المؤلفون: Padilla N; Research Unit in Clinical and Translational Bioinformatics, Vall d'Hebron Institute of Research (VHIR). Universitat Autònoma de Barcelona, Barcelona, Spain., Moles-Fernández A; Oncogenetics Group, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain., Riera C; Research Unit in Clinical and Translational Bioinformatics, Vall d'Hebron Institute of Research (VHIR). Universitat Autònoma de Barcelona, Barcelona, Spain., Montalban G; Oncogenetics Group, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain., Özkan S; Research Unit in Clinical and Translational Bioinformatics, Vall d'Hebron Institute of Research (VHIR). Universitat Autònoma de Barcelona, Barcelona, Spain., Ootes L; Research Unit in Clinical and Translational Bioinformatics, Vall d'Hebron Institute of Research (VHIR). Universitat Autònoma de Barcelona, Barcelona, Spain., Bonache S; Oncogenetics Group, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain., Díez O; Oncogenetics Group, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain.; Area of Clinical and Molecular Genetics, University Hospital of Vall d'Hebron, Barcelona, Spain., Gutiérrez-Enríquez S; Oncogenetics Group, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain., de la Cruz X; Research Unit in Clinical and Translational Bioinformatics, Vall d'Hebron Institute of Research (VHIR). Universitat Autònoma de Barcelona, Barcelona, Spain.; Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain.

المصدر: Human mutation [Hum Mutat] 2019 Sep; Vol. 40 (9), pp. 1593-1611. Date of Electronic Publication: 2019 Jul 03.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 9215429 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-1004 (Electronic) Linking ISSN: 10597794 NLM ISO Abbreviation: Hum Mutat Subsets: MEDLINE

مواضيع طبية MeSH: BRCA1 Protein/*genetics , BRCA2 Protein/*genetics , Breast Neoplasms/*diagnosis , Computational Biology/*methods , Ovarian Neoplasms/*diagnosis, Breast Neoplasms/genetics ; Computer Simulation ; Early Detection of Cancer ; Female ; Genetic Predisposition to Disease ; Germ-Line Mutation ; Humans ; Models, Genetic ; Mutation, Missense ; Ovarian Neoplasms/genetics

المؤلفون: Cline MS; Genomics Institute, UC Santa Cruz, Santa Cruz, California., Babbi G; FaBiT Department, Biocomputing Group, University of Bologna, Bologna, Italy., Bonache S; Oncogenetics Group, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain., Cao Y; Department of Electrical and Computer Engineering, Texas A&M University, College Station, Texas., Casadio R; FaBiT Department, Biocomputing Group, University of Bologna, Bologna, Italy., de la Cruz X; Clinical and Translational Bioinformatics Research Unit, Vall d'Hebron Institute of Research (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain.; Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain., Díez O; Oncogenetics Group, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain.; Clinical and Translational Bioinformatics Research Unit, Vall d'Hebron Institute of Research (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain., Gutiérrez-Enríquez S; Oncogenetics Group, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain., Katsonis P; Department of Medical and Human Genetics, Baylor College of Medicine, Houston, Texas., Lai C; Color Genomics, Burlingame, California., Lichtarge O; Department of Medical and Human Genetics, Baylor College of Medicine, Houston, Texas.; Department of Biochemistry & Molecular Biology, Baylor College of Medicine, Houston, Texas.; Department of Pharmacology, Baylor College of Medicine, Houston, Texas.; Computational and Integrative Biomedical Research Center, Baylor College of Medicine, Houston, Texas., Martelli PL; FaBiT Department, Biocomputing Group, University of Bologna, Bologna, Italy., Mishne G; Color Genomics, Burlingame, California., Moles-Fernández A; Clinical and Translational Bioinformatics Research Unit, Vall d'Hebron Institute of Research (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain., Montalban G; Clinical and Translational Bioinformatics Research Unit, Vall d'Hebron Institute of Research (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain., Mooney SD; Biomedical Informatics and Medical Education, University of Washington, Seattle, Washington., O'Conner R; Sage Bionetworks, Seattle, Washington., Ootes L; Clinical and Translational Bioinformatics Research Unit, Vall d'Hebron Institute of Research (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain., Özkan S; Clinical and Translational Bioinformatics Research Unit, Vall d'Hebron Institute of Research (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain., Padilla N; Clinical and Translational Bioinformatics Research Unit, Vall d'Hebron Institute of Research (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain., Pagel KA; Computer Science and Informatics, Indiana University, Bloomington, Indiana., Pejaver V; Biomedical Informatics and Medical Education, University of Washington, Seattle, Washington., Radivojac P; Computer Science and Informatics, Indiana University, Bloomington, Indiana.; Khoury College of Computer Science, Northeastern University, Boston, Massachusetts., Riera C; Clinical and Translational Bioinformatics Research Unit, Vall d'Hebron Institute of Research (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain., Savojardo C; FaBiT Department, Biocomputing Group, University of Bologna, Bologna, Italy., Shen Y; Department of Electrical and Computer Engineering, Texas A&M University, College Station, Texas., Sun Y; Department of Electrical and Computer Engineering, Texas A&M University, College Station, Texas., Topper S; Color Genomics, Burlingame, California., Parsons MT; Molecular Cancer Epidemiology, QIMR Berghofer Medical Research Institute, Brisbane, Australia., Spurdle AB; Molecular Cancer Epidemiology, QIMR Berghofer Medical Research Institute, Brisbane, Australia., Goldgar DE; Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah.

مؤلفون مشاركون: ENIGMA Consortium

المصدر: Human mutation [Hum Mutat] 2019 Sep; Vol. 40 (9), pp. 1546-1556. Date of Electronic Publication: 2019 Aug 23.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 9215429 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-1004 (Electronic) Linking ISSN: 10597794 NLM ISO Abbreviation: Hum Mutat Subsets: MEDLINE

مواضيع طبية MeSH: BRCA1 Protein/*genetics , BRCA2 Protein/*genetics , Breast Neoplasms/*diagnosis , Computational Biology/*methods , Ovarian Neoplasms/*diagnosis, Breast Neoplasms/genetics ; Early Detection of Cancer ; Female ; Genetic Predisposition to Disease ; Genetic Testing ; Genetic Variation ; Humans ; Models, Genetic ; Ovarian Neoplasms/genetics