نتائج البحث - "Gordon D. Brown"

1

Complement-Mediated Differential Immune Response of Human Macrophages to Sporothrix Species Through Interaction With Their Cell Wall Peptidorhamnomannans

المؤلفون: Catherine Simenel, Vishukumar Aimanianda, Leila M. Lopes-Bezerra, J. Iñaki Guijarro, Sarah Sze Wah Wong, Neil A. R. Gow, Gabriela W. P. Neves, Janet A. Willment, Carol A. Munro, Gordon D. Brown, Catriona A Walls

المساهمون: State University of Rio de Janeiro, Mycologie moléculaire - Molecular Mycology, Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Plateforme Technologique de RMN Biologique et HDX-MS - Biological NMR and HDX-MS Technological Platform, University of Aberdeen, University of Exeter, Universidade de São Paulo = University of São Paulo (USP), This work was supported by Fundação de Apoio à Pesquisa do Distrito Federal (FAP-DF)/CNPq, PRONEX grant ID: FAP-DF, 0193.001.200/2016. VA is supported by the Centre Franco-Indien pour la Promotion de la Recherche Avancée (CEFIPRA) grant no. 5403-1 and ANR-DFG AfuINF grant. JG, VA, and CS were supported by the ANR-FUNHYDRO (ANR-16S-CE110020-01) grant. NG, GB, and JW are supported by the Welcome Trust (102705, 097377, 101873, 215599, and 200208) and the Medical Research Council Centre for Medical Mycology (MR/N006364/2)., ANR-16-CE11-0020,FUNHYDRO,Amyloïdes fonctionnels formés par les hydrophobines du pathogène fongique Aspergillus fumigatus(2016)

المصدر: Frontiers in Immunology
Frontiers in Immunology, 2021, 12, pp.749074. ⟨10.3389/fimmu.2021.749074⟩
Frontiers in Immunology, Vol 12 (2021)

مصطلحات موضوعية: peptidorhamnomannan (PRM), Antigens, Fungal, Immunology, Macrophage-1 Antigen, Microbiology, Immune system, Phagocytosis, Cell Wall, medicine, Sporothrix brasiliensis, Immunology and Allergy, Sporothrix schenckii, Humans, skin and connective tissue diseases, Complement Activation, [SDV.MP.MYC]Life Sciences [q-bio]/Microbiology and Parasitology/Mycology, Original Research, Glycoproteins, human macrophages, Innate immune system, [SDV.BBM.BS]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Structural Biology [q-bio.BM], biology, Sporotrichosis, L-Lactate Dehydrogenase, Macrophages, Sporothrix, Pathogen-Associated Molecular Pattern Molecules, Complement System Proteins, RC581-607, biology.organism_classification, medicine.disease, bacterial infections and mycoses, Complement system, Antibody opsonization, complement receptor-3 (CR3), Integrin alpha M, biology.protein, innate immune response, [SDV.IMM]Life Sciences [q-bio]/Immunology, Cytokines, Immunologic diseases. Allergy

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfedb19fede5f69dd34787e609bd8ae5
http://europepmc.org/articles/PMC8636148

2

MelLec Exacerbates the Pathogenesis of Aspergillus fumigatus-Induced Allergic Inflammation in Mice

المؤلفون: Janet A. Willment, Raif Yuecel, Ivy M. Dambuza, Kazuyoshi Kuwano, Carol Wallace, Kazuya Tone, Fabián Salazar, Remi Hatinguais, Gordon D. Brown, Petruta L Morvay, Mark H. T. Stappers

المصدر: Frontiers in Immunology, Vol 12 (2021)

مصطلحات موضوعية: Chemokine, Allergy, MelLec, biology, business.industry, Aspergillus fumigatus, Immunology, asthma, RC581-607, biology.organism_classification, medicine.disease, allergy, Proinflammatory cytokine, Allergic inflammation, Pathogenesis, C-type lectin, biology.protein, Immunology and Allergy, Medicine, Immunologic diseases. Allergy, Receptor, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dca7a47adce3d4841579289e86d0c069
https://www.frontiersin.org/articles/10.3389/fimmu.2021.675702/full

3

Immune cells fold and damage fungal hyphae

المؤلفون: Delma S. Childers, Arnab Pradhan, Kevin R. MacKenzie, Daniel E. Larcombe, M Fernanda Alonso, Johanna Louw, Catriona A Walls, Gordon D. Brown, Alistair J. P. Brown, Neil A. R. Gow, Gabriela Mol Avelar, Leanne E. Lewis, Mihai G. Netea, Lars Erwig, Judith M. Bain

المصدر: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences

مصطلحات موضوعية: Hyphal growth, Hypha, Podosome, Phagocytosis, Hyphae, chemical and pharmacologic phenomena, Biology, Microbiology, mechanical force, 03 medical and health sciences, Mice, 0302 clinical medicine, Immune system, Immunology and Inflammation, AMP-Activated Protein Kinase Kinases, Live cell imaging, Candida albicans, Animals, Humans, Lectins, C-Type, Cells, Cultured, 030304 developmental biology, 0303 health sciences, Multidisciplinary, Innate immune system, podosomes, Macrophages, fungi, cytoskeleton, Actomyosin, Biological Sciences, biology.organism_classification, fungal hyphae, 3. Good health, RAW 264.7 Cells, CD18 Antigens, Cell Adhesion Molecules, Protein Kinases, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3037a1b3194ee0d012b6b32c2da8be0a
https://pubmed.ncbi.nlm.nih.gov/33876755

4

Mycobiota dysbiosis: a new nexus in intestinal tumorigenesis

المؤلفون: Neil A. R. Gow, Nicolas Papon, Gordon D. Brown

المساهمون: Groupe d'Étude des Interactions Hôte-Pathogène (GEIHP), Université d'Angers (UA), SFR UA 4208 Interactions Cellulaires et Applications Thérapeutiques (ICAT)

المصدر: The EMBO Journal
EMBO Journal
EMBO Journal, EMBO Press, 2021, ⟨10.15252/embj.2021108175⟩

مصطلحات موضوعية: dectin‐3, Mycobiota, Colorectal cancer, Carcinogenesis, [SDV]Life Sciences [q-bio], Immunology, Energy metabolism, ILC3, colorectal cancer, Gut flora, medicine.disease_cause, General Biochemistry, Genetics and Molecular Biology, Article, Intestinal tumorigenesis, 03 medical and health sciences, 0302 clinical medicine, Candida albicans, medicine, Humans, Lymphocytes, Molecular Biology, ComputingMilieux_MISCELLANEOUS, 030304 developmental biology, Cancer, 0303 health sciences, General Immunology and Microbiology, biology, General Neuroscience, Innate lymphoid cell, IL‐22, Articles, biology.organism_classification, medicine.disease, Immunity, Innate, Gastrointestinal Microbiome, Metabolism, Dysbiosis, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93168c4c8f88540b49dbf89563fa2255
http://hdl.handle.net/20.500.12278/39664

View record at Wiley

5

Mitochondrial Reactive Oxygen Species Regulate Immune Responses of Macrophages to Aspergillus fumigatus

المؤلفون: Alistair J. P. Brown, Gordon D. Brown, Remi Hatinguais, Adilia Warris, Arnab Pradhan, Elena Shekhova

المصدر: Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology

مصطلحات موضوعية: lcsh:Immunologic diseases. Allergy, 0301 basic medicine, Mitochondrial ROS, Immunology, Respiratory chain, reverse electron transport, medicine.disease_cause, Microbiology, Aspergillus fumigatus, Electron Transport, Mice, 03 medical and health sciences, 0302 clinical medicine, medicine, Animals, Aspergillosis, Immunology and Allergy, Original Research, reactive oxygen species, chemistry.chemical_classification, Reactive oxygen species, Electron Transport Complex I, NADPH oxidase, biology, Chemistry, Aspegillus fumigatus, biology.organism_classification, cytokines, macrophages, Respiratory burst, mitochondria, 030104 developmental biology, biology.protein, Cytokine secretion, lcsh:RC581-607, 030217 neurology & neurosurgery, Oxidative stress

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a9d5c84fe50b362b478d63dec94c238
https://doi.org/10.3389/fimmu.2021.641495

6

Red blood cell mannoses as phagocytic ligands mediating both sickle cell anaemia and malaria resistance

المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications
Cao, H, Antonopoulos, A, Henderson, S, Wassall, H, Brewin, J, Masson, A, Shepherd, J, Konieczny, G, Patel, B, Williams, M-L, Davie, A, Forrester, M A, Hall, L, Minter, B, Tampakis, D, Moss, M, Lennon, C, Pickford, W, Erwig, L, Robertson, B, Dell, A, Brown, G D, Wilson, H M, Rees, D C, Haslam, S M, Alexandra Rowe, J, Barker, R N & Vickers, M A 2021, ' Red blood cell mannoses as phagocytic ligands mediating both sickle cell anaemia and malaria resistance ', Nature Communications, vol. 12, no. 1, 1792 . https://doi.org/10.1038/s41467-021-21814

مصطلحات موضوعية: 0301 basic medicine, Erythrocytes, Glycobiology, General Physics and Astronomy, Mannose, Ligands, chemistry.chemical_compound, 0302 clinical medicine, Spectrin, Malaria, Falciparum, Receptors, Immunologic, Phagocytes, Multidisciplinary, Membrane Glycoproteins, biology, Chemistry, Pattern recognition receptor, hemic and immune systems, Flow Cytometry, Hemolysis, 3. Good health, Multidisciplinary Sciences, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Science & Technology - Other Topics, Mannose receptor, Protein Binding, Pattern recognition receptors, Science, Plasmodium falciparum, Anemia, Sickle Cell, Article, General Biochemistry, Genetics and Molecular Biology, Microbiology, 03 medical and health sciences, Phagocytosis, Polysaccharides, medicine, Humans, Sickle cell trait, Science & Technology, Sickle cell disease, Erythrocyte Membrane, General Chemistry, medicine.disease, biology.organism_classification, Malaria, Red blood cell, 030104 developmental biology

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd89a3aee2973519b6303389fca5a20d
http://hdl.handle.net/10044/1/89825

7

Synthesis of the fungal metabolite YWA1 and related constructs as tools to study MelLec-mediated immune response to Aspergillus infections

المؤلفون: Chiara Zanato, Monica Piras, Christina Nikolakopoulou, Matteo Zanda, Nikki L. Sloan, Janet A. Willment, Ilaria Patruno, Gordon D. Brown

المصدر: Journal of organic chemistry 86 (2021): 6044–6055. doi:10.1021/acs.joc.0c02324
info:cnr-pdr/source/autori:1 Monica Piras,1 Ilaria Patruno,2-3 Christina Nikolakopoulou,2-3 Janet A Willment,4 Nikki Sloan,5 Chiara Zanato,2-3 Gordon Brown*(Corresponding Author), 1-4-6 Matteo Zanda* (Corresponding Author)/titolo:Synthesis of the fungal metabolite YWA1 and related constructs as tools to study MelLec-mediated immune response to Aspergillus infections/doi:10.1021%2Facs.joc.0c02324/rivista:Journal of organic chemistry/anno:2021/pagina_da:6044/pagina_a:6055/intervallo_pagine:6044–6055/volume:86