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المؤلفون: Alexis De Haven Brandon, Simon R. Stockwell, Florence I. Raynaud, May Elbanna, Paul Workman, Jamie Freeman, Suzanne A. Eccles, Angela Hayes, Sibylle Mittnacht, Chi Zhang, Paul A. Clarke, Robin Ketteler, Bissan Al-Lazikani
المساهمون: Stockwell, Simon [0000-0002-3345-8945], Apollo - University of Cambridge Repository
المصدر: Oncogene
مصطلحات موضوعية: Proto-Oncogene Mas, Article, Receptor tyrosine kinase, Focal adhesion, Mice, 03 medical and health sciences, 0302 clinical medicine, Biomarkers, Tumor, SKP2, Animals, Humans, 030304 developmental biology, 0303 health sciences, biology, Kinase, Cell Cycle, Cyclin-Dependent Kinase 2, Correction, Growth factor signalling, Cyclin-Dependent Kinase 4, Cyclin-Dependent Kinase 6, Proto-Oncogene Proteins c-met, Cell cycle, 3. Good health, Ubiquitin ligase, Cell biology, Checkpoint signalling, A549 Cells, Focal Adhesion Protein-Tyrosine Kinases, 030220 oncology & carcinogenesis, Cancer cell, biology.protein, Heterografts, biological phenomena, cell phenomena, and immunity, Cell Division, CDK inhibitor
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2faa136df2f17f25d688f01eb7a5fdc1
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المؤلفون: Louise Blair, Igor Stagljar, Julia Petschnigg, Igor Jurisica, Max Kotlyar, Robin Ketteler
المصدر: Journal of Molecular Biology
مصطلحات موضوعية: 0301 basic medicine, PEI, polyethylenimine, TF, transcription factor, Receptor tyrosine kinase, TACC, transforming acidic coiled-coil protein, Small hairpin RNA, ERK, extracellular signal-regulated kinase, Structural Biology, SRE, serum response element, Carcinoma, Non-Small-Cell Lung, ERBB3, Epidermal growth factor receptor, Nub, N-terminal half of ubiquitin, oncogenic signaling, Phosphorylation, RNA, Small Interfering, MOI, multiplicity of infection, GFP, green fluorescent protein, DMEM, Dulbecco's modified Eagle's medium, biology, 3. Good health, ErbB Receptors, Gene Expression Regulation, Neoplastic, two-hybrid screening, GRB2, Mitogen-Activated Protein Kinases, Microtubule-Associated Proteins, Signal Transduction, FGFR, fibroblast growth factor receptor, Cell Survival, EGFR-ex19del, EGFR-exon19 deletion, EGFR, PBS, phosphate-buffered saline, Article, 03 medical and health sciences, TKI, TK inhibitor, SH, Src homology, NSCLC, non-small cell lung cancer, Humans, Immunoprecipitation, Protein Interaction Domains and Motifs, KM, Kaplan–Meier, Protein kinase A, Molecular Biology, PI3K/AKT/mTOR pathway, non-small cell lung cancer, GO, gene ontology, EGF, epidermal growth factor, TK, tyrosine kinase, Computational Biology, EGFR-WT, EGFR-wildtype, Molecular biology, EGFR, epidermal growth factor receptor, Grb2, growth factor receptor-bound protein 2, 030104 developmental biology, HEK293 Cells, protein–protein interaction, MaMTH, mammalian membrane two-hybrid, Cancer research, biology.protein, Cyclin-dependent kinase 8, Cub, C-terminal half of ubiquitin, Gene Deletion, MAPK, mitogen-activated protein kinase, HeLa Cells