يعرض 1 - 10 نتائج من 423 نتيجة بحث عن '"Mechanisms of Action: Physiological Effects"', وقت الاستعلام: 1.57s تنقيح النتائج
  1. 1
    Mitochondria as a Potential Target for the Development of Prophylactic and Therapeutic Drugs against Schistosoma mansoni Infection

    المؤلفون: Naotoshi Tsuji, Takeshi Hatta, Hiroyuki Saimoto, Minoru Wada, Daniel Ken Inaoka, Kiyoshi Kita, Keith Kiplangat Talaam, Daigo Tsubokawa, Shinjiro Hamano

    المصدر: Antimicrob Agents Chemother

    مصطلحات موضوعية: Schistosomiasis, Pharmacology, Biology, Mice, Schistosomicides, chemistry.chemical_compound, parasitic diseases, medicine, Animals, Pharmacology (medical), Mechanisms of Action: Physiological Effects, Mefloquine, Nitazoxanide, Schistosoma mansoni, medicine.disease, biology.organism_classification, Schistosomiasis mansoni, Mitochondria, Praziquantel, Infectious Diseases, Pharmaceutical Preparations, Ascofuranone, chemistry, Ex vivo, Atovaquone, medicine.drug

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::202cb12c5eade08dcd2b4b38f987cac3
    https://doi.org/10.1128/aac.00418-21

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  2. 2
    The Novel bis-1,2,4-Triazine MIPS-0004373 Demonstrates Rapid and Potent Activity against All Blood Stages of the Malaria Parasite

    المؤلفون: Madeline R. Luth, Fernando Sánchez-Román Terán, Jake Baum, Ursula Straschil, Michael D. Edstein, Michael J. Delves, Leonardo Lucantoni, Elizabeth A. Winzeler, Stuart A. Ralph, Katherine M. Ellis, Marina Chavchich, Jonathan B. Baell, Darren J. Creek, Clemens H. M. Kocken, Amanda De Paoli, Vicky M. Avery, Anne-Marie Zeeman, Matthew Abraham

    المصدر: Antimicrob Agents Chemother

    مصطلحات موضوعية: Male, Plasmodium berghei, Biology, Pharmacology, 03 medical and health sciences, chemistry.chemical_compound, Chloroquine, In vivo, parasitic diseases, Gametocyte, medicine, Animals, Pharmacology (medical), Parasites, Mechanisms of Action: Physiological Effects, 030304 developmental biology, 0303 health sciences, 030306 microbiology, Triazines, Plasmodium falciparum, biology.organism_classification, medicine.disease, In vitro, 3. Good health, Malaria, Infectious Diseases, chemistry, Artesunate, medicine.drug

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0488fc3eba297e566a5bcc209793de5
    https://pubmed.ncbi.nlm.nih.gov/34460304

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  3. 3
    Synergistic Action between PfHsp90 Inhibitor and PfRad51 Inhibitor Induces Elevated DNA Damage Sensitivity in the Malaria Parasite

    المؤلفون: Priyanka Singh, Niranjan Suthram, Wahida Tabassum, Sunanda Bhattacharyya, Mrinal Kanti Bhattacharyya

    المصدر: Antimicrob Agents Chemother

    مصطلحات موضوعية: DNA repair, DNA damage, Plasmodium falciparum, RAD51, 03 medical and health sciences, chemistry.chemical_compound, Recombinase, Animals, Humans, Parasites, Pharmacology (medical), Malaria, Falciparum, Mechanisms of Action: Physiological Effects, 030304 developmental biology, Pharmacology, 0303 health sciences, biology, 030306 microbiology, biology.organism_classification, Molecular biology, Malaria, Methyl methanesulfonate, Infectious Diseases, chemistry, Homologous recombination, DNA, DNA Damage

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2471ed98bbf375d1cbcca4a7dd60d156
    https://doi.org/10.1128/aac.00457-21

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  4. 4
    Piperidine-4-Carboxamides Target DNA Gyrase in Mycobacterium abscessus

    المؤلفون: Nadine Alvarez, Véronique Dartois, Thomas Dick, Dereje Abate Negatu, Peter Imming, Martin Gengenbacher, Benoît Laleu, Matthew D. Zimmerman, Andreas Beuchel, Wassihun Wedajo Aragaw, Abdeldjalil Madani, Chao Chen

    المصدر: Antimicrobial Agents and Chemotherapy

    مصطلحات موضوعية: nontuberculous mycobacteria, 0301 basic medicine, DNA damage, 030106 microbiology, Mycobacterium Infections, Nontuberculous, Microbial Sensitivity Tests, Mycobacterium abscessus, DNA gyrase, Microbiology, law.invention, Mycobacterium tuberculosis, 03 medical and health sciences, chemistry.chemical_compound, Piperidines, law, Humans, Pharmacology (medical), Mechanisms of Action: Physiological Effects, Pharmacology, biology, bacterial infections and mycoses, biology.organism_classification, Anti-Bacterial Agents, Multiple drug resistance, 030104 developmental biology, Infectious Diseases, chemistry, DNA Gyrase, Recombinant DNA, bacteria, Nontuberculous mycobacteria, NTM, DNA, MMV688844

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69c69f70c24af25e0f7fea7baac12643
    https://doi.org/10.1128/aac.00676-21

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  5. 5
    Ethylzingerone, a Novel Compound with Antifungal Activity

    المؤلفون: Rosemary Ann Barnes, Laurence Decourty, Sylvie Cupferman, Florence Menard-Szczebara, Christophe d'Enfert, Cosmin Saveanu, Maria Dalko-Sciba, Jean-Yves Maillard, Sadri Znaidi, Rebecca Wesgate, Murielle Chauvel, Tristan Rossignol

    المساهمون: Biologie et Pathogénicité fongiques, Institut Pasteur [Paris]-Institut National de la Recherche Agronomique (INRA), Laboratoire de Microbiologie Moléculaire, Vaccinologie et Développement Biotechnologique (LR11IPT01), Institut Pasteur de Tunis, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), Cardiff University, Génétique des Interactions macromoléculaires, Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), L’Oréal Research and Innovation, University Hospital of Wales [Cardiff, UK], Cardiff University (Cardiff University), L'Oreal Group, L'Oreal, France, ANR-10-LABX-0062,IBEID,Integrative Biology of Emerging Infectious Diseases(2010), ANR-08-JCJC-0019,GENO-GIM,Obtention d'une carte d'interactions génétiques à l'échelle génomique chez la levure(2008), Biologie et Pathogénicité fongiques (BPF), Institut National de la Recherche Agronomique (INRA)-Institut Pasteur [Paris] (IP), Génétique des Interactions macromoléculaires / Genetics of Macromolecular Interactions, Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), University Hospital of Wales (UHW)

    المصدر: Antimicrobial Agents and Chemotherapy
    Antimicrobial Agents and Chemotherapy, American Society for Microbiology, 2021, 65 (4), pp.e02711-20. ⟨10.1128/AAC.02711-20⟩
    Antimicrobial Agents and Chemotherapy, 2021, 65 (4), pp.e02711-20. ⟨10.1128/AAC.02711-20⟩
    Antimicrob Agents Chemother

    مصطلحات موضوعية: Antifungal Agents, [SDV]Life Sciences [q-bio], Saccharomyces cerevisiae, HEPB, Microbiology, ethylzingerone, 03 medical and health sciences, chemistry.chemical_compound, hydroxyethoxyphenyl butanone, Candida albicans, Aromatic amino acids, Pharmacology (medical), Mechanisms of Action: Physiological Effects, [SDV.MP.MYC]Life Sciences [q-bio]/Microbiology and Parasitology/Mycology, Amino acid synthesis, 030304 developmental biology, Pharmacology, chemistry.chemical_classification, 0303 health sciences, Candida glabrata, biology, cosmetics, 030306 microbiology, Antimicrobial, biology.organism_classification, Corpus albicans, 3. Good health, Triclosan, Infectious Diseases, chemistry, [SDV.SP.PHARMA]Life Sciences [q-bio]/Pharmaceutical sciences/Pharmacology, antifungal, mechanism of action

    وصف الملف: application/pdf

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54439dfb6770535420f9c85f63aa771c
    https://doi.org/10.1128/aac.02711-20

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  6. 6
    Efg1 and Cas5 Orchestrate Cell Wall Damage Response to Caspofungin in Candida albicans

    المؤلفون: Chang Su, Kang Xiong, Qiangqiang Sun, Yang Lu

    المصدر: Antimicrob Agents Chemother

    مصطلحات موضوعية: Antifungal Agents, Fungal Proteins, Echinocandins, Lipopeptides, 03 medical and health sciences, chemistry.chemical_compound, Caspofungin, Cell Wall, Gene Expression Regulation, Fungal, Candida albicans, Gene expression, polycyclic compounds, medicine, Transcriptional regulation, Humans, Pharmacology (medical), skin and connective tissue diseases, Mechanisms of Action: Physiological Effects, Transcription factor, 030304 developmental biology, Pharmacology, 0303 health sciences, biology, 030306 microbiology, Candidiasis, Promoter, bacterial infections and mycoses, biology.organism_classification, medicine.disease, Cell biology, Infectious Diseases, chemistry, Systemic candidiasis

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa9bc3a52d84d59d7d1af0cd3c96b79a
    https://doi.org/10.1128/aac.01584-20

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  7. 7
    Perillyl alcohol reduces parasite sequestration and cerebrovascular dysfunction during experimental cerebral malaria

    المؤلفون: Daniella S. Battagello, Alejandro M. Katzin, Jackson C. Bittencourt, Luana dos Santos Ortolan, Adriana A Marin, Thatyane de Castro Quirino, Sabrina Epiphanio, Leonardo J M Carvalho, Rodrigo A.C. Sussmann, Oscar Murillo

    المصدر: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
    Universidade de São Paulo (USP)
    instacron:USP
    Antimicrob Agents Chemother

    مصطلحات موضوعية: MACRÓFAGOS, CD36, Pharmacology, Blood–brain barrier, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, In vivo, parasitic diseases, medicine, Pharmacology (medical), Plasmodium berghei, Mechanisms of Action: Physiological Effects, 030304 developmental biology, 0303 health sciences, biology, business.industry, Perillyl alcohol, Human brain, biology.organism_classification, Endothelial stem cell, Infectious Diseases, medicine.anatomical_structure, chemistry, Cerebral Malaria, 030220 oncology & carcinogenesis, biology.protein, business

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70a3bab798bf9b58af30e917c095cc89

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  8. 8
    Metabolic Survival Adaptations of Plasmodium falciparum Exposed to Sublethal Doses of Fosmidomycin

    المؤلفون: Russell P. Swift, Jaques Reifman, Krithika Rajaram, Sean T. Prigge, Shivendra G. Tewari, Anders Wallqvist

    المصدر: Antimicrob Agents Chemother

    مصطلحات موضوعية: Purine, Plasmodium falciparum, Apicoplasts, 03 medical and health sciences, chemistry.chemical_compound, Antimalarials, Prenylation, Fosfomycin, parasitic diseases, medicine, Parasite hosting, Humans, Pharmacology (medical), Nucleotide, Malaria, Falciparum, Mechanisms of Action: Physiological Effects, 030304 developmental biology, Pharmacology, chemistry.chemical_classification, 0303 health sciences, Apicoplast, biology, 030306 microbiology, Ribosomal RNA, biology.organism_classification, Fosmidomycin, Infectious Diseases, Biochemistry, chemistry, medicine.drug

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c029406473470a1bfcef389168f8251
    https://pubmed.ncbi.nlm.nih.gov/33495219

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  9. 9
    Transcriptional Inhibition of the F 1 F 0 -Type ATP Synthase Has Bactericidal Consequences on the Viability of Mycobacteria

    المؤلفون: Gregory M. Cook, Matthew B. McNeil, Justin F. Tirados, Heath W. K. Ryburn, Liam K. Harold

    المصدر: Antimicrob Agents Chemother

    مصطلحات موضوعية: Tuberculosis, Mycobacterium smegmatis, Drug target, Antitubercular Agents, Microbiology, Mycobacterium tuberculosis, 03 medical and health sciences, chemistry.chemical_compound, Adenosine Triphosphate, medicine, Humans, Pharmacology (medical), Mechanisms of Action: Physiological Effects, 030304 developmental biology, Pharmacology, 0303 health sciences, ATP synthase, biology, 030306 microbiology, Chemistry, medicine.disease, biology.organism_classification, Infectious Diseases, biology.protein, Bedaquiline

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faddb02b28b12e8a19b81cb9eefc2d80
    https://doi.org/10.1128/aac.00492-20

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  10. 10
    Unexpected Cell Wall Alteration-Mediated Bactericidal Activity of the Antifungal Caspofungin against Vancomycin-Resistant Enterococcus faecium

    المؤلفون: Fanny Joalland, Vincent Cattoir, Jean-Christophe Giard, Michel Auzou, Didier Goux, Pierrick Meignen, Felipe Cava, Sara B. Hernández, David Enot, Christophe Isnard, François Gravey, François Guérin

    المساهمون: Unité de Recherche Risques Microbiens (U2RM), Université de Caen Normandie (UNICAEN), Normandie Université (NU)-Normandie Université (NU), CHU Caen, Normandie Université (NU)-Tumorothèque de Caen Basse-Normandie (TCBN), Groupe de Recherche sur l'Adaptation Microbienne (GRAM 2.0), Université de Rouen Normandie (UNIROUEN), Normandie Université (NU)-Normandie Université (NU)-Université de Caen Normandie (UNICAEN), Normandie Université (NU), Umeå University, Centre de Microscopie Appliquée à la Biologie [Caen] (CMABio3), Interactions Cellules Organismes Environnement (ICORE), Normandie Université (NU)-Tumorothèque de Caen Basse-Normandie (TCBN)-Normandie Université (NU)-Tumorothèque de Caen Basse-Normandie (TCBN)-Université de Caen Normandie (UNICAEN), Normandie Université (NU)-CHU Caen, Institut Gustave Roussy (IGR), Métabolisme, cancer et immunité = Metabolism, Cancer & Immunity [CRC] (Equipe labellisée Ligue contre le cancer), Centre de Recherche des Cordeliers (CRC (UMR_S_1138 / U1138)), École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Université de Paris (UP)-École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Université de Paris (UP), CHU Pontchaillou [Rennes], ARN régulateurs bactériens et médecine (BRM), Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Normandie Université (NU)-Normandie Université (NU)-Université de Rouen Normandie (UNIROUEN), Normandie Université (NU)-Normandie Université (NU)-CHU Caen, Normandie Université (NU)-Tumorothèque de Caen Basse-Normandie (TCBN)-Tumorothèque de Caen Basse-Normandie (TCBN)-Université de Caen Normandie (UNICAEN), Normandie Université (NU)-Tumorothèque de Caen Basse-Normandie (TCBN)-Tumorothèque de Caen Basse-Normandie (TCBN), École Pratique des Hautes Études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Université Paris Cité (UPCité)-École Pratique des Hautes Études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Université Paris Cité (UPCité), Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Jonchère, Laurent, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Université Paris Cité (UPCité)-École pratique des hautes études (EPHE)

    المصدر: Antimicrob Agents Chemother
    Antimicrobial Agents and Chemotherapy
    Antimicrobial Agents and Chemotherapy, American Society for Microbiology, 2020, 64 (10), ⟨10.1128/AAC.01261-20⟩
    Antimicrobial Agents and Chemotherapy, 2020, 64 (10), ⟨10.1128/AAC.01261-20⟩

    مصطلحات موضوعية: E. faecium, Antifungal Agents, VRE, medicine.drug_class, [SDV]Life Sciences [q-bio], Antibiotics, Enterococcus faecium, Microbial Sensitivity Tests, Biology, Bacterial cell structure, Microbiology, Vancomycin-Resistant Enterococci, echinocandins, 03 medical and health sciences, chemistry.chemical_compound, Antibiotic resistance, Caspofungin, Cell Wall, Vancomycin, Intensive care, medicine, Humans, Pharmacology (medical), [SDV.MP] Life Sciences [q-bio]/Microbiology and Parasitology, Mechanisms of Action: Physiological Effects, Gram-Positive Bacterial Infections, 030304 developmental biology, Pharmacology, 0303 health sciences, 030306 microbiology, biochemical phenomena, metabolism, and nutrition, biology.organism_classification, bacterial infections and mycoses, 3. Good health, Anti-Bacterial Agents, [SDV] Life Sciences [q-bio], antibacterial, [SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology, Infectious Diseases, Cell wall organization, chemistry, Peptidoglycan

    وصف الملف: application/pdf

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29157f33073b96e58cd2d78ecc573284
    https://pubmed.ncbi.nlm.nih.gov/32778553

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