المؤلفون: Zhou Z; Tianjin Institute of Immunology, Key Laboratory of Immune Microenvironment and Disease of the Ministry of Education, The Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, Department of Immunology, School of Basic Medical Sciences, Tianjin Medical University General Hospital, Tianjin Medical University, Tianjin 300070. China., Fan H; Department of Chemical Biology, Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics, School of Pharmacy, Tianjin Medical University, Tianjin 300070. China., Yu D; Department of Chemical Biology, Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics, School of Pharmacy, Tianjin Medical University, Tianjin 300070. China., Shi F; Tianjin Institute of Immunology, Key Laboratory of Immune Microenvironment and Disease of the Ministry of Education, The Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, Department of Immunology, School of Basic Medical Sciences, Tianjin Medical University General Hospital, Tianjin Medical University, Tianjin 300070. China., Li Q; Tianjin Institute of Immunology, Key Laboratory of Immune Microenvironment and Disease of the Ministry of Education, The Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, Department of Immunology, School of Basic Medical Sciences, Tianjin Medical University General Hospital, Tianjin Medical University, Tianjin 300070. China., Zhang Z; Tianjin Institute of Immunology, Key Laboratory of Immune Microenvironment and Disease of the Ministry of Education, The Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, Department of Immunology, School of Basic Medical Sciences, Tianjin Medical University General Hospital, Tianjin Medical University, Tianjin 300070. China., Wang X; Tianjin Institute of Immunology, Key Laboratory of Immune Microenvironment and Disease of the Ministry of Education, The Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, Department of Immunology, School of Basic Medical Sciences, Tianjin Medical University General Hospital, Tianjin Medical University, Tianjin 300070. China., Zhang X; Tianjin Institute of Immunology, Key Laboratory of Immune Microenvironment and Disease of the Ministry of Education, The Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, Department of Immunology, School of Basic Medical Sciences, Tianjin Medical University General Hospital, Tianjin Medical University, Tianjin 300070. China., Dong C; Department of Biochemistry and Molecular Biology, Key Laboratory of Immune Microenvironment and Disease (Ministry of Education), The Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, School of Basic Medical Sciences, Tianjin Medical University, Tianjin 300070. China. Electronic address: dongcheng@tmu.edu.cn., Sun H; Department of Chemical Biology, Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics, School of Pharmacy, Tianjin Medical University, Tianjin 300070. China. Electronic address: sunhuabing@tmu.edu.cn., Mi W; Tianjin Institute of Immunology, Key Laboratory of Immune Microenvironment and Disease of the Ministry of Education, The Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, Department of Immunology, School of Basic Medical Sciences, Tianjin Medical University General Hospital, Tianjin Medical University, Tianjin 300070. China. Electronic address: wenyi.mi@tmu.edu.cn.

المصدر: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2023 Dec 15; Vol. 96, pp. 117526. Date of Electronic Publication: 2023 Nov 08.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Science Country of Publication: England NLM ID: 9413298 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3391 (Electronic) Linking ISSN: 09680896 NLM ISO Abbreviation: Bioorg Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Estrogen Receptor alpha*/metabolism , Breast Neoplasms*/pathology, Humans ; Female ; Glutathione/metabolism ; Proteolysis ; Tumor Microenvironment

المؤلفون: Nurmi AK; Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Hospital, Biomedicum Helsinki, P.O. Box 700, 00290, Helsinki, Finland., Pelttari LM; Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Hospital, Biomedicum Helsinki, P.O. Box 700, 00290, Helsinki, Finland., Kiiski JI; Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Hospital, Biomedicum Helsinki, P.O. Box 700, 00290, Helsinki, Finland., Khan S; Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Hospital, Biomedicum Helsinki, P.O. Box 700, 00290, Helsinki, Finland., Nurmikolu M; Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Hospital, Biomedicum Helsinki, P.O. Box 700, 00290, Helsinki, Finland., Suvanto M; Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Hospital, Biomedicum Helsinki, P.O. Box 700, 00290, Helsinki, Finland., Aho N; Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Hospital, Biomedicum Helsinki, P.O. Box 700, 00290, Helsinki, Finland., Tasmuth T; Department of Anaesthesiology, Intensive Care and Pain Medicine, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Kalso E; Department of Anaesthesiology, Intensive Care and Pain Medicine, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Schleutker J; Institute of Biomedicine, University of Turku, and FICAN West Cancer Centre, and Department of Genomics, Laboratory Division, Turku University Hospital, Turku, Finland., Kallioniemi A; Tays Cancer Center, Tampere University Hospital, and BioMediTech Institute and Faculty of Medicine and Health Technology, Tampere University, and Fimlab Laboratories, Tampere, Finland., Heikkilä P; Department of Pathology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Aittomäki K; Department of Clinical Genetics, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Blomqvist C; Department of Oncology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Nevanlinna H; Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Hospital, Biomedicum Helsinki, P.O. Box 700, 00290, Helsinki, Finland. heli.nevanlinna@hus.fi.

مؤلفون مشاركون: FinnGen

المصدر: Scientific reports [Sci Rep] 2023 Nov 30; Vol. 13 (1), pp. 21127. Date of Electronic Publication: 2023 Nov 30.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

مواضيع طبية MeSH: Genetic Predisposition to Disease* , Breast Neoplasms*/genetics, Humans ; Female ; Heterozygote ; Breast ; Finland ; Deoxyribonuclease (Pyrimidine Dimer)/genetics

المؤلفون: Faltinová M; Comprehensive Cancer Center, Helsinki University Hospital, PO Box 180, 00290, Helsinki, Finland.; University of Helsinki, Helsinki, Finland., Vehmanen L; Comprehensive Cancer Center, Helsinki University Hospital, PO Box 180, 00290, Helsinki, Finland.; University of Helsinki, Helsinki, Finland., Lyytinen H; University of Helsinki, Helsinki, Finland., Haanpää M; HUSLAB, Helsinki University Hospital, Helsinki, Finland., Hämäläinen E; University of Helsinki, Helsinki, Finland.; Department of Clinical Chemistry, University of Eastern Finland, Kuopio, Finland., Tiitinen A; University of Helsinki, Helsinki, Finland., Blomqvist C; Comprehensive Cancer Center, Helsinki University Hospital, PO Box 180, 00290, Helsinki, Finland.; University of Helsinki, Helsinki, Finland., Mattson J; Comprehensive Cancer Center, Helsinki University Hospital, PO Box 180, 00290, Helsinki, Finland. johanna.mattson@hus.fi.; University of Helsinki, Helsinki, Finland. johanna.mattson@hus.fi.

المصدر: Breast cancer research and treatment [Breast Cancer Res Treat] 2023 Oct; Vol. 201 (3), pp. 425-435. Date of Electronic Publication: 2023 Jul 25.

نوع المنشور: Clinical Trial; Journal Article

بيانات الدورية: Publisher: Kluwer Academic Country of Publication: Netherlands NLM ID: 8111104 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-7217 (Electronic) Linking ISSN: 01676806 NLM ISO Abbreviation: Breast Cancer Res Treat Subsets: MEDLINE

مواضيع طبية MeSH: Breast Neoplasms*/drug therapy , Estrone*, Female ; Humans ; Chromatography, Liquid/methods ; Estradiol ; Estrogens/therapeutic use ; Letrozole/therapeutic use ; Postmenopause ; Prospective Studies ; Quality of Life ; Tandem Mass Spectrometry/methods

المؤلفون: Devarajan R; Oulu Center for Cell-Matrix Research, Faculty of Biochemistry and Molecular Medicine.; Laboratory of Cancer Genetics and Tumor Biology, Cancer and Translational Medicine Research Unit.; Biocenter Oulu, and., Izzi V; Oulu Center for Cell-Matrix Research, Faculty of Biochemistry and Molecular Medicine.; Research Unit of Biomedicine, University of Oulu, Oulu, Finland.; Finnish Cancer Research Institute, Helsinki, Finland., Peltoketo H; Laboratory of Cancer Genetics and Tumor Biology, Cancer and Translational Medicine Research Unit.; Biocenter Oulu, and., Rask G; Department of Medical Biosciences/Pathology, Umeå University, Umeå, Sweden., Kauppila S; Department of Pathology, Oulu University Hospital and University of Oulu, Oulu, Finland.; Northern Finland Laboratory Centre, NordLab, Oulu, Finland., Väisänen MR; Department of Pathology, Kainuu Central Hospital, Kajaani, Finland., Ruotsalainen H; Oulu Center for Cell-Matrix Research, Faculty of Biochemistry and Molecular Medicine., Martínez-Nieto G; Oulu Center for Cell-Matrix Research, Faculty of Biochemistry and Molecular Medicine., Karppinen SM; Oulu Center for Cell-Matrix Research, Faculty of Biochemistry and Molecular Medicine., Väisänen T; Department of Pathology, Oulu University Hospital and University of Oulu, Oulu, Finland., Kaur I; Oulu Center for Cell-Matrix Research, Faculty of Biochemistry and Molecular Medicine., Koivunen J; Department of Medical Oncology and Radiotherapy and Medical Research Center, Oulu University Hospital and University of Oulu, Oulu, Finland., Sasaki T; Department of Pharmacology, Faculty of Medicine, Oita University, Oita, Japan., Winqvist R; Laboratory of Cancer Genetics and Tumor Biology, Cancer and Translational Medicine Research Unit.; Biocenter Oulu, and.; Northern Finland Laboratory Centre, NordLab, Oulu, Finland., Manninen A; Disease Networks Research Unit, Faculty of Biochemistry and Molecular Medicine, University of Oulu, Oulu, Finland., Wärnberg F; Department of Surgery, Institute of Clinical Sciences, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden., Sund M; Department of Surgery and Perioperative Sciences/Surgery, Umeå University, Umeå, Sweden.; Department of Surgery, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Pihlajaniemi T; Oulu Center for Cell-Matrix Research, Faculty of Biochemistry and Molecular Medicine., Heljasvaara R; Oulu Center for Cell-Matrix Research, Faculty of Biochemistry and Molecular Medicine.

المصدر: The Journal of clinical investigation [J Clin Invest] 2023 Sep 15; Vol. 133 (18). Date of Electronic Publication: 2023 Sep 15.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: Electronic Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE

مواضيع طبية MeSH: Collagen Type XVIII*/metabolism , Breast Neoplasms*/drug therapy , Breast Neoplasms*/genetics , Breast Neoplasms*/metabolism, Mice ; Animals ; Humans ; Female ; Phosphatidylinositol 3-Kinases/metabolism ; Receptor, ErbB-2/metabolism ; Cell Transformation, Neoplastic ; Signal Transduction

المؤلفون: Stolarova L; Laboratory of Cancer Cell Biology, Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czech Republic., Kleiblova P; Institute of Medical Biochemistry and Laboratory Diagnostics, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czech Republic.; Institute of Biology and Medical Genetics, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czech Republic., Zemankova P; Institute of Medical Biochemistry and Laboratory Diagnostics, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czech Republic.; Department of Pathophysiology, First Faculty of Medicine, Charles University, Prague, Czech Republic., Stastna B; Institute of Medical Biochemistry and Laboratory Diagnostics, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czech Republic., Janatova M; Institute of Medical Biochemistry and Laboratory Diagnostics, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czech Republic., Soukupova J; Institute of Medical Biochemistry and Laboratory Diagnostics, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czech Republic., Achatz MI; A.C. Camargo Cancer Center and Oncology Center, Hospital Sirio-Libanes, Sao Paulo, Brazil., Ambrosone C; Department of Cancer Prevention & Control, Roswell Park Cancer Center, Buffalo, New York.; WCHS Inc., Baltimore, Maryland., Apostolou P; Human Molecular Genetics Laboratory, INRaSTES, National Center for Scientific Research 'Demokritos,' Athens, Greece., Arun BK; Department of Breast Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas., Auer P; Division of Biostatistics, Institute for Health and Equity, and Cancer Center, Medical College of Wisconsin, Milwaukee, Wisconsin.; WHI, USA., Barnard M; Slone Epidemiology Center, Boston University, Boston, Massachusetts., Bertelsen B; Center for Genomic Medicine, Copenhagen University Hospital, Copenhagen, Denmark., Blok MJ; Department of Clinical Genetics, Maastricht University Medical Centre, Maastricht, the Netherlands., Boddicker N; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota.; CARRIERS, USA., Brunet J; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain.; Hereditary Cancer Program, Catalan Institute of Oncology, IDIBELL-IGTP-IDIBGI, L'Hospitalet, Barcelona, Spain., Burnside ES; School of Medicine and Public Health, University of Wisconsin, Madison, Wisconsin.; WWHS, Charlotte, North Carolina., Calvello M; Division of Cancer Prevention and Genetics, IEO, European Institute of Oncology, IRCCS, Milan, Italy., Campbell I; Cancer Genomics Laboratory, Peter MacCallum Cancer Centre, Melbourne, Australia.; Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Australia., Chan SH; Cancer Genetics Service, National Cancer Centre, Singapore, Singapore.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore., Chen F; Keck School of Medicine, University of Southern California, Los Angeles, California.; MEC, USA., Chiang JB; Cancer Genetics Service, National Cancer Centre, Singapore, Singapore., Coppa A; Department of Experimental Medicine, Sapienza University of Rome, Rome, Italy., Cortesi L; Department of Oncology and Haematology, Modena University Hospital, Modena, Italy., Crujeiras-González A; Fundacion Publica Galega de Medicina Xenomica, Santiago de Compostela, Spain.; Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), Santiago de Compostela, Spain., De Leeneer K; Center for Medical Genetics, Ghent University and Ghent University Hospital, Ghent, Belgium., De Putter R; Center for Medical Genetics, Ghent University and Ghent University Hospital, Ghent, Belgium., DePersia A; Center for Medical Genetics, NorthShore University Health System, Evanston, Illinois., Devereux L; Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Australia.; Lifepool, Peter MacCallum Cancer Centre, Melbourne, Australia., Domchek S; CARRIERS, USA.; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., Efremidis A; Clinical Cancer Genetics and Family Consultants, CLINICAGENE, Athens Medical Center, Athens, Greece., Engel C; Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany., Ernst C; Center for Familial Breast and Ovarian Cancer, Center for Integrated Oncology (CIO), University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany., Evans DGR; Manchester Centre for Genomic Medicine, Division of Evolution and Genomic Sciences, University of Manchester, Manchester, United Kingdom., Feliubadaló L; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain.; Hereditary Cancer Program, Catalan Institute of Oncology, IDIBELL-IGTP-IDIBGI, L'Hospitalet, Barcelona, Spain., Fostira F; Molecular Diagnostics Laboratory, INRaSTES, National Center for Scientific Research 'Demokritos,' Athens, Greece., Fuentes-Ríos O; Fundacion Publica Galega de Medicina Xenomica, Santiago de Compostela, Spain.; Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), Santiago de Compostela, Spain., Gómez-García EB; Department of Clinical Genetics, Maastricht University Medical Centre, Maastricht, the Netherlands., González S; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain.; Hereditary Cancer Program, Catalan Institute of Oncology, IDIBELL-IGTP-IDIBGI, L'Hospitalet, Barcelona, Spain., Haiman C; Keck School of Medicine, University of Southern California, Los Angeles, California.; MEC, USA., Hansen TVO; Department of Clinical Genetics, Copenhagen University Hospital, Copenhagen, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, Copenhagen University, Copenhagen, Denmark., Hauke J; Center for Familial Breast and Ovarian Cancer, Center for Integrated Oncology (CIO), University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany., Hodge J; Behavioral and Epidemiology Research Group, American Cancer Society, Atlanta, Georgia.; CPS3, Kennesaw, Georgia., Hu C; CARRIERS, USA.; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota., Huang H; T.H. Chan School of Public Health, Harvard University, Cambridge, Massachusetts.; NHS, Reston, Virginia., Ishak NDB; Cancer Genetics Service, National Cancer Centre, Singapore, Singapore., Iwasaki Y; Laboratory for Genotyping Development, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan., Konstantopoulou I; Molecular Diagnostics Laboratory, INRaSTES, National Center for Scientific Research 'Demokritos,' Athens, Greece., Kraft P; T.H. Chan School of Public Health, Harvard University, Cambridge, Massachusetts.; NHS, Reston, Virginia., Lacey J; Beckman Research Institute, City of Hope Cancer Center, Duarte, California.; CTS, USA., Lázaro C; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain.; Hereditary Cancer Program, Catalan Institute of Oncology, IDIBELL-IGTP-IDIBGI, L'Hospitalet, Barcelona, Spain., Li N; Cancer Genomics Laboratory, Peter MacCallum Cancer Centre, Melbourne, Australia., Lim WK; Duke-NUS Medical School, Singapore, Singapore., Lindstrom S; WHI, USA.; Department of Epidemiology, University of Washington, Seattle, Washington., Lori A; Behavioral and Epidemiology Research Group, American Cancer Society, Atlanta, Georgia.; American Cancer Society, Atlanta, Georgia., Martinez E; Duke-NUS Medical School, Singapore, Singapore.; Department of Family Medicine and Public Health, University of California San Diego, San Diego, California., Martins A; Inserm UMR1245, UNIROUEN, Normandy Centre for Genomic and Personalized Medicine, Normandie University, Rouen, France., Matsuda K; Institute of Medical Science, The University of Tokyo, Tokyo, Japan., Matullo G; Department of Medical Sciences, University of Turin, Turin, Italy., McInerny S; Parkville Familial Cancer Centre, Peter MacCallum Cancer Centre, and Royal Melbourne Hospital, Melbourne, Australia., Michailidou K; Biostatistics Unit, The Cyprus Institute of Neurology and Genetics, Nicosia, Cyprus., Montagna M; Immunology and Molecular Oncology Unit, Veneto Institute of Oncology, Padua, Italy., Monteiro ANA; Cancer Epidemiology Program, Division of Population Sciences, H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida., Mori L; Endocrine and Metabolic Disease Unit, ASST Spedali Civili of Brescia, Brescia, Italia.; Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy., Nathanson K; CARRIERS, USA.; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., Neuhausen SL; Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, California., Nevanlinna H; Department of Obstetrics and Gynecology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland., Olson JE; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota.; MCBCS, USA., Palmer J; Slone Epidemiology Center, Boston University, Boston, Massachusetts., Pasini B; Department of Medical Sciences, University of Turin, Turin, Italy., Patel A; Department of Population Science, American Cancer Society, Atlanta, Georgia.; CPS-II, USA., Piane M; Department of Clinical and Molecular Medicine, Sapienza University of Rome, Rome, Italy., Poppe B; Center for Medical Genetics, Ghent University and Ghent University Hospital, Ghent, Belgium., Radice P; Department of Experimental Oncology, Molecular Bases of Genetic Risk and Genetic Testing Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Renieri A; Medical genetics, University of Siena, Siena, Italy., Resta N; Department of Precision and Regenerative Medicine and Ionian Area, Medical Genetics Unit, University of Bari, Bari, Italy., Richardson ME; Ambry Genetics, Aliso Viejo, California., Rosseel T; Center for Medical Genetics, Ghent University and Ghent University Hospital, Ghent, Belgium., Ruddy KJ; MCBCS, USA.; Department of Oncology, Mayo Clinic, Rochester, Minnesota., Santamariña M; Fundacion Publica Galega de Medicina Xenomica, Santiago de Compostela, Spain.; Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), Santiago de Compostela, Spain.; Centro de Investigación en Red de Enfermedades Raras (CIBERER), Santiago de Compostela, Spain., Dos Santos ES; A.C. Camargo Cancer Center and Oncology Center, Hospital Sirio-Libanes, Sao Paulo, Brazil., Teras L; Department of Population Science, American Cancer Society, Atlanta, Georgia.; CPS-II, USA., Toland AE; Department of Cancer Biology & Genetics, Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio., Trentham-Dietz A; WWHS, Charlotte, North Carolina.; University of Wisconsin, Madison, Wisconsin., Vachon CM; Mayo Clinic, Rochester, Minnesota.; MMHS, USA., Volk AE; Institute of Human Genetics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Weber-Lassalle N; Center for Familial Breast and Ovarian Cancer, Center for Integrated Oncology (CIO), University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany., Weitzel JN; CARRIERS, USA.; Natera Inc., Duarte, California., Wiesmuller L; Department of Obstetrics and Gynecology, Ulm University, Ulm, Germany., Winham S; MMHS, USA.; Department Quantitative Sciences, Mayo Clinic, Rochester, Minnesota., Yadav S; CARRIERS, USA.; Department of Medical Oncology, Mayo Clinic, Rochester, Minnesota., Yannoukakos D; Molecular Diagnostics Laboratory, INRaSTES, National Center for Scientific Research 'Demokritos,' Athens, Greece., Yao S; WCHS Inc., Baltimore, Maryland.; Roswell Park Comprehensive Cancer Center, Buffalo, New York., Zampiga V; Biosciences Laboratory, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) 'Dino Amadori,' Meldola, Italy., Zethoven M; Cancer Genomics Laboratory, Peter MacCallum Cancer Centre, Melbourne, Australia., Zhang ZW; Cancer Genetics Service, National Cancer Centre, Singapore, Singapore., Zima T; Institute of Medical Biochemistry and Laboratory Diagnostics, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czech Republic., Spurdle AB; Population Health Program, QIMR Berghofer Medical Research Institute, Brisbane, Australia., Vega A; Fundacion Publica Galega de Medicina Xenomica, Santiago de Compostela, Spain.; Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), Santiago de Compostela, Spain.; Centro de Investigación en Red de Enfermedades Raras (CIBERER), Santiago de Compostela, Spain., Rossing M; Center for Genomic Medicine, Copenhagen University Hospital, Copenhagen, Denmark., Del Valle J; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain.; Hereditary Cancer Program, Catalan Institute of Oncology, IDIBELL-IGTP-IDIBGI, L'Hospitalet, Barcelona, Spain., De Nicolo A; Center for Omics Sciences, IRCCS San Raffaele Scientific Institute, Milan, Italy., Hahnen E; Center for Familial Breast and Ovarian Cancer, Center for Integrated Oncology (CIO), University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany., Claes KBM; Center for Medical Genetics, Ghent University and Ghent University Hospital, Ghent, Belgium., Ngeow J; Cancer Genetics Service, National Cancer Centre, Singapore, Singapore.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore., Momozawa Y; Laboratory for Genotyping Development, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan., James PA; Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Australia.; Inserm UMR1245, UNIROUEN, Normandy Centre for Genomic and Personalized Medicine, Normandie University, Rouen, France., Couch FJ; CARRIERS, USA.; Behavioral and Epidemiology Research Group, American Cancer Society, Atlanta, Georgia., Macurek L; Laboratory of Cancer Cell Biology, Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czech Republic., Kleibl Z; Institute of Medical Biochemistry and Laboratory Diagnostics, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czech Republic.; Department of Pathophysiology, First Faculty of Medicine, Charles University, Prague, Czech Republic.

مؤلفون مشاركون: Biobank Japan, Consortium CZECANCA

المصدر: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2023 Aug 15; Vol. 29 (16), pp. 3037-3050.

نوع المنشور: Meta-Analysis; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: The Association Country of Publication: United States NLM ID: 9502500 Publication Model: Print Cited Medium: Internet ISSN: 1557-3265 (Electronic) Linking ISSN: 10780432 NLM ISO Abbreviation: Clin Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: Breast Neoplasms*/epidemiology , Breast Neoplasms*/genetics, Humans ; Female ; Genetic Predisposition to Disease ; Checkpoint Kinase 2/genetics ; Mutation, Missense ; Germ-Line Mutation ; Germ Cells

المؤلفون: Morra A; Division of Molecular Pathology, The Netherlands Cancer Institute, Amsterdam, the Netherlands., Schreurs MAC; Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, the Netherlands., Andrulis IL; Fred A. Litwin Center for Cancer Genetics, Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Ontario, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada., Anton-Culver H; Department of Medicine, Genetic Epidemiology Research Institute, University of California Irvine, Irvine, California, USA., Augustinsson A; Oncology, Clinical Sciences in Lund, Lund University, Lund, Sweden., Beckmann MW; Department of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen-EMN, Friedrich-Alexander University Erlangen-Nuremberg, University Hospital Erlangen, Erlangen, Germany., Behrens S; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany., Bojesen SE; Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.; Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Bolla MK; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Brauch H; Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Germany.; iFIT-Cluster of Excellence, University of Tübingen, Tübingen, Germany.; German Cancer Consortium (DKTK), Partner Site Tübingen, German Cancer Research Center (DKFZ), Tübingen, Germany., Broeks A; Division of Molecular Pathology, The Netherlands Cancer Institute, Amsterdam, the Netherlands., Buys SS; Department of Internal Medicine and Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah, USA., Camp NJ; Department of Internal Medicine and Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah, USA., Castelao JE; Oncology and Genetics Unit, Instituto de Investigación Sanitaria Galicia Sur (IISGS), Xerencia de Xestion Integrada de Vigo-SERGAS, Vigo, Spain., Cessna MH; Intermountain Healthcare, Salt Lake City, Utah, USA., Chang-Claude J; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Cancer Epidemiology Group, University Cancer Center Hamburg (UCCH), University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Chung WK; Departments of Pediatrics and Medicine, Columbia University, New York, New York, USA., Colonna SV; Department of Internal Medicine and Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah, USA., Couch FJ; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA., Cox A; Department of Oncology and Metabolism, Sheffield Institute for Nucleic Acids (SInFoNiA), University of Sheffield, Sheffield, UK., Cross SS; Department of Neuroscience, Academic Unit of Pathology, University of Sheffield, Sheffield, UK., Czene K; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Daly MB; Department of Clinical Genetics, Fox Chase Cancer Center, Philadelphia, Pennsylvania, USA., Dennis J; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Devilee P; Department of Pathology, Leiden University Medical Center, Leiden, the Netherlands.; Department of Human Genetics, Leiden University Medical Center, Leiden, the Netherlands., Dörk T; Gynaecology Research Unit, Hannover Medical School, Hannover, Germany., Dunning AM; Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, UK., Dwek M; School of Life Sciences, University of Westminster, London, UK., Easton DF; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, UK., Eccles DM; Faculty of Medicine, University of Southampton, Southampton, UK., Eriksson M; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Evans DG; Division of Evolution and Genomic Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.; North West Genomics Laboratory Hub, Manchester Centre for Genomic Medicine, St Mary's Hospital, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK., Fasching PA; Department of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen-EMN, Friedrich-Alexander University Erlangen-Nuremberg, University Hospital Erlangen, Erlangen, Germany., Fehm TN; Department of Gynecology and Obstetrics, University Hospital Düsseldorf, Heinrich-Heine University Düsseldorf, Düsseldorf, Germany., Figueroa JD; Usher Institute of Population Health Sciences and Informatics, The University of Edinburgh, Edinburgh, UK.; Cancer Research UK Edinburgh Centre, The University of Edinburgh, Edinburgh, UK.; Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA., Flyger H; Department of Breast Surgery, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark., Gabrielson M; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Gago-Dominguez M; Cancer Genetics and Epidemiology Group, SERGAS, Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS) Foundation, Complejo Hospitalario Universitario de Santiago, Santiago de Compostela, Spain., García-Closas M; Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA., García-Sáenz JA; Medical Oncology Department, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria San Carlos (IdISSC), Centro Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain., Genkinger J; Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York, USA.; Herbert Irving Comprehensive Cancer Center, New York, New York, USA., Grassmann F; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.; Health and Medical University, Potsdam, Germany., Gündert M; Molecular Epidemiology Group, C080, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Molecular Biology of Breast Cancer, University Womens Clinic Heidelberg, University of Heidelberg, Heidelberg, Germany.; Institute of Diabetes Research, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany., Hahnen E; Center for Familial Breast and Ovarian Cancer, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; Center for Integrated Oncology (CIO), Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany., Haiman CA; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA., Hamann U; Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany., Harrington PA; Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, UK., Hartikainen JM; Translational Cancer Research Area, University of Eastern Finland, Kuopio, Finland.; Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland, Kuopio, Finland., Hoppe R; Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Germany.; University of Tübingen, Tübingen, Germany., Hopper JL; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia., Houlston RS; Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK., Howell A; Division of Cancer Sciences, University of Manchester, Manchester, UK., Jakubowska A; Department of Genetics and Pathology, International Hereditary Cancer Center, Pomeranian Medical University, Szczecin, Poland.; Independent Laboratory of Molecular Biology and Genetic Diagnostics, Pomeranian Medical University, Szczecin, Poland., Janni W; Department of Gynaecology and Obstetrics, University Hospital Ulm, Ulm, Germany., Jernström H; Oncology, Clinical Sciences in Lund, Lund University, Lund, Sweden., John EM; Department of Epidemiology and Population Health, Stanford University School of Medicine, Stanford, California, USA.; Division of Oncology, Department of Medicine, Stanford Cancer Institute, Stanford University School of Medicine, Stanford, California, USA., Johnson N; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK., Jones ME; Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK., Kristensen VN; Faculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Department of Medical Genetics, Oslo University Hospital and University of Oslo, Oslo, Norway., Kurian AW; Department of Epidemiology and Population Health, Stanford University School of Medicine, Stanford, California, USA.; Division of Oncology, Department of Medicine, Stanford Cancer Institute, Stanford University School of Medicine, Stanford, California, USA., Lambrechts D; Laboratory for Translational Genetics, Department of Human Genetics, KU Leuven, Leuven, Belgium.; VIB Center for Cancer Biology, VIB, Leuven, Belgium., Le Marchand L; Epidemiology Program, University of Hawaii Cancer Center, Honolulu, Hawaii, USA., Lindblom A; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.; Department of Clinical Genetics, Karolinska University Hospital, Stockholm, Sweden., Lubiński J; Department of Genetics and Pathology, International Hereditary Cancer Center, Pomeranian Medical University, Szczecin, Poland., Lux MP; Department of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen-EMN, Friedrich-Alexander University Erlangen-Nuremberg, University Hospital Erlangen, Erlangen, Germany., Mannermaa A; Translational Cancer Research Area, University of Eastern Finland, Kuopio, Finland.; Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland, Kuopio, Finland.; Biobank of Eastern Finland, Kuopio University Hospital, Kuopio, Finland., Mavroudis D; Department of Medical Oncology, University Hospital of Heraklion, Heraklion, Greece., Mulligan AM; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.; Laboratory Medicine Program, University Health Network, Toronto, Ontario, Canada., Muranen TA; Department of Obstetrics and Gynecology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland., Nevanlinna H; Department of Obstetrics and Gynecology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland., Nevelsteen I; Department of Oncology, Leuven Multidisciplinary Breast Center, University Hospitals Leuven, Leuven Cancer Institute, Leuven, Belgium., Neven P; Department of Oncology, Leuven Multidisciplinary Breast Center, University Hospitals Leuven, Leuven Cancer Institute, Leuven, Belgium., Newman WG; Division of Evolution and Genomic Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.; North West Genomics Laboratory Hub, Manchester Centre for Genomic Medicine, St Mary's Hospital, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK., Obi N; Institute for Medical Biometry and Epidemiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Offit K; Clinical Genetics Research Lab, Department of Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, New York, USA.; Clinical Genetics Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA., Olshan AF; Department of Epidemiology, Gillings School of Global Public Health and UNC Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Park-Simon TW; Gynaecology Research Unit, Hannover Medical School, Hannover, Germany., Patel AV; Department of Population Science, American Cancer Society, Atlanta, Georgia, USA., Peterlongo P; IFOM ETS - The AIRC Institute of Molecular Oncology, Genome Diagnostics Program, Milan, Italy., Phillips KA; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia.; Department of Medical Oncology, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia., Plaseska-Karanfilska D; Research Centre for Genetic Engineering and Biotechnology 'Georgi D. Efremov', MASA, Skopje, Republic of North Macedonia., Polley EC; Division of Clinical Trials and Biostatistics, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, USA., Presneau N; School of Life Sciences, University of Westminster, London, UK., Pylkäs K; Laboratory of Cancer Genetics and Tumor Biology, Cancer and Translational Medicine Research Unit, Biocenter Oulu, University of Oulu, Oulu, Finland.; Laboratory of Cancer Genetics and Tumor Biology, Northern Finland Laboratory Centre Oulu, Oulu, Finland., Rack B; Department of Gynaecology and Obstetrics, University Hospital Ulm, Ulm, Germany., Radice P; Department of Experimental Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, 'Predictive Medicine: Molecular Bases of Genetic Risk', Milan, Italy., Rashid MU; Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Basic Sciences, Shaukat Khanum Memorial Cancer Hospital and Research Centre (SKMCH & RC), Lahore, Pakistan., Rhenius V; Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, UK., Robson M; Clinical Genetics Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA., Romero A; Medical Oncology Department, Hospital Universitario Puerta de Hierro, Madrid, Spain., Saloustros E; Department of Oncology, University Hospital of Larissa, Larissa, Greece., Sawyer EJ; School of Cancer & Pharmaceutical Sciences, Comprehensive Cancer Centre, Guy's Campus, King's College London, London, UK., Schmutzler RK; Center for Familial Breast and Ovarian Cancer, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; Center for Integrated Oncology (CIO), Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; Center for Molecular Medicine Cologne (CMMC), Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany., Schuetze S; Department of Gynaecology and Obstetrics, University Hospital Ulm, Ulm, Germany., Scott C; Division of Clinical Trials and Biostatistics, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, USA., Shah M; Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, UK., Smichkoska S; Medical Faculty, University Clinic of Radiotherapy and Oncology, Ss. Cyril and Methodius University in Skopje, Skopje, Republic of North Macedonia., Southey MC; Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, Victoria, Australia.; Department of Clinical Pathology, The University of Melbourne, Melbourne, Victoria, Australia.; Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, Victoria, Australia., Tapper WJ; Faculty of Medicine, University of Southampton, Southampton, UK., Teras LR; Department of Population Science, American Cancer Society, Atlanta, Georgia, USA., Tollenaar RAEM; Department of Surgery, Leiden University Medical Center, Leiden, the Netherlands., Tomczyk K; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK., Tomlinson I; Cancer Research Centre, The University of Edinburgh, Edinburgh, UK., Troester MA; Department of Epidemiology, Gillings School of Global Public Health and UNC Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Vachon CM; Division of Epidemiology, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, USA., van Veen EM; Division of Evolution and Genomic Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.; North West Genomics Laboratory Hub, Manchester Centre for Genomic Medicine, St Mary's Hospital, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK., Wang Q; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Wendt C; Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden.; Department of Oncology, Södersjukhuset, Stockholm, Sweden., Wildiers H; Department of Oncology, Leuven Multidisciplinary Breast Center, University Hospitals Leuven, Leuven Cancer Institute, Leuven, Belgium., Winqvist R; Laboratory of Cancer Genetics and Tumor Biology, Cancer and Translational Medicine Research Unit, Biocenter Oulu, University of Oulu, Oulu, Finland.; Laboratory of Cancer Genetics and Tumor Biology, Northern Finland Laboratory Centre Oulu, Oulu, Finland., Ziogas A; Department of Medicine, Genetic Epidemiology Research Institute, University of California Irvine, Irvine, California, USA., Hall P; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.; Department of Oncology, Södersjukhuset, Stockholm, Sweden., Pharoah PDP; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, UK., Adank MA; Family Cancer Clinic, The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, the Netherlands., Hollestelle A; Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, the Netherlands., Schmidt MK; Division of Molecular Pathology, The Netherlands Cancer Institute, Amsterdam, the Netherlands.; Division of Psychosocial Research and Epidemiology, The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, the Netherlands., Hooning MJ; Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, the Netherlands.

مؤلفون مشاركون: NBCS Collaborators; Department of Cancer Genetics, Institute for Cancer Research, Oslo University Hospital-Radiumhospitalet, Oslo, Norway.; Faculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Department of Research, Vestre Viken Hospital, Drammen, Norway.; Department of Tumor Biology, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway.; Division of Surgery, Cancer and Transplantation Medicine, Department of Oncology, Oslo University Hospital-Radiumhospitalet, Oslo, Norway.; Department of Oncology, Akershus University Hospital, Lørenskog, Norway.; Oslo Breast Cancer Research Consortium, Oslo University Hospital, Oslo, Norway.; Department of Medical Genetics, Oslo University Hospital and University of Oslo, Oslo, Norway.; Department of Community Medicine, The Arctic University of Norway, Tromsø, Norway.; Core Facility for Biobanking, The Arctic University of Norway, Tromsø, Norway., ABCTB Investigators; Australian Breast Cancer Tissue Bank, Westmead Institute for Medical Research, University of Sydney, Sydney, New South Wales, Australia., kConFab Investigators; Research Department, Peter MacCallum Cancer Center, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, Victoria, Australia.

المصدر: Cancer medicine [Cancer Med] 2023 Aug; Vol. 12 (15), pp. 16142-16162. Date of Electronic Publication: 2023 Jul 03.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Intramural; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: John Wiley & Sons Ltd Country of Publication: United States NLM ID: 101595310 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2045-7634 (Electronic) Linking ISSN: 20457634 NLM ISO Abbreviation: Cancer Med Subsets: MEDLINE

مواضيع طبية MeSH: Breast Neoplasms*/genetics , Breast Neoplasms*/radiotherapy, Female ; Humans ; Checkpoint Kinase 2/genetics ; Genetic Predisposition to Disease ; Germ-Line Mutation ; Heterozygote ; Proportional Hazards Models

المؤلفون: O'Mahony DG; Biostatistics Unit, The Cyprus Institute of Neurology and Genetics, Nicosia, 2371, Cyprus.; Department of Cancer Genetics, Therapeutics and Ultrastructural Pathology, The Cyprus Institute of Neurology and Genetics, Nicosia, 2371, Cyprus., Ramus SJ; School of Clinical Medicine, University of New South Wales Medicine and Health, University of New South Wales Sydney, Sydney, NSW, 2052, Australia.; Adult Cancer Program, Lowy Cancer Research Centre, University of New South Wales Sydney, Sydney, NSW, 2052, Australia., Southey MC; Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, 3168, Australia.; Department of Clinical Pathology, The University of Melbourne, Melbourne, VIC, 3010, Australia.; Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, VIC, 3004, Australia., Meagher NS; School of Clinical Medicine, University of New South Wales Medicine and Health, University of New South Wales Sydney, Sydney, NSW, 2052, Australia.; Adult Cancer Program, Lowy Cancer Research Centre, University of New South Wales Sydney, Sydney, NSW, 2052, Australia.; The Daffodil Centre, The University of Sydney, a joint venture with Cancer Council NSW, Sydney, NSW, Australia., Hadjisavvas A; Department of Cancer Genetics, Therapeutics and Ultrastructural Pathology, The Cyprus Institute of Neurology and Genetics, Nicosia, 2371, Cyprus., John EM; Department of Epidemiology and Population Health, Stanford University School of Medicine, Stanford, CA, 94305, USA.; Department of Medicine, Division of Oncology, Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA, 94304, USA., Hamann U; Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, 69120, Germany., Imyanitov EN; N.N. Petrov Institute of Oncology, St. Petersburg, 197758, Russia., Andrulis IL; Fred A. Litwin Center for Cancer Genetics, Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, ON, M5G 1×5, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, ON, M5S 1A8, Canada., Sharma P; Department of Internal Medicine, Division of Medical Oncology, University of Kansas Medical Center, Westwood, KS, 66205, USA., Daly MB; Department of Clinical Genetics, Fox Chase Cancer Center, Philadelphia, PA, 19111, USA., Hake CR; Waukesha Memorial Hospital-Pro Health Care, Waukesha, WI, 53188, USA., Weitzel JN; The University of Kansas Cancer Center, Kansas City, MO, 66160, USA., Jakubowska A; Department of Genetics and Pathology, International Hereditary Cancer Center, Pomeranian Medical University, Szczecin, 171-252, Poland.; Independent Laboratory of Molecular Biology and Genetic Diagnostics, Pomeranian Medical University, Szczecin, 171-252, Poland., Godwin AK; Department of Pathology and Laboratory Medicine, The University of Kansas Medical Center, Kansas City, KS, 66160, USA., Arason A; Department of Pathology, Landspitali University Hospital, Reykjavik, 101, Iceland.; BMC (Biomedical Centre), Faculty of Medicine, University of Iceland, Reykjavik, 101, Iceland., Bane A; Department of Pathology & Molecular Medicine, Juravinski Hospital and Cancer Centre, McMaster University, Hamilton, ON, L8V 1C3, Canada., Simard J; Genomics Center, Centre Hospitalier Universitaire de Québec - Université Laval Research Center, Québec City, QC, G1V 4G2, Canada., Soucy P; Genomics Center, Centre Hospitalier Universitaire de Québec - Université Laval Research Center, Québec City, QC, G1V 4G2, Canada., Caligo MA; SOD Genetica Molecolare, University Hospital, Pisa, 56126, Italy., Mai PL; Magee-Womens Hospital, University of Pittsburgh School of Medicine, Pittsburgh, PA, 15213, USA., Claes KBM; Centre for Medical Genetics, Ghent University, Gent, 9000, Belgium., Teixeira MR; Department of Laboratory Genetics, Portuguese Oncology Institute of Porto (IPO Porto)/Comprehensive Cancer Center, Porto, 4200-072, Portugal.; School of Medicine and Biomedical Sciences Institute (ICBAS), University of Porto, Porto, 4050-013, Portugal., Chung WK; Departments of Pediatrics and Medicine, Columbia University, New York, NY, 10032, USA., Lazaro C; Hereditary Cancer Program, ONCOBELL-IDIBELL-IGTP, Catalan Institute of Oncology, CIBERONC, Barcelona, 08908, Spain., Hulick PJ; Center for Medical Genetics, NorthShore University HealthSystem, Evanston, IL, 60201, USA.; The University of Chicago Pritzker School of Medicine, Chicago, IL, 60637, USA., Toland AE; Department of Cancer Biology and Genetics, The Ohio State University, Columbus, OH, 43210, USA., Pedersen IS; Molecular Diagnostics, Aalborg University Hospital, Aalborg, 9000, Denmark.; Clinical Cancer Research Center, Aalborg University Hospital, Aalborg, 9000, Denmark.; Department of Clinical Medicine, Aalborg University, Aalborg, 9000, Denmark., Neuhausen SL; Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, CA, 91010, USA., Vega A; Centro de Investigación en Red de Enfermedades Raras (CIBERER), Madrid, 28029, Spain.; Fundación Pública Galega de Medicina Xenómica, Santiago de Compostela, 15706, Spain.; Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), Complejo Hospitalario Universitario de Santiago, SERGAS, Santiago de Compostela, 15706, Spain., de la Hoya M; Molecular Oncology Laboratory, CIBERONC, Hospital Clinico San Carlos, IdISSC (Instituto de Investigación Sanitaria del Hospital Clínico San Carlos), Madrid, 28040, Spain., Nevanlinna H; Department of Obstetrics and Gynecology, Helsinki University Hospital, University of Helsinki, Helsinki, 00290, Finland., Dhawan M; Cancer Genetics and Prevention Program, University of California San Francisco, San Francisco, CA, 94143-1714, USA., Zampiga V; Biosciences Laboratory, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) 'Dino Amadori', Meldola, Italy., Danesi R; Romagna Cancer Registry, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) 'Dino Amadori', Meldola, 47014, Italy., Varesco L; Unit of Hereditary Cancer, IRCCS Ospedale Policlinico San Martino, Genoa, 16132, Italy., Gismondi V; Unit of Hereditary Cancer, IRCCS Ospedale Policlinico San Martino, Genoa, 16132, Italy., Vellone VG; Unit of Pathology, IRCCS Ospedale Policlinico San Martino, Genoa, 16132, Italy., James PA; Department of Gynecology and Obstetrics, Ribeirao Preto Medical School, University of Sao Paulo, Ribeirao Preto, 14049-900, Brazil., Janavicius R; Faculty of Medicine, Institute of Biomedical Sciences, Department of Human and Medical Genetics, Vilnius University, Vilnius, LT-03101, Lithuania.; State Research Institute Centre for Innovative Medicine, Vilnius, 8410, Lithuania., Nikitina-Zake L; Latvian Biomedical Research and Study Centre, Riga, LV-1067, Latvia., Nielsen FC; Center for Genomic Medicine, Rigshospitalet, Copenhagen University Hospital, Copenhagen, DK-2100, Denmark., van Overeem Hansen T; Department of Clinical Genetics, Rigshospitalet, Copenhagen University Hospital, Copenhagen, DK-2100, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, , University of Copenhagen, Copenhagen, 2200, Denmark., Pejovic T; Department of Obstetrics and Gynecology, Oregon Health & Science University, Portland, OR, 97239, USA.; Knight Cancer Institute, Oregon Health & Science University, Portland, OR, 97239, USA., Borg A; Department of Oncology, Lund University and Skåne University Hospital, Lund, 222 41, Sweden., Rantala J; Clinical Genetics, Karolinska Institutet, Stockholm, 171 76, Sweden., Offit K; Clinical Genetics Research Lab, Department of Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA.; Clinical Genetics Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Montagna M; Immunology and Molecular Oncology Unit, Veneto Institute of Oncology IOV - IRCCS, Padua, 35128, Italy., Nathanson KL; Basser Center for BRCA, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, 19066, USA., Domchek SM; Basser Center for BRCA, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, 19066, USA., Osorio A; Human Genetics Group, Spanish National Cancer Research Centre (CNIO), Madrid, 28029, Spain.; Centre for Biomedical Network Research on Rare Diseases (CIBERER), Instituto de Salud Carlos III, Madrid, 28029, Spain.; Genetics Service, Fundación Jiménez Díaz, Madrid, 28040, Spain., García MJ; Computational Oncology Group, Structural Biology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, 28029, Spain., Karlan BY; David Geffen School of Medicine, Department of Obstetrics and Gynecology, University of California at Los Angeles, Los Angeles, CA, 90095, USA., De Fazio A; The Daffodil Centre, The University of Sydney, a joint venture with Cancer Council NSW, Sydney, NSW, Australia.; Centre for Cancer Research, The Westmead Institute for Medical Research, Sydney, Australia.; Department of Gynaecological Oncology, Westmead Hospital, Sydney, NSW, 2145, Australia.; The University of Sydney, Sydney, NSW, 2145, Australia., Bowtell D; Peter MacCallum Cancer Centre, Melbourne, VIC, 3000, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, VIC, 3000, Australia., McGuffog L; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK., Leslie G; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK., Parsons MT; Population Health Program, QIMR Berghofer Medical Research Institute, Brisbane, QLD, 4006, Australia., Dörk T; Gynaecology Research Unit, Hannover Medical School, Hannover, 30625, Germany., Speith LM; Gynaecology Research Unit, Hannover Medical School, Hannover, 30625, Germany., Dos Santos ES; Service de Génétique, Institut Curie, Paris, 75005, France.; Oncology Center, Hospital Sirio-Libanes, São Paulo, 01308-050, Brazil.; Department of Clinical Oncology, A.C.Camargo Cancer Center, São Paulo, 1509900, Brazil., da Costa AABA; Department of Clinical Oncology, A.C.Camargo Cancer Center, São Paulo, 1509900, Brazil.; Department of Radiation Oncology, Dana-Farber Cancer Institute, Boston, MA, 2215, USA., Radice P; Unit of Preventive Medicine: Molecular Bases of Genetic Risk, Department of Experimental Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori (INT), Milan, 20133, Italy., Peterlongo P; Genome Diagnostics Program, IFOM ETS - the AIRC Institute of Molecular Oncology, Milan, 20139, Italy., Papi L; Department of Experimental and Clinical Biomedical Sciences 'Mario Serio', Medical Genetics Unit, University of Florence, Florence, 27571, Italy., Engel C; Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, 04107, Germany.; LIFE - Leipzig Research Centre for Civilization Diseases, University of Leipzig, Leipzig, 04103, Germany., Hahnen E; Center for Familial Breast and Ovarian Cancer, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, 50937, Germany.; Center for Integrated Oncology (CIO), Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, 50937, Germany., Schmutzler RK; Center for Familial Breast and Ovarian Cancer, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, 50937, Germany.; Center for Integrated Oncology (CIO), Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, 50937, Germany.; Center for Molecular Medicine Cologne (CMMC), Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, 50931, Germany., Wappenschmidt B; Center for Familial Breast and Ovarian Cancer, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, 50937, Germany.; Center for Integrated Oncology (CIO), Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, 50937, Germany., Easton DF; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK.; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, CB1 8RN, UK., Tischkowitz M; Program in Cancer Genetics, Departments of Human Genetics and Oncology, McGill University, Montréal, QC, H4A 3J1, Canada.; Department of Medical Genetics, National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge, Cambridge, CB2 0QQ, UK., Singer CF; Department of OB/GYN and Comprehensive Cancer Center, Medical University of Vienna, Vienna, 1090, Austria., Tan YY; Department of OB/GYN and Comprehensive Cancer Center, Medical University of Vienna, Vienna, 1090, Austria., Whittemore AS; Department of Epidemiology and Population Health, Stanford University School of Medicine, Stanford, CA, 94305, USA.; Department of Biomedical Data Science, Stanford University School of Medicine, Stanford, CA, 94305, USA., Sieh W; Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA., Brenton JD; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, CB2 0RE, UK., Yannoukakos D; Molecular Diagnostics Laboratory, INRASTES, National Centre for Scientific Research 'Demokritos', Athens, 15310, Greece., Fostira F; Molecular Diagnostics Laboratory, INRASTES, National Centre for Scientific Research 'Demokritos', Athens, 15310, Greece., Konstantopoulou I; Molecular Diagnostics Laboratory, INRASTES, National Centre for Scientific Research 'Demokritos', Athens, 15310, Greece., Soukupova J; Institute of Medical Biochemistry and Laboratory Diagnostics, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, 12000, Czech Republic., Vocka M; Department of Oncology, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, 12000, Czech Republic., Chenevix-Trench G; Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, QLD, 4006, Australia., Pharoah PDP; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK.; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, CB1 8RN, UK., Antoniou AC; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK., Goldgar DE; Department of Dermatology, Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, UT, 84112, USA., Spurdle AB; Population Health Program, QIMR Berghofer Medical Research Institute, Brisbane, QLD, 4006, Australia., Michailidou K; Biostatistics Unit, The Cyprus Institute of Neurology and Genetics, Nicosia, 2371, Cyprus. kyriakimi@cing.ac.cy.; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK. kyriakimi@cing.ac.cy.

مؤلفون مشاركون: HEBON Investigators, GEMO Study Collaborators, AOCS Group, CZECANCA Consortium, Consortium of Investigators of Modifiers of BRCA1/2, Evidence-based Network for the Interpretation of Germline Mutant Alleles Consortium

المصدر: British journal of cancer [Br J Cancer] 2023 Jun; Vol. 128 (12), pp. 2283-2294. Date of Electronic Publication: 2023 Apr 19.

نوع المنشور: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group on behalf of Cancer Research UK Country of Publication: England NLM ID: 0370635 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-1827 (Electronic) Linking ISSN: 00070920 NLM ISO Abbreviation: Br J Cancer Subsets: MEDLINE

مواضيع طبية MeSH: Ovarian Neoplasms*/genetics , Breast Neoplasms*, Humans ; Female ; Virulence ; BRCA1 Protein/genetics ; BRCA2 Protein/genetics ; Genetic Predisposition to Disease

المؤلفون: Figlioli G; IFOM ETS - The AIRC Institute of Molecular Oncology, Genome Diagnostics Program, Milan, Italy., Billaud A; IFOM ETS - The AIRC Institute of Molecular Oncology, Genome Diagnostics Program, Milan, Italy., Ahearn TU; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA., Antonenkova NN; N.N. Alexandrov Research Institute of Oncology and Medical Radiology, Minsk, Belarus., Becher H; University Medical Center Hamburg-Eppendorf, Institute of Medical Biometry and Epidemiology, Hamburg, Germany., Beckmann MW; University Hospital Erlangen, Department of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen-EMN, Friedrich-Alexander University Erlangen-Nuremberg, Erlangen, Germany., Behrens S; German Cancer Research Center (DKFZ), Division of Cancer Epidemiology, Heidelberg, Germany., Benitez J; Spanish National Cancer Research Centre (CNIO), Human Genetics Group, Madrid, Spain.; Centre for Biomedical Network Research on Rare Diseases (CIBERER), Instituto de Salud Carlos III, Madrid, Spain., Bermisheva M; Institute of Biochemistry and Genetics of the Ufa Federal Research Centre of the Russian Academy of Sciences, Ufa, Russia., Blok MJ; Maastricht University Medical Center, Department of Clinical Genetics, Maastricht, the Netherlands., Bogdanova NV; N.N. Alexandrov Research Institute of Oncology and Medical Radiology, Minsk, Belarus.; Hannover Medical School, Department of Radiation Oncology, Hannover, Germany.; Hannover Medical School, Gynaecology Research Unit, Hannover, Germany., Bonanni B; IEO, European Institute of Oncology IRCCS, Division of Cancer Prevention and Genetics, Milan, Italy., Burwinkel B; German Cancer Research Center (DKFZ), Molecular Epidemiology Group, C080, Heidelberg, Germany.; University of Heidelberg, Molecular Biology of Breast Cancer, University Womens Clinic Heidelberg, Heidelberg, Germany., Camp NJ; University of Utah, Department of Internal Medicine and Huntsman Cancer Institute, Salt Lake City, UT, USA., Campbell A; University of Edinburgh, Centre for Genomic and Experimental Medicine, Institute of Genetics & Cancer, Edinburgh, UK.; The University of Edinburgh, Usher Institute of Population Health Sciences and Informatics, Edinburgh, UK., Castelao JE; Instituto de Investigación Sanitaria Galicia Sur (IISGS), Xerencia de Xestion Integrada de Vigo-SERGAS, Oncology and Genetics Unit, Vigo, Spain., Cessna MH; Intermountain Healthcare, Salt Lake City, UT, USA., Chanock SJ; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA., Czene K; Karolinska Institutet, Department of Medical Epidemiology and Biostatistics, Stockholm, Sweden., Devilee P; Leiden University Medical Center, Department of Pathology, Leiden, the Netherlands.; Leiden University Medical Center, Department of Human Genetics, Leiden, the Netherlands., Dörk T; Hannover Medical School, Gynaecology Research Unit, Hannover, Germany., Engel C; University of Leipzig, Institute for Medical Informatics, Statistics and Epidemiology, Leipzig, Germany.; University of Leipzig, LIFE - Leipzig Research Centre for Civilization Diseases, Leipzig, Germany., Eriksson M; Karolinska Institutet, Department of Medical Epidemiology and Biostatistics, Stockholm, Sweden., Fasching PA; University Hospital Erlangen, Department of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen-EMN, Friedrich-Alexander University Erlangen-Nuremberg, Erlangen, Germany., Figueroa JD; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA.; The University of Edinburgh, Usher Institute of Population Health Sciences and Informatics, Edinburgh, UK.; The University of Edinburgh, Cancer Research UK Edinburgh Centre, Edinburgh, UK., Gabrielson M; Karolinska Institutet, Department of Medical Epidemiology and Biostatistics, Stockholm, Sweden., Gago-Dominguez M; Fundación Pública Galega de Medicina Xenómica, Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), Complejo Hospitalario Universitario de Santiago, SERGAS, Genomic Medicine Group, International Cancer Genetics and Epidemiology Group, Santiago de Compostela, Spain.; University of California San Diego, Moores Cancer Center, La Jolla, CA, USA., García-Closas M; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA., González-Neira A; Spanish National Cancer Research Centre (CNIO), Human Cancer Genetics Programme, Madrid, Spain., Grassmann F; Karolinska Institutet, Department of Medical Epidemiology and Biostatistics, Stockholm, Sweden.; Health and Medical University, Potsdam, Germany., Guénel P; INSERM, University Paris-Saclay, Center for Research in Epidemiology and Population Health (CESP), Team Exposome and Heredity, Villejuif, France., Gündert M; German Cancer Research Center (DKFZ), Molecular Epidemiology Group, C080, Heidelberg, Germany.; University of Heidelberg, Molecular Biology of Breast Cancer, University Womens Clinic Heidelberg, Heidelberg, Germany.; Helmholtz Zentrum München, German Research Center for Environmental Health, Institute of Diabetes Research, Neuherberg, Germany., Hadjisavvas A; The Cyprus Institute of Neurology & Genetics, Department of Cancer Genetics, Therapeutics and Ultrastructural Pathology, Nicosia, Cyprus., Hahnen E; Faculty of Medicine and University Hospital Cologne, University of Cologne, Center for Familial Breast and Ovarian Cancer, Cologne, Germany.; Faculty of Medicine and University Hospital Cologne, University of Cologne, Center for Integrated Oncology (CIO), Cologne, Germany., Hall P; Karolinska Institutet, Department of Medical Epidemiology and Biostatistics, Stockholm, Sweden.; Södersjukhuset, Department of Oncology, Stockholm, Sweden., Hamann U; German Cancer Research Center (DKFZ), Molecular Genetics of Breast Cancer, Heidelberg, Germany., Harrington PA; University of Cambridge, Centre for Cancer Genetic Epidemiology, Department of Oncology, Cambridge, UK., He W; Karolinska Institutet, Department of Medical Epidemiology and Biostatistics, Stockholm, Sweden., Hillemanns P; Hannover Medical School, Gynaecology Research Unit, Hannover, Germany., Hollestelle A; Erasmus MC Cancer Institute, Department of Medical Oncology, Rotterdam, the Netherlands., Hooning MJ; Erasmus MC Cancer Institute, Department of Medical Oncology, Rotterdam, the Netherlands., Hoppe R; Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Germany.; University of Tübingen, Tübingen, Germany., Howell A; University of Manchester, Division of Cancer Sciences, Manchester, UK., Humphreys K; Karolinska Institutet, Department of Medical Epidemiology and Biostatistics, Stockholm, Sweden., Jager A; Erasmus MC Cancer Institute, Department of Medical Oncology, Rotterdam, the Netherlands., Jakubowska A; Pomeranian Medical University, Department of Genetics and Pathology, International Hereditary Cancer Center, Szczecin, Poland.; Pomeranian Medical University, Independent Laboratory of Molecular Biology and Genetic Diagnostics, Szczecin, Poland., Khusnutdinova EK; Institute of Biochemistry and Genetics of the Ufa Federal Research Centre of the Russian Academy of Sciences, Ufa, Russia.; Bashkir State University, Department of Genetics and Fundamental Medicine, Ufa, Russia., Ko YD; Department of Internal Medicine, Johanniter GmbH Bonn, Johanniter Krankenhaus, Bonn, Germany., Kristensen VN; Department of Medical Genetics, Oslo University Hospital and University of Oslo, Oslo, Norway., Lindblom A; Karolinska Institutet, Department of Molecular Medicine and Surgery, Stockholm, Sweden.; Karolinska University Hospital, Department of Clinical Genetics, Stockholm, Sweden., Lissowska J; M. Sklodowska-Curie National Research Oncology Institute, Department of Cancer Epidemiology and Prevention, Warsaw, Poland., Lubiński J; Pomeranian Medical University, Department of Genetics and Pathology, International Hereditary Cancer Center, Szczecin, Poland., Mannermaa A; University of Eastern Finland, Translational Cancer Research Area, Kuopio, Finland.; University of Eastern Finland, Institute of Clinical Medicine, Pathology and Forensic Medicine, Kuopio, Finland.; Kuopio University Hospital, Biobank of Eastern Finland, Kuopio, Finland., Manoukian S; Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Unit of Medical Genetics, Department of Medical Oncology and Hematology, Milan, Italy., Margolin S; Södersjukhuset, Department of Oncology, Stockholm, Sweden.; Karolinska Institutet, Department of Clinical Science and Education, Södersjukhuset, Stockholm, Sweden., Mavroudis D; University Hospital of Heraklion, Department of Medical Oncology, Heraklion, Greece., Newman WG; University of Manchester, Manchester Academic Health Science Centre, Division of Evolution and Genomic Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester, UK.; St Mary's Hospital, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, North West Genomics Laboratory Hub, Manchester Centre for Genomic Medicine, Manchester, UK., Obi N; University Medical Center Hamburg-Eppendorf, Institute of Medical Biometry and Epidemiology, Hamburg, Germany., Panayiotidis MI; The Cyprus Institute of Neurology & Genetics, Department of Cancer Genetics, Therapeutics and Ultrastructural Pathology, Nicosia, Cyprus., Rashid MU; German Cancer Research Center (DKFZ), Molecular Genetics of Breast Cancer, Heidelberg, Germany.; Shaukat Khanum Memorial Cancer Hospital and Research Centre (SKMCH & RC), Department of Basic Sciences, Lahore, Pakistan., Rhenius V; University of Cambridge, Centre for Cancer Genetic Epidemiology, Department of Oncology, Cambridge, UK., Rookus MA; The Netherlands Cancer Institute - Antoni van Leeuwenhoek hospital, Division of Psychosocial Research and Epidemiology, Amsterdam, the Netherlands., Saloustros E; University Hospital of Larissa, Department of Oncology, Larissa, Greece., Sawyer EJ; King's College London, School of Cancer & Pharmaceutical Sciences, Comprehensive Cancer Centre, Guy's Campus, London, UK., Schmutzler RK; Faculty of Medicine and University Hospital Cologne, University of Cologne, Center for Familial Breast and Ovarian Cancer, Cologne, Germany.; Faculty of Medicine and University Hospital Cologne, University of Cologne, Center for Integrated Oncology (CIO), Cologne, Germany.; Faculty of Medicine and University Hospital Cologne, University of Cologne, Center for Molecular Medicine Cologne (CMMC), Cologne, Germany., Shah M; University of Cambridge, Centre for Cancer Genetic Epidemiology, Department of Oncology, Cambridge, UK., Sironen R; University of Eastern Finland, Translational Cancer Research Area, Kuopio, Finland.; University of Eastern Finland, Institute of Clinical Medicine, Pathology and Forensic Medicine, Kuopio, Finland.; Kuopio University Hospital, Imaging Center, Department of Clinical Pathology, Kuopio, Finland., Southey MC; Monash University, Precision Medicine, School of Clinical Sciences at Monash Health, Clayton, Victoria, Australia.; The University of Melbourne, Department of Clinical Pathology, Melbourne, Victoria, Australia.; Cancer Council Victoria, Cancer Epidemiology Division, Melbourne, Victoria, Australia., Suvanto M; University of Helsinki, Department of Obstetrics and Gynecology, Helsinki University Hospital, Helsinki, Finland., Tollenaar RAEM; Leiden University Medical Center, Department of Surgery, Leiden, the Netherlands., Tomlinson I; The University of Edinburgh, Cancer Research Centre, Edinburgh, UK., Truong T; INSERM, University Paris-Saclay, Center for Research in Epidemiology and Population Health (CESP), Team Exposome and Heredity, Villejuif, France., van der Kolk LE; The Netherlands Cancer Institute - Antoni van Leeuwenhoek hospital, Family Cancer Clinic, Amsterdam, the Netherlands., van Veen EM; University of Manchester, Manchester Academic Health Science Centre, Division of Evolution and Genomic Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester, UK.; St Mary's Hospital, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, North West Genomics Laboratory Hub, Manchester Centre for Genomic Medicine, Manchester, UK., Wappenschmidt B; Faculty of Medicine and University Hospital Cologne, University of Cologne, Center for Familial Breast and Ovarian Cancer, Cologne, Germany.; Faculty of Medicine and University Hospital Cologne, University of Cologne, Center for Integrated Oncology (CIO), Cologne, Germany., Yang XR; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA., Bolla MK; University of Cambridge, Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, Cambridge, UK., Dennis J; University of Cambridge, Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, Cambridge, UK., Dunning AM; University of Cambridge, Centre for Cancer Genetic Epidemiology, Department of Oncology, Cambridge, UK., Easton DF; University of Cambridge, Centre for Cancer Genetic Epidemiology, Department of Oncology, Cambridge, UK.; University of Cambridge, Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, Cambridge, UK., Lush M; University of Cambridge, Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, Cambridge, UK., Michailidou K; University of Cambridge, Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, Cambridge, UK.; The Cyprus Institute of Neurology & Genetics, Biostatistics Unit, Nicosia, Cyprus., Pharoah PDP; University of Cambridge, Centre for Cancer Genetic Epidemiology, Department of Oncology, Cambridge, UK.; University of Cambridge, Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, Cambridge, UK., Wang Q; University of Cambridge, Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, Cambridge, UK., Adank MA; The Netherlands Cancer Institute - Antoni van Leeuwenhoek hospital, Family Cancer Clinic, Amsterdam, the Netherlands., Schmidt MK; The Netherlands Cancer Institute - Antoni van Leeuwenhoek hospital, Division of Psychosocial Research and Epidemiology, Amsterdam, the Netherlands.; The Netherlands Cancer Institute, Division of Molecular Pathology, Amsterdam, the Netherlands., Andrulis IL; Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Fred A. Litwin Center for Cancer Genetics, Toronto, Ontario, Canada.; University of Toronto, Department of Molecular Genetics, Toronto, Ontario, Canada., Chang-Claude J; German Cancer Research Center (DKFZ), Division of Cancer Epidemiology, Heidelberg, Germany.; University Medical Center Hamburg-Eppendorf, Cancer Epidemiology Group, University Cancer Center Hamburg (UCCH), Hamburg, Germany., Nevanlinna H; University of Helsinki, Department of Obstetrics and Gynecology, Helsinki University Hospital, Helsinki, Finland., Chenevix-Trench G; QIMR Berghofer Medical Research Institute, Department of Genetics and Computational Biology, Brisbane, Queensland, Australia., Evans DG; University of Manchester, Manchester Academic Health Science Centre, Division of Evolution and Genomic Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester, UK.; St Mary's Hospital, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, North West Genomics Laboratory Hub, Manchester Centre for Genomic Medicine, Manchester, UK., Milne RL; Monash University, Precision Medicine, School of Clinical Sciences at Monash Health, Clayton, Victoria, Australia.; Cancer Council Victoria, Cancer Epidemiology Division, Melbourne, Victoria, Australia.; The University of Melbourne, Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, Melbourne, Victoria, Australia., Radice P; Fondazione IRCCS Istituto Nazionale dei Tumori (INT), Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Experimental Oncology, Milan, Italy., Peterlongo P; IFOM ETS - The AIRC Institute of Molecular Oncology, Genome Diagnostics Program, Milan, Italy. paolo.peterlongo@ifom.eu.

مؤلفون مشاركون: NBCS Collaborators, KConFab Investigators

المصدر: European journal of human genetics : EJHG [Eur J Hum Genet] 2023 May; Vol. 31 (5), pp. 578-587. Date of Electronic Publication: 2023 Jan 27.

نوع المنشور: Meta-Analysis; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 9302235 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5438 (Electronic) Linking ISSN: 10184813 NLM ISO Abbreviation: Eur J Hum Genet Subsets: MEDLINE

مواضيع طبية MeSH: Breast Neoplasms*/genetics , DNA Helicases*/genetics, Humans ; Female ; Triple Negative Breast Neoplasms/genetics ; Genetic Predisposition to Disease

المؤلفون: Lopes Cardozo JMN; Department of Surgery, The Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Amsterdam, the Netherlands.; European Organisation for Research and Treatment of Cancer Headquarters, Brussels, Belgium., Andrulis IL; Fred A. Litwin Center for Cancer Genetics, Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Ontario, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada., Bojesen SE; Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.; Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Dörk T; Gynaecology Research Unit, Hannover Medical School, Hannover, Germany., Eccles DM; Faculty of Medicine, University of Southampton, Southampton, United Kingdom., Fasching PA; Department of Gynecology and Obstetricss, Comprehensive Cancer Center Erlangen-EMN, Friedrich-Alexander University Erlangen-Nuremberg, University Hospital Erlangen, Erlangen, Germany., Hooning MJ; Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, the Netherlands., Keeman R; Division of Molecular Pathology, The Netherlands Cancer Institute, Amsterdam, the Netherlands., Nevanlinna H; Department of Obstetrics and Gynecology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland., Rutgers EJT; Department of Surgery, The Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Amsterdam, the Netherlands., Easton DF; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, United Kingdom.; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom., Hall P; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.; Department of Oncology, Södersjukhuset, Stockholm, Sweden., Pharoah PDP; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, United Kingdom.; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom., van 't Veer LJ; UCSF Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA., Schmidt MK; Division of Molecular Pathology, The Netherlands Cancer Institute, Amsterdam, the Netherlands.; Division of Psychosocial Research and Epidemiology, The Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Amsterdam, the Netherlands.; Department of Clinical Genetics, Leiden University Medical Center, Leiden, the Netherlands.

مؤلفون مشاركون: Breast Cancer Association Consortium and MINDACT Collaborators

المصدر: Journal of clinical oncology : official journal of the American Society of Clinical Oncology [J Clin Oncol] 2023 Apr 01; Vol. 41 (10), pp. 1849-1863. Date of Electronic Publication: 2023 Jan 23.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Intramural; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.

بيانات الدورية: Publisher: American Society of Clinical Oncology Country of Publication: United States NLM ID: 8309333 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1527-7755 (Electronic) Linking ISSN: 0732183X NLM ISO Abbreviation: J Clin Oncol Subsets: MEDLINE

مواضيع طبية MeSH: Breast Neoplasms*/pathology, Female ; Humans ; Risk Factors ; Prognosis ; Proportional Hazards Models ; Breast/pathology

المؤلفون: Morra A; The Netherlands Cancer Institute, Division of Molecular Pathology, Plesmanlaan 121, 1066 Amsterdam, the Netherlands. Electronic address: a.morra@nki.nl., Mavaddat N; University of Cambridge, Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, Cambridge, UK., Muranen TA; University of Helsinki, Department of Obstetrics and Gynecology, Helsinki University Hospital, Helsinki, Finland., Ahearn TU; National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Division of Cancer Epidemiology and Genetics, Bethesda, MD, USA., Allen J; University of Cambridge, Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, Cambridge, UK., Andrulis IL; Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Fred A. Litwin Center for Cancer Genetics, Toronto, ON, Canada; University of Toronto, Department of Molecular Genetics, Toronto, ON, Canada., Auvinen P; University of Eastern Finland, Translational Cancer Research Area, Kuopio, Finland; University of Eastern Finland, Institute of Clinical Medicine, Oncology, Kuopio, Finland; Kuopio University Hospital, Department of Oncology, Cancer Center, Kuopio, Finland., Becher H; University Medical Center Hamburg-Eppendorf, Institute of Medical Biometry and Epidemiology, Hamburg, Germany., Behrens S; German Cancer Research Center, Division of Cancer Epidemiology, Heidelberg, Germany., Blomqvist C; University of Helsinki, Department of Oncology, Helsinki University Hospital, Helsinki, Finland., Bojesen SE; Copenhagen University Hospital, Copenhagen General Population Study, Herlev and Gentofte Hospital, Herlev, Denmark; Copenhagen University Hospital, Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Herlev, Denmark; University of Copenhagen, Faculty of Health and Medical Sciences, Copenhagen, Denmark., Bolla MK; University of Cambridge, Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, Cambridge, UK., Brauch H; Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Germany; University of Tübingen, iFIT-Cluster of Excellence, Tübingen, Germany; German Cancer Consortium and German Cancer Research Center, Partner Site Tübingen, Tübingen, Germany., Camp NJ; University of Utah, Department of Internal Medicine and Huntsman Cancer Institute, Salt Lake City, UT, USA., Carvalho S; University of Cambridge, Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, Cambridge, UK., Castelao JE; Instituto de Investigación Sanitaria Galicia Sur, Xerencia de Xestion Integrada de Vigo-SERGAS, Oncology and Genetics Unit, Vigo, Spain., Cessna MH; Intermountain Healthcare, Salt Lake City, UT, USA., Chang-Claude J; German Cancer Research Center, Division of Cancer Epidemiology, Heidelberg, Germany; University Medical Center Hamburg-Eppendorf, Cancer Epidemiology Group, University Cancer Center Hamburg, Hamburg, Germany., Chenevix-Trench G; QIMR Berghofer Medical Research Institute, Department of Genetics and Computational Biology, Brisbane, QLD, Australia., Czene K; Karolinska Institutet, Department of Medical Epidemiology and Biostatistics, Stockholm, Sweden., Decker B; University of Cambridge, Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, Cambridge, UK; Foundation Medicine, Inc, Pathology, Cambridge, MA, USA., Dennis J; University of Cambridge, Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, Cambridge, UK., Dörk T; Hannover Medical School, Gynaecology Research Unit, Hannover, Germany., Dorling L; University of Cambridge, Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, Cambridge, UK., Dunning AM; University of Cambridge, Centre for Cancer Genetic Epidemiology, Department of Oncology, Cambridge, UK., Ekici AB; Comprehensive Cancer Center Erlangen-EMN, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Institute of Human Genetics, Erlangen, Germany., Eriksson M; Karolinska Institutet, Department of Medical Epidemiology and Biostatistics, Stockholm, Sweden., Evans DG; University of Manchester, Manchester Academic Health Science Centre, Division of Evolution and Genomic Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester, UK; St Mary's Hospital, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, North West Genomics Laboratory Hub, Manchester Centre for Genomic Medicine, Manchester, UK., Fasching PA; University Hospital Erlangen, Department of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen-EMN, Friedrich-Alexander University Erlangen-Nuremberg, Erlangen, Germany., Figueroa JD; National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Division of Cancer Epidemiology and Genetics, Bethesda, MD, USA; The University of Edinburgh, Usher Institute of Population Health Sciences and Informatics, Edinburgh, UK; The University of Edinburgh, Cancer Research UK Edinburgh Centre, Edinburgh, UK., Flyger H; Copenhagen University Hospital, Department of Breast Surgery, Herlev and Gentofte Hospital, Herlev, Denmark., Gago-Dominguez M; Fundación Pública Galega de Medicina Xenómica, Instituto de Investigación Sanitaria de Santiago de Compostela, Complejo Hospitalario Universitario de Santiago, SERGAS, Genomic Medicine Group, International Cancer Genetics and Epidemiology Group, Santiago de Compostela, Spain; University of California San Diego, Moores Cancer Center, La Jolla, CA, USA., García-Closas M; National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Division of Cancer Epidemiology and Genetics, Bethesda, MD, USA., Geurts-Giele WRR; Erasmus University Medical Center, Department of Clinical Genetics, Rotterdam, the Netherlands., Giles GG; Cancer Council Victoria, Cancer Epidemiology Division, Melbourne, VIC, Australia; The University of Melbourne, Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, Melbourne, VIC, Australia; Monash University, Precision Medicine, School of Clinical Sciences at Monash Health, Clayton, VIC, Australia., Guénel P; INSERM, University Paris-Saclay, Center for Research in Epidemiology and Population Health, Team Exposome and Heredity, Villejuif, France., Gündert M; German Cancer Research Center, Molecular Epidemiology Group, C080, Heidelberg, Germany; University of Heidelberg, Molecular Biology of Breast Cancer, University Womens Clinic Heidelberg, Heidelberg, Germany; Helmholtz Zentrum München, German Research Center for Environmental Health, Institute of Diabetes Research, Neuherberg, Germany., Hahnen E; Faculty of Medicine and University Hospital Cologne, University of Cologne, Center for Familial Breast and Ovarian Cancer, Cologne, Germany; Faculty of Medicine and University Hospital Cologne, University of Cologne, Center for Integrated Oncology, Cologne, Germany., Hall P; Karolinska Institutet, Department of Medical Epidemiology and Biostatistics, Stockholm, Sweden; Södersjukhuset, Department of Oncology, Stockholm, Sweden., Hamann U; German Cancer Research Center, Molecular Genetics of Breast Cancer, Heidelberg, Germany., Harrington PA; University of Cambridge, Centre for Cancer Genetic Epidemiology, Department of Oncology, Cambridge, UK., He W; Karolinska Institutet, Department of Medical Epidemiology and Biostatistics, Stockholm, Sweden., Heikkilä P; University of Helsinki, Department of Pathology, Helsinki University Hospital, Helsinki, Finland., Hooning MJ; Erasmus MC Cancer Institute, Department of Medical Oncology, Rotterdam, the Netherlands., Hoppe R; Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Germany; University of Tübingen, Tübingen, Germany., Howell A; University of Manchester, Division of Cancer Sciences, Manchester, UK., Humphreys K; Karolinska Institutet, Department of Medical Epidemiology and Biostatistics, Stockholm, Sweden., Jakubowska A; Pomeranian Medical University, Department of Genetics and Pathology, International Hereditary Cancer Center, Szczecin, Poland; Pomeranian Medical University, Independent Laboratory of Molecular Biology and Genetic Diagnostics, Szczecin, Poland., Jung AY; German Cancer Research Center, Division of Cancer Epidemiology, Heidelberg, Germany., Keeman R; The Netherlands Cancer Institute, Division of Molecular Pathology, Plesmanlaan 121, 1066 Amsterdam, the Netherlands., Kristensen VN; University of Oslo, Institute of Clinical Medicine, Faculty of Medicine, Oslo, Norway; Oslo University Hospital and University of Oslo, Department of Medical Genetics, Oslo, Norway., Lubiński J; Pomeranian Medical University, Department of Genetics and Pathology, International Hereditary Cancer Center, Szczecin, Poland., Mannermaa A; University of Eastern Finland, Translational Cancer Research Area, Kuopio, Finland; University of Eastern Finland, Institute of Clinical Medicine, Pathology and Forensic Medicine, Kuopio, Finland; Kuopio University Hospital, Biobank of Eastern Finland, Kuopio, Finland., Manoochehri M; German Cancer Research Center, Molecular Genetics of Breast Cancer, Heidelberg, Germany., Manoukian S; Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Unit of Medical Genetics, Department of Medical Oncology and Hematology, Milan, Italy., Margolin S; Södersjukhuset, Department of Oncology, Stockholm, Sweden; Karolinska Institutet, Department of Clinical Science and Education, Södersjukhuset, Stockholm, Sweden., Mavroudis D; University Hospital of Heraklion, Department of Medical Oncology, Heraklion, Greece., Milne RL; Cancer Council Victoria, Cancer Epidemiology Division, Melbourne, VIC, Australia; The University of Melbourne, Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, Melbourne, VIC, Australia; Monash University, Precision Medicine, School of Clinical Sciences at Monash Health, Clayton, VIC, Australia., Mulligan AM; University of Toronto, Department of Laboratory Medicine and Pathobiology, Toronto, ON, Canada; University Health Network, Laboratory Medicine Program, Toronto, ON, Canada., Newman WG; University of Manchester, Manchester Academic Health Science Centre, Division of Evolution and Genomic Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester, UK; St Mary's Hospital, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, North West Genomics Laboratory Hub, Manchester Centre for Genomic Medicine, Manchester, UK., Park-Simon TW; Hannover Medical School, Gynaecology Research Unit, Hannover, Germany., Peterlongo P; IFOM ETS - the AIRC Institute of Molecular Oncology, Genome Diagnostics Program, Milan, Italy., Pharoah PDP; University of Cambridge, Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, Cambridge, UK; University of Cambridge, Centre for Cancer Genetic Epidemiology, Department of Oncology, Cambridge, UK., Rhenius V; University of Cambridge, Centre for Cancer Genetic Epidemiology, Department of Oncology, Cambridge, UK., Saloustros E; University Hospital of Larissa, Department of Oncology, Larissa, Greece., Sawyer EJ; King's College London, School of Cancer & Pharmaceutical Sciences, Comprehensive Cancer Centre, Guy's Campus, London, UK., Schmutzler RK; Faculty of Medicine and University Hospital Cologne, University of Cologne, Center for Familial Breast and Ovarian Cancer, Cologne, Germany; Faculty of Medicine and University Hospital Cologne, University of Cologne, Center for Integrated Oncology, Cologne, Germany; Faculty of Medicine and University Hospital Cologne, University of Cologne, Center for Molecular Medicine Cologne, Cologne, Germany., Shah M; University of Cambridge, Centre for Cancer Genetic Epidemiology, Department of Oncology, Cambridge, UK., Spurdle AB; QIMR Berghofer Medical Research Institute, Population Health Program, Brisbane, QLD, Australia., Tomlinson I; University of Birmingham, Institute of Cancer and Genomic Sciences, Birmingham, UK; University of Oxford, Wellcome Trust Centre for Human Genetics and Oxford NIHR Biomedical Research Centre, Oxford, UK., Truong T; INSERM, University Paris-Saclay, Center for Research in Epidemiology and Population Health, Team Exposome and Heredity, Villejuif, France., van Veen EM; University of Manchester, Manchester Academic Health Science Centre, Division of Evolution and Genomic Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester, UK; St Mary's Hospital, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, North West Genomics Laboratory Hub, Manchester Centre for Genomic Medicine, Manchester, UK., Vreeswijk MPG; Leiden University Medical Center, Department of Human Genetics, Leiden, the Netherlands., Wang Q; University of Cambridge, Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, Cambridge, UK., Wendt C; Södersjukhuset, Department of Oncology, Stockholm, Sweden; Karolinska Institutet, Department of Clinical Science and Education, Södersjukhuset, Stockholm, Sweden., Yang XR; National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Division of Cancer Epidemiology and Genetics, Bethesda, MD, USA., Nevanlinna H; University of Helsinki, Department of Obstetrics and Gynecology, Helsinki University Hospital, Helsinki, Finland., Devilee P; Leiden University Medical Center, Department of Human Genetics, Leiden, the Netherlands; Leiden University Medical Center, Department of Pathology, Leiden, the Netherlands., Easton DF; University of Cambridge, Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, Cambridge, UK; University of Cambridge, Centre for Cancer Genetic Epidemiology, Department of Oncology, Cambridge, UK., Schmidt MK; The Netherlands Cancer Institute, Division of Molecular Pathology, Plesmanlaan 121, 1066 Amsterdam, the Netherlands; The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Division of Psychosocial Research and Epidemiology, Amsterdam, the Netherlands. Electronic address: mk.schmidt@nki.nl.

مؤلفون مشاركون: NBCS Collaborators; Oslo University Hospital-Radiumhospitalet, Department of Cancer Genetics, Institute for Cancer Research, Oslo, Norway; University of Oslo, Institute of Clinical Medicine, Faculty of Medicine, Oslo, Norway; Vestre Viken Hospital, Department of Research, Drammen, Norway; Oslo University Hospital, Department of Tumor Biology, Institute for Cancer Research, Oslo, Norway; Oslo University Hospital-Radiumhospitalet, Department of Oncology, Division of Surgery, Cancer and Transplantation Medicine, Oslo, Norway; Akershus University Hospital, Department of Oncology, Lørenskog, Norway; Oslo University Hospital, Oslo Breast Cancer Research Consortium, Oslo, Norway; Oslo University Hospital and University of Oslo, Department of Medical Genetics, Oslo, Norway; The Arctic University of Norway, Department of Community Medicine, Tromsø, Norway; The Arctic University of Norway, Core Facility for Biobanking, Tromsø, Norway., kConFab Investigators; Peter MacCallum Cancer Center, Research Department, Melbourne, VIC, Australia; The University of Melbourne, Sir Peter MacCallum Department of Oncology, Melbourne, VIC, Australia.

المصدر: American journal of human genetics [Am J Hum Genet] 2023 Mar 02; Vol. 110 (3), pp. 475-486. Date of Electronic Publication: 2023 Feb 23.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 0370475 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1537-6605 (Electronic) Linking ISSN: 00029297 NLM ISO Abbreviation: Am J Hum Genet Subsets: MEDLINE

مواضيع طبية MeSH: Breast Neoplasms*/genetics, Female ; Humans ; Genes, BRCA2 ; Germ-Line Mutation ; Germ Cells ; Genetic Predisposition to Disease