نتائج البحث - "PHOSPHODIESTERASES"

1

The effect of phosphodiesterase-5 inhibitors on uteroplacental and fetal cerebral perfusion in pregnancies with fetal growth restriction: A systematic review and meta-analysis

المؤلفون: Kamran Hessami, Alireza A. Shamshirsaz, Mauro Cozzolino

المصدر: European Journal of Obstetrics & Gynecology and Reproductive Biology. 267:129-136

مصطلحات موضوعية: Middle Cerebral Artery, medicine.medical_specialty, medicine.drug_mechanism_of_action, Sildenafil, Gestational Age, Ultrasonography, Prenatal, Umbilical Arteries, chemistry.chemical_compound, Pregnancy, medicine.artery, Internal medicine, medicine, Humans, Cerebral perfusion pressure, Cyclic Nucleotide Phosphodiesterases, Type 5, Fetus, Fetal Growth Retardation, business.industry, Obstetrics and Gynecology, Ultrasonography, Doppler, Phosphodiesterase 5 Inhibitors, Tadalafil, Perfusion, Reproductive Medicine, chemistry, Cerebrovascular Circulation, cGMP-specific phosphodiesterase type 5, Middle cerebral artery, Cardiology, Female, business, Phosphodiesterase 5 inhibitor, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5440311151f2b2aa0cf6603b620216bf
https://doi.org/10.1016/j.ejogrb.2021.10.032

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2

Phosphodiesterase 2A and 3B variants are associated with primary aldosteronism

المصدر: Endocr Relat Cancer

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0e5c3b64ea5d8c98d4e2f12830b6c5f
https://doi.org/10.1530/erc-20-0384

3

Evidence for reprogramming of monocytes into reparative alveolar macrophages in vivo by targeting PDE4b

المؤلفون: Ian Rochford, Lakshmi Yalagala, Dolly Mehta, Zahid Akhter, Somenath Banerjee, Jagdish Chandra Joshi, Mumtaz Anwar, Sheikh Rayees

المصدر: Am J Physiol Lung Cell Mol Physiol

مصطلحات موضوعية: Lipopolysaccharides, Male, Transcriptional Activation, Pulmonary and Respiratory Medicine, Pathology, medicine.medical_specialty, Neutrophils, Physiology, Acute Lung Injury, Vascular permeability, Neutrophilic inflammation, Lung injury, Monocytes, Capillary Permeability, Mice, PDE4B, In vivo, Physiology (medical), Macrophages, Alveolar, Cyclic AMP, Animals, Medicine, Inflammation, Lung, NFATC Transcription Factors, business.industry, Cell Differentiation, Cell Biology, Adoptive Transfer, Cyclic Nucleotide Phosphodiesterases, Type 4, Mice, Inbred C57BL, Sentinel cell, medicine.anatomical_structure, Female, Phosphodiesterase 4 Inhibitors, business, Rolipram, Reprogramming, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0a2488b3c02bc3bf9e8de42715cdef5
https://doi.org/10.1152/ajplung.00145.2021

4

Phosphodiesterase-5 inhibitor sildenafil attenuates kidney injury induced by Bothrops alternatus snake venom

المؤلفون: Pedro Everson Alexandre de Aquino, Rui Seabra Ferreira Junior, Aline Diogo Marinho, Helena Serra Azul Monteiro, Antônio Rafael Coelho Jorge, Ana Paula Negreiros Nunes Alves, Francisco Assis Nogueira Júnior, João Alison de Moraes Silveira, Roberta Jeane Bezerra Jorge

المساهمون: Federal University of Ceara, Universidade Estadual Paulista (UNESP)

المصدر: Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcd0f13fcb26b351191449d4f20a1783
https://doi.org/10.1016/j.toxicon.2021.08.024

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5

Increased bleeding risk with phosphodiesterase‐5 inhibitors after left ventricular assist device implantation

المؤلفون: Arjang Ruhparwar, Aiste-Monika Jakstaite, Peter Luedike, Maria Papathanasiou, Bastian Schmack, Nikolaus Pizanis, Alexander Weymann, Matthias Riebisch, Markus Kamler, Tienush Rassaf

المصدر: ESC Heart Failure, Vol 8, Iss 4, Pp 2419-2427 (2021)
ESC Heart Failure

مصطلحات موضوعية: Male, Gastrointestinal bleeding, medicine.medical_specialty, Sildenafil, Ventricular Dysfunction, Right, medicine.medical_treatment, Medizin, 030204 cardiovascular system & hematology, Tadalafil, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Original Research Articles, medicine, Clinical endpoint, Humans, Diseases of the circulatory (Cardiovascular) system, Cumulative incidence, Prospective Studies, Original Research Article, 030212 general & internal medicine, Prospective cohort study, Retrospective Studies, Cyclic Nucleotide Phosphodiesterases, Type 5, Heart Failure, business.industry, Incidence (epidemiology), Phosphodiesterase‐5 inhibitors, Middle Aged, Phosphodiesterase 5 Inhibitors, medicine.disease, Surgery, Editorial, chemistry, Ventricular assist device, Heart failure, RC666-701, Left ventricular assist devices, Heart-Assist Devices, Cardiology and Cardiovascular Medicine, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0eb29f696a03eb92191c49dbea1f17a8
https://doaj.org/article/0b84ac4f6974497584c2bd2465219e34

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6

Ameliorative effect of phosphodiesterase 4 and 5 inhibitors in deoxycorticosterone acetate‐salt hypertensive uni‐nephrectomized KKA y mice

المؤلفون: Fumi Shimizu, Mitsugi Ookawara, Guido Hanauer, Kimio Tohyama, Masatoshi Hazama, Tomoya Sano, Yasunori Nio, Takanori Matsuo, Hisashi Anayama, Sachio Shibata, Midori Yamasaki

المصدر: The FASEB Journal. 34:14997-15014

مصطلحات موضوعية: Male, 0301 basic medicine, medicine.medical_specialty, Angiotensin receptor, Tyramine, Cardiomegaly, Acetates, Sodium Chloride, urologic and male genital diseases, Biochemistry, Sildenafil Citrate, Diabetic nephropathy, Mice, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Irbesartan, Mineralocorticoids, Internal medicine, Genetics, medicine, Animals, Renal Insufficiency, Desoxycorticosterone, Molecular Biology, Cyclic Nucleotide Phosphodiesterases, Type 5, Mice, Knockout, Creatinine, Kidney, business.industry, Anti-Inflammatory Agents, Non-Steroidal, Glomerulosclerosis, Phosphodiesterase 5 Inhibitors, medicine.disease, Cyclic Nucleotide Phosphodiesterases, Type 4, Mice, Inbred C57BL, 030104 developmental biology, Endocrinology, medicine.anatomical_structure, chemistry, Hyperglycemia, cGMP-specific phosphodiesterase type 5, Hypertension, Female, business, 030217 neurology & neurosurgery, Nephrosclerosis, Biotechnology, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::005f970e38618f971a9ead3d067aaa16
https://doi.org/10.1096/fj.202001084r

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7

Circ_0091702 relieves lipopolysaccharide (LPS)-induced cell injury by regulating the miR-182/PDE7A axis in sepsis

المؤلفون: Shimin Dong, Xinliang Zhang

المصدر: Bioscience, Biotechnology, and Biochemistry. 85:1962-1970

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83e421bd9021f2803065bb4320c3e322
https://doi.org/10.1093/bbb/zbab100

8

circPDE4B prevents articular cartilage degeneration and promotes repair by acting as a scaffold for RIC8A and MID1

المؤلفون: Xiangqian Fang, Yute Yang, Qingxin Wang, Shunwu Fan, Panyang Shen, Bin Fang, Shuying Shen, Jun Ma, Peihua Shi, Kefan Wang

المصدر: Annals of the Rheumatic Diseases

مصطلحات موضوعية: Cartilage, Articular, 0301 basic medicine, MAPK/ERK pathway, Proteasome Endopeptidase Complex, Cell Survival, Immunoprecipitation, Ubiquitin-Protein Ligases, Immunology, chondrocytes, General Biochemistry, Genetics and Molecular Biology, Mice, 03 medical and health sciences, 0302 clinical medicine, Rheumatology, Downregulation and upregulation, Osteoarthritis, Animals, Guanine Nucleotide Exchange Factors, Humans, Regeneration, Immunology and Allergy, Medicine, Protein kinase A, business.industry, Ubiquitination, RNA, RNA, Circular, Cyclic Nucleotide Phosphodiesterases, Type 4, Cell biology, 030104 developmental biology, biological therapy, 030220 oncology & carcinogenesis, Proteolysis, RNA splicing, RNA-Binding Protein FUS, Guanine nucleotide exchange factor, business, Protein Processing, Post-Translational

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e7799b910239061be38e59c7e8eb6f2
https://doi.org/10.1136/annrheumdis-2021-219969

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9

The cAMP-phosphodiesterase 4 (PDE4) controls β-adrenoceptor- and CFTR-dependent saliva secretion in mice

المؤلفون: Abigail Boyd, Ileana V. Aragon, Dylan Southers, Wito Richter, Lina Abou Saleh

المصدر: Biochem J

مصطلحات موضوعية: Male, Saliva, medicine.medical_specialty, Phosphodiesterase Inhibitors, Phosphodiesterase 3, Saliva secretion, Cystic Fibrosis Transmembrane Conductance Regulator, Propranolol, Biochemistry, Article, Mice, 03 medical and health sciences, 0302 clinical medicine, stomatognathic system, Internal medicine, Major Salivary Gland, Receptors, Adrenergic, beta, Muscarinic acetylcholine receptor, medicine, Animals, Humans, Molecular Biology, 030304 developmental biology, 0303 health sciences, Salivary gland, business.industry, Phosphodiesterase, Cell Biology, Cyclic Nucleotide Phosphodiesterases, Type 4, Mice, Inbred C57BL, medicine.anatomical_structure, Endocrinology, Salivation, business, 030217 neurology & neurosurgery, Signal Transduction, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a3084f729594a7a7a9baac14d30f17b
https://doi.org/10.1042/bcj20210212

10

Characterization of LY2775240, a selective phosphodiesterase‐4 inhibitor, in nonclinical models and in healthy subjects

المؤلفون: Sean E. Sissons, Cody J. Buckman, Mary S. Zuniga, Shweta Urva, Karen Cox, Yanfei Ma, Stephen Ho, Diane Philips, Jean Lim, Dipak R. Patel, Daniel J. Dairaghi

المصدر: Clinical and Translational Science, Vol 14, Iss 3, Pp 1037-1048 (2021)
Clinical and Translational Science

مصطلحات موضوعية: Adult, Male, 030213 general clinical medicine, Drug Evaluation, Preclinical, Administration, Oral, RM1-950, Pharmacology, 030226 pharmacology & pharmacy, General Biochemistry, Genetics and Molecular Biology, Article, law.invention, 03 medical and health sciences, Mice, 0302 clinical medicine, Pharmacokinetics, law, Psoriasis, medicine, Animals, Humans, General Pharmacology, Toxicology and Pharmaceutics, Adverse effect, Enzyme Assays, Clinical pharmacology, Cross-Over Studies, business.industry, General Neuroscience, Research, General Medicine, Articles, Drugs, Investigational, Middle Aged, medicine.disease, Macaca mulatta, Healthy Volunteers, Cyclic Nucleotide Phosphodiesterases, Type 4, Thalidomide, Tolerability, Pharmacodynamics, Female, Apremilast, Phosphodiesterase 4 Inhibitors, Therapeutics. Pharmacology, Public aspects of medicine, RA1-1270, business, Ex vivo, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::065a98f367138609cf7eaff098736997
https://doaj.org/article/26338cb3724a46be895644ae7734a730

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