المؤلفون: Ulla Kampmann, Janne R. Hingst, Niels Jessen, Jørgen F. P. Wojtaszewski, Mads Svart, Niels Møller, Thomas Schmidt Voss, Mikkel H. Vendelbo

المصدر: Voss, T S, Vendelbo, M, Opstrup, U K, Hingst, J R, Wojtaszewski, J F P, Svart, M, Møller, N & Jessen, N 2017, ' Acute Hypoglycemia in Healthy Humans Impairs Insulin Stimulated Glucose Uptake and Glycogen Synthase in Skeletal Muscle; a Randomized Clinical Study ', Diabetes, vol. 66, no. 9, pp. 2483-2494 . https://doi.org/10.2337/db16-1559

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, medicine.medical_specialty, Adolescent, endocrine system diseases, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Glucose uptake, Glycogen Synthase/genetics, Gene Expression Regulation, Enzymologic/drug effects, Hypoglycemia, medicine.disease_cause, Gene Expression Regulation, Enzymologic, Young Adult, 03 medical and health sciences, Glucose Transporter Type 4/genetics, Muscle, Skeletal/enzymology, Internal medicine, Internal Medicine, medicine, Insulin, Glucose/metabolism, Humans, Amino Acid Sequence, Phosphorylation, Muscle, Skeletal, Hyperinsulinemic hypoglycemia, Glycogen synthase, Glucose Transporter Type 4, Cross-Over Studies, biology, business.industry, Glucose transporter, nutritional and metabolic diseases, Skeletal muscle, Hypoglycemia/etiology, medicine.disease, Insulin/adverse effects, Insulin receptor, Glucose, Glycogen Synthase, 030104 developmental biology, medicine.anatomical_structure, Endocrinology, biology.protein, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b27ddeca9d3fd63a619eb4e9fe63b84
https://doi.org/10.2337/db16-1559

المؤلفون: Galia Zamaratskaia, Marjeta Čandek-Potokar, Rebekka Thøgersen, Martin Krøyer Rasmussen

المصدر: Zamaratskaia, G, Thøgersen, R, Candek-Potokar, M & Rasmussen, M K 2018, ' Co-treatment with indole-3-carbinol and resveratrol modify porcine CYP1A and CYP3A activities and expression ', Xenobiotica, vol. 48, no. 3, pp. 232-240 . https://doi.org/10.1080/00498254.2017.1300708

مصطلحات موضوعية: 0301 basic medicine, Male, Receptors, Steroid, Indoles, CYP3A, Swine, Health, Toxicology and Mutagenesis, Cytochrome P-450 CYP3A Inhibitors/pharmacology, Resveratrol, Pharmacology, Toxicology, Biochemistry, ENTIRE MALE PIGS, HEPATOCYTES, chemistry.chemical_compound, food–drug, Food-Drug Interactions, 0302 clinical medicine, Stilbenes, Indole-3-carbinol, Receptors, Steroid/genetics, Cytochrome P-450 CYP3A, MESSENGER-RNA EXPRESSION, DIETARY INDOLE-3-CARBINOL, DRUG-INTERACTION, Regulation of gene expression, biology, Indoles/pharmacology, Pregnane X Receptor, General Medicine, Cytochrome P-450 CYP3A/genetics, 030220 oncology & carcinogenesis, RED WINE, Microsomes, Liver, Detoxification, Hepatocytes/drug effects, food-drug, Cytochrome P-450 CYP1A1/antagonists & inhibitors, ARYL-HYDROCARBON RECEPTOR, Gene Expression Regulation, Enzymologic/drug effects, METABOLISM, liver, Gene Expression Regulation, Enzymologic, 03 medical and health sciences, gene-regulation, Cytochrome P-450 CYP1A1, Animals, SKATOLE, secondary plant metabolites, Messenger RNA, CYP1A2, Cytochrome P450, CYTOCHROME-P450, Receptors, Aryl Hydrocarbon/genetics, 030104 developmental biology, chemistry, Receptors, Aryl Hydrocarbon, Stilbenes/pharmacology, biology.protein, Microsome, Hepatocytes, Microsomes, Liver/drug effects, Cytochrome P-450 CYP3A Inhibitors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54ca17c2bb409623a55f3711d3c49d0c

المؤلفون: Apostolos Zarros, Stamatios Theocharis, Panagiota Galanopoulou, Dimitrios Segos, Maria Konstandi, Charis Liapi, Marios Marselos, Matti A. Lang

المصدر: Journal of Applied Toxicology. 29:101-109

مصطلحات موضوعية: Cytochrome P-450 CYP2E1/metabolism, Male, Liver/*drug effects/enzymology, Cytochrome P-450 CYP2B1/metabolism, Pharmacology, Toxicology, chemistry.chemical_compound, Choline, Glutathione Transferase, biology, Alanine Transaminase, Cytochrome P-450 CYP2E1, Analgesics, Non-Narcotic, Glutathione, Choline Deficiency, Liver, Phenobarbital, Toxicity, Microsomes, Liver, Aspartate Aminotransferases/blood, Alkaline phosphatase, Glutathione Transferase/metabolism, Choline Deficiency/*metabolism, medicine.drug, Microsomes, Liver/enzymology/metabolism, medicine.medical_specialty, Cytochrome P-450 CYP1A1/metabolism, Gene Expression Regulation, Enzymologic/drug effects, Acetaminophen/*pharmacology, Gene Expression Regulation, Enzymologic, Cytochrome P-450 CYP1A2, Internal medicine, Cytochrome P-450 CYP1A1, medicine, Animals, Body Weight/drug effects, Aspartate Aminotransferases, Alanine Transaminase/blood, Rats, Wistar, Acetaminophen, Analgesics, Non-Narcotic/*pharmacology, Body Weight, Alkaline Phosphatase, Glutathione/metabolism, Rats, Endocrinology, Phenobarbital/*pharmacology, Alanine transaminase, chemistry, Alkaline Phosphatase/metabolism, Cytochrome P-450 CYP1A2/metabolism, Cytochrome P-450 CYP2B1, biology.protein, Drug metabolism

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b97dd08025883594307fb89c0a92995
https://doi.org/10.1002/jat.1386

المؤلفون: Susanna M.O. Hourani, Sapna Thakur, Catherine Ledent, Jian-Mei Li, Junjie Du

المصدر: The Journal of biological chemistry, 285 (51
The Journal of Biological Chemistry

مصطلحات موضوعية: Adenosine A2A receptor, Signal Transduction -- drug effects -- physiology, 030204 cardiovascular system & hematology, medicine.disease_cause, Biochemistry, p38 Mitogen-Activated Protein Kinases, Mice, 0302 clinical medicine, Adenosine deaminase, Enzyme Activation -- drug effects -- genetics, Endothelial dysfunction, Phosphorylation, Receptor, Cells, Cultured, chemistry.chemical_classification, Mice, Knockout, 0303 health sciences, Membrane Glycoproteins, Mitogen-Activated Protein Kinase 3, biology, Pyrimidines -- pharmacology, Angiotensin II, Cell Surface Receptor, Membrane Glycoproteins -- genetics -- metabolism, Mitogen-Activated Protein Kinase 3 -- genetics -- metabolism, Adenosine A2 Receptor Antagonists, p38 Mitogen-Activated Protein Kinases -- genetics -- metabolism, medicine.anatomical_structure, Phosphorylation -- drug effects -- genetics, NADPH Oxidase 2, cardiovascular system, MAP Kinases (MAPKs), hormones, hormone substitutes, and hormone antagonists, Signal Transduction, circulatory and respiratory physiology, Endothelium, Receptor, Adenosine A2A, Angiotensin II -- metabolism -- pharmacology, Adenosine A2 Receptor Antagonists -- pharmacology, Gene Expression Regulation, Enzymologic, Reactive Oxygen Species -- metabolism, Gene Knockout, 03 medical and health sciences, Nox2, medicine, Animals, Gene Expression Regulation, Enzymologic -- drug effects -- genetics, Molecular Biology, Proto-Oncogene Proteins c-akt -- genetics -- metabolism, 030304 developmental biology, Reactive oxygen species, Endothelial Cells, NADPH Oxidases, Cell Biology, Triazoles, medicine.disease, Molecular biology, Receptor, Adenosine A2A -- genetics -- metabolism, Sciences biomédicales, Enzyme Activation, Pyrimidines, chemistry, Reactive Oxygen Species (ROS), biology.protein, Triazoles -- pharmacology, Reactive Oxygen Species, Proto-Oncogene Proteins c-akt, NADPH Oxidase -- biosynthesis -- genetics -- metabolism, Oxidative stress, Endothelial Cells -- metabolism

وصف الملف: 1 full-text file(s): application/pdf; text

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a7f2468fb8e9c9f71e6f0fc5a55bcee
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/124818

المؤلفون: Andrzej Sienkiewicz, László Forró, Botond Banfi, Olivier Plastre, Lena Serrander, Werner Schlegel, Karl-Heinz Krause, Karen Bedard, Bernard Lardy, Laetitia Cartier

المساهمون: Facultad de Medicina, GREPI, Techniques de l'Ingénierie Médicale et de la Complexité - Informatique, Mathématiques et Applications, Grenoble - UMR 5525 (TIMC-IMAG), VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Centre National de la Recherche Scientifique (CNRS)-Université Joseph Fourier - Grenoble 1 (UJF)-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Centre National de la Recherche Scientifique (CNRS)-Université Joseph Fourier - Grenoble 1 (UJF), Ecole Polytechnique Fédérale de Lausanne (EPFL)

المصدر: Biochemical Journal
Biochemical Journal, Portland Press, 2007, 406 (1), pp.105-14. ⟨10.1042/BJ20061903⟩
Biochemical Journal, Vol. 406, No 1 (2007) pp. 105-114

مصطلحات موضوعية: Time Factors, Mitochondrion, ddc:616.07, Enzyme Induction/drug effects, MESH: Superoxides, Biochemistry, MESH: Tetracycline, Cell Membrane/drug effects/enzymology, chemistry.chemical_compound, Mice, 0302 clinical medicine, Cytosol, MESH: Cytosol, Superoxides, Ethidium, MESH: Animals, Enzyme Inhibitors, MESH: NADPH Oxidase, chemistry.chemical_classification, Enzyme Inhibitors/pharmacology, 0303 health sciences, NADPH oxidase, biology, Superoxide, MESH: Gene Expression Regulation, Enzymologic, NOX4, MESH: NAD, MESH: Reactive Oxygen Species, Mitochondria/drug effects, Mitochondria, MESH: Nitroblue Tetrazolium, MESH: Enzyme Inhibitors, NADPH Oxidase 4, Enzyme Induction, cardiovascular system, MESH: Hydrogen Peroxide, NAD/metabolism, Superoxides/metabolism, MESH: NADP, Intracellular, Hydrogen Peroxide/pharmacology, Research Article, MESH: Enzyme Induction, RNA, Messenger/genetics/metabolism, MESH: Mitochondria, Gene Expression Regulation, Enzymologic/drug effects, Gene Expression Regulation, Enzymologic, Tetracycline/pharmacology, Cell Line, 03 medical and health sciences, Ethidium/analogs & derivatives/pharmacology, Animals, Humans, Cytosol/drug effects/enzymology, RNA, Messenger, [SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biochemistry [q-bio.BM], Molecular Biology, MESH: Mice, 030304 developmental biology, MESH: RNA, Messenger, Reactive oxygen species, MESH: Humans, urogenital system, NADPH Oxidase/ genetics, Nitroblue Tetrazolium, MESH: Time Factors, Cell Membrane, Electron Spin Resonance Spectroscopy, NADPH Oxidases, Cell Biology, Hydrogen Peroxide, Tetracycline, NADP/metabolism, NAD, Molecular biology, MESH: Ethidium, MESH: Cell Line, chemistry, biology.protein, Reactive Oxygen Species/ metabolism, MESH: Electron Spin Resonance Spectroscopy, NAD+ kinase, Reactive Oxygen Species, Nitroblue Tetrazolium/pharmacology, 030217 neurology & neurosurgery, NADP, MESH: Cell Membrane

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4bb68c120cdcace87036c6870419862
https://pubmed.ncbi.nlm.nih.gov/17501721

المؤلفون: Karl-Josef Dietz, Andrea Kandlbinder, Frank Horling, Iris Finkemeier, Janine König, Margarete Baier, Petra Lamkemeyer

مصطلحات موضوعية: Peroxiredoxins Peroxidases/*genetics/metabolism Plant Shoots/metabolism Oxidative Stress/*physiology Oxidation-Reduction Gene Expression Regulation Enzymologic/drug effects/radiation effects Hydrogen Peroxide/pharmacology Multigene Family/genetics Light Plant/drug effects/radiation effects Gene Expression Regulation Ascorbic Acid/*pharmacology Arabidopsis Proteins/*genetics/metabolism Arabidopsis/drug effects/*genetics/radiation effects, Light, Physiology, Arabidopsis, Context (language use), Plant Science, Ascorbic Acid, Dithiothreitol, Gene Expression Regulation, Enzymologic, chemistry.chemical_compound, Gene Expression Regulation, Plant, Gene expression, Genetics, Arabidopsis thaliana, biology, Arabidopsis Proteins, Hydrogen Peroxide, Peroxiredoxins, biology.organism_classification, Ascorbic acid, Oxidative Stress, chemistry, Biochemistry, Peroxidases, Multigene Family, biology.protein, Thioredoxin, Peroxiredoxin, Oxidation-Reduction, Plant Shoots, Peroxidase, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac9d0a80d407926a776fca66436e8a02
https://doi.org/10.1104/pp.010017

المؤلفون: Kristin K. Wobbe, David Staknis, Donald M. Coen, Paul Digard

المصدر: Wobbe, K K, Digard, P, Staknis, D & Coen, D M 1993, ' Unusual regulation of expression of the herpes simplex virus DNA polymerase gene ', Journal of Virology, vol. 67, no. 9, pp. 5419-25 . < http://jvi.asm.org/content/67/9/5419.long >
Europe PubMed Central

مصطلحات موضوعية: Phosphonoacetic Acid, Transcription, Genetic, DNA polymerase, viruses, RNA, Messenger/metabolism, DNA-Directed DNA Polymerase, Hydroxyurea/pharmacology, DNA polymerase delta, DNA-Directed DNA Polymerase/genetics, Transcription, Genetic/drug effects, Gene expression, Hydroxyurea, Simplexvirus, RNA, Viral/biosynthesis, RNA, Viral/antagonists & inhibitors, Polymerase, Gene Expression Regulation, Viral/drug effects, biology, Genes, pol, RNA, Viral, Research Article, Protein Biosynthesis/drug effects, DNA Replication, Gene Expression Regulation, Viral, Simplexvirus/enzymology, DNA polymerase II, Immunology, Gene Expression Regulation, Enzymologic/drug effects, Phosphonoacetic Acid/pharmacology, Ganciclovir/pharmacology, Microbiology, Thymidine Kinase, Gene Expression Regulation, Enzymologic, Aphidicolin, Virology, Simplexvirus/genetics, Animals, RNA, Messenger, Gene, Ganciclovir, Vero Cells, DNA synthesis, Aphidicolin/pharmacology, DNA-Directed DNA Polymerase/biosynthesis, Thymidine Kinase/biosynthesis, DNA replication, RNA, Messenger/biosynthesis, DNA Replication/drug effects, Molecular biology, Kinetics, Insect Science, Protein Biosynthesis, biology.protein, Simplexvirus/drug effects

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed5734e8364fb304b8962db28a860e64
https://pubmed.ncbi.nlm.nih.gov/8394456