نتائج البحث - "Marie-France Hamou"

1

Hyperpolarized 13C-glucose magnetic resonance highlights reduced aerobic glycolysis in vivo in infiltrative glioblastoma

المؤلفون: Arnaud Comment, Olga Gusyatiner, Bernard Lanz, Jocelyne Bloch, Irene Vassallo, Marie-France Hamou, Mor Mishkovsky, Rolf Gruetter, Monika E. Hegi, Cristina Cudalbu

المساهمون: Comment, Arnaud [0000-0002-8484-3448], Apollo - University of Cambridge Repository

المصدر: Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Scientific reports, vol. 11, no. 1, pp. 5771

مصطلحات موضوعية: Aerobiosis, Animals, Aspartic Acid/analogs & derivatives, Aspartic Acid/metabolism, Brain Neoplasms/diagnostic imaging, Brain Neoplasms/metabolism, Carbon Isotopes/chemistry, Cell Line, Tumor, Glioblastoma/diagnostic imaging, Glioblastoma/metabolism, Glucose/metabolism, Glycolysis, Humans, Lactic Acid/metabolism, Magnetic Resonance Imaging, Metabolomics, Mice, SCID, Pyruvic Acid/metabolism, Science, Brain tumor, Lesion, 03 medical and health sciences, 0302 clinical medicine, In vivo, Pyruvic Acid, medicine, Lactic Acid, 030304 developmental biology, 0303 health sciences, Aspartic Acid, Carbon Isotopes, Multidisciplinary, medicine.diagnostic_test, Chemistry, Brain Neoplasms, urogenital system, Hyperpolarized 13c, Magnetic resonance imaging, medicine.disease, Warburg effect, nervous system diseases, Glucose, Anaerobic glycolysis, Cancer research, Medicine, medicine.symptom, Glioblastoma, 030217 neurology & neurosurgery

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfa14681a1f7028751b759d63f316269
https://doaj.org/article/63f02f86298445728f1acfcb8546e62d

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2

Metabolic and transcriptomic profiles of glioblastoma invasion revealed by comparisons between patients and corresponding orthotopic xenografts in mice

المؤلفون: Jean-Philippe Brouland, Cristina Cudalbu, Lijing Xin, Andreas F. Hottinger, Roy Thomas Daniel, Monika E. Hegi, Pierre Bady, Marta Lai, Olga Gusyatiner, Mario Lepore, Marie-France Hamou

المصدر: Acta neuropathologica communications, vol. 9, no. 1, pp. 133
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-16 (2021)
Acta Neuropathologica Communications
BioRxiv

مصطلحات موضوعية: Adult, Male, spectroscopy, Proton Magnetic Resonance Spectroscopy, medicine.medical_treatment, Brain tumor, Biology, Blood–brain barrier, in-vivo, Extracellular matrix, Transcriptome, Mice, patient-derived orthotopic xenografts (pdox), In vivo, 1H MRS at ultra-high fields (UHF), h-1 mrs, medicine, Animals, Humans, Neoplasm Invasiveness, microenvironmental landscape, RC346-429, human brain, genome, Aged, tumor host interaction, Brain Neoplasms, Research, subtypes, Growth factor, glioblastoma, Middle Aged, Brain Neoplasms/diagnostic imaging, Brain Neoplasms/genetics, Brain Neoplasms/metabolism, Brain Neoplasms/pathology, Female, Glioblastoma/diagnostic imaging, Glioblastoma/genetics, Glioblastoma/metabolism, Glioblastoma/pathology, Magnetic Resonance Imaging, Metabolome, Neoplasm Transplantation, Glioblastoma, Invasion, Patient-derived orthotopic xenografts (PDOX), Tumor host interaction, invasion, bioconductor, medicine.disease, tesla, h-1 mrs at ultra-high fields (uhf), medicine.anatomical_structure, Tumor progression, Cancer research, Neurology. Diseases of the nervous system, transcriptome, Extracellular Matrix Degradation

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7278226f5c798527e12857fb894c162
https://serval.unil.ch/notice/serval:BIB_CB8B36AE633E

3

Hyperpolarized

المؤلفون: Mor, Mishkovsky, Olga, Gusyatiner, Bernard, Lanz, Cristina, Cudalbu, Irene, Vassallo, Marie-France, Hamou, Jocelyne, Bloch, Arnaud, Comment, Rolf, Gruetter, Monika E, Hegi

المصدر: Scientific Reports

مصطلحات موضوعية: Aspartic Acid, Carbon Isotopes, urogenital system, Brain Neoplasms, Biophysics, Diseases, Mice, SCID, Magnetic Resonance Imaging, Biochemistry, Aerobiosis, Article, nervous system diseases, Chemistry, Glucose, Physical chemistry, Cell Line, Tumor, Biophysical chemistry, Pyruvic Acid, Animals, Humans, Metabolomics, Lactic Acid, Glioblastoma, Glycolysis, Cancer

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::b40eba2d2a1b35e3de8d18ac682a3a09
https://pubmed.ncbi.nlm.nih.gov/33707647

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4

Phase II Study of Radiotherapy and Temsirolimus versus Radiochemotherapy with Temozolomide in Patients with Newly Diagnosed Glioblastoma without MGMT Promoter Hypermethylation (EORTC 26082)

المساهمون: Neurology, University of Zurich, Wick, Wolfgang

المصدر: Clinical Cancer Research, 22(19), 4797-4806. American Association for Cancer Research Inc.
Clinical Cancer Research, 22(19), 4797-4806
Clinical Cancer Research
Clinical cancer research, vol. 22, no. 19, pp. 4797-4806

مصطلحات موضوعية: 0301 basic medicine, Oncology, Male, Cancer Research, Phases of clinical research, Kaplan-Meier Estimate, 0302 clinical medicine, 1306 Cancer Research, Promoter Regions, Genetic, DNA Modification Methylases, education.field_of_study, Brain Neoplasms, Chemoradiotherapy, Middle Aged, Temsirolimus, 3. Good health, Dacarbazine, 030220 oncology & carcinogenesis, 2730 Oncology, Female, medicine.drug, Adult, medicine.medical_specialty, Population, 610 Medicine & health, 03 medical and health sciences, Young Adult, Internal medicine, medicine, Temozolomide, Humans, education, Aged, Proportional Hazards Models, Brain Neoplasms/drug therapy, Brain Neoplasms/mortality, Brain Neoplasms/radiotherapy, Chemoradiotherapy/methods, DNA Methylation, DNA Modification Methylases/genetics, DNA Repair Enzymes/genetics, Dacarbazine/administration & dosage, Dacarbazine/analogs & derivatives, Glioblastoma/drug therapy, Glioblastoma/mortality, Glioblastoma/radiotherapy, Promoter Regions, Genetic/genetics, Sirolimus/administration & dosage, Sirolimus/analogs & derivatives, Tumor Suppressor Proteins/genetics, Sirolimus, Performance status, business.industry, Tumor Suppressor Proteins, Surgery, 10040 Clinic for Neurology, 030104 developmental biology, DNA Repair Enzymes, 10032 Clinic for Oncology and Hematology, MGMT-Unmethylated Glioblastoma, business, Glioblastoma

وصف الملف: 1078-0432.CCR-15-3153.full.pdf - application/pdf; application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9d7fef0d1608d3697456d8fd4775b80
https://doi.org/10.1158/1078-0432.ccr-15-3153

5

In vivo characterization of brain metabolism by

المؤلفون: Marta, Lai, Irene, Vassallo, Bernard, Lanz, Carole, Poitry-Yamate, Marie-France, Hamou, Cristina, Cudalbu, Rolf, Gruetter, Monika E, Hegi

المصدر: International journal of cancer. 143(1)

مصطلحات موضوعية: Male, Aspartic Acid, Brain Neoplasms, Proton Magnetic Resonance Spectroscopy, Brain, Glutamic Acid, Glioma, Repressor Proteins, Mice, Glucose, Fluorodeoxyglucose F18, Cell Line, Tumor, Positron-Emission Tomography, Animals, Humans, Oxidation-Reduction, Neoplasm Transplantation, gamma-Aminobutyric Acid, Adaptor Proteins, Signal Transducing

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::12ada77faeb6db1dbf9715b8b4c7f873
https://pubmed.ncbi.nlm.nih.gov/29417580

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6

WIF1 re-expression in glioblastoma inhibits migration through attenuation of non-canonical WNT signaling by downregulating the lncRNA MALAT1

المؤلفون: Monika E. Hegi, Premnath Rajakannu, Marta Lai, Irene Vassallo, Marie-France Hamou, Pascal O. Zinn

المصدر: Oncogene
Oncogene, vol. 35, no. 1, pp. 12-21

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Adaptor Proteins, Signal Transducing/genetics, WIF1, Mice, Cell Movement, Glioblastoma/metabolism, Wnt Signaling Pathway, CIBM-AIT, Gene knockdown, Brain Neoplasms, Wnt signaling pathway, LRP6, LRP5, Cell migration, Adaptor Proteins, Signal Transducing/biosynthesis, Animals, Brain Neoplasms/genetics, Brain Neoplasms/metabolism, Cell Line, Tumor, Cell Movement/physiology, Cell Proliferation/physiology, Down-Regulation, Gene Expression Regulation, Neoplastic, Glioblastoma/genetics, Heterografts, Humans, Mice, Nude, Proto-Oncogene Proteins/genetics, Proto-Oncogene Proteins/metabolism, RNA, Long Noncoding/genetics, RNA, Long Noncoding/metabolism, Repressor Proteins/biosynthesis, Repressor Proteins/genetics, Signal Transduction, Wnt Proteins/genetics, Wnt Proteins/metabolism, WNT5A, Brain Neoplasms/pathology, RNA, Long Noncoding, Signal transduction, Biology, Wnt-5a Protein, 03 medical and health sciences, Proto-Oncogene Proteins, Genetics, Molecular Biology, Adaptor Proteins, Signal Transducing, Cell Proliferation, Repressor Proteins, Wnt Proteins, Glioblastoma/pathology, 030104 developmental biology, Immunology, Cancer research, Glioblastoma

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19548516f268809303ffcdcd42f25930

7

Presence of an oligodendroglioma-like component in newly diagnosed glioblastoma identifies a pathogenetically heterogeneous subgroup and lacks prognostic value: central pathology review of the EORTC_26981/NCIC_CE.3 trial

المؤلفون: Mathilde C.M. Kouwenhoven, Karima Mokhtari, René-Olivier Mirimanoff, Marie-France Hamou, Christian Hartmann, Danielle Martinet, Pieter Wesseling, Roger Stupp, A. von Deimling, M. J. van den Bent, Michael Weller, N Besuchet Schmutz, Wanyu L. Lambiv, Robert-Charles Janzer, Thierry Gorlia, Annie-Claire Diserens, Monika E. Hegi, Pierre Bady, Warren P. Mason

المساهمون: Pathology, CCA - Disease profiling, University of Zurich, Hegi, M E, Neurology, Radiation Oncology Groups, National Cancer Institute of Canada Clinical Trials Group, European Organisation for, Research, Treatment of Cancer Brain, Tumour

المصدر: Acta Neuropathologica, 123(6), 841-852. Springer Verlag
Acta Neuropathologica, 123, 841-52
Acta Neuropathologica, 123(6), 841-852. Springer-Verlag
Hegi, M E, Janzer, R C, Lambiv, W L, Gorlia, T, Kouwenhoven, M C, Hartmann, C, von Deimling, A, Martinet, D, Besuchet Schmutz, N, Diserens, A C, Hamou, M F, Bady, P, Weller, M, van den Bent, M J, Mason, W P, Mirimanoff, R O, Stupp, R, Mokhtari, K & Wesseling, P 2012, ' Presence of an oligodendroglioma-like component in newly diagnosed glioblastoma identifies a pathogenetically heterogeneous subgroup and lacks prognostic value: central pathology review of the EORTC_26981/NCIC_CE.3 trial ', Acta Neuropathologica, vol. 123, no. 6, pp. 841-852 . https://doi.org/10.1007/s00401-011-0938-4
Acta Neuropathologica, 123, 6, pp. 841-52
Acta neuropathologica
Acta Neuropathologica, vol. 123, no. 6, pp. 841-852

مصطلحات موضوعية: Male, Oncology, Pathology, medicine.medical_treatment, 2804 Cellular and Molecular Neuroscience, Central Pathology Review, 0302 clinical medicine, Brain Neoplasms, Chemoradiotherapy, Middle Aged, Prognosis, Translational research Tissue engineering and pathology [ONCOL 3], 3. Good health, Dacarbazine, ErbB Receptors, Treatment Outcome, 2728 Neurology (clinical), 030220 oncology & carcinogenesis, Female, medicine.drug, Adult, medicine.medical_specialty, IDH1, Adolescent, Oligodendroglioma, 610 Medicine & health, Pathology and Forensic Medicine, Young Adult, 03 medical and health sciences, Cellular and Molecular Neuroscience, Internal medicine, Temozolomide, medicine, Humans, Clinical significance, Aged, Brain Neoplasms/genetics, Brain Neoplasms/pathology, Clinical Trials, Phase III as Topic, DNA Methylation, Dacarbazine/analogs & derivatives, Dacarbazine/therapeutic use, Glioblastoma/genetics, Glioblastoma/pathology, Mutation, Oligodendroglioma/genetics, Oligodendroglioma/pathology, Receptor, Epidermal Growth Factor/genetics, Receptor, Epidermal Growth Factor/metabolism, Survival Analysis, Chemotherapy, business.industry, medicine.disease, 10040 Clinic for Neurology, nervous system diseases, 2734 Pathology and Forensic Medicine, Clinical trial, Component (group theory), Neurology (clinical), Glioblastoma, business, 030217 neurology & neurosurgery

وصف الملف: Sammelmappe1.pdf - application/pdf; application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1a5a1d3c56b8ef520162e875697e9dd
https://hdl.handle.net/2066/109138

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8

The Wnt inhibitory factor 1 (WIF1) is targeted in glioblastoma and has a tumor suppressing function potentially by induction of senescence

المؤلفون: Anastasia Murat, Davide Sciuscio, Burt G. Feuerstein, Annie-Claire Diserens, Mauro Delorenzi, Marie-France Hamou, Eugenia Migliavacca, Anjan Misra, Irene Vassallo, Monika E. Hegi, Eytan Domany, Raphaël Burger, Wanyu L. Lambiv, Tal Shay, Roger Stupp

المصدر: Neuro-Oncology. 13:736-747

مصطلحات موضوعية: Aging, Cancer Research, senescence, Signaling Pathway, Epigenetic Inactivation, Expression, WIF1, Epigenesis, Genetic, Immunoenzyme Techniques, Colorectal-Cancer Cells, Mice, Promoter Methylation, Genes, Tumor Suppressor, tumor suppressor gene, RNA, Small Interfering, Promoter Regions, Genetic, biology, Brain Neoplasms, Reverse Transcriptase Polymerase Chain Reaction, Wnt signaling pathway, LRP5, epigenetic silencing, Candidate Tumor Suppressor Gene, Gene Expression Regulation, Neoplastic, Oncology, Basic and Translational Investigations, Chromosomal region, Female, Beta-catenin, Tumor suppressor gene, Blotting, Western, Wnt pathway, Down-Regulation, Mice, Nude, Cell Line, Tumor, Cell Adhesion, Animals, Humans, Gene silencing, RNA, Messenger, neoplasms, Adaptor Proteins, Signal Transducing, Cell Proliferation, Newly-Diagnosed Glioblastoma, DNA Methylation, Beta-Catenin, Repressor Proteins, Factor-I, biology.protein, Cancer research, Adjuvant Temozolomide, Neurology (clinical), Glioblastoma, Wif1

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bcf65c552849bbb2fe83f755e434768
https://doi.org/10.1093/neuonc/nor036

9

Elevated levels of MIC-1/GDF15 in the cerebrospinal fluid of patients are associated with glioblastoma and worse outcome

المؤلفون: Samuel N. Breit, Monika E. Hegi, Isabelle Desbaillets, Anastasia Murat, Marie-France Hamou, Sophie Shnaper, Eugenia Migliavacca, Roger Stupp, Nicolas de Tribolet, Sandrine Ostermann, Myriam Schluep, David Brown

المصدر: International Journal of Cancer. 125:2624-2630

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16e305e9558fe74dbd03412ea4b29770
https://doi.org/10.1002/ijc.24639

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10

المساهمون: Neurology, CCA - Cancer biology and immunology, CCA - Imaging and biomarkers, CCA - Cancer Treatment and quality of life

المصدر: Murat, A, Migliavacca, E, Gorlia, T, Lambiv, W L, Shay, T, Hamou, M-F, de Tribolet, N, Regli, L, Wick, W, Kouwenhoven, M C M, Hainfellner, J A, Heppner, F L, Dietrich, P-Y, Zimmer, Y, Cairncross, J G, Janzer, R-C, Domany, E, Delorenzi, M, Stupp, R & Hegi, M E 2008, ' Stem cell-related "self-renewal" signature and high epidermal growth factor receptor expression associated with resistance to concomitant chemoradiotherapy in glioblastoma ', Journal of Clinical Oncology, vol. 26, no. 18, pp. 3015-24 . https://doi.org/10.1200/JCO.2007.15.7164
Journal of Clinical Oncology, 26(18), 3015-24. American Society of Clinical Oncology
Journal of Clinical Oncology, Vol. 26, No 18 (2008) pp. 3015-24

مصطلحات موضوعية: Adult, Cancer Research, Radiation Tolerance, Brain Neoplasms/enzymology/genetics/pathology/therapy, Growth factor receptor, Antineoplastic Agents, Alkylating/therapeutic use, Temozolomide, medicine, Humans, Combined Modality Therapy, ddc:576.5, Epidermal growth factor receptor, Antineoplastic Agents, Alkylating, Aged, ddc:616, biology, Brain Neoplasms, business.industry, Gene Expression Profiling, Dacarbazine/analogs & derivatives/therapeutic use, Genes, Homeobox, Cancer, Glioblastoma/enzymology/genetics/pathology/therapy, Middle Aged, medicine.disease, Dacarbazine, ErbB Receptors, Gene expression profiling, Adult Stem Cells, Oncology, Drug Resistance, Neoplasm, Receptor, Epidermal Growth Factor/biosynthesis/genetics, Multigene Family, Immunology, Adult Stem Cells/pathology, Cancer research, biology.protein, Stem cell, Glioblastoma, business, Chemoradiotherapy

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2496457cf2984a100140dce06dcf422d
https://doi.org/10.1200/jco.2007.15.7164

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