المؤلفون: Jost, Marco, Chen, Yuwen, Gilbert, Luke A, Horlbeck, Max A, Krenning, Lenno, Menchon, Grégory, Rai, Ankit, Cho, Min Y, Stern, Jacob J, Prota, Andrea E, Kampmann, Martin, Akhmanova, Anna, Steinmetz, Michel O, Tanenbaum, Marvin E, Weissman, Jonathan S, Sub Cell Biology, Celbiologie

المساهمون: Hubrecht Institute for Developmental Biology and Stem Cell Research, Sub Cell Biology, Celbiologie

المصدر: Molecular Cell
Molecular Cell, 79(1), 191. Cell Press
Molecular Cell, 79(1), 191-198.e3. Cell Press

مصطلحات موضوعية: Protein Conformation, Mutant, Cell, medicine.disease_cause, Crystallography, X-Ray, Microtubules, 0302 clinical medicine, Tubulin, Neoplasms, Sulfones, Cells, Cultured, Glycine/analogs & derivatives, Mutation, 0303 health sciences, Cultured, Crystallography, biology, Chemistry, rigosertib, Rigosertib, drug mechanism of action, 3. Good health, Cell biology, medicine.anatomical_structure, chemical genetics, Pharmaceutical Preparations, 030220 oncology & carcinogenesis, Pharmaceutical Preparations/chemistry, Drug Contamination, Antineoplastic Agents/pharmacology, Cells, Glycine, Antineoplastic Agents, Article, 03 medical and health sciences, CRISPRa, Tubulin/chemistry, Microtubule, medicine, Humans, Binding site, Molecular Biology, 030304 developmental biology, Cell Proliferation, drug target identification, CRISPRi, Cell Biology, In vitro, Neoplasms/drug therapy, Sulfones/pharmacology, Cancer cell, X-Ray, biology.protein, Microtubules/drug effects, 030217 neurology & neurosurgery

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78e69dbc0caaaee2c44b7494dfd72fa4
https://pubmed.ncbi.nlm.nih.gov/32619469

المؤلفون: Hugues Henry, Elidie Béard, Layane Hanna-El-Daher, Liliane Tenenbaum, Olivier Braissant

المصدر: Neurobiology of Disease, Vol 79, Iss, Pp 14-27 (2015)
Neurobiology of Disease, vol. 79, pp. 14-27

مصطلحات موضوعية: Apoptosis, Rats, Sprague-Dawley, chemistry.chemical_compound, Neurons/enzymology, Neuroglia/enzymology, Gap-43 protein, Guanidinoacetate N-Methyltransferase/deficiency, Cells, Cultured, Glycine/analogs & derivatives, Neurons, Dependovirus/genetics, biology, Receptors, GABA-A/metabolism, Brain, Apoptosis/physiology, Dependovirus, Brain/enzymology, Guanidinoacetate N-methyltransferase, Neurology, RNA Interference, Brain/embryology, Neuroglia, GAMT deficiency, Glycine/metabolism, medicine.medical_specialty, Programmed cell death, Genetic Vectors, Glycine, Guanidinoacetate methyltransferase deficiency, Development, Creatine, lcsh:RC321-571, Internal medicine, Axons/enzymology, medicine, Animals, DAPI, Creatine deficiency syndromes, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, Guanidinoacetate, Receptors, GABA-A, medicine.disease, Guanidinoacetate N-Methyltransferase/genetics, Molecular biology, Axons, Coculture Techniques, Endocrinology, chemistry, Creatine/metabolism, biology.protein, Guanidinoacetate N-Methyltransferase, NeuN

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cf7687b863583faf1bb48442403ebc2
http://www.sciencedirect.com/science/article/pii/S0969996115001266