition, ATG16L1, Tumor microenvironment, Gene knockdown, business.industry, Mechanism (biology), Autophagy, lcsh:R, Cancer, General Medicine, medicine.disease, 030104 developmental biology, 030220 oncology & carcinogenesis, business
وصف الملف: application/pdf
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المؤلفون: Antony Adamson, Ane M. Salvador, Pilar Alcaide, Joseph M. Miano, Gaetan Burgio, Satoru Takahashi, David Brough, Bernard Keavney, Anne Harrington, Surinder K. Batra, Francisco J. Carrillo-Salinas, Lucy Liaw, Kathryn E. Hentges, Imayavaramban Lakshmanan, Fumihiro Sugiyama, Seiya Mizuno, Catherine B. Lawrence, Yuichi Obata, Karan Sharma, Kevin C K Lloyd, Mariette Ouellet, Andrew S. I. Loudon, Nay Chi Khin, Yo-ichi Nabeshima, Xin Yi, Masato Ohtsuka, Huiping Guo, Channabasavaiah B. Gurumurthy, Yoshihiro Uno, William R. Thompson, Hanying Chen, Jinke D’Hont, Daniel J. Garry, Sandra Piltz, Lora Starrs, Clifford J. Rosen, Benjamin Morpurgo, Yuko Yamauchi, Nikki Ross, Aidan R. O’Brien, Yuko Kotani, Chad Smith, Tino Hochepied, Loydie A. Jerome-Majewska, Koji Nakade, Ilka Pinz, James D. Eudy, Amy Gonzales, Paul Q. Thomas, Wesley Chan, Leif Oxburgh, Leen Vanhoutte, Mitra Cowan, Radislav Sedlacek, Donald W. Harms, Volkhard Lindner, Marie-Claude Beauchamp, Tomoji Mashimo, Larisa Ryzhova, Jenna Lowe, Joshua A. Wood, Brandon J. Willis, Jan Parker-Thornburg, Gloria Lopez-Castejon, Victoria E. DeMambro, Ronald Redder, Shinya Ayabe, Mizuho Iwama, Satyabrata Das, Ruby Dawson, Tomohiro Tanaka, Toshiaki Nakashiba, Eric Jonasch, Andrew W. Trafford, Hiromi Miura, Hao Zhu, Yu Zhang, Guillaume Bernas, Kazuto Yoshimi, Neil E. Humphreys, John H. Adams, Kathleen A. Becker, Petr Kasparek, Yoshiki Miyasaka, Anyonya R. Guntur, Hideshi Ishii, Sabrina Shameen Alam, Katrien Staes, Lin Li, Shiho Imai, Katherine J. Motyl, Kenichi Nakashima, Katharine M. Dibb, Johnathan Ballard, Frederique Vanrockeghem, Mark T. Ruhe, Jing Gao, Christian S. Wright, Xian De Liu, Andrei Golovko, Rolen M. Quadros, David W. Ray, Atsushi Yoshiki, Catherine Larochelle, Masamitsu Konno, Lin Gan, Michelle Karolak, Jean Francois Schmouth, Xuesong Zhang, Taiji Matsusaka, Yayoi Kunihiro, Sanae Ogiwara, Moorthy P. Ponnusamy
المصدر: GENOME BIOLOGY
Genome Biology, Vol 20, Iss 1, Pp 1-14 (2019)
Gurumurthy, C B, O'Brien, A R, Quadros, R M, Adams, J, Alcaide, P, Ayabe, S, Ballard, J, Batra, S K, Beauchamp, M-C, Becker, K A, Bernas, G, Brough, D, Carrillo-Salinas, F, Chan, W, Chen, H, Dawson, R, Demambro, V, D'Hont, J, Dibb, K M, Eudy, J D, Gan, L, Gao, J, Gonzales, A, Guntur, A R, Guo, H, Harms, D W, Harrington, A, Hentges, K E, Humphreys, N, Imai, S, Ishii, H, Iwama, M, Jonasch, E, Karolak, M, Keavney, B, Khin, N-C, Konno, M, Kotani, Y, Kunihiro, Y, Lakshmanan, I, Larochelle, C, Lawrence, C B, Li, L, Lindner, V, Liu, X-D, Lopez-Castejon, G, Loudon, A, Lowe, J, Jerome-Majewska, L A, Matsusaka, T, Miura, H, Miyasaka, Y, Morpurgo, B, Motyl, K, Nabeshima, Y-I, Nakade, K, Nakashiba, T, Nakashima, K, Obata, Y, Ogiwara, S, Ouellet, M, Oxburgh, L, Piltz, S, Pinz, I, Ponnusamy, M P, Ray, D, Redder, R J, Rosen, C J, Ross, N, Ruhe, M T, Ryzhova, L, Salvador, A M, Alam, S S, Sedlacek, R, Sharma, K, Smith, C, Staes, K, Starrs, L, Sugiyama, F, Takahashi, S, Tanaka, T, Trafford, A W, Uno, Y, Vanhoutte, L, Vanrockeghem, F, Willis, B J, Wright, C S, Yamauchi, Y, Yi, X, Yoshimi, K, Zhang, X, Zhang, Y, Ohtsuka, M, Das, S, Garry, D J, Hochepied, T, Thomas, P, Parker-Thornburg, J, Adamson, A D, Yoshiki, A, Schmouth, J-F, Golovko, A, Thompson, W R, Lloyd, K C K, Wood, J A, Cowan, M, Mashimo, T, Mizuno, S, Zhu, H, Kasparek, P, Liaw, L, Miano, J M & Burgio, G 2019, ' Reproducibility of CRISPR-Cas9 methods for generation of conditional mouse alleles: a multi-center evaluation ', Genome biology, vol. 20, no. 1, 171 . https://doi.org/10.1186/s13059-019-1776-2, https://doi.org/10.1186/s13059-019-1776-2
Genome Biologyمصطلحات موضوعية: Male, ResearchInstitutes_Networks_Beacons/global_development_institute, Mouse, Methyl-CpG-Binding Protein 2, EFFICIENT, 0302 clinical medicine, CRISPR-Associated Protein 9, Oligonucleotide, Conditional gene knockout, Medicine and Health Sciences, CRISPR, MODIFIED MICE, Guide RNA, lcsh:QH301-705.5, Conditional, Mice, Knockout, 0303 health sciences, EMBRYO, Conditional knockout mouse, Reproducibility, ONE-STEP GENERATION, Regression Analysis, Female, ELECTROPORATION, Transgenesis, CRISPR-Cas9, INTEGRATION, Homology-directed repair, Microinjections, lcsh:QH426-470, INSERTION, Mutagenesis (molecular biology technique), Computational biology, Biology, Homology directed repair, 03 medical and health sciences, National Graphene Institute, Machine learning, Animals, Allele, CRISPR/CAS9, Floxing, Alleles, 030304 developmental biology, MUTAGENESIS, Research, Floxed allele, Reproducibility of Results, Biology and Life Sciences, DNA, Long single-stranded DNA, Long single-stranded, Human genetics, lcsh:Genetics, Blastocyst, Global Development Institute, KNOCKOUT, lcsh:Biology (General), ResearchInstitutes_Networks_Beacons/national_graphene_institute, CRISPR-Cas Systems, Factor Analysis, Statistical, knockout mouse, 030217 neurology & neurosurgery
وصف الملف: application/pdf
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المصدر: Experimental Eye Research. 97:31-35
مصطلحات موضوعية: Retinal Ganglion Cells, Programmed cell death, genetic structures, Cell Survival, Metalloporphyrins, medicine.medical_treatment, Apoptosis, Article, Superoxide dismutase, 03 medical and health sciences, Cellular and Molecular Neuroscience, chemistry.chemical_compound, 0302 clinical medicine, Coordination Complexes, Superoxides, Optic Nerve Diseases, medicine, Animals, Superoxide dismutase mimetics, Rats, Long-Evans, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, Reactive oxygen species, Microscopy, Confocal, biology, Superoxide, Axotomy, Free Radical Scavengers, Axons, eye diseases, Sensory Systems, Rats, Cell biology, Ophthalmology, Neuroprotective Agents, medicine.anatomical_structure, chemistry, Retinal ganglion cell, Optic Nerve Injuries, Intravitreal Injections, Optic nerve, biology.protein, Female, sense organs, Neuroscience, 030217 neurology & neurosurgery, Signal Transduction
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