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المؤلفون: Darin Pauley, Pim Cuijpers, Clara Miguel, Eirini Karyotaki, Davide Papola
المساهمون: Clinical Psychology, APH - Global Health, APH - Mental Health, World Health Organization (WHO) Collaborating Center, APH - Methodology
المصدر: Pauley, D, Cuijpers, P, Papola, D, Miguel, C & Karyotaki, E 2023, ' Two decades of digital interventions for anxiety disorders : A systematic review and meta-analysis of treatment effectiveness ', Psychological Medicine, vol. 53, no. 2, pp. 567-579 . https://doi.org/10.1017/S0033291721001999
Psychological Medicine, 53(2), 567-579. Cambridge University Pressمصطلحات موضوعية: Generalized anxiety disorder, business.industry, Panic disorder, effect size, Social anxiety, Psychological intervention, effectiveness, digital interventions, medicine.disease, meta-analysis, Psychiatry and Mental health, SDG 3 - Good Health and Well-being, Meta-analysis, medicine, Anxiety, medicine.symptom, business, Applied Psychology, Anxiety disorder, Agoraphobia, Clinical psychology, Anxiety disorders
الوصف: Background Digital interventions for anxiety disorders are a promising solution to address barriers to evidence-based treatment access. Precise and powerful estimates of digital intervention effectiveness for anxiety disorders are necessary for further adoption in practice. The present systematic review and meta-analysis examined the effectiveness of digital interventions across all anxiety disorders and specific to each disorder v. wait-list and care-as-usual controls. Methods A systematic search of bibliographic databases identified 15 030 abstracts from inception to 1 January 2020. Forty-seven randomized controlled trials (53 comparisons; 4958 participants) contributed to the meta-analysis. Subgroup analyses were conducted by an anxiety disorder, risk of bias, treatment support, recruitment, location and treatment adherence. Results A large, pooled effect size of g = 0.80 [95% Confidence Interval: 0.68–0.93] was found in favor of digital interventions. Moderate to large pooled effect sizes favoring digital interventions were found for generalized anxiety disorder (g = 0.62), mixed anxiety samples (g = 0.68), panic disorder with or without agoraphobia (g = 1.08) and social anxiety disorder (g = 0.76) subgroups. No subgroups were significantly different or related to the pooled effect size. Notably, the effects of guided interventions (g = 0.84) and unguided interventions (g = 0.64) were not significantly different. Supplemental analysis comparing digital and face-to-face interventions (9 comparisons; 683 participants) found no significant difference in effect [g = 0.14 favoring digital interventions; Confidence Interval: −0.01 to 0.30]. Conclusion The precise and powerful estimates found further justify the application of digital interventions for anxiety disorders in place of wait-list or usual care.
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المؤلفون: N. Lazar, Houda Salhi, I. El Harch, S. Benmaamar, N. Otmani, M. Maiouak, H. El Ouahabi, Nabil Tachfouti, S. El Fakir, Noura Qarmiche
المصدر: L'Encéphale. 48:601-606
مصطلحات موضوعية: Male, Adult, medicine.medical_specialty, Multivariate analysis, Disease, Anxiety, Hospital Anxiety and Depression Scale, Logistic regression, Arts and Humanities (miscellaneous), Internal medicine, Diabetes mellitus, Prevalence, Humans, Medicine, Depression (differential diagnoses), Depression, business.industry, Confounding, Middle Aged, medicine.disease, Anxiety Disorders, Psychiatry and Mental health, Cross-Sectional Studies, Diabetes Mellitus, Type 2, Female, medicine.symptom, business
الوصف: Aims To estimate prevalence of anxiety and depression in patients with diabetes mellitus and identify their determinants. Methods A cross-sectional study was conducted at Hassan II University-Hospital of Fes in 2019–2020. Anxiety and depression were measured by using the Hospital Anxiety and Depression Scale (HADS). Multivariate analysis by logistic regression was used to determine factors associated with depression and anxiety, adjusting for confounding factors. All statistical analyses were conducted using EPIINFO7. Results A total of 243 diabetics were included in the study. The average age of the participants was 48.07 ± 14.25 years, 58% were females and 72% were diagnosed with diabetes type II. The prevalence of depressive symptoms and anxiety symptoms was (18, 1%, CI95% = (13–23)) and (29.6%, CI95% = (24–35)), respectively. The prevalence of depression and anxiety was higher among women than man and increases with increasing duration of the disease. In multivariate analysis, illiterates (OR = 3.19, CI95% = (1.46–6.98)), those with depression (OR = 3.61, CI95% = (1.78–7.32)), and type 1 diabetics (OR = 3.22, CI95% = (1.44–7.21)) are a higher risk of developing anxiety. Depression was associated with older age (OR = 2, 65, CI95% = (1, 14–6, 14)), use of insulin (OR = 3.77 CI95% = (1.50–9.44)) and anxiety symptoms (OR = 4, 27, CI95% = (2, 05–8, 91)). Conclusion High prevalence of depressive and anxiety symptoms in diabetics suggests consideration of psychological aspect in implementation of diabetes managing program.
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المؤلفون: Karel Kostev, Jens Bohlken, Wolfgang Hoffmann, Steffie Riedel-Heller, Bernhard Michalowsky
المصدر: Journal of Psychiatric Research
Journal of psychiatric research 143, 43-49 (2021). doi:10.1016/j.jpsychires.2021.08.016مصطلحات موضوعية: Healthcare utilization, medicine.medical_specialty, Cross-sectional study, Population, Adjustment disorders, Anxiety, Article, epidemiology [Depressive Disorder], Elderly, Lockdown, Pandemic, Humans, Medicine, ddc:610, education, Psychiatry, Pandemics, Biological Psychiatry, Depression (differential diagnoses), Aged, epidemiology [Depression], Depressive Disorder, education.field_of_study, Primary Health Care, Descriptive statistics, Depression, SARS-CoV-2, business.industry, COVID-19, epidemiology [Anxiety], medicine.disease, Anxiety Disorders, Mental health, Recognition, Psychiatry and Mental health, Cross-Sectional Studies, epidemiology [Anxiety Disorders], Communicable Disease Control, Female, medicine.symptom, business
الوصف: Several studies revealed that mental disorders' prevalence increased during the COVID-19 pandemic, particularly in young and female individuals. Such studies represent individuals' subjective perceptions and not the number of mental health cases treated in primary care. Thus, this study aimed to describe the changes in depression, anxiety, and stress disorder diagnoses in General Practitioner (GP) practices during the COVID-19 pandemic. More than three million patients of 757 German GP practices were included in this cross-sectional analysis. Descriptive statistics were used to assess changes in the number of incident depression, anxiety disorders, and reaction to severe stress and adjustment disorders documented by GPs in 2020 compared to the average of the years 2017-2019. There was a tremendous decrease in mental health diagnoses during the first lockdown that was only slightly compensated later. Overall populations and the entire year 2020, there was no change in documented depression (0%) and stress disorders (1%), but anxiety disorders were more often documented (+19%), especially for the elderly population (>80 years; +24%). This population group also received more frequently new depression (+12%) and stress disorder diagnoses (23%). The younger population was diagnosed more frequently at the end of 2020, nine months after the first lockdown. Anxiety disorders but not depression and stress diagnoses were elevated, which is not in line with previously published studies. We speculate that the elderly population was affected most by the pandemic immediately after the first lockdown was announced. The younger population has probably become more and more affected the longer the pandemic lasts.
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المؤلفون: Chih-Min Liu, Yi-Ting Lin, Yi-Ling Chien, Chen-Chung Liu, Ming H. Hsieh, Tzung-Jeng Hwang, Hai-Gwo Hwu
المصدر: Journal of the Formosan Medical Association. 121:1159-1166
مصطلحات موضوعية: Psychosis, medicine.medical_specialty, Bipolar Disorder, business.industry, Medical record, At risk mental state, General Medicine, medicine.disease, Anxiety Disorders, Mental health, Psychotic Disorders, Cohort, medicine, Humans, Anxiety, Big Five personality traits, medicine.symptom, business, Psychiatry, Follow-Up Studies, Retrospective Studies, Cohort study
الوصف: Background Follow-up of subjects with putative pre-psychotic states is essential to clarify the transition process to psychosis, while "non-converters" also deserve clinical attention as many may evolve into other psychiatric disorders with diverse outcomes. This study aimed to examine help-seeking individuals who have been labelled at clinical high-risk state but not converting to full-blown psychosis during first two years of follow-up. Methods A retrospective observational cohort study of help-seeking subjects was conducted by reviewing medical records of participants in a previous early psychosis study at the study hospital between 2006 and 2020. We portrayed those who developed first episode psychosis after first 2-year follow-up in detail, and provided sketches of clinical macrophenotypes other than psychosis emerging from subjects among different risk groups. Results Among 132 eligible subjects, data of 98 (74.2%) were available for detailed evaluation. Of these, 15 transitioned to first-episode psychosis (11.4%) with time to psychosis from 2 to 11 years, 11 had anxiety spectrum (8.3%), 11 had depressive spectrum (8.3%), 10 had obsessive compulsive (7.6%), 5 had bipolar spectrum disorders (3.8%), 13 had predominantly schizotypal (9.8%) and 4 had other personality traits (3%), and 13 had problems attributable to adjustment or developmental issues (9.8%). Conclusions Various diagnoses, either full- or sub-threshold, appropriately describe the diverse clinical phenomenology of a cohort presenting with non-specific and/or subthreshold psychotic symptoms. The clinical high-at-risk mental state (CHARMS) paradigm provides a reasonable transdiagnostic approach for orienting clinicians' attention toward young subjects seeking mental health help at an early stage of illness to potentially pluripotent trajectories.
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المؤلفون: Melonie Vaughn, Victoria B. Risbrough, Samantha Friend
المصدر: Biological Psychiatry. 91:438-448
مصطلحات موضوعية: Inflammation, Oncology, medicine.medical_specialty, Traumatic brain injury, business.industry, medicine.medical_treatment, medicine.disease, Anxiety Disorders, nervous system diseases, Stress Disorders, Post-Traumatic, Cytokine, Internal medicine, Brain Injuries, Traumatic, Concussion, Epidemiology, medicine, Humans, Anxiety, Biomarker (medicine), medicine.symptom, business, Brain Concussion, Biological Psychiatry, Depression (differential diagnoses)
الوصف: In the past decade, there has been an increasing awareness that traumatic brain injury (TBI) and concussion substantially increase the risk for developing psychiatric disorders. Even mild TBI increases the risk for depression and anxiety disorders such as posttraumatic stress disorder by two- to threefold, predisposing patients to further functional impairment. This strong epidemiological link supports examination of potential mechanisms driving neuropsychiatric symptom development after TBI. One potential mechanism for increased neuropsychiatric symptoms after TBI is via inflammatory processes, as central nervous system inflammation can last years after initial injury. There is emerging preliminary evidence that TBI patients with posttraumatic stress disorder or depression exhibit increased central and peripheral inflammatory markers compared with TBI patients without these comorbidities. Growing evidence has demonstrated that immune signaling in animals plays an integral role in depressive- and anxiety-like behaviors after severe stress or brain injury. In this review, we will 1) discuss current evidence for chronic inflammation after TBI in the development of neuropsychiatric symptoms, 2) highlight potential microglial activation and cytokine signaling contributions, and 3) discuss potential promise and pitfalls for immune-targeted interventions and biomarker strategies to identify and treat TBI patients with immune-related neuropsychiatric symptoms.
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6Depression, Anxiety, and Correlating Factors in Endometriosis: A Systematic Review and Meta-Analysis
المؤلفون: Marlies Y. Bongers, Mikal van Poll, Nehalennia van Hanegem, Carsten Leue, Esther van Barneveld, Arianne Lim, Frits H.M. van Osch, Jessica Manders, Linda Visser
المصدر: Journal of Women's Health. 31:219-230
مصطلحات موضوعية: medicine.medical_specialty, SYMPTOMS, IMPACT, Endometriosis, Anxiety, 03 medical and health sciences, EXPERIENCE SAMPLING METHOD, 0302 clinical medicine, QUALITY-OF-LIFE, Internal medicine, medicine, Humans, pain, PSYCHIATRIC DISTURBANCES, 030212 general & internal medicine, CHRONIC PELVIC PAIN, Depression (differential diagnoses), PSYCHOLOGICAL-ASPECTS, 030219 obstetrics & reproductive medicine, Depression, business.industry, Pelvic pain, Chronic pain, INFERTILE WOMEN, General Medicine, medicine.disease, Anxiety Disorders, Comorbidity, BECK DEPRESSION, Meta-analysis, Quality of Life, Female, medicine.symptom, Sexual function, business, psychosomatic symptoms, MENTAL-HEALTH
الوصف: Background: Endometriosis stage is not directly related to the burden of symptoms, and recurrence of symptoms occurs frequently. It is suggested that symptoms are associated with psychological distress, as in depression and anxiety disorders. Our aim was to explore the strength of the associations between endometriosis and depression or anxiety and to review correlating factors. Materials and Methods: A literature search was carried out using the electronic databases Embase, PubMed, Web-of-science, and PsycINFO. Search terms related to depression, anxiety, and endometriosis were combined resulting in 1,837 records. Articles were included when describing an association between patients with endometriosis and symptoms of depression or anxiety assessed by validated tools, structured psychiatric interviews, or a documented diagnosis. With 47 articles a systematic qualitative review was performed. Seventeen studies were eligible for meta-analysis. Results: Endometriosis patients experienced significantly more symptoms of depression (standardized mean difference [SMD] of 0.71 (95% confidence interval [CI] 0.36-1.06)) and anxiety (SMD 0.60 (95% CI 0.35-0.84)) compared with healthy controls, but no differences were found comparing endometriosis patients with other chronic pelvic pain patients (SMD -0.01 [95% CI -0.17 to 0.15] for depression and SMD -0.02 [95% CI -0.22 to 0.18] for anxiety). Besides the effect of pain, other correlating factors included age, quality of life, quality of sleep, fatigue, sexual function, gastrointestinal symptoms, comorbidity, self-esteem, emotional self-efficacy, coping style, social adjustment, pain imagery, and pain sensitization. Conclusion: This systematic review supports the assumption that symptoms of depression and anxiety occur frequently in endometriosis patients and are related to chronic pain. Correlating factors should further be investigated.
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69dc4a1acba8a9f58ca77f0bd2f11e28
https://doi.org/10.1089/jwh.2021.0021 -
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المؤلفون: Cillian P. McDowell, Matthew P. Herring, Mark Lyons, Brett R. Gordon
المصدر: Journal of Affective Disorders. 299:102-107
مصطلحات موضوعية: Male, medicine.medical_specialty, Strength training, medicine.drug_class, Rest, media_common.quotation_subject, Anxiety, Anxiolytic, law.invention, Young Adult, Randomized controlled trial, law, medicine, Humans, Young adult, Adverse effect, Exercise, media_common, business.industry, Resistance Training, medicine.disease, Anxiety Disorders, Psychiatry and Mental health, Clinical Psychology, Physical therapy, Female, medicine.symptom, Worry, business, Anxiety disorder
الوصف: Background: The effects of a single bout of resistance exercise (RE) on state anxiety and worry symptoms are understudied. Further, how resistance exercise training (RET) changes response to acute RE is unknown. Methods: Sixty-two untrained young adults (mean age (y):26.6; RET n=27, Wait-list (WL): n=35, 62.9% female) were randomized to an eight-week, ecologically-valid, guidelines-based RET condition, or eight-week WL control condition. Two acute RE trials were nested within the design at week one and eight, to determine RE response, and change in RE response following RET. The RET condition completed a twice-weekly RET intervention. The WL condition completed 30-minute bouts of quiet-rest at week one and eight. Two-condition (RE/quiet-rest) x two-time (pre/post) x two-session (weeks one/eight) RM-ANCOVAs examined differences between acute RE and quiet-rest pre-post and between acute sessions. Sub-analyses were conducted among young adults with analogue-Generalized Anxiety Disorder (AGAD). Primary outcomes were anxiety and worry symptoms. Results: Compliance was 99% (Rate of perceived exertion (6-20)=14±1, Muscle soreness (1-10)=4±2), with no adverse events. There were no significant three-way interactions for anxiety symptoms or worry symptoms (all p≥0.51) among the total sample or AGAD sample. The magnitude of change in outcomes at each session for both samples were small and non-significant (Hedges’ d=-0.26 to 0.23). Limitations: Post-condition assessment of primary outcomes was only conducted at a single time point. Conclusion: RE did not elicit significant reductions in state anxiety or worry symptoms ten minutes post-RE. RET did not change response to acute RE. Clinicians should encourage RET for maximum anxiolytic benefits.
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المؤلفون: Jae E. Park, Sonya B. Norman, Peter J. Colvonen, Moira Haller, Guadalupe L. Rivera, Laura D. Straus, Sonia Ancoli-Israel
المصدر: Psychol Trauma
Psychological trauma : theory, research, practice and policy, vol 14, iss 2مصطلحات موضوعية: Pediatrics, medicine.medical_specialty, Sleep Apnea, Social Psychology, Substance-Related Disorders, PsycINFO, veteran, behavioral disciplines and activities, Article, OSA, Stress Disorders, Post-Traumatic, stomatognathic system, Clinical Research, CPAP, Behavioral and Social Science, mental disorders, Positive airway pressure, Psychology, Humans, Medicine, Lung, SUD, Residential Treatment, Stress Disorders, Veterans, Sleep Apnea, Obstructive, Obstructive, business.industry, Sleep apnea, PTSD, Post-Traumatic Stress Disorder (PTSD), medicine.disease, Anxiety Disorders, Brain Disorders, nervous system diseases, respiratory tract diseases, Obstructive sleep apnea, Substance abuse, Clinical Psychology, Posttraumatic stress, Mental Health, Good Health and Well Being, Post-Traumatic, Sleep diary, Substance use, Sleep Research, business
الوصف: BACKGROUND Obstructive sleep apnea (OSA) is often comorbid with both substance use disorders (SUD) and posttraumatic stress disorder (PTSD), yet frequently goes undiagnosed and untreated. We present data on the feasibility and acceptability of objective OSA diagnosis procedures, findings on OSA prevalence, and the relationship between OSA and baseline SUD/PTSD symptoms among veterans in residential treatment for comorbid PTSD/SUD. METHODS Participants were 47 veterans admitted to residential PTSD/SUD treatment. Participants completed questionnaires assessing PTSD and sleep symptoms, and filled out a sleep diary for seven days. Apnea-hypopnea index (AHI) was recorded using the overnight Home Sleep Apnea test (HSAT; OSA was diagnosed with AHI ≥ 5). RESULTS Objective OSA diagnostic testing was successfully completed in 95.7% of participants. Of the 45 veterans who went through HSAT, 46.7% had no OSA, 35.6% received a new OSA diagnosis, and 8.9% were previously diagnosed with OSA and were using positive airway pressure treatment (PAP); an additional 8.9% were previously diagnosed with OSA, reconfirmed with the HSAT, but were not using PAP. One hundred percent of respondents during follow-up deemed the testing protocol's usefulness as "Good" or "Excellent." CONCLUSION OSA diagnostic testing on the residential unit was feasible and acceptable by participants and was effective in diagnosing OSA. OSA testing should be considered for everyone entering a SUD and PTSD residential unit. (PsycInfo Database Record (c) 2021 APA, all rights reserved).
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eaf041fb9fd973dbf66aa0563eb7dd6
https://doi.org/10.1037/tra0001066 -
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المؤلفون: Petr Bielicki, Soňa Nevšímalová, Karel Sonka, Iva Příhodová, Jelena Skibova, Simona Dostálová
المصدر: Pediatric Neurology. 127:28-31
مصطلحات موضوعية: Adult, Male, Sleep Wake Disorders, Pediatrics, medicine.medical_specialty, Adolescent, Polysomnography, Comorbidity, Cohort Studies, Young Adult, Developmental Neuroscience, mental disorders, Specific Learning Disorder, medicine, Humans, Attention deficit hyperactivity disorder, International Classification of Sleep Disorders, Child, Depressive Disorder, medicine.diagnostic_test, business.industry, Mental Disorders, Actigraphy, medicine.disease, Anxiety Disorders, Neurology, Attention Deficit Disorder with Hyperactivity, Pediatrics, Perinatology and Child Health, Anxiety, Female, Sleep diary, Sleep Stages, Neurology (clinical), medicine.symptom, Sleep onset, business
الوصف: Background/Objective Delayed sleep-wake phase disorder (DSWPD) is a chronic condition with a multifactorial etiology that primarily affects adolescents, significantly influencing their quality of life. In clinical practice, the contribution of intrinsic and behavioral factors is difficult to determine. The aim of our study was to compare data from clinical interviews, sleep diaries, actigraphy and nocturnal polysomnography (PSG) in a cohort of adolescents with DSWPD, and to assess psychiatric/neurodevelopmental comorbidity. Patients and methods Thirty-one patients (22 male; mean age 15.4±2.2 years, range 12−19 years) with a diagnosis of DSWPD based on detailed history, sleep diary and actigraphy underwent nocturnal polysomnography (PSG), neurological, psychological and psychiatric examination. Results Attention deficit hyperactivity disorder (ADHD) was present in 14 cases (45%), specific learning difficulties in 9 (29%), and mood disorder (anxiety/depression) in 16 patients (52%). PSG revealed sleep-onset delay in only 12 (38%) cases. No differences in clinical data or psychiatric comorbidity between the group with sleep delay and the group with normal sleep onset were detected. Decreased total sleep time, sleep efficiency, REM sleep and prolonged REM sleep latency were observed in patients with delayed sleep onset. Conclusion PSG showed delayed sleep timing in only 38% of patients with a diagnosis of DSWPD based on diagnostic criteria of the International Classification of Sleep Disorders (ICSD-3). We suggest that PSG can provide useful information regarding the prevailing etiology (biological versus behavioral) if dim light melatonin onset testing is not available.
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المؤلفون: Jeffrey R. Strawn, Jeffrey A. Mills, John T. Walkup, Tara S. Peris, Vikram Suresh, Paul E. Croarkin
المصدر: J Affect Disord
مصطلحات موضوعية: Male, Adolescent, medicine.medical_treatment, Serotonin reuptake inhibitor, Psychological intervention, Anxiety, behavioral disciplines and activities, Article, mental disorders, medicine, Humans, Child, Depressive Disorder, Major, Fluoxetine, Sertraline, Cognitive Behavioral Therapy, Depression, business.industry, digestive, oral, and skin physiology, Bayes Theorem, medicine.disease, Anxiety Disorders, Paroxetine, Cognitive behavioral therapy, Psychiatry and Mental health, Clinical Psychology, Treatment Outcome, Major depressive disorder, medicine.symptom, business, Selective Serotonin Reuptake Inhibitors, medicine.drug, Clinical psychology
الوصف: BACKGROUND: Treatment studies of children and adolescents with internalizing disorders suggest that the combination of a selective serotonin reuptake inhibitor (SSRI) and cognitive behavioral therapy (CBT) consistently produces greater improvement than either treatment alone. We sought to determine how response to combined treatment varies across disorders (anxiety versus depression), and by specific patient characteristics. METHODS: Three large National Institutes of Health-funded trials of children and adolescents with major depression (n=2) and anxiety disorders (n=1) were evaluated, each comparing CBT + SSRI to SSRI only, Bayesian Hierarchical Models (BHMs) were used, for endpoint response, time course of response and predictors of response in participants who received SSRI or SSRI+CBT. RESULTS: SSRI+CBT significantly decreased symptoms by week 4 (p
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