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1
المؤلفون: Joel Cassel, Jessica C. Leung, Subhasree Basu, Hsin-Yao Tang, David W. Speicher, Rebecca A. Moeller, Adi Narayana Reddy Poli, Donna L. George, Keerthana Gnanapradeepan, Andrew V. Kossenkov, Dmitry I. Gabrilovich, Julia I-Ju Leu, Joshua L.D. Parris, Tetyana Martynyuk, Emilio Sanseviero, Qin Liu, Alexandra Indeglia, Joseph M. Salvino, Madeline Good, Maureen E. Murphy, Thibaut Barnoud
المصدر: Cancer Res
مصطلحات موضوعية: Male, 0301 basic medicine, Cancer Research, Colorectal cancer, Antineoplastic Agents, Mitochondrion, Biology, Article, 03 medical and health sciences, Adenosine Triphosphate, 0302 clinical medicine, Immune system, Mice, Inbred NOD, medicine, Alarmins, Animals, Humans, Cytotoxic T cell, HSP70 Heat-Shock Proteins, HMGB1 Protein, Cell-Free System, medicine.disease, Xenograft Model Antitumor Assays, High-Throughput Screening Assays, Mitochondria, Mice, Inbred C57BL, Mitochondrial toxicity, 030104 developmental biology, Proteostasis, Oncology, 030220 oncology & carcinogenesis, Cancer cell, Cancer research, Immunogenic cell death, Colorectal Neoplasms, HT29 Cells
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::608c24a8acfaf37caae326dbd2048970
https://doi.org/10.1158/0008-5472.can-20-0397 -
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المؤلفون: Xiaowei Xu, Nan Cheng, Anupma Nayak, Gretchen M. Alicea, Ezra Baraban, Qing Chen, Zachary T. Schug, Ashani T. Weeraratna, Joshua L.D. Parris, Ke Xu, Maureen E. Murphy, Caroline E. Perry, Yongkang Zou, Meenhard Herlyn, Pulak Ray, Andrea Watters
المصدر: Cancer Discov
مصطلحات موضوعية: 0301 basic medicine, medicine.disease_cause, Article, Mice, 03 medical and health sciences, 0302 clinical medicine, Cell Movement, Cell Line, Tumor, medicine, Animals, Humans, Cell Proliferation, Brain Neoplasms, Cell growth, business.industry, Gene Expression Profiling, Melanoma, Cancer, medicine.disease, PPAR gamma, 030104 developmental biology, Oncology, Cell culture, Astrocytes, 030220 oncology & carcinogenesis, Cancer cell, Fatty Acids, Unsaturated, Cancer research, Signal transduction, Carcinogenesis, business, Neoplasm Transplantation, Signal Transduction, Brain metastasis
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ae7419b375ae37cf74544b1d668ccad
https://doi.org/10.1158/2159-8290.cd-19-0270 -
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المؤلفون: Julia I-Ju Leu, Tian Tian, Meenhard Herlyn, Zhi Wei, Maureen E. Murphy, Donna L. George, Thibaut Barnoud, Gao Zhang
المصدر: Oncotarget
مصطلحات موضوعية: 0301 basic medicine, Mitochondrion, Biology, medicine.disease_cause, Poly(A)-Binding Protein I, Mitochondrial Proteins, 03 medical and health sciences, Adenosine Triphosphate, Stress, Physiological, Cell Line, Tumor, Neoplasms, medicine, Humans, chaperone, PABPC1, HSP70 Heat-Shock Proteins, HSP70, Membrane Potential, Mitochondrial, Genetics, proteostasis, Prognosis, Mitochondria, 3. Good health, Cell biology, HSPA1A, 030104 developmental biology, Proteostasis, Oncology, Proteasome, Cell culture, Chaperone (protein), Cancer cell, biology.protein, Carcinogenesis, Proteasome Inhibitors, Protein Binding, Research Paper
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f258a9b4ecd04c750ab8df768bf1b264
https://doi.org/10.18632/oncotarget.17321 -
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المؤلفون: Subhasree Basu, Maureen E. Murphy, Anna Budina-Kolomets, Jaruwan Chatwichien, Jeffrey D. Winkler
المصدر: Bioorganic & Medicinal Chemistry Letters. 26:4884-4887
مصطلحات موضوعية: 0301 basic medicine, Programmed cell death, Lung Neoplasms, Clinical Biochemistry, Pharmaceutical Science, Apoptosis, Biochemistry, Article, 03 medical and health sciences, Carcinoma, Non-Small-Cell Lung, Cell Line, Tumor, Proto-Oncogene Proteins, Puma, Drug Discovery, medicine, Humans, Cytotoxic T cell, p53 upregulated modulator of apoptosis, Molecular Biology, biology, Chemistry, Organic Chemistry, Autophagy, biology.organism_classification, Cell biology, 030104 developmental biology, Mechanism of action, Cancer cell, biology.protein, Cancer research, Molecular Medicine, biological phenomena, cell phenomena, and immunity, medicine.symptom, Apoptosis Regulatory Proteins, Dimerization, Carbolines
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المؤلفون: Karl Heinz Tomaszowski, Jessica W. Luzwick, Maureen E. Murphy, Soyoung Park, Sunetra Roy, Katharina Schlacher, Jun Li
المصدر: eLife
eLife, Vol 7 (2018)مصطلحات موضوعية: p53, 0301 basic medicine, Genome instability, Mouse, replication stress response, RAD52, Cell, replication fork restart, DNA-Directed DNA Polymerase, Mice, chemistry.chemical_compound, Homeostasis, Biology (General), replication protection, Genetics, General Neuroscience, MRE11, General Medicine, 3. Good health, medicine.anatomical_structure, Genes and Chromosomes, Medicine, Insight, Human, DNA Replication, QH301-705.5, Science, Biology, Genomic Instability, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Control of chromosome duplication, medicine, Animals, Humans, cancer, Gene, General Immunology and Microbiology, DNA replication, BRCA2, genome instability, Rad52 DNA Repair and Recombination Protein, 030104 developmental biology, chemistry, Drug Resistance, Neoplasm, Mutation, Cancer cell, replication fork, Tumor Suppressor Protein p53, DNA
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المؤلفون: Prashanth Gokare, Niklas Finnberg, Jenny Dai, Phillip H. Abbosh, Maureen E. Murphy, Wafik S. El-Deiry
المصدر: Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Scientific Reportsمصطلحات موضوعية: Male, 0301 basic medicine, Cell Survival, lcsh:Medicine, DNA-Activated Protein Kinase, Models, Biological, Thymidylate synthase, Article, Gene Expression Regulation, Enzymologic, Mice, 03 medical and health sciences, 0302 clinical medicine, Tandem Mass Spectrometry, Cell Line, Tumor, Dihydropyrimidine dehydrogenase, Animals, Humans, lcsh:Science, Protein kinase A, Psychological repression, Dihydrouracil Dehydrogenase (NADP), Mice, Knockout, Polymorphism, Genetic, Multidisciplinary, biology, lcsh:R, Nuclear Proteins, Thymidylate Synthase, Molecular biology, Chromatin, DNA-Binding Proteins, Disease Models, Animal, Pyrimidines, 030104 developmental biology, Histone, 030220 oncology & carcinogenesis, Cancer cell, biology.protein, lcsh:Q, DPYD, Tumor Suppressor Protein p53, Colorectal Neoplasms, Chromatography, Liquid, Protein Binding, Signal Transduction
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المؤلفون: K. A. Woerpel, Valerian E. Kagan, Frank M. Torti, Brent R. Stockwell, Scott J. Dixon, Simone Fulda, Jason Park, Suzy V. Torti, Ashley I. Bush, Donna D. Zhang, Michael Overholtzer, José Pedro Friedmann Angeli, Susan Gascon, Shinya Toyokuni, Maureen E. Murphy, Andreas Linkermann, Hülya Bayır, Gabriela Carolina Pagnussat, Kay Noel, Qitao Ran, Stavroula K. Hatzios, Daolin Tang, Atsushi Oyagi, Marcus Conrad, Craig S. Rosenfeld, Konstantin Salnikow, Xuejun Jiang
المصدر: Cell 171, 273-285 (2017)
مصطلحات موضوعية: 0301 basic medicine, Programmed cell death, Iron, Apoptosis, Biology, GPX4, medicine.disease_cause, ACSL4, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, chemistry.chemical_compound, medicine, Animals, Humans, Coenzyme Q10, Cell Death, Neurodegeneration, medicine.disease, Pufa, Ros, Cancer, Ferroptosis, Glutathione, Metabolism, Peroxidation, Cell biology, 030104 developmental biology, chemistry, Cancer cell, Carcinogenesis, Reactive Oxygen Species, Oxidation-Reduction, Oxidative stress
وصف الملف: application/pdf
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المؤلفون: Gregor M. Balaburski, Anna Budina-Kolomets, Neil Beeharry, Maureen E. Murphy, Anastasia Bondar, Timothy J. Yen
المصدر: Cancer Biology & Therapy. 15:194-199
مصطلحات موضوعية: Cancer Research, Cell cycle checkpoint, Pyridines, Antineoplastic Agents, Apoptosis, Cell Line, Tumor, Autophagy, Humans, HSP70 Heat-Shock Proteins, Adaptor Proteins, Signal Transducing, Pharmacology, Sulfonamides, biology, Cell Cycle Checkpoints, Purine Nucleosides, Cell cycle, Hsp90, HSPA1A, Cell biology, Thiazoles, Oncology, Chaperone (protein), Cancer cell, biology.protein, Molecular Medicine, Anaphase-promoting complex, Research Paper
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المؤلفون: Gao Zhang, Mark Andrake, Tim J. Yen, Donna L. George, Seth Hayik, Julia I-Ju Leu, Jessie Villanueva, Roland L. Dunbrack, Neil Beeharry, Meenhard Herlyn, Gregor M. Balaburski, Maureen E. Murphy
المصدر: Molecular Cancer Research. 11:219-229
مصطلحات موضوعية: Models, Molecular, Cancer Research, Antineoplastic Agents, HSP72 Heat-Shock Proteins, Plasma protein binding, Biology, Genomic Instability, Article, Substrate Specificity, Mice, Structure-Activity Relationship, Precursor B-Cell Lymphoblastic Leukemia-Lymphoma, Animals, Humans, Cytotoxic T cell, Structure–activity relationship, Gene silencing, Computer Simulation, Binding site, Cytotoxicity, Molecular Biology, Sulfonamides, Gene Expression Regulation, Leukemic, Neoplasms, Experimental, Protein Structure, Tertiary, Molecular Docking Simulation, Oncology, Cancer cell, Cancer research, Anaphase-promoting complex, Protein Binding
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f7fa7d24fa64262b385d93cffc95268
https://doi.org/10.1158/1541-7786.mcr-12-0547-t -
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المؤلفون: Maureen E. Murphy
المصدر: Carcinogenesis. 34(6)
مصطلحات موضوعية: Cancer Research, Protein Folding, biology, GTPase-activating protein, Apoptosis, General Medicine, Review, Protein aggregation, Prognosis, Hsp90, Cell biology, Transport protein, Hsp70, Mice, Protein Transport, Stress, Physiological, Chaperone (protein), Heat shock protein, Neoplasms, Protein Biosynthesis, Cancer cell, biology.protein, Animals, Humans, HSP70 Heat-Shock Proteins
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc1936167e4d1b02d43f0168133e3f94
https://pubmed.ncbi.nlm.nih.gov/23563090